Water vapor plays a vital role in the development of heavy rainfall system. The “21.7” Henan rainfall event, a record-breaking event, was investigated from the perspective of water vapor based on in-situ measurements, namely the 220 continuously operating GNSS ground stations in Henan Province, with GNSS tomography technique. Results showed that during and after the heavy rainfall, the error RMS of water vapor density from tomography was 21 % lower than that of GFS prediction data at the height of about 1450 m by comparing with radiosonde data. Taking ERA5 as the reference, the average relative error of tomographic water vapor density at the height below 4 km was within 10 % before and during the rainfall. The analyses of spatiotemporal variations of water vapor illustrated that tomographic products can, compared to ERA5 reanalysis data, more distinctly reflect the formation and convergence process of low-level water vapor bands before the occurrence of the extreme rainfall, as well as the fracture of the water vapor bands before the end of the rainfall. By combining the tomographic water vapor and GFS wind field data, the water vapor flux divergence can be calculated to further elucidate the movement of water vapor where significant variations of water vapor at the height of 10 to12 km (near the tropopause) and 1 to 4 km in both the vertical and horizontal directions were found before the extreme precipitation.