Factors Of Depression In Patients Research Articles

Prevalence and Risk Factors of Depression in Patients with Chronic Obstructive Pulmonary Disease

Background: Due to the irreversible nature of chronic obstructive pulmonary disease (COPD), the treatment aim in patients with COPD is not to cure but to reduce the symptoms, increase lung function, and improve the quality of life. It has been suggested that depression is a common emotional disturbance in patients with COPD who are faced with a major physical impairment and embarrassing symptoms. This study evaluated the prevalence and risk factors of depression in patients with chronic obstructive pulmonary disease. Methods: A total of 59 patients with a registered diagnosis of chronic obstructive pulmonary disease were selected. Depression was assessed using the Centers for Epidemiologic Studies Depression (CES-D) scale. The quality of life was assessed using the Korean version of the St. George’s Respiratory Questionnaire. Results: The prevalence of depression was 17.0%. In the correlation model, the interaction of the FEV1% over predicted value and SGRQ score(symptom, activity, impact, overall score) was statistically significant. The interaction of the FEV 1% over predicted value and depression scale(CES-D) was also statistically significant. There was a positive correlation between the SGRQ scores(symptom, activity, impact, overall score) and the depression scale. Conclusion: The prevalence of depression in patients with chronic obstructive pulmonary disease is relatively high. The pulmonary function and the living standards were found to be significant risk factors for depression. (Tuberc Respir Dis 2008;65:191-197)

Risk Factors for Depression in Patients with Diabetes Mellitus

Risk Factors for Depression in Patients with Diabetes Mellitus

Factors associated with depressive symptoms in patients with metastases from prostate cancer

9131 Background: The purpose of this study was to identify predictive factors of depression in patients with metastases from prostate cancer. Methods: Patients with evidence of metastases from prostate cancer were prospectively screened for depression. Depressive symptoms were defined by the Beck Depression Inventory-Short Form (BDI-SF) with a low cut-off score of 4 to optimize sensitivity as a screening test (Lowe AW, 2004). Self-report questionnaires including BDI-SF were sent to pts through the mail and then given back to the oncologist. In case of a BDI-SF > 4, a consultation with a psychiatrist was proposed, so that the diagnosis of depression could be made and treatment be started. Characteristics including marital status, spiritual well-being, educational level, ongoing treatment for prostate cancer, and the presence of pain requiring analgesic therapy were registered. Results: 92 patients were prospectively enrolled of whom 54 (60%) completed the self-report questionnaires. Median age was 69 years (range: 50–84). 31 pts (54%) had castration-refractory disease, of whom 30 were receiving chemotherapy: docetaxel (n=22), carboplatin-etoposide (n=6) and doxorubicin (n=2). Eighteen patients (33%) had a BDI-SF score > 4, of whom 10 (18%) had a major depressive disorder (MDD) according to the Diagnostic and Statistical Manual of Mental Disorders IV (DSM-IV) criteria. Logistic regression analysis showed that pain requiring analgesic therapy was the only predictive factor of depressive symptoms (OR=3.75; 95% confidence interval 1.1–12.4). In patients with pain requiring treatment, the incidence of depressive symptoms and MDD was 53% and 32%, respectively. In contrast to female with advanced breast cancer (Conforti R, 2004), marital status and belief in god were not predictive factors of depressive symptoms in this population of males. Conclusions: Pain requiring analgesic treatment was the only factor significantly associated with depressive symptoms in this sample of 54 patients with metastatic prostate cancer. A screening for depression should be systematically implemented at least in this subgroup of patients. No significant financial relationships to disclose.

O-126: Risk factors for depression in patients with polycystic ovary syndrome vary by ethnicity

An increased incidence of depression has been described in patients with polycystic ovary syndrome (PCOS). Various laboratory and clinical components (LCCs) related to PCOS such as insulin resistance and hirsutism have been implicated in the increased risk. We explored the possible association of LCCs with depression risk, and the possible role of ethnicity in these associations.

Risk factors for depression in patients with epilepsy

Purpose Symptoms of depression are present in 40 to 60 percent of patients with epilepsy. Prior research indicated significant correlation between the incidence and frequency of focal seizures and clinical depression, especially in patients with temporal lobe epilepsy. Anticonvulsive drugs and psychosocial factors contribute to the occurrence of depression as well. The aim of the study was to determine the major depression risk factors in patients with epilepsy. Methods The research was conducted on 203 patients with epilepsy (117 females and 86 males), aged 18 to 50 years, with total time of illness ranging from 60 to 580 months. All subjects underwent the same research protocol, which was applied interictally. Interictal depression was diagnosed according to ICD-10 diagnostic criteria for affective and delusional disorders. The diagnosis was supported by Beck Depression Inventory (BDI), Hamilton Depression Rating Scale (HAM-D) and Montgomery-Åsberg Depression Rating Scale (MADRS). Statistical analysis included χ 2 test, Fisher’s exact test and stepwise logical regression model analysis. Results In our study 100 patients with epilepsy out of 203 suffered from concurrent depression (49.2%); 76 of them had severe depression (37.4%) and 24 patients had mild depression (11.8%). Complex partial seizures and absence of secondary generalized tonic–clonic seizures were found to be the risk factors for depression. Treatment with clonazepam, frequent hospitalizations (drug-resistancy) and lack of occupational activity were revealed to be additional significant contributing factors. Conclusions Depression in patients with epilepsy is a serious medical and social problem since it afflicts almost one half of all patients treated in epilepsy referral centers. It seems to be correlated with certain types of epileptic seizures, with high frequency of seizures, sub-optimal pharmacologic treatment and lack of occupational and social activity.

Incidence and predictive factors of depression in patients with metastatic breast cancer: A prospective study

8165 Background: Although some reports suggest that the incidence of depression in patients with metastatic breast cancer is high, only a few studies specifically focus on the predictive factors for depression. The identification of predictive factors for depression in cancer patients could help to screen it. In the present study, we have evaluated the incidence and predictive factors for depression in patients with metastatic breast cancer. Methods: A Beck depression inventory short form was given to 178 patients with metastatic breast cancer followed at the Institut Gustave Roussy between december 2003 and april 2004. We looked at the correlation between age, mastectomy, ongoing chemotherapy, site of metastases, marital status, belief in god and the beck score. Patients who presented a Beck score above 4 were considered as depressed. Results: 132 patients replied to the questionnaire (74%). Of these patients, 65% received chemotherapy at the time of evaluation and 31% presented a liver metastasis. A Beck score >4 was observed in 33 patients (25% of questionnaires). Age, locoregional treatment, ongoing chemotherapy and site of metastases did not predict the Beck score. The only predictive factors for depression were the marital status (p=0.04) and the lack of god belief (p=0.04). Although a psycho-oncology service was available in the hospital, only 5 patients (15%) who presented a beck score >4 were followed by a specialist in psycho-oncology. Conclusion: This study confirms that depression is a frequent and underdiagnosed situation in patients with metastatic breast cancer, and suggests that social and cultural factors are more important that clinical characteristics to predict depression. No significant financial relationships to disclose.

Predicting factors of depression in patients with primary hypertension: a community-based study

OBJECTIVETo investigate the factors that may predict the occurrence of depression in patients with primary hypertension.METHODSWe conducted a cross-sectional survey on 891 hypertensive patients and 651 normal subjects (control group) from a single community. Zung self-rating depression scale (SDS) was applied to evaluate the symptoms of depression, which was diagnosed when the SDS score was >41.RESULTSThere was no significant difference in gender distribution (female, 48.5 vs. 47.6%) and age (65.3±9.2 vs. 64.0±7.9 years) between the hypertensive control groups (P>0.05). Depression was diagnosed in 139 hypertensive patients (15.6%) and 27 (4.2%) control subjects (P<0.01). The average SDS score was higher in patients with hypertension duration of more than 3 years (33.3±9.0 vs. 30.6±7.6, P<0.001), in patients with severe hypertension (44.0±7.8 vs. 28.9±4.9, P<0.001) and in patients with a history of hospitalization for cardiovascular disorders (38.1±9.3 vs. 32.0±8.4, P<0.001). Multivariate regression analysis showed that the degree and the duration of hypertension, as well as hospitalization history, were independent predictors of depression in the hypertensive patients.CONCLUSIONSHypertension is associated with a higher prevalence of depression that can be predicted by the duration and severity of hypertension as well as a history of hospitalization.

Depression with irritability in patients undergoing coronary artery bypass graft surgery: the cardiologist’s role

The purpose of this study was to investigate the determinants and maintenance factors of depression in patients undergoing coronary artery bypass graft (CABG) surgery. Fifty CABG candidates were selected randomly for evaluation before and after surgery. Depressive disorders occurred in 22.0% of the patients preoperatively and 21% postoperatively. Irritability as a symptom was more prevalent in depressed than nondepressed patients preoperatively ( P=.04) and postoperatively ( P=.006). Although depression was the most prevalent diagnosis in the patients’ psychiatric histories and evaluations, benzodiazepines were prescribed more frequently than antidepressants (70% vs 3%). Cardiologists should consider that the irritability in some patients undergoing CABG may obscure the diagnosis of depression. The correct recognition of depression is essential to reduce inappropriate benzodiazepine prescription and to apply appropriate treatment.

Prevention of Depression and Anxiety in Patients with Cardiovascular Disease

Depression and anxiety are common in patients with cardiovascular disease (CVD). Depending on the time and method of assessment, depression occurs in 9-27% of patients, and anxiety is nearly universal in patients who have had an acute myocardial infarction (MI), at least during hospitalization. Depression has a major impact on mortality, morbidity and functional recovery and there is evidence that treating depression may improve outcome. While few studies have examined risk factors for depression in patients with CVD, the risk factors for depression identified in other clinical populations, such as previous history of depression, are undoubtedly relevant to CVD patients. Our data suggest that women are much more likely to be depressed than men, and to remain so in the course of recovery. Few strategies have been evaluated for primary prevention of depression or anxiety, even in the general population, and no studies have been undertaken in patients with CVD. While primary prevention of depression in postM...