Cellulitis Research Articles

Dissecting cellulitis of the scalp treated with adalimumab

Dissecting cellulitis of the scalp treated with adalimumab

Cervical necrotizing fasciitis.

Necrotizing fasciitis (NF) is a rapidly progressing soft tissue infection that carries a significant mortality rate despite intensive treatment. Terms such as hospital gangrene, streptococcal gangrene, Meleney gangrene, gangrenous erysipelas, necrotizing erysipelas ,a ndsynergistic necrotizing cellulitis have been used as synonyms. More commonly seen in the abdomen, perineum, and lower extremities, the neck, owing to its rich vascular network, is a rare site for this fulminant condition. It is characterized by widespread destruction of the subcutaneous tissues and fasciae and gas formation in anatomic spaces. Overlying skin and muscles are spared initially but may undergo necrosis with disease progression. Cervical NF is most commonly caused by dental infection, especially from the mandibular molars, followed by trauma. 1,2 Less common causes of cervical NF are peritonsillar abscess, insect bites, osteoradionecrosis, and hypodermic needle infection. 3 NF can be caused by a single organism but usually occurs as a polymicrobial infection. Among causative bacteriae are group A b-hemolytic and other types of streptococci, Staphylococcus aureus, Eschericihia coli, Klebsiella spp, and some obligate anaerobes, such as Bacteriodes spp and Peptostreptococcus spp 1,4 In this article, three cases of cervical NF are described and the clinical features and management of this fulminant disease are discussed.

Suspensão ao músculo frontal com politetrafluoretileno para o tratamento da blefaroptose

To evaluate the functional results and complications of the use of expanded polytetrafluoroethylene in frontalis suspension surgery for the treatment of blepharoptosis.Frontalis suspension procedure with polytetrafluoroethylene was performed between 2003 and 2007 on 23 patients (36 eyes) with blepharoptosis. An average follow-up time was 15.8 months (range, 3 to 36). Surgical technique used was described by Fox.The causes of blepharoptosis found were: congenital in 20 patients (86.95%), blepharophimosis in 2 (8.69%) and traumatic in 1 (4.35%). At the first week of postoperatory 6 (26.08%) patients related palpebral asymmetry, 4 (17.39%) noticed local edema, 3 (13.04%) presented granulomas and 1 (4.35%) presented facial cellulitis on the ipsilateral frontal region. After 3 months of follow-up 3 (13.04%) patients related palpebral asymmetry and 1 (4.35%) persisted the granuloma.Polytetrafluoroethylene - Model CV3, 6.0 (Gore-tex(R), W.L. Gore & Associates Inc, Flagstaff, AZ, EUA) is an adequate material with good functional results (86.9%), relatively few complications (4.35%) and insatisfaction (13.4%) that could be an alternative for fascia lata in the surgery of frontalis suspension for the treatment of blepharoptosis.

Research and Observation about Incidence and Clinical Aspects of Tarsal Cellulites in Dairy Cows

The present study proposes a presentation of tarsal cellulites incidence in a dairy cows farm, Holstein breed. In this purpose they have been monitoring 160 dairy cows from a farm specialized in milk production, for a period of one year. To appreciate the disease incidence and diagnostic, we used clinical examination, radiological exam and morphometric mensuration , all repeated in short time interval. After the clinical exam and registration of the casuistry, all cases have been classified into a diagnostic score model (created and elaborated by us) with four severity degree, grad 1 represents the easiest modifications and grad 4 represents the most grave. From 160 dairy cows exanimate, in 17 cows (11%) we find tarsal cellulites in different stages: 5 cows with first degree cellulites, 4 cows with second degree cellulites , 4 cows with third degree and 4 cows with fourth degree tarsal cellulites. For morphometric mensuration and appreciation of tarsal region circumference we used a riband with measurement unites in cm that was applied over the affected region, orientated parallel with the floor. Radiological exam made in 9 illness cows, didn’t show any bone modification .in chronic cases, inside the derma structure appears a rich collagen layer who became an impediment for the body healing because he get late the medicaments treatments results.

Is It Really an Atheroma? A Rare Presentation of Maxillary Apical Abscess on the Upper Nasolabial Fold Region

An apical abscess is a dental abscess that occurs at the end of a root, caused by tooth decay which invades the pulp chamber of the tooth. This infection may spread to the adjacent area with clinical presentation of local abscess, facial cellulitis, suppurative osteomyelitis of the jaws, neck infection, or mediastinitis. They are mostly resulted from the mandibular teeth. We reported a rare case of maxillary apical abscess with the clinical presentation of an atheroma-like recurrent facial tumor over upper nasolabial fold region. A 72-year-old lady diagnosed of a recurrent facial atheroma after surgery twice was referred to us. The third time of tumor excision was performed with the result of poor wound healing. A continuous cutaneous draining sinus developed without any improvement. The pathological examination revealed granulomatous tissue with abscess formation. Tracing to the history, she didn't have any dental discomfort recently but a decayed right maxillary canine was noted in the physical examination. The radiography showed periapical radiolucency around the root. An apical abscess was impressed. After extraction of the tooth, the drainage sinus healed spontaneously. A maxillary apical abscess with the clinical presentation of an atheromalike facial tumor on upper nasolabial area was rare. It may be misdiagnosed and treated inappropriately. The surgeons should keep alert the possibility of a dental origin when facing to a chronic, unhealing facial wound after tumor excision.

Facial Cellulitis Induced in Chickens by Mycoplasma gallisepticum Bacterin and Its Treatment

Ten-to-14-day-old replacement chickens were vaccinated subcutaneously in the neck with a Mycoplasma gallisepticum bacterin. A few days later, 40% of the flock developed cellulitis of the head. Birds were submitted for diagnostic investigation between 4 and 6 wk of age. Histology revealed lesions in the subcutis consistent with oil-emulsified vaccine/bacterin reaction. No significant bacteria were isolated from the lesions. Birds were treated with 1 mg of methyl prednisol acetate intramuscularly. Improvement was noted as early as 12 hr posttreatment. One week after treatment only 1%-2% of the flock still had facial cellulitis.

Quality‐initiated prophylactic antibiotic use in laparoscopic‐assisted vaginal hysterectomy

An evidence-based initiation of quality improvement activity for reducing the usage of prophylactic antibiotic in laparoscopic-assisted vaginal hysterectomy (LAVH) in a tertiary hospital. The authors investigated whether single or multiple doses of cefazoline were more cost-effective in preventing postoperative infection associated with LAVH. The study groups comprised of 310 patients who had undergone LAVH continuously in a medical centre. Patients were divided into two groups on the basis of whether they received a single dose or multiple doses (range: two to four doses) of cefazoline during the perioperative period. Postoperative infections such as pelvic cellulitis or abscess, vaginal cuff abscess, wound infection and urinary tract infection that occurred either during hospitalisation or within one month after discharge were observed and recorded. Incremental cost-effectiveness ratio (ICER) was calculated using the mean direct drug cost and the prophylactic effect of infection in both groups. The prophylactic effect of infection was similar in the single-dose group and the multiple-dose group (94.6% vs 93.9%, P = 0.986). The ICER was significantly lower in the single-dose group (153.3 vs 460.4, P < 0.001). The result revealed that a single dose of cefazoline is more cost-effective than multiple doses in the prevention of infection associated with LAVH. It fulfils the goal of cost minimisation and quality of care in today's environment of medical cost containment.

Facial Cellulitis Induced In Chickens By Mycoplasma gallisepticum Bacterin and Its Treatment

Facial Cellulitis Induced In Chickens By Mycoplasma gallisepticum Bacterin and Its Treatment

Analysis the epidemiology and clinical feature of plague cases from 1981 to 2006 year in China

Objective To summarize the epidemiological feature of plague cases oceuwed in China.Methods The epidemiological and clinical data from 1981 to 2006 year in China were analyzed with descriptive study method.Result Nine hundred and seveneteen human plague cases were diagnosed in 9 provinces(regions) from 1981 to 2006 years,105 cases died,the mortality rate being 11.45%,and they distributed in 69 counties (cities or banners).In Qinghai Province 108 cases were diagnosed,the mortality rate was 46.30%(50/108),the cases distributed in 17 counties(cities);137 cans in Guizhou,distributing in 2 counties(cities);517 cases in Yunnan,distributing in 26 counties(cities).Plague cases peaked separately in 1983,1990,1996 and 2000 years,they were 25,75,98 and 254 separately.The principal spreading ways were breathing flying particles,touching,skinning and eating marmot in Qinghai;750 cases were of bubonic plague,among whom 4 cases in Tibet died,the fatality rate was 0.53(4/750);121 cases were of pneumonic prague,among whom 65 cases died,was accounting for 53.72%(65/121);31 cases were of septieaemic plague,and 30 cases died(one cases was cured in Inner Mongolia),accounting for 96.77%(30/31).Others were brain plague,intestinal plague,tonsil plague and plague cellulites,which were cured.Conclusion From 1990,human plague epidemical scope and intensity is enlarging continuously compared with 1980-1990 and there is a trend of going up gradually in China. Key words: Plague; Epidemiology; Analysis

Modern artificial hair implantation: a pilot study of 10 patients

Androgenetic alopecia is an intriguing problem with significant psychological sequelae. Follicular unit transplantation is unsatisfactory in donor depleted cases and artificial hair implantation has historically been marred by poor quality fiber, untrained operators, and inadequate techniques. This paper aims to establish safety and efficacy of a new artificial copolyamide fiber implantation in androgenetic alopecia. Ten healthy adults with androgenetic alopecia who had failed prior conventional therapies were implanted with copolyamide fiber and were followed for a minimum of 3 years. Implantation consisted of 100 test fibers followed by subsequent sessions of up to 500 fibers every 4-6 weeks to achieve a density of 20-40 fibers per cm(2). Implantation techniques and follow-ups maintained a strict adherence to schedule. A total of 10,000 fibers were implanted with a mean of 1000 fibers per patient. With the exception of one patient, implantation was found to be safe, aesthetically pleasing, and psychologically rewarding to its recipients. Sebum deposition and temporary pitting at entry point of most fibers were universal. Recurrent mild folliculitis occurred in 30% of patients. Facial swelling, cellulitis, and severe scarring were absent. Annual fiber fall rate was 15-20%. Choice of fiber, implantation technique, and mandatory follow-up were deemed to be some of the important contributory factors towards our positive results.

Immunization againstHaemophilus influenzaeType B Fails to Prevent Orbital and Facial Cellulitis: Results of a 25-Year Study among Military Children

Vaccines against Haemophilus influenzae type B (HI) and Streptococcus pneumoniae (SP) have dramatically reduced the incidence of bacterial meningitis (due to both HI and SP) and epiglottitis (due to HI) in childhood. The effects of these vaccines on other conditions, however, are less clear. We report an analysis of the effect of serial deployment of various HI and SP vaccines over a 25-year period, involving an examination of over half a million pediatric hospitalizations occurring in Army hospitals worldwide. We show that, in marked contrast to the reduction in the number of meningitis and epiglottitis cases, the disease burden of orbital and facial cellulitis--conditions oft attributed to HI and SP-did not diminish.

Managing cellulitis and impetigo

Managing cellulitis and impetigo

Subcutaneous cellulitis of the thigh due to grass awn migration in a German shepherd dog

Cellulitis is a severe, deep, suppurative infection that is poorly defined and tends to dissect through tissue planes. When a foreign body enters the body, white blood cells attack the site and fight the invading agent. Sometimes, this collection of blood cells forms a packed of pus or an abscess within the body’s tissues, organs, or confined spaces. Chronic sinus tracks have been reported previously in the lumbar, paralumbar, and flank skin area in hunting dogs with grass awn and other migrating foreign bodies. Surprisingly, little information is published on histopathological changes about grass awn migration subcutaneously. This report describes histopathological characteristics of subcutaneous cellulitis of the thigh due to grass awn migration in a German shepherd dog.

Safety of Trans Vaginal Mesh procedure: Retrospective study of 684 patients

To study peri-surgical complications after cure of genital prolapse by vaginal route using interposition of synthetic prostheses Gynemesh Prolene Soft (Gynecare) following the Trans Vaginal Mesh (TVM) technique. The present retrospective multicentered study comprised 684 patients who underwent surgery at seven French centers between October 2002 and December 2004. All patients had a genital prolapse >or=3 (C3/H3/E3/R3) according to International continence society (ICS) classification. According to each case, prosthetic interposition was total, or anterior only or posterior only. Patients were systematically seen 6 weeks, 3 months and 6 months after surgery. Multivaried statistical analysis followed a model of logistic regression applied to each post-surgical complication. The mean age of patients was 63.5 years (30-94). The mean follow-up period was 3.6 months. 84.3% of patients were post-menopause, 24.3% had hysterectomy, 16.7% previous cure of prolapse, and 11.1% cure of stress urinary incontinence (SUI). During the procedure, hysterectomy was combined in 50.3% of cases, cervix amputation in 1.5%, and cure of SUI in 40.9%. 15.8% were treated for a cystocele only. 14.8% had only a rectocele +/- elytrocele and 69.4% had a prolapse touching both compartments, anterior and posterior. In peri-surgical complications, (2%) were five bladder wounds (0.7%), one rectal wound (0.15%) and seven hemorrhages greater that 200 mL (1%). Among early post-surgical complications (during the first month after surgery) (2.8%) were two pelvic abscesses (0.29%), 13 pelvic hematomas (1.9%), one pelvic cellulitis (0.15%), two vesicovaginal fistulas and one rectovaginal fistula (0.15%). Among late post-surgical complications (33.6%) there were 77 granulomas or prosthetic expositions (11.3% [6.7% in the vaginal anterior wall, 2.1% in the vaginal posterior wall and 4.8% in the fornix]), 80 prosthetic retractions (11.7%), 36 relapse of prolapse (6.9%) and 37 SUI de novo (5.4%). Multivaried analysis shows that previous history of hysterectomy or placing of an isolated anterior prosthesis increase the risk of peri-surgical complication; preserved uterus and isolated posterior prosthesis lessen the risk of granulomas and prosthetic retractions; and association of a Richter's intervention increases the rate of prosthetic retractions. Cure of genital prolapse with synthetic prostheses interposed by vaginal route is now reliable and can be reproduced with a low rate of peri- and early post-surgical complications. However, our study shows a certain number of late post-surgical complications after insertion of strengthening synthetic vaginal implants (prosthetic expositions and prosthetic retractions). These retrospective results will soon be compared to a prospective study.

Cellulitis Outcome Best in Hospital-Admitted Kids

Cellulitis Outcome Best in Hospital-Admitted Kids

Clindamycin-resistant Clostridium perfringens cellulitis

Clostridium perfringens is responsible for a number of clinical conditions ranging from relatively mild food poisoning to the potentially life-threatening gas gangrene. Fortunately, C. perfringens has remained relatively susceptible to first line antibiotics in the treatment of soft tissue infection, however, the prevalence of antibiotic resistance is increasing amongst other anaerobic organisms. A case of anaerobic cellulitis caused by a clindamycin-resistant C. perfringens is described here, emphasising the emerging problem of antimicrobial resistance.

Scurvy masquerading as infectious cellulites

Internal Medicine JournalVolume 38, Issue 6a p. 452-453 Scurvy masquerading as infectious cellulites Correction(s) for this article Erratum Volume 38Issue 8Internal Medicine Journal pages: 676-676 First Published online: September 3, 2008 E Patrozou, E Patrozou Memorial Hospital of Rhode Island/Brown University Department of Internal Medicine/Division of Infectious Diseases Pawtucket, RI, USASearch for more papers by this authorS Opal, S Opal Memorial Hospital of Rhode Island/Brown University Department of Internal Medicine/Division of Infectious Diseases Pawtucket, RI, USASearch for more papers by this author E Patrozou, E Patrozou Memorial Hospital of Rhode Island/Brown University Department of Internal Medicine/Division of Infectious Diseases Pawtucket, RI, USASearch for more papers by this authorS Opal, S Opal Memorial Hospital of Rhode Island/Brown University Department of Internal Medicine/Division of Infectious Diseases Pawtucket, RI, USASearch for more papers by this author First published: 28 June 2008 https://doi.org/10.1111/j.1445-5994.2008.01662.xCitations: 4Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat No abstract is available for this article.Citing Literature Volume38, Issue6aJune 2008Pages 452-453 RelatedInformation

Tumor-Associated Hypercalcemia in a Patient with Paget's Disease

Paget's disease of the bone, which is characterized by a focal region of highly exaggerated bone remodeling, is very rare in Asia. Most patients with Paget's disease are asymptomatic; they are normocalcemic and show elevated alkaline phosphatase levels. Hypercalcemia in patients with Paget's disease has rarely been reported. We report one Chinese patient with Paget's disease involving the maxilla bone with an initial presentation of facial cellulitis. Asymptomatic hypercalcemia with a low-normal intact parathyroid hormone level developed 9 years later. After clodronate treatment, the level of alkaline phosphatase normalized, but the hypercalcemia did not respond adequately. After analysis of tumor markers and imaging studies, a clinical diagnosis of pancreatic adenocarcinoma with multiple hepatic and lung metastases with pleural effusion was made. We suggest that malignancy-associated hypercalcemia should be considered as one of the causes of hypercalcemia in patients with Paget's disease.

E. coli Traffic Patterns Suggest Routine Household Transmission

Research suggests that bacterial infections such as Staphylococcus aureus cellulitis and Escherichia coli cystitis might actually be sexually transmitted, as high risk for colonization and infection with these pathogenic strains is repeatedly found in sexual partners of infected patients. Little is known, however, about overall household patterns of acquiring and transmitting these common bacteria. Minnesota researchers used genomic …

TMP/SMX and Rifampin for Abscess-associated Cellulitis

TMP/SMX and Rifampin for Abscess-associated Cellulitis