Eye Pupil Size Research Articles

Near eye display based on multiplexed retinal projections for robust compensation of eye pupil variance.

Among various specifications of near eye display (NED) devices, a compact formfactor is essential for comfortable user experience but also the hardest one to accomplish due to the slowest progresses. A pinhole/pinlight array based light-field (LF) technique is considered as one of the candidates to achieve that goal without thicker and heavier refractive optics. Despite those promising advantages, however, there are critical issues, such as dark spots and contrast distortion, which degrade the image quality because of the vulnerability of the LF retinal image when the observer's eye pupil size changes. Regardless of previous attempts to overcome those artifacts, it was impossible to resolve both issues due to their trade-off relation. In this paper, in order to resolve them simultaneously, we propose a concept of multiplexed retinal projections to integrate the LF retinal image through rotating transitions of refined and modulated elemental images for robust compensation of eye pupil variance with improved conservation of contrast distribution. Experimental demonstrations and quantitative analysis are also provided to verify the principle.

Pupil-Aware Holography

Holographic displays promise to deliver unprecedented display capabilities in augmented reality applications, featuring a wide field of view, wide color gamut, spatial resolution, and depth cues all in a compact form factor. While emerging holographic display approaches have been successful in achieving large étendue and high image quality as seen by a camera, the large étendue also reveals a problem that makes existing displays impractical: the sampling of the holographic field by the eye pupil. Existing methods have not investigated this issue due to the lack of displays with large enough étendue, and, as such, they suffer from severe artifacts with varying eye pupil size and location. We show that the holographic field as sampled by the eye pupil is highly varying for existing display setups, and we propose pupil-aware holography that maximizes the perceptual image quality irrespective of the size, location, and orientation of the eye pupil in a near-eye holographic display. We validate the proposed approach both in simulations and on a prototype holographic display and show that our method eliminates severe artifacts and significantly outperforms existing approaches.

Photographic Depiction of the Field of View with Spectacles-mounted Low Vision Aids.

Photographic depiction helps to illustrate the primary and secondary field of view effects of low vision devices along with their utility to clinicians, patients, and caretakers. This technique may also be helpful for designers and researchers in improving the design and fitting of low vision devices. The field of view through spectacles-mounted low vision devices has typically been evaluated using perimetry. However, the perimetric field diagram is different from the retinal image and often fails to represent the important aspects of the field of view and visual parameters. We developed a photographic depiction method to record and veridically show the field of view effects of these devices. We used a 3D-printed holder to place spectacles-mounted devices at the same distance from the empirically determined reference point of the field of view in a camera lens (f = 16 mm) as they would be from an eye, when in use. The field of view effects of a bioptic telescope, a minifier (reverse telescope), and peripheral prisms were captured using a conventional camera, representing retinal images. The human eye pupil size (adjusting the F number: f/2.8 to f/8 and f/22 in the camera lens) and fitting parameters (pantoscopic tilt and back vertex distance) varied. Real-world indoor and outdoor walking and driving scenarios were depicted as retinal images illustrating the field of view through low vision devices, distinguishing optical and obscuration scotomas, and demonstrating secondary effects (spatial distortions, viewpoint changes, diplopia, spurious reflection, and multiplexing effects) not illustrated by perimetric field diagrams. Photographic depiction illustrates the primary and secondary field of view effects of the low vision devices. These images highlight the benefit and possible trade-offs of the low vision devices and may be beneficial in education and training.

Extending eyebox with tunable viewpoints for see-through near-eye display.

The Maxwellian display presents always-focused images to the viewer, alleviating the vergence-accommodation conflict (VAC) in near-eye displays (NEDs). However, the limited eyebox of the typical Maxwellian display prevents it from wider applications. We propose a Maxwellian see-through NED based on a multiplexed holographic optical element (HOE) and polarization gratings (PGs) to extend the eyebox by viewpoint multiplication. The multiplexed HOE functions as multiple convex lenses to form multiple viewpoints, which are copied to different locations by PGs. To mitigate the imaging problem that multiple viewpoints or no viewpoints enter the eye pupil, the viewpoints can be tuned by mechanically moving a PG. We implement our method in a proof-of-concept system. The optical experiments confirm that the proposed display system provides always in-focus images within a 12 mm eyebox in the horizontal direction with a 32.7° diagonal field of view (FOV) and a 16.5 mm eye relief (ERF), and its viewpoints are tunable to match the actual eye pupil size. Compared with other techniques to extend the eyebox of Maxwellian displays, the proposed method shows competitive performances of a large eyebox, adaptability to the eye pupil size, and focus cues within a large depth range.

Pupil Size and Intelligence: A Large-Scale Replication Study

A recent study by Tsukahara et al. (2016) found correlations between pupil size and measures of intelligence, with r values around .30. We attempted to replicate this association in a large dataset of US military personnel (n = 4,462). General intelligence, g, was extracted from 19 diverse tests. We first confirmed that right and left eye pupil size measures are strongly correlated (r = .97), suggesting high measurement reliability for this phenotype. However, unlike Tsukuhara et al., we could establish only small to nonexistent associations between cognitive ability and pupil size (r’s -.01 to .06, r with g specifically = .05). Regression analyses, controlling for multiple covariates, revealed that the association in this large representative sample was entirely attributable to confounding with race/ethnicity. Mean pupil size (mm) was 3.56, 3.35, and 3.23 for whites, Hispanics, and blacks, respectively. Relative to whites, this corresponds to effect sizes of 0.22 and 0.34 d. It is unclear why our results differ from those reported by Tsukahara et al. (2016), but the ethnic size rank order suggests an evolutionary explanation in terms of geo-bio-climatic selection for pupil size.

A personal visual comfort model: predict individual’s visual comfort using occupant eye pupil size and machine learning

Lighting, as a significant component of indoor environmental quality, was found to be a primary contributor to deficient indoor environments in today’s workplace. This resulted from the fact that current guidelines are derived from empirical values and neglect the prevalence of computer-based tasks in current offices. A personal visual comfort model was designed to predict the degree of an individual’s visual comfort, as a way of evaluating the indoor lighting of the environment. Development of the model relied on experimental data, including individual eye pupil sizes, visual sensations, and visual satisfaction in response to various illuminance levels used for tests of six human subjects. The results showed that (1) A personal comfort model was needed, (2) the personal comfort model produced a median accuracy of 0.7086 for visual sensation and 0.65467 for visual satisfaction for all subjects; (3) To develop a prediction model for the sample group, the Support Vector Machine algorithm, outperformed the Logistic Regression and the Gaussian Naïve Bayes in terms of prediction accuracy. It was concluded that a personal visual comfort model can use a building’s occupant’s eye pupil size to generate an accurate prediction of that occupant’s visual sensations and visual satisfaction that can, therefore, be applied with lighting control to improve the indoor environment and energy use in that building.

Comparing methods for the analysis of pupillary response

Changes in eye-pupil size index a range of cognitive processes. However, variations in the protocols used to analyze such data exist in the psychological literature. This raises the question of whether different approaches to pupillary response data influence the outcome of the analysis. To address this question, four methods of analysis were compared, using pupillary responses to sexually appetitive visual content as example data. These methods comprised analysis of the unadjusted (raw) pupillary response data, z-scored data, percentage-change data, and data transformed by a prestimulus baseline correction. Across two experiments, these methods yielded near-identical outcomes, leading to similar conclusions. This suggests that the range of approaches that are employed in the psychological literature to analyze pupillary response data do not fundamentally influence the outcome of the analysis. However, some systematic carryover effects were observed when a prestimulus baseline correction was applied, whereby dilation effects from an arousing target on one trial still influenced pupil size on the next trial. This indicates that the appropriate application of this analysis might require additional information, such as prior knowledge of the duration of carryover effects.

SpotMetrics: An Open-Source Image-Analysis Software Plugin for Automatic Chromatophore Detection and Measurement.

Coleoid cephalopods (squid, octopus, and sepia) are renowned for their elaborate body patterning capabilities, which are employed for camouflage or communication. The specific chromatic appearance of a cephalopod, at any given moment, is a direct result of the combined action of their intradermal pigmented chromatophore organs and reflecting cells. Therefore, a lot can be learned about the cephalopod coloration system by video recording and analyzing the activation of individual chromatophores in time. The fact that adult cephalopods have small chromatophores, up to several hundred thousand in number, makes measurement and analysis over several seconds a difficult task. However, current advancements in videography enable high-resolution and high framerate recording, which can be used to record chromatophore activity in more detail and accuracy in both space and time domains. In turn, the additional pixel information and extra frames per video from such recordings result in large video files of several gigabytes, even when the recording spans only few minutes. We created a software plugin, “SpotMetrics,” that can automatically analyze high resolution, high framerate video of chromatophore organ activation in time. This image analysis software can track hundreds of individual chromatophores over several hundred frames to provide measurements of size and color. This software may also be used to measure differences in chromatophore activation during different behaviors which will contribute to our understanding of the cephalopod sensorimotor integration system. In addition, this software can potentially be utilized to detect numbers of round objects and size changes in time, such as eye pupil size or number of bacteria in a sample. Thus, we are making this software plugin freely available as open-source because we believe it will be of benefit to other colleagues both in the cephalopod biology field and also within other disciplines.

Performance of binoculars: Berek's model of target detection.

A model of target detection thresholds, first presented by Max Berek of Leitz, is fitted into a simple set of closed equations. These are combined with a recently published universal formula for the human eye's pupil size to yield a versatile formalism that is capable of predicting binocular performance gains. The model encompasses target size, contrast, environmental luminance, binocular's objective diameter, magnification, angle of view, transmission, stray light, and the observer's age. We analyze performance parameters of various common binocular models and compare the results with popular approximations to binocular performance, like the well-known twilight index. The formalisms presented here are of interest in military target detection as well as in civil applications such as hunting, surveillance, object security, law enforcement, and astronomy.

Women's pupillary responses to sexually significant others during the hormonal cycle

Women's sexual preferences can change over the hormonal cycle, as several studies, based on responses to questionnaires, diaries, and ratings of photographs, have indicated increased sexual interests around the time of ovulation. However, fewer studies have measured changes in attention or interest to sexually significant stimuli in terms of physiological responses that are not under voluntary control and measure sexual interest indirectly (i.e., without mention of sexual feelings or activities). In the present study, we indexed changes in sexual interest in terms of changes in the eye pupil's size. Pupillary diameter is known to have a proportional relation to the observer's level of interest and attention to a visual stimulus as well as to physical pleasure. Fourteen women (7 being “pill” users) viewed photos on a computer screen while their pupil diameters were recorded using an infrared eye-tracking device. Three measures were taken for each participant during three time windows that estimated the ovulatory, luteal, and menstrual phase of the cycle. We found an increase in mean pupil diameter for sexually significant stimuli during the fertile phase and this pupillary change was also specific to pictures of the participants' actual sexual partners. Moreover, this effect was only seen for women who did not use oral contraceptives. These findings confirm that women's attention for sexually significant stimuli is higher during their fertile phase of the menstrual cycle, and that changes in sexual interest are implicitly measurable using pupillometry.

Visual axial PSF of diffractive trifocal lenses

The ophthalmic applications of a diffractive trifocal lens design with adjustable add powers and light distribution in the foci are investigated. Axial PSFs of the trifocal lenses are calculated and analyzed as a function of the design parameters and the eye pupil size. The optical performance in actual eyes is also simulated by including the measured ocular wave aberration functions of human eyes in the calculation of transverse and axial PSFs, and Strehl ratio axial variation. The effect of the polychromatic character of natural light has also been considered. The calculus and simulation method of this paper can be applied for the design and analysis of any other kind of diffractive or refractive multifocal contact or intraocular lens.

Diffractive exit-pupil expander for display applications

Two-dimensional binary diffraction gratings can be used in wearable display applications as exit-pupil expanders (EPEs) (or numerical-aperture expanders) to increase the size of the display exit pupil. In retinal scanning displays the EPE is placed at an intermediate image plane between the scanners and the display exit pupil. A focused spot scans across the diffractive EPE and produces multiple diffraction orders at the exit pupil. The overall luminance uniformity across the exit pupil as perceived by the viewer is a function of the uniformity of the diffraction-order intensities, focused-spot size, grating period, scanning-beam profile, and the viewer's eye-pupil size. The design, the diffraction-order uniformity, and the effects of the grating phase angle on the uniformity for binary diffraction gratings are discussed. Also discussed are the display exit-pupil uniformity and the impact of the diffractive EPE on the point-spread function and the modulation transfer function of the display. Both theoretical and experimental results are presented.

Assessment of rates of deformity in wild frog populations using in situ cages: a case study of Leopard Frogs (Rana pipiens) in Ontario, Canada

High rates of deformity in wild amphibian populations from north-eastern North America have been increasingly reported since 1995. In the St Lawrence River basin (Canada) elevated frequencies of limb and eye deformities in mudpuppies (Necturus maculosus) and leopard frogs (Rana pipiens) were recorded in the early 1990s. A caging study was conducted during 1998 to verify the rates recorded in leopard frogs and pursue the potential causes of deformities seen in juveniles and adults. Week-old leopard frog tadpoles were collected from a reference wetland and maintained through to metamorphosis in cages in previously identified high risk wetlands. Deformity frequencies were measured and compared with frequencies measured in wild populations of leopard frogs inhabiting the same wetlands. The results of caging studies and sampling of wild populations were also compared with corresponding data collected from a reference wetland. No deformities were observed in caged or wild reference animals. Very low deformity frequencies (up to 2.2%) were observed in frogs caged in high risk wetlands, but greater frequencies (3.4-10%) were observed in wild young-of-the-year frogs captured at the same sites. The types of deformities were similar among groups; they included fused, missing or extra digits and disproportionate hindlimb length or eye pupil size. In addition, mortality rates were elevated in two cages in high risk wetlands. In general, the caging procedure was effective in establishing the potential for production of deformities in the waters of a given wetland, but tended to underestimate the rates calculated for samples of wild populations. The ramifications of the first-year findings for similar assessments of amphibian deformity rates and establishment of cause-effect linkages are discussed.

Method to estimate the human pupil size from the bandwidth of coherent retinal images

A new technique for extracting information on the size of the pupil of the human eye is presented. It is based on the recording of coherent short-exposure retinal images of a point source after double pass through the ocular media. The eye's pupil size is then estimated by computing the cutoff frequency in the power spectrum of these coherent images, which is related with the average width of the speckle. First the validity of the technique is established by use of an artificial eye, and then results are obtained in the living human eye. This method has the potential of determining the eye's pupil diameter with a standard error of the order of 0.1 mm and can be used in different visual optics experiments, although with its present components it is especially appropriate for experiments based on the recording of coherent retinal images.

Estimation of Human Cognitive State by Psycho-Physiological Data

The estimation method for human cognitive state at man-machine interface was investigated by means of psycho-physiological method. The estimation method is firstly to reduce data patterns seen in the short-time responses of multiple physiological measures, and then to construct discriminate functions which correlate the obtained data patterns with the different kinds of cognitive state. The used physiological measures are eye saccade fraction, eye pupil size, eye blinking rate, skin potential response, heart rate and respiration rate. By using protocol data taken, from a subject during a, cognitive task experiment, three different kinds of discrimination functions were constructed, based on either fuzzy logic method or statistical analysis (quantification method class ?2). The intercomparison of the three functions thus obtained was made with respect to the accuracy for the cognitive state discrimination, along with the general discussion concerning the limitation of the proposed psycho-physiological method and its applicability to personal differences.