Mobility Factor Research Articles

Championing Social Mobility

Championing Social Mobility

A reliable position-based routing scheme for controlling excessive data dissemination in vehicular ad-hoc networks

In the past two decades, the automotive industry has undergone tremendous changes, as this field has become one of the fastest developing and growing fields, especially with the progress of global digitization and massive research related to networks. So, it comes as no surprise that self-driving vehicles are ubiquitous mainly relying on Vehicular ad-hoc networks (VANETs). This transformation ensures improved road navigation and traffic congestion avoidance by relying on Rapid Data Deployment (DD). On the other hand, although DD achieves high connection reliability, it may affect network bandwidth and performance. In addition, excessive DD causes frequent link outages resulting in reduced data delivery, massive packet loss, and premature end of network life. This paper presents an integrated architecture proposal for a vehicle dynamic assistance architecture, based on reliable methods to ensure steering accuracy while minimizing the energy expended for controlling the DD rate via VANETs. The proposed architecture integrates between Software-Defined Networks (SDN) and fog computing based on dealing with the mobility factors that exploit vehicle communication behaviors. Such integration will aid in improving network performance in terms of packet delivery and DD. The study also discusses how to take into consideration the Euclidean distance, geographical routing information, residual power ratio, and latency time to maximize network stability and avoid possible link disruption. The simulation results prove that there is a 62% to 70% enhancement of the whole power consumption and network throughput, depending on the implementation of the proposed position-based routing approach. Interestingly, the proposed routing protocol is a dual-phase routing protocol with a 90% of SDN data packet delivery ratio and an 82% of SDN data loss reduction. So, when the SDN fails to deliver packets, the proposed position-based routing handles them as a parallel mechanism of SDN.

Ecological assessment of soil contamination by heavy metals affected in the past by the lead–zinc mining and processing complex in Kentau, Kazakhstan

Polymetallic ore processing plants are serious sources of heavy metal pollution. The present study examined the degree of pollution of surface soils with the metals zinc, cadmium, lead, and copper in the single-industry town of Kentau, Kazakhstan, where an enterprise for the processing of lead-zinc ore has been operating for a long time. This enterprise ceased operations in 1994, and this study may be of interest in terms of assessing the current ecological state of urban soils after a 27-year period of possible soil self-cleaning processes. The study showed that the surface soils of Kentau retain fairly high concentrations of metals. The maximum detected concentrations of zinc, cadmium, lead, and copper were 592mg/kg, 1.651mg/kg, 462mg/kg, and 82.5mg/kg, respectively. According to the classification of the geoaccumulation index, the soils of the town belong to pollution classes II, III, and IV with moderate and strong pollution. The calculated potential ecological risk factor indicates that cadmium poses a considerable potential ecological risk, while lead showed a moderate ecological risk. In general, according to the obtained values of potential ecological risk factors, metals can be arranged in the following order: Cd > Pb > Zn > Cu. In this study, a five-step sequential extraction procedure by the method of A. Tessier was used, and the mobility factors of metals were calculated. Based on the data obtained, it was found that cadmium and lead have the highest mobility and, consequently, availability for biota in modern conditions, which may pose a potential risk to public health in the town.

A novel pollution index to assess the metal bioavailability and ecological risks in sediments

The chemical forms of metals in sediments of ports around Taiwan were investigated using sequential extraction. Based on the availability of different chemical forms, novel indices such as bioavailability, mobility, availability, and availability risk of metals in sediments were developed. The results showed that Co, Zn, Pb, Mn, and Cu were mainly present in available forms (49–84 %), and the proportion of oxidative or reductive fractionation was the highest. This suggests that the redox potential is a major factor for metal mobility in the sediments. The results from the proposed indexes showed that metals in sediments have low bioavailability but high to very high mobility and availability. Primarily, the proposed index is more appropriate, as the current index for assessing total metal content may overestimate the level of risk. The indexes established can comprehensively evaluate the bioavailability, mobility, availability, and ecological risk of metals in sediments.

Modern Realities of Foreign Educational Migration

The study analyzed educational migration in Russia. Migration is considered from the standpoint of an integrated indicator that reflects complex socio-economic processes in society. The factors of territorial mobility of the population are listed. Under their influence, the directions, dynamics, intensity and consequences of migration for donor and recipient countries change. The place and role of educational migration in the modern world are shown. The study examined the structure and dynamics of the number of foreign students studying in the universities of the Russian Federation. The directions of tough competitive struggle of national educational models in the international market of educational services and rating indicators for evaluating the activities of universities are analyzed. It is noted that the West conducts unfair competition in relation to Russian universities and the entire education system, which manifests itself in sanctions pressure, the exclusion of Russia from the Bologna process, the refusal to nostrify educational documents, etc. It is emphasized that external educational migration to a certain extent can be considered as a form of brain drain. The largest recipient countries of foreign students are indicated, which include the USA, Great Britain, China, Canada, Australia, and France.

Predictors of mobility among women engaged in commercial sex work in Uganda using generalized estimating equations model.

Women engaged in commercial sex work (WESW) are at a higher risk of acquiring and transmitting HIV. WESW are highly mobile, and their mobility may increase their economic status, and increased access to healthcare and other social services. However, it may also facilitate the spread of HIV infection from higher to lower prevalence regions. This study examined the predictors of mobility among WESW in Uganda using a generalized estimating equations model. We defined and measured mobility as the change in residence by WESW between baseline, 6months, and 12months follow-up. Participants who changed places were considered mobile, and those who never changed were non-mobile. We used data from a longitudinal study, which recruited 542 WESW from Southern Uganda aged 18-55years and constructed a Generalized Estimating Equations Model. Findings show that 19.6% of WESW changed residence between baseline and 6months of follow-up and 26.2% (cumulative) between baseline and 12months of follow-up. Older women (OR = 0.966, 95% CI = 0.935, 0.997) were associated with decreased odds of mobility, whereas WESW who were HIV positive (OR = 1.475, 95% CI = 1.078, 2.018) and those from large households (OR = 1.066, 95% CI = 1.001, 1.134) were associated with increased odds of mobility. WESW residing in rural areas (OR = 0.535, 95% CI = 0.351, 0.817) were associated with decreased odds of mobility compared to those from fishing sites. The results indicate risk factors for mobility, further research is needed to determine the directionality of these factors in order to design interventions addressing mobility among WESW.

Prediction of mobilized hematopoietic stem cell yield in patients with multiple myeloma: Usefulness of whole-body MRI-derived indices.

High-dose chemotherapy followed by autologous stem cell transplant is the mainstay of treatment for multiple myeloma (MM). The purpose of this study was to evaluate the ability of MRI-derived indices to predict mobilized hematopoietic stem cell yield. In this exploratory pilot work, we retrospectively analyzed 38 mobilization procedures for MM. Successful mobilization procedure was defined as a total yield of >4.0×106 CD34+ cells/kg. Univariate and multivariate analyses were performed to identify factors with a significant effect on successful mobilization from among clinical characteristics including number of prior lines of therapy, period from diagnosis to harvest, type of monoclonal protein (M protein); and radiological characteristics including total diffusion volume (tDV), median apparent diffusion coefficient (ADC) of tDV, and mean fat fraction of bone marrow calculated by MRI. Univariate analyses showed that relatively poor mobilization was significantly associated with M protein of Bence-Jones type and with median ADC of tDV (P = 0.02 and P = 0.004, respectively). Multivariate analyses using these two indices showed that median ADC of tDV was a significant predictive factor for adequate mobilization (P = 0.01), with an area under the curve of 0.784 (cutoff value, 1.18×10-3 mm2/s; sensitivity, 72.7%; specificity, 87.5%). The present data indicate that median ADC of tDV is a predictive factor for relatively poor mobilization of hematopoietic stem cells in MM patients undergoing autologous stem cell transplant.

Work-Related Pull Factors and Mechanisms for Attracting Internal Migrants to the Kaliningrad Region

Introduction. The importance of economic security issues for migration-attractive regions, especially the exclave Kaliningrad region, is growing. Increasing migration gain from Russia’s regions both brings obvious benefits and poses additional challenges. These include those related to the influx of workers whose professional qualifications do not suit the needs of the regional labour market. Thus, the article aims to analyze the compliance of the mechanisms for regulating internal migration with the work-related pull factors to ensure the Kaliningrad region’s economic security. Materials and Methods. The study relies on Kaliningradstat’s regional migration data for 2014–2021 and the interviews with representatives of various sectors of the regional economy, including migrants, conducted by the authors in the summer of 2022. The paper provides systematized and structured results of the content analysis of various sources on the implementation of labour policy and, in particular, the policy of attracting workforce (information and reference portals and websites of international, national and regional institutions, official statistical data by IOM and Rosstat). Results. Drawing on the example of the Kaliningrad region, the study considers several understaffed fields of occupation, including medicine, research and education, ICT, and small and medium-sized enterprises. Based on international and Russian research it analyses work-related mobility factors for each of them. It also classifies the practice of using external and internal migration selection mechanisms. Discussion and Conclusion. Based on the survey of migrants and employers in the Kaliningrad region, the study develops and discusses a list of pull factors and mechanisms for each considered workforce group that can be used to design policies for attracting workforce to the Kaliningrad region. The study results can be used in Russian regions willing to attract in-demand specialists.

Significant difference in the efficacies of silicon application regimes on cadmium species and environmental risks in rice rhizosphere

Silicon (Si) is commonly applied as base-fertilizer or foliar-topdressing to palliate the uptake-translocation-accumulation of cadmium (Cd) in rice through Si–Cd antagonism. However, little is known about the fate of Cd in rice rhizosphere soil and its eco-environmental effects under different Si treatments. Here, systematic works had been carried out to elucidate the Cd species, soil properties, and environmental risks in rice rhizosphere driven by different Si soil-fertilization regimes including CK (without Si-addition), TSi (added before transplanting stage), JSi (added at jointing stage), and TJSi (split into two equal parts, added half before transplanting and another half at jointing stage). Results showed that TJSi outperformed the rest of fertilization regimes. The solid-phase-Cd concentrations treated with TSi, TJSi and JSi were increased by 4.18%, 5.73% and 3.41%, respectively, when compared to CK. The labile Cd (F1+F2) proportion of TJSi was reduced by 16.30%, 9.30% and 6.78%, respectively, when compared to CK, TSi, and JSi. Simultaneously, the liquid-phase-Cd concentration was appreciably suppressed by TJSi throughout the rice lifecycle, while TSi mainly abated Cd dissociation during the vegetative period, and JSi attenuated it during the grain-filling stage. The mobility factor of Cd treated with TJSi was the lowest, which was significantly lower than that of TSi (9.30%) and JSi (6.78%), respectively. Similarly, the oral exposure risk of TJSi was reduced by 4.43% and 32.53%; and the food-chain exposure risk of TJSi was decreased by 13.03% and 42.78%. Additionally, TJSi was the most effective in promoting enzyme activities and nutrient content in rhizosphere soil. Overall, TJSi is more positive and sustainable than TSi and JSi in reconstructing Cd-contaminated rhizosphere environments and abating the environmental risks of Cd. Agronomic practices in Cd-contaminated paddy soils can be informed by applying Si-fertilizer separately before transplanting and at jointing stage to achieve soil welfare and food security.

Geochemical speciation, ecological risk, and source identification of heavy metal(loid)s in sediments and waters from Musa Estuary, Persian Gulf

Surface sediment and water samples from 12 stations were collected from Musa Estuary. Metals concentrations (Al, As, Cd, Co, Cr, Cu, Fe, Mn, Ni, Pb, Sb, and Zn) were analyzed by ICP-MS. The highest contribution to ecological risk belonged to Cd (49 %) based on the PERI index. The Tessier procedure showed that with increasing contamination, exchangeable and carbonate fractions of Cd, Pb, Ni, Zn, and Cu increased by 25 %, 18 %, 17 %, 10 %, and 9 %, respectively. Cadmium and Pb have a high risk of release according to mobility factor (30 < MF < 50) and individual contamination factor (3 < ICF < 6) indices. Cluster analysis revealed that Al-Fe-Co-V-Mn-Cu-Pb derived from lithogenic resources, while As-Cd-Ni-Zn-Cr originated from anthropogenic sources. The adsorption of Co, Ni, V, and Zn to sediments was strongly influenced by Eh/pH, DOC/temperature, and salinity (r > 0.79, r < −0.78, and r < −0.69; p < 0.01).

Characterization and chemical fractionation of potentially toxic elements in soils of a pre-mining mineralized area; an evaluation of mobility and environmental risk.

The environmental geochemical characterization of mineralized areas prior to mining does not receive adequate attention. This study shows trace element distribution in soils of two unexploited porphyry copper deposits located in Darreh-Zereshk and Ali-Abad in central Iran. The study was carried out using a compositional data analysis (CoDa) approach and combination of multivariate statistics and clustering techniques, which made it possible to identify the geochemical associations representing the different areas of the mineral deposits. The results of the chemical analyses, performed by ICP-MS, revealed high concentrations of those elements typically associated with porphyry deposits (As, Co, Cu, Mo, Ni, Pb, and Zn). The typical zonal pattern with an anomaly of Cu in central parts of the system and the prevalence of epithermal elements (Ag, Cd, Pb, and Zn) toward the peripheral propylitic alteration zone were recognized. The XRD analysis of selected soil samples allowed us to determine the distribution of elements within the different carrier minerals. Afterward, geochemical speciation patterns were investigated by a four-step sequential extraction procedure based on BCR protocol. The residual fraction consisting of primary resistant minerals was found to be the main host for As (73-93.4%), Cr (65.1-79.6%), Cu (54.3-81.4%), Ni (58.9-80.6%), V (75.9-88%), and Zn (56.5-60.5%) in the studied soils. Even though these elements are not readily leachable, their behavior and distribution could be largely affected by the mining operation and consequent changes in the physicochemical properties of the soil. The soluble-exchangeable phase was only less than 15% of the total extractions for all elements, except for Cd. With respect to the mobility factor (MF), Cd was the most mobile element followed by Sb and Pb. The measured risk assessment code (RAC) presented the following risk order: Cd > Sb > Ni > Co > Pb > Cr > As > Zn > Cu > V. This study reveals that the acquisition of pre-mining geo-environmental data of trace elements is very important to establish pre-mining backgrounds and baselines for evaluating post-mining or post-reclamation geochemical signatures.

Facilitators and barriers of preventive behaviors against COVID-19 during Ramadan: A phenomenology of Indonesian adults.

Intercity mobility restriction, physical distancing, and mask-wearing are preventive behaviors to reduce the transmission of COVID-19. However, strong cultural and religious traditions become particular challenges in Indonesia. This study uses the Behavior Change Wheel to explore barriers and facilitators for intercity mobility restriction, physical distancing, and mask-wearing during Ramadan. Semi-structured in-depth interviews with 50 Indonesian adults were conducted between 10 April and 4 June 2020. Having mapped codes into the Capacity, Opportunity, Motivation - Behavior (COM-B), and Theoretical Domain Framework (TDF) model, we conducted summative content analysis to analyze the most identified factors to preventive behaviors and proposed interventions to address those factors. Belief about the consequence of preventive behaviors was the most mentioned facilitator to all preventive behaviors among compliers. However, optimism as a TDF factor was commonly mentioned as a barrier to preventive behaviors among non-compliers, while environmental context and resources were the most commonly mentioned factors for intercity mobility restriction. Public health intervention should be implemented considering the persuasion and involvement of religious and local leaders. Concerning job and economic context, policy related to the intercity mobility restriction should be reconsidered to prevent a counterproductive effect.

Risk factors of limited joint mobility in type 1 diabetic adolescents: a two-center experience in Iraq

BACKGROUND Limited joint mobility (LJM) is the most common joint-related complications in patients with diabetes mellitus (DM) and indicates the presence of microvascular complications. This study aimed to assess the frequency of LJM among adolescents with type 1 DM (T1DM), its risk factors, and the other microangiopathies.&#x0D; METHODS In this cross-sectional study, 75 patients (adolescents between 10 and 17 years old) with T1DM were assessed for hand joint mobility using a prayer sign test. It was carried out from January 15 to June 1, 2022 in Baghdad city, Iraq. The patients’ height, body mass index, blood pressure, glycated hemoglobin, and low-density lipoprotein (LDL) were recorded. Only 44 subjects were screened for diabetic nephropathy and 64 for diabetic retinopathy based on the eligibility criteria by the American Diabetes Association guidelines.&#x0D; RESULTS Mean age was 13.60 (1.85) years, with a mean diabetes duration of 5.61 (2.87) years. LJM was found in 18 patients (24%). It was associated with a longer duration of diabetes (p&lt;0.001), high LDL level (p = 0.012), diabetic nephropathy (p = 0.04), and diabetic retinopathy (p&lt;0.001).&#x0D; CONCLUSIONS The proportion of LJM was high among adolescents with T1DM, especially in those with a long duration of DM. It was associated with high LDL levels and diabetic microangiopathies (nephropathy and retinopathy).

Band Engineering of the Second Phase to Reach High Thermoelectric Performance in Cu2 Se-Based Composite Material.

Hitherto, Cu2 Se incorporated with a dispersed second phase shows extremely low thermal conductivity and excellent thermoelectric properties. However, the significant mismatch in electronic band structure between the second phases and the matrix often causes a deterioration of carrier mobility. In this work, based on density functional theory (DFT) calculations, the electronic band structure of the second phase is adjusted through doping S and Te. It is found that Cu2 Se0.88 S0.06 Te0.06 has a highly similar electronic band structure to the Cu2 Se matrix, which results in high carrier mobility and power factor in Cu2 Se-based composite materials. Additionally, the dispersed second-phase Cu2 Se0.88 S0.06 Te0.06 , dislocations, and nanograins are observed in the Cu2 Se/5 wt% Cu2 Se0.88 S0.06 Te0.06 product, which leads to a substantial reduction in the thermal conductivity. Finally, high figure of merit (zT) values of 2.04 (by Dulong-Petit heat capacity) and 2.34 (by Differential Scanning Calorimetry (DSC) measured heat capacity) are achieved at 850 K, which are about 65% higher than that of Cu2 Se in this work and comparable to the recently reported p-type Cu2 Se with outstanding performance.

Genomic diversity of non-diarrheagenic fecal Escherichia coli from children in sub-Saharan Africa and south Asia and their relatedness to diarrheagenic E. coli

Escherichia coli is a frequent member of the healthy human gastrointestinal microbiota, as well as an important human pathogen. Previous studies have focused on the genomic diversity of the pathogenic E. coli and much remains unknown about the non-diarrheagenic E. coli residing in the human gut, particularly among young children in low and middle income countries. Also, gaining additional insight into non-diarrheagenic E. coli is important for understanding gut health as non-diarrheagenic E. coli can prevent infection by diarrheagenic bacteria. In this study we examine the genomic diversity of non-diarrheagenic fecal E. coli from male and female children with or without diarrhea from countries in sub-Saharan Africa and south Asia as part of the Global Enteric Multicenter Study (GEMS). We find that these E. coli exhibit considerable genetic diversity as they were identified in all E. coli phylogroups and an Escherichia cryptic clade. Although these fecal E. coli lack the characteristic virulence factors of diarrheagenic E. coli pathotypes, many exhibit remarkable genomic similarity to previously described diarrheagenic isolates with differences attributed to mobile elements. This raises an important question of whether these non-diarrheagenic fecal E. coli may have at one time possessed the mobile element-encoded virulence factors of diarrheagenic pathotypes or may have the potential to acquire these virulence factors.

The Transport phenomena in CdTe:Cl and CdTe:Cu - calculation from the first principles

In the presented article the method of determining the energy spectrum, the wave function of the charge carrier and the crystal potential in CdTe at an arbitrarily given temperature is considered. Using this approach within the framework of the supercell method the temperature dependences of the ionization energies of various types of defects caused by the introduction of chlorine and copper impurities in cadmium telluride are calculated. Also the offered method allows to define the temperature dependence of the optical and acoustic deformation potentials and as well as the dependence on the temperature the charge carrier’s scattering parameters on ionized impurities, polar optical, piezooptic and piezoacoustic phonons. Within the framework of short-range scattering models the temperature dependences of the charge carrier’s mobility and Hall factor are considered.

Adverse selection and health insurance decisions of young migrant workers: An empirical study in China.

Using data from the China Migrants Dynamic Survey (CMDS) in 2017, this study assessed adverse selection and the impact of mobility factors on adverse selection by analyzing two samples of young migrant workers. The results of the sample analysis showed that young migrant workers with higher health risks were more inclined to enroll in health insurance, indicating the presence of adverse selection. Mobility distance and settle intention have a heterogeneous effect on adverse selection, with young workers who migrate inter-provincially and intend to settle down being more susceptible. The analysis of the insured samples showed that the phenomenon of adverse selection was also evident in the choice of health insurance, with individuals with higher risks preferring Urban Employee Basic Medical Insurance (UEBMI), which has better financial coverage and benefits compared to Rural Residents' Basic Medical Insurance (URRBMI). The heterogeneity test confirmed that mobility distance plays a role in determining the likelihood of adverse selection, with inter-city and inter-province young migrant workers being more likely to show adverse selection.

Rotational dynamics of a neutrally buoyant prolate spheroid in viscoelastic shear flows at finite Reynolds numbers

Non-spherical particles exhibit peculiar behaviour in non-Newtonian flows. In this paper, we numerically investigate the dynamics of a neutrally buoyant prolate spheroid immersed in viscoelastic shear flows at finite Reynolds numbers by means of the immersed boundary method. Our results show that the period of particle rotation changes monotonically with the solvent viscosity ratio but non-monotonically with the mobility factor. Furthermore, we find five rotation modes of the spheroid under the effects of fluid inertia and fluid rheology in the present flow configuration. With weak fluid inertia, the particle rotation rate is remarkably reduced by fluid elasticity, which also induces asymmetric rotational behaviour. While the particle tends to tumble in the shear plane with weak fluid elasticity and moderate fluid inertia. However, as the fluid elasticity increases, the particle rotates with a newly observed mode, named the asymmetric-kayaking mode, which is classified by two additional critical elastic numbers that differ from the earlier studies on Stokesian viscoelastic shear flows. The present findings imply the importance of fluid inertia and fluid elasticity on the particle dynamics and could be potentially used to control the particle orientations in viscoelastic fluid flows.

Effects of Exercise Training on Cognitive Function in Individuals with Heart Failure: A Meta-Analysis.

Cognitive function is critical for disease self-management; however, it is poorer in individuals with heart failure (HF) than in age-matched people who are healthy. Aging and disease progression collectively threaten the cognitive function of individuals with HF. Exercise has been shown to improve the mobility and mortality risk factors of this population, but the effects of exercise on the cognitive function of individuals with HF are unclear. This meta-analysis aimed to examine these potential effects. A systematic literature search was conducted in PubMed, MEDLINE, CINAHL, Cochrane Library, PEDro, and ClinicalKey on literature published until January 2022. Studies examining the effects of exercise training on cognitive function in individuals with HF were included. Characteristics of participants and details of interventions were extracted. Effects of exercise training on global cognitive function, attention, and executive function were analyzed using the Comprehensive Meta-Analysis software. Six studies were included. Individuals with chronic HF were examined in most studies. The average ejection fraction of participants was 23% to 46%. Aerobic exercise was used in most studies. All included studies had exercise frequency of 2 to 3 times per week and a duration of 30 to 60minutes per session for 12 to 18weeks. Compared with the control group, exercise training benefited the global cognitive function of individuals with HF and cognitive impairments (standardized mean difference = 0.44; 95% CI = 0.01 to 0.87). The attention of individuals with HF improved after exercise training compared to that before the intervention. Exercise may improve cognitive function in individuals with HF and cognitive impairments. However, due to large heterogeneity in the study design, more studies are needed to support clinical application. These findings should raise clinicians' awareness about the role of exercise on the cognitive function of individuals with HF, in addition to benefits in physical domains.

Removal of Antibiotic Resistance Genes from Animal Wastewater by Ecological Treatment Technology Based on Plant Absorption.

With the aim of controlling the pollution of antibiotic resistance genes (ARGs) in livestock and poultry wastewater, this paper highlights an ecological treatment technology based on plant absorption and comprehensively discusses the removal effect, driving factors, removal mechanism, and distribution characteristics of ARGs in plant tissues. The review shows that ecological treatment technology based on plant absorption has gradually become an important method of wastewater treatment of livestock and poultry breeding and has a good ARG removal effect. In plant treatment ecosystems, microbial community structure is the main driver of ARGs, while mobile genetic elements, other pollutants, and environmental factors also affect the growth and decline of ARGs. The role of plant uptake and adsorption of matrix particles, which provide attachment sites for microorganisms and contaminants, cannot be ignored. The distribution characteristics of ARGs in different plant tissues were clarified and their transfer mechanism was determined. In conclusion, the main driving factors affecting ARGs in the ecological treatment technology of plant absorption should be grasped, and the removal mechanism of ARGs by root adsorption, rhizosphere microorganisms, and root exudates should be deeply explored, which will be the focus of future research.