Facial Skin Of Patients Research Articles

Temperature regulates bacterial protein production: possible role in rosacea

Facial skin temperature is higher for patients with rosacea. Papules and pustules might arise because bacteria behave differently at these warmer temperatures. We sought to: (1) compare bacteria from facial skin of patients with rosacea with that of control subjects; and (2) grow these bacteria at 30°C and 37°C to compare growth curves and secreted proteins. Bacteria isolated from pustules/skin surfaces of patients with rosacea and skin surfaces of control subjects were identified and cultured at 37°C and 30°C. Secreted proteins were separated by electrophoresis. We found that Staphylococcus epidermidis isolated from patients with rosacea was consistently β-hemolytic, whereas that from control subjects were nonhemolytic. Bacteria from patients with rosacea grew at the same rate and to the same stationary phase whether cultured at 37°C or 30°C. Isolates from patients with rosacea secreted more proteins, and generally more of each protein at 37°C compared with 30°C. In conclusion, bacteria isolated from patients with rosacea secrete different proteins and different amounts of protein at different temperatures.

Prevalence of HPV 7 papillomas in the oral mucosa and facial skin of patients with human immunodeficiency virus

To the Editor.— The majority of human papillomaviruses isolated from cutaneous lesions have been associated with papillomatous lesions in epidermodysplasia verruciformis. Development of benign and malignant lesions containing specific viruses, eg, human papillomaviruses 5,8, and 9, and related human papillomaviruses, were reported to be correlated with the failure of cell-mediated immune functions as cause of this disease. 1 The extensive verrucosis found in renal transplant patients also seems to be a common complication caused by therapeutic immunosuppression. Here human papillomaviruses 5 and 8 are found in premalignant and malignant cutaneous lesions, similar to that seen in patients with epidermodysplasia verruciformis. 2 The presence of these viruses has, however, not been described in any patient with normal immune status. Human papillomavirus 7 is a papillomavirus associated with warts of patients who are butchers and meat handlers. 3 These warts tend to disappear if these individuals cease to practice this occupation (S.

Prevalence of HPV 7 Papillomas in the Oral Mucosa and Facial Skin of Patients With Human Immunodeficiency Virus

<h3>To the Editor.—</h3> The majority of human papillomaviruses isolated from cutaneous lesions have been associated with papillomatous lesions in epidermodysplasia verruciformis. Development of benign and malignant lesions containing specific viruses, eg, human papillomaviruses 5,8, and 9, and related human papillomaviruses, were reported to be correlated with the failure of cell-mediated immune functions as cause of this disease.¹The extensive verrucosis found in renal transplant patients also seems to be a common complication caused by therapeutic immunosuppression. Here human papillomaviruses 5 and 8 are found in premalignant and malignant cutaneous lesions, similar to that seen in patients with epidermodysplasia verruciformis.²The presence of these viruses has, however, not been described in any patient with normal immune status. Human papillomavirus 7 is a papillomavirus associated with warts of patients who are butchers and meat handlers.³These warts tend to disappear if these individuals cease to practice this occupation (S.