Eye Socket Research Articles

Orbital and peri-ocular parffinoma: case series and literature review

BackgroundParaffinoma is a rare and intriguing condition in medicine. In this disorder, an orbital lipogranulomatosis reaction is caused by the penetration of mineral oils (particularly paraffin) into the tissues surrounding the eye.MethodsIn this report, we discuss six cases of paraffinoma affecting the eye socket following sinus surgery. For previous cases literature review, we obtained articles from searching in the PubMed, Scopus, Scholar Google and, Science of Web databases.ResultsAfter the reporting of 6 paraffinoma cases and literature review, the data related to the disease were categorized into the categories of disease definition, differential diagnosis, clinical manifestation, radiological manifestation, and histopathological diagnosis and treatment methods.ConclusionsParaffinoma is a rare and time-delayed diagnosis after various surgeries and therefore may challenge the physician to make the correct diagnosis at first. It is necessary for ophthalmologists to consider this diagnosis in cases of masses around the eyelid and orbit in patients with a history of sinus and nose surgery in other differential diagnoses.

Enhancement of eye socket recognition performance using inverse histogram fusion images and the Gabor transform

AbstractThe eye socket is a cavity in the skull that encloses the eyeball and its surrounding muscles. It has unique shapes in individuals. This study proposes a new recognition method that relies on the eye socket shape and region. This method involves the utilization of an inverse histogram fusion image to generate Gabor features from the identified eye socket regions. These Gabor features are subsequently transformed into Gabor images and employed for recognition by utilizing both traditional methods and deep‐learning models. Four distinct benchmark datasets (Flickr30, BioID, Masked AT & T, and CK+) were used to evaluate the method's performance. These datasets encompass a range of perspectives, including variations in eye shape, covering, and angles. Experimental results and comparative studies indicate that the proposed method achieved a significantly () higher accuracy (average value greater than 92.18%) than that of the relevant identity recognition method and state‐of‐the‐art deep networks (average value less than 78%). We conclude that this improved generalization has significant implications for advancing the methodologies employed for identity recognition.

Traceological features of anthropogenic incisions on Yuka Mammoth’ hide (Yakutia)

The article presents the data of experimental-trasological analysis, confirming the cutting of the Yuka mammoth skin by man in the northeast of Yakutia during of time approximately ca 39,000 – 38,000 BP during relatively warm period (MIS 3). A series of experiments have been conducted to study processing separate hide pieces from different animals including one mammoth individual. It is fundamental to note that for the first time use-wear methods were adapted for the study of soft organic material, namely the mammoth hide which to date has only been available for research in Yakutia.The result was an understanding of the criteria for the difference between the cuts made by stone and metal tools. In the examination we observed and documented a large incision along the Yuka Mammoth’s spinal ridge and incisions around the eye sockets. Traces of anthropogenic cuts on mammoth skin and their distinction from injuries caused by animals were described. Comparison of the experimental data and anthropogenic traces on mammoth Yuka’s carcass has shown that these cutting can have been made only with stone instruments before freezing the mammoth carcass.

Clinical characterization and long-term postoperative outcomes of retinoblastoma patients receiving enucleation and primary orbital implantation in early infancy: an observational study

ObjectivesTo retrospectively investigate clinical characterization and the long-term postoperative outcomes of retinoblastoma (RB) patients receiving enucleation with primary orbital implantation in early infancy (0–6 months old).MethodsThe clinical and follow-up data of 42 RB patients receiving enucleation with primary orbital implantation in early infancy at Beijing Tongren Hospital from December 2009 to January 2020 were analysed. The average follow-up time was 83 months. The patient group included 24 males and 18 females, 30 unilateral and 12 bilateral cases. A total of 44 eyes with 10 in stage D and 34 in stage E underwent 40 unilateral and 2 bilateral surgeries. 17 RB eyes received hydrogel and 27 RB eyes received hydroxyapatite implants. This study was performed by following the guideline of STROBE.ResultsEnucleation combined with primary orbital implantation promoted survival and was safe with few and minor complications such as increased secretion, upper eyelid ptosis, and sunken eye sockets which were not affected by stages, lateralities, or implant materials. 55-80% RB patients exhibited satisfactory appearance and obvious or moderate motility of orbital implants according to the evaluation by doctors and family members. Family members were likely more optimistic about the appearance and more pessimistic about motility of the orbital implantation than doctors did.The quality of life was high as indicated by PedsQL3.0 or PedsQL4.0 scores ( ≧ 90 for > 75% patients). It was not affected by the stages, laterality, and implant materials, nor affected by the appearance and motility of the implants.ConclusionsThe outcomes of the combination of enucleation and primary orbital implantation for pertinent RB patients in early infancy are generally satisfactory with few and minor complications, high safety, appearance, and overall quality of life. Enucleation combined with primary orbital implantation in early infancy benefits pertinent RB patients in appearance, survival, and quality of life.

EDUCATIONAL AND METHODOLOGICAL FUNDAMENTALS OF TEACHING THE TOPIC "ANATOMY OF THE SUPPORTING APPARATUS OF THE EYE"

The article is devoted to the analysis of the peculiarities of teaching the topic "Supporting apparatus of the eye" in domestic medical higher education institutions. Given the importance of studying the anatomy of the connective tissue structures of the eye socket for understanding the spread of infectious processes, we believe that in modern curricula on normal human anatomy, methodologists pay insufficient attention to their study. As a rule, these questions are only a small part of the wide variations of the topic "Accessory structures of the eye". At the same time, the peculiarities of the structure of the periosteum of the eye socket, the orbital septum, the socket of the eyeball, Whitnall's and Lockwood's ligaments, the tendinous funnel, the fascia of the rectus and oblique muscles have an extremely complex structure. Thorough knowledge of these features is a necessary condition for the development of the clinical thinking of the future doctor. The development of modern technologies for the surgical treatment of many eye diseases requires scientists and teachers to improve their knowledge of the structure of certain connective tissue structures of the eye. For example, the features of the structure and attachment of Tenon's capsule in the limbus area are the formation of an area where the approach to the fibrous membrane of the eye during surgical interventions can be carried out without damaging it. Nowadays, aesthetic surgery of the eye area is gaining particular popularity. Blepharoplasty is one of the surgical interventions most often performed in plastic surgery. Without a perfect knowledge of the structure of the orbital septum, safe performance of blepharoplasty is impossible. The surgeon needs to be oriented in the peculiarities of the structure of the orbital septum and the differences in its structure in the areas of the upper and lower eyelids. It is important to note that in the lower part of the eye socket, the space behind the orbital septum is much larger than in the upper part, it sinks into the depth of the eye socket, behind the back pole of the eye and is filled with fatty tissue, the growth of which is often an indication for surgical intervention. The structure of the upper part of the space behind the orbital septum is somewhat more complex, because it contains many vessels, nerves and connective tissue structures.

NFIX gene mutation causes Marshall-Smith syndrome in a pair of identical twins and literature review

This article reports on the clinical and genetic characteristics of monozygotic twins with Marshall-Smith syndrome (MRSHSS) due to a mutation in the NFIX gene, along with a review of related literature. Both patients presented with global developmental delays, a prominent forehead, shallow eye sockets, and pectus excavatum. Genetic testing revealed a heterozygous splicing site mutation c.697+1G>A in both children, with parents showing wild-type at this locus. According to the guidelines of the American College of Medical Genetics and Genomics, this mutation is considered likely pathogenic and has not been previously reported in the literature. A review of the literature identified 32 MRSHSS patients with splicing/frameshift mutations. Accelerated bone maturation and moderate to severe global developmental delay/intellectual disability are the primary clinical manifestations of patients with MRSHSS. Genetic testing results are crucial for the diagnosis of this condition.

3D-Oculography: New Method of Determination of Human Gaze Point Position in Space

INTRODUCTION: Oculography — a method of recording movement of eyeballs of a human or animal by analyzing changes in electrical potentials recorded by two electrodes fixed on skin near the eye socket is used to solve various problems. Among them are the determination of pronounced nystagmus, of characteristic changes of oculomotor reactions in different conditions of observing video images. Of interest is the determination of the position of gaze point (GP) and of the area of increased attention in three-dimensional space. This information is associated with the cognitive system of the observer and is of interest not only to physiologists, but also to specialists of related fields. . AIM: To experimentally prove the effectiveness of the developed method of 3D-oculography providing determination of the GP position in space. MATERIALS AND METHODS: The possibility of restoring GP position based on the analysis of recorded oculograms even in the presence of additive noise induced by the external electromagnetic fields, is proven by the numeric modeling method. Direct experimental studies were conducted with recording oculograms of a human observer on a previously verified equipment. A ZB-2 oculograph was used, the data obtained were verified by the method of average values. RESULTS: The obtained modeling results permitted to determine the maximal values of dispersion of additive noise and amplitude shifts of signals, which make possible satisfactory restoration of the coordinates of the GP and parameters of its movement trajectory. The qualitative correspondence of the experimental results to the results of numerical modeling was proven. The correspondence between trajectories of the observed object moving in space and trajectories of GP movement synthesized from counts of recorded oculograms was confirmed. CONCLUSION: Multichannel record of oculographic signals permits restoring parameters of the GP trajectory. Creating systems for recording these signals requires minimization of the noise level. An increase in dispersion of the noise component of the signal leads to most significant errors in calculating the coordinates of trajectory points.

Correction of severe upper-eyelid sunken deformity in Asians by double-eyelid procedure and combination of orbital fat pad repositioning and autologous fat transplantation: a one-year follow-up study of 79 cases.

Nowadays, people's pace of life continues to rapid up, and many bad habits will accelerate the aging of the eye periphery, and patients with sunken upper eyelids are to be found in younger people. In young Asians, single eyelids are often accompanied by upper eyelid depression, so correcting the upper eyelid depression during blepharoplasty becomes a higher challenge for plastic surgeons. Current surgical methods for upper eyelid depression include three major categories: tissue repositioning, injection and filling, and combined use. According to grades 1 and 2 are mild or moderate upper eyelid sunken. The sunken can be well corrected only by repositioning the orbital fat pad, while the correction effect for severe upper eyelid sunken in grades 3 and 4 is Poor, need to be used in combination to achieve the desired effect. The authors sought to determine whether, for patients with single eyelids and severe upper eyelid depression of grades 3 and 4, combined with orbital fat pad repositioning and autologous fat transplantation during blepharoplasty, an aesthetic and youthful blepharoplasty can be achieved. This study included 79 patients with single eyelids and severe upper eyelid depression of grades 3 and 4 who received treatment between June 2020 and July 2022. All patients underwent double eyelid surgery plus orbital fat repositioning and autologous fat grafting. After a minimum follow-up period of 1 year, overall patient satisfaction was 92%. The recurrence rate within the first year was 6% and the complication rate was 5%. This combined surgery may be an option for young Asians with single eyelids and severe upper eyelid depression. In this study, the surgery resulted in natural-looking double eyelids and younger-looking eye sockets in most patients. A combination of different surgical methods based on the patient's preoperative condition is critical to achieving long-term correction.

Evaluation of clinical effectiveness of hygiene products for the care of facial prostheses

BACKGROUND: Because of the porous structure of the structural material used in the production of facial prostheses, without careful hygienic care, microbial biofilms may form on the material surface, its color and shape may change, and premature aging may occur. Means for the hygienic care of facial prostheses and research to confirm their clinical effectiveness are crucial in dentistry.
 AIM: To increase the effectiveness of the hygienic treatment of facial epitheses.
 METHODS: A single-center randomized study was conducted to assess the clinical effectiveness of hygiene products for the care of facial prostheses. This study involved patients with exenteration of the eye socket, previously prosthetic with adhesive fixation epitheses. The patients were divided into four groups and received different hygienic care methods. Furthermore, during the use of the prosthesis for 14 days and 1 and 3 months, the tissues of the prosthetic bed and hygienic condition of the prosthesis were evaluated, and the quality of life of patients was determined.
 RESULTS: According to the results of measuring the area of inflammation of tissues of the prosthetic bed of the eye socket at different terms, positive dynamics were found in the groups that used the proposed hygiene products.
 CONCLUSION: A strong positive correlation (r 0.9) of the average values of the quality of life index, area of inflammation, and hygiene index of the orbital epitheses in the study groups at the appropriate time indicates improved quality of life of patients who used the proposed hygiene products by reducing the amount of bacterial plaque on the surface of the epithesis and, in turn, reducing the area of inflammatory reactions and increasing comfort in wearing the prosthesis.

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Visual Snow Syndrome in Patient with Migraine: Case Report and Literature Review.

Visual snow syndrome (VSS) is a rarely diagnosed neurological phenomenon. It is a visual disorder characterised by the presence of numerous white, black, or translucent dots in the visual field, resembling the 'snow' of an analogue TV set experiencing reception interference. According to The International Classification of Headache Disorders, 3rd edition, visual snow is defined as a pattern of continuous small dots across the visual field lasting >3 months and accompanied by at least two of the following four additional symptoms: palinopsia, increased entoptic phenomena, photophobia, and nyctalopia. These complaints are not consistent with a typical migraine with visual aura and cannot be better explained by another disorder. The authors present the case of a 39-year-old woman who was diagnosed with VSS. The symptoms appeared after a migraine attack and had not alleviated. The patient reported a sensation of constant 'TV screen snow'. A neurological examination found no signs of focal damage to the nervous system. The results of the ophthalmological examination, MRI of the brain with contrast, MRI of the eye sockets, and EEG were normal. VSS is a phenomenon that is still not fully understood, different from migraine aura and associated with a number of additional symptoms. VSS is very difficult to treat. In this case, a lot of drugs were used without improvement. Further research must be conducted to determine the best treatment options for these patients.

Automatic data-driven design and 3D printing of custom ocular prostheses.

Millions of people require custom ocular prostheses due to eye loss or congenital defects. The current fully manual manufacturing processes used by highly skilled ocularists are time-consuming with varying quality. Additive manufacturing technology has the potential to simplify the manufacture of ocular prosthetics, but existing approaches just replace to various degrees craftsmanship by manual digital design and still require substantial expertise and time. Here we present an automatic digital end-to-end process for producing custom ocular prostheses that uses image data from an anterior segment optical coherence tomography device and considers both shape and appearance. Our approach uses a statistical shape model to predict, based on incomplete surface information of the eye socket, a best fitting prosthesis shape. We use a colour characterized image of the healthy fellow eye to determine and procedurally generate the prosthesis's appearance that matches the fellow eye. The prosthesis is manufactured using a multi-material full-colour 3D printer and postprocessed to satisfy regulatory compliance. We demonstrate the effectiveness of our approach by presenting results for 10 clinic patients who received a 3D printed prosthesis. Compared to a current manual process, our approach requires five times less labour of the ocularist and produces reproducible output.

What do we miss in this Orbital Retinoblastoma?

Introduction : Orbital retinoblastoma (RB) is a dire event with a bleak prognosis. This report highlights the severe complications of retinoblastoma resulting from insufficient diagnostic and treatment efforts due to inadequate medical resources and socio-economic challenges.
 Case Illustration : A 4-year-old boy was brought in with swelling on his left eye socket and jaw, present for two months.He had exhibited leukocoria followed by proptosis 12 months prior and underwent enucleation without dermato-fat graft (DFG) five months ago. Histopathology revealed retinoblastoma without optic nerve invasion. Despite referral to a regional hospital for chemotherapy, he did not receive treatment due to socio-economic constraints. Two months post-operation, the left eye prosthesis spontaneously dislodged, accompanied by an enlarging eye and a left jaw mass. An ophthalmologic assessment disclosed a mass in the left orbital socket, while the right eye appeared normal. A CT scan identified masses in the left orbit, parotid, and masticator spaces, as well as bilateral colli lymphadenopathy. The patient was diagnosed with residual retinoblastoma and received chemotherapy.
 Discussion : Imaging is crucial in proptosis patients to determine tumor extent and management strategies. The standard approach involves initial chemotherapy, surgery, radiotherapy, and additional chemotherapy. High-risk histological features (HHRF) also warrant chemotherapy, although the presence of such features remains undetermined in this case. Employing multiple treatment modalities may enhance prognosis.
 Conclusion : Thorough examination and management are essential in retinoblastoma cases. Patient family education and diligent care play a crucial role in preventing the progression and spread of retinoblastoma.

Prospective Study on the Surgical Outcome of Eyelid Carcinoma

Abstract
 Introduction & Objectives : Introduction Resection of eyelid carcinoma may lead to a risk of recurrences which might increase if excision was incomplete. Risk factors of incomplete surgical removal and recurrences are deep infiltration, spreading outside the macroscopic border, eye socket penetration, and histological type of the eyelid carcinoma. Objective To evaluate the surgical outcomes of eyelid carcinomas.
 Methods : This is a hospital based prospective observational study involving 16 patients. Prior to the surgery patients were evaluated for visual acuity, intra ocular pressure, extra ocular motility, fundus examination, and local clinical examinations. The eyelid carcinomas were histological detected concerning carcinoma type and margin involvement. Local anesthesia was applied. Patients were evaluated 1 month, 3 months and 6 months after surgery for local complications, patients satisfaction on surgical results, and recurrences. The surgical technic applied in this study were also observed.
 Results : Dominant tumor type were basal cell carcinoma and squamous cell carcinoma (87, 44%). The locations were at right and left lower eyelid with percentage of 68. 7 % and 31. 3 % respectively. All patients satisfied on surgery outcomes (100%). Three patients (6. 25 %) with complications were found within 6 months after the surgery. There were no recurrences during follow up period. Surgery procedures applied were modified hughe’s procedure (56. 25%) and mass excision and reconstruction (43. 75%).
 Conclusion : There was less complications and no recurrences within 6 months after surgery. All patients satisfied with the surgical outcomes.

ENUCLEATION OF BULBUS OCULI PROLAPSUS IN TERRIER MIX

An 8-year-old female Chihuahua mix terrier breed with a body weight of 3.3 kg was brought to the Teaching Animal Hospital, Faculty of Veterinary Medicine, Udayana University. The dog was brought in with a complaint of the right eye coming out of the eye socket after fighting with a large breed dog. The purpose of this article is to find out the process of lifting the eyeball using the trans-conjunctival enucleation method. The results of the physical examination showed damage and no response to the case dog's right eye. Based on history and physical examination, the dog was diagnosed with bulbus oculi prolapse. Premedication was carried out by administering 0.3 ml of atropine sulfate and induced anesthesia with 0.2 ml and 0.3 ml of xylazine and ketamine respectively. The postoperative care given was e-collar fitting, giving cefadroxil monohydrate 22mg/kgBB q12h for 5 days, giving anti-inflammatory tolfenamic acid injection 0.3 mg/kgBW and continued with giving meloxicam 1 mg/kgBBq12h for 5 days, and ointment. Bioplacenton® skin is given sufficiently until the wound dries. On the seventh day after surgery, the case dog was declared cured with the surgical wound closed on the right eye after routine postoperative care.

TREATMENT OF BULBUS OCULI DEXTRA PROLAPSE IN MIX POM DOGS

Prolapse of the bulbus oculi is a condition where the eyeball protrudes from the eye socket, which occurs due to impact, blunt trauma, fights or tumors. A Mix Pom purebred dog, named Koko, male, 7 years old, 5.21 kg body weight and brown hair color, complained of the right eyeball protruding from the eye socket since two days. The purpose of writing this case report is to describe the process of lifting the eyeball by cutting the tissue and the nerves inside it using the enucleation technique. From physical examination and clinical signs, the case dog was diagnosed with prolapse of the dextra bulbus oculi with a fausta prognosis. Case dogs were treated with bulbus oculi enucleation surgery, which is a surgical procedure by lifting the eyeball from the eye socket. The surgery was performed under a combination of xylazine and ketamine general anesthesia. Postoperative case dogs were given cefotaxime antibiotics at a dose of 20 mg/kg body weight for two days and followed by oral antibiotic cefixime trihydrate at a dose of 10 mg/kg body weight for five days. Anti-inflammatory in the form of tolfenamic acid with a dose of 4 mg/kg body weight intramuscularly for two days and followed by oral anti-inflammatory dexamethasone tablets 0.25 mg/kg body weight (2 x daily) for five days. The results of the operation showed wound healing on the 10th day, which was indicated by the stitches that had dried and merged, and the dog was active again. Advice that can be given is that a dog suffering from bulbus oculi prolapse must be immediately acted upon, so as not to worsen the dog's condition and to prevent various complications, one of which is miasis.

Direct brow lift – indications, diagnostics, operating techniques

Eyebrow lift is one of the most effective rejuvenating procedures in facial plastic surgery. Lifting the aging soft structures around the eye socket yields both cosmetic and, in some cases, therapeutic effects. Regardless of the indications, preoperative assessment of the patient should be based on a thorough interview, establishing the patient’s expectations, determining the achievable outcome of the procedure, and anticipating potential complications. During the physical examination, it is crucial to identify relevant anatomical structures, assess facial symmetry, scope, and the technique of the procedure. Often, patients opt for combining direct eyebrow lift with eyelid surgery, significantly enhancing the overall result. The primary complication of direct eyebrow lifting is a visible scar, which may be a contraindication for individuals prone to keloid formation and those with a brow deficit. The aim of this study is to define the indications, diagnostics, and describe the surgical techniques used in eyebrow lift procedures.

Grzyby pleśniowe w środowisku człowieka – lekceważone niebezpieczeństwo

IntroductionAccording to Dz. U. nr 75 of 15 June 2002, building law does not allow visible signs of mold fungi in rooms used by people and imposes immediate renovation because of exposure to spores. Which being absorbed via airway and skin may be main sources of three forms: infection, allergy and toxicity. Mycotoxins get to the organism via digestive tract or airway with dust particles or food.Caused illnessesDry eye syndrome, eye socket necrosis, acute, persistent poisoning, impaired immunity, sinusitis, pharyngitis, bronchitis, pneumonia, asthma, air and skin allergy, headache, muscle aches, artralgia. Constant irritability, fatigue, insomnia, reduce concentration, memory disorder, even depression. In the digestive tract disturb metabolism, in extreme cases causing cirrhosis, even cancer; disorder pancreas, ovaries, prostate, and lead to sterility, kidney dysfunctions. Growth of fungi is connected with insufficient heating and ventilation. It is derivative socio-economic factors, hygiene level and health care.PurposeIs presentation of the resulting threat from fungal spores and toxins exposure which are inside our houses, schools, hospitals, even our food based on available medical literatureConclusionsMold Fungal toxins have an effect teratogenic, mutagenic and genotoxic inducing damaging many organs in experimental animals. Illnesses and deterioration of health are not connected with spores and toxins exposures. It may lead to wrong diagnosis and not eliminate fungi from the environment, what cause exacerbating symptoms. Fungal infection may be similar to other illneses as: tuberculosis, molluscum contagiosum, cryptococcosis, histoplasmosis what can delay proper diagnosis and significantlyreduce chances of survival. Species: <i>Cladosporium, Alternaria, Aspergillus</i> and <i>Penicillium</i> were found in high concentrations ta astmatic patients houses. It was connected with asthma symptoms deterioration in 36% to 48% cases.

Аcute sinusitis as a cause of orbit phegmon in a newborn child

Orbital complications of varying severity caused by acute sinusitis are relatively common in pediatric practice. These complications develop depending on the anatomical features of the paranasal sinuses and eye sockets in children and immune system impairment.
 AIM: To present a clinical case of orbital phlegmon in a newborn child.
 RESULTS: A 17-day-old female infant was admitted to the Infectious Diseases Department of the Altai Regional Center for Maternal and Childhood Protection. After self-treatment, her health status did not improve; thus, she was hospitalized. After additional instrumental methods of research, the following diagnosis was made: рhlegmon of the left orbit, subperiosteal abscess on the left, and ethmoiditis with destruction on the left. A consultation of specialists (an ophthalmologist, otorhinolaryngologist, and neonatologist) determined the further management approach.
 CONCLUSION: Orbital complications in pediatric practice require an immediate assessment of the clinical condition by an otorhinolaryngologist and an ophthalmologist. The clinical case presented focuses on the need for an interdisciplinary approach and hospitalization in the initial disease stages to provide therapy because the infection may spread to the intracranial region.

Analysis and Evaluation of Muscle Quality in Different Parts of the Bighead Carp (Aristichthys nobilis).

In this study, the bighead carp (Aristichthys nobilis) was the object of research to compare and analyze the contents of conventional nutrients, amino acids, fatty acids, inosinic acid, and earthy-smelling compounds (geosmin and 2-methylisoborneol) in muscles of its dorsal, belly, tail, opercula, eye socket, and mandible in order to evaluate their quality. The findings could inform recommendations for the consumption and processing of different muscle parts of the bighead carp. The results showed that the water content in the abdominal muscle was significantly lower than that in other parts, and the crude fat content was significantly higher than that in other parts (p < 0.05, the same below). Seventeen kinds of amino acids were detected in the muscles of the six parts of the fish, and the dorsal muscles had the highest umami amino acids, essential amino acids and total amino acids, which were 6.45 g/100 g, 6.82 g/100 g and 17.26 g/100 g, respectively. The total amount of essential amino acids in the muscle was higher than that in the FAO/WHO standard model. According to the AAS standard, the first limiting amino acid in the muscle of the six parts was valine (Val). There were 26 kinds of fatty acids in the abdomen, under the gill cover and in the eye socket muscles, and the content of polyunsaturated fatty acids in the mandibular muscles was the highest (45.41%). The content of inosine in the dorsal muscle was significantly higher than that in other parts. Geosmin was the main substance in the muscle. There was no correlation between the distribution of earthy-smelling compounds and fat content, but the content of earthy-smelling compounds in the muscle of the belly and eye socket was the highest. Therefore, the muscle quality of different parts of the bighead carp has its own characteristics, and targeted development and utilization can make more efficient use of bighead carp resources.