Driven by climate change and increased human activities, the frequency and intensity of extreme rainfall events are increasing, leading to increased risk of water erosion on slopes in karst rocky desertification (KRD) areas. However, the driving factors (rainfall intensity, slope gradient, and the degree of underground fissure pore), characteristics, and dynamic mechanisms of rill erosion on KRD slopes under extreme rainfall have received limited attention. A rainfall simulation experiment was performed to investigate the driving factors of rill erosion on KRD slopes under extreme rainfall events. The experiments were conducted using an erosion flume (4 m long, 1.5 m wide and 0.35 m deep) with five rainfall intensities (50, 105, 115, 125 and 145 mm·h−1), three-level slope gradients (5°, 15° and 25°), and three typical degrees of underground pore fissure (1 %, 3 % and 5 %). The results showed that extreme rainfall significantly stimulated the formation and development of rill erosion on KRD slopes. In particular, rainfall intensity and slope gradient significantly affected rill erosion (p < 0.05), whereas the degree of underground pore fissure did not have any distinct effect. Increasing rainfall intensity intensified rill erosion by significantly (p < 0.05) promoting the rill density, total rill surface area, and longest of rill length. With increasing slope gradient, the rill density, rill distribution density, and average rill depth significantly increased (p < 0.05). Moreover, extreme rainfall events exacerbated surface soil erosion by enhancing the hydrodynamic characteristics of slope runoff. Rill erosion was most sensitive to the shear stress of runoff, and rill density was found to be the most suitable rill index for describing surface soil erosion on the slope under extreme rainfall. The findings provide valuable insights into the characteristics and mechanisms of soil erosion in karst regions under future climate warming.