Onion Extract Research Articles

Comparison Of The Effectiveness Of Grape Seed And Onion Extract In Healing Cut Wounds In Wistar Rats

In healing cut wounds, generally many use drugs with chemicals, the use of chemicals in wound healing has a lot of negative impacts, therefore it is necessary to conduct further research on the benefits of natural ingredients such as plants to treat cut wounds, some of the advantages of using medicinal plants include relatively safer, easy to obtain, cheap, does not cause resistance, and relatively harmless to the surrounding environment or the mixture between the plants, which has been used for treatment for generations. One way to treat cut wounds is to use herbal plants because they are cheaper, easier to get, and have low side effects. Compounds that play a role in the healing process of cut wounds include flavonoids, saponins, tannins, polyphenols, and essential oils. One of the plants that has health benefits is grapes. The purpose of this study is to find out the comparison of the effectiveness of grape seeds and onion extract in healing cut wounds in wistar rats. The type of research used in this study is experimental research with a true experimental method with a post-test only control group design pattern. The sample to be used in this study is 24 rats divided into 4 groups so that each group contains 6 rats. Data analysis uses the One-Way ANOVA test. The results showed that shallot gel extract had a significant effect on the percentage of reduction in incision length.

Vegetables Treated before Drying with Natural Antioxidants plus UV-C Improve Colour and Bioactive Compounds

The quality of minimally processed fruits and vegetables is essential for consumers’ health and effective marketing. This study investigates the effects of UV-C irradiation, applied alone and combined with various natural antioxidants, on the preservation of bioactive compounds and the colour of dehydrated fruits and vegetables. To achieve this, red peppers, yellow peppers, tomatoes, zucchini, eggplants, and melons were subjected to pre-treatments with natural antioxidants and UV-C before processing using low-temperature airflow (50 °C). The drying kinetics showed typical curves of hygroscopic materials, while the drying time was high due to the low temperature applied. The higher drying rate was found for eggplant, due to its porosity, thus allowing a faster moisture removal. The application of antioxidants and UV-C treatments effectively preserved the colour parameters L*, a*, and b*, while in the case of untreated dried vegetables, a significant worsening of colour parameters was noted. However, most applied pre-treatments had positive effects on bioactive compound losses. The best results were obtained using a combination of UV-C with one antioxidant mix that was composed of vanillin, rosemary, and citrus extracts, and combined with a mixture of olive, onion, garlic, and citric acid extracts, which was highly effective in preserving the colour and bioactive compounds of most dried vegetables.

Selective Detection of Picric Acid by Benzodiazepine Containing Enaminone Core as Receptor and Its Application to Real Water Sample Analysis.

Nitroaromatic compounds are highly explosive and illegitimate substances. Over a decade, chemists have been affianced in extensive research on the selective and sensitive detection of these nitroaromatic explosives for homeland security and environmental protection. The benzodiazepine-based enaminone (BDE) receptor has been synthesized by aqueous extract of onion catalyzed three-component reaction between o-phenylenediamine, dimedone with an aldehyde. The BDE probe is well analyzed and applied to a sensor that selectively detects picric acid (PA). UV-Vis and fluorescence spectroscopy were used to investigate the photophysical responses of the receptor (BDE). From the observed results BDE found turn-off fluorescence with the addition of picric acid and the lowest limit of detection and limit of quantification was achieved about 24.6 nM and 73.8 nM. The fluorescence quantum yield was attained about 0.28. The BDE-PA adduct formation was confirmed by 1H NMR titration analysis. The Job's plot analysis was performed through 1H NMR titrations and established the binding stoichiometry ratio of the BDE-PA adduct as 1:1 ratio. Further, DFT calculations supported the observed photophysical responses of BDE-PA adduct to confirm the molecular level interactions. The receptor was effectively applied to approximate level of picric acid in real water sample analysis.

Comparison of the Use of Plant Growth Regulators (PGR) of Red Onion and Shallot Extracts on the Growth of Green Spinach Plants (Amaranthus sp.)

Green spinach is one type of vegetable commodity that the people of Indonesia most widely consume because it has a relatively high nutritional content such as iron, vitamin C, protein, and carbohydrates. However, currently, there is a decrease in green spinach vegetable productivity in Indonesia due to several things, including cultivation techniques that could be more optimal, low seed quality, and limited application of agricultural technology. For this reason, agrarian intensification is needed by using natural plant growth regulators (PGR) to increase the growth of green spinach. Red onions and shallots are part of the allium genus, which has growth phytohormones, namely auxin and gibberellins, which have the potential to be natural PGR. This study aims to compare the use of red onion and shallot extracts in increasing the growth of green spinach plants. The research design used was a randomised group design (RGD) with variations in extract concentrations (0%, 15%, 30%, 45%). Parameters of observation of green spinach plant growth are plant height, number of leaves, leaf circumference, and wet biomass of harvested plants. The application of red onion and shallot extracts was carried out on green spinach plants aged seven days after planting (DAP) with a time interval of 1 week until 28 DAP. Observation of green spinach plant growth parameters began at the age of 14-35 DAP. Statistical analysis of the data using analysis of variance (ANOVA) and then the Duncan Multiple Range Test (DMRT) further t-test a 5% significance level. The results showed that red onion and shallot extracts affected all observed growth parameters of green spinach plants. Shallot extract with a concentration of 45% gave the best results on all green spinach plant growth parameters.

Effect of Natural Growth Regulators on the Growth of Coffee Seedlings in the Cotyledon Phase

Coffee is an important agricultural commodity with increasing global demand, so optimizing the growth of coffee seedlings, especially during the seedling phase, is crucial to increase productivity. The use of natural plant growth regulators offers an environmentally friendly and economical solution. This study aims to evaluate the effect of natural plant growth regulators from onion extract and bean sprout extract on the growth of robusta coffee seedlings (Coffea canephora L.) during the seedling phase. The study was conducted using a Randomized Block Design (RBD) with three treatments, namely control, onion extract, and bean sprout extract. The parameters measured included plant height, stem diameter, and number of leaves for six weeks. Data were analyzed using ANOVA and BNT test at the 5% level. The results showed that both natural plant growth regulators significantly increased the growth of coffee seedlings compared to the control. Bean sprout extract gave the best results for plant height (16.75 cm), while onion extract was superior in increasing stem diameter (4.65 mm) and number of leaves (12.20). Statistical analysis confirmed significant differences between treatments and controls for all parameters. Thus, the use of onion and bean sprout extracts as natural growth regulators has proven effective in increasing the growth of coffee seedlings in the seedling phase, offering an environmentally friendly and economical alternative for optimizing the growth of coffee seedlings.

Response of Crude Onion Extract on Carcass Characteristic and Nutrient Digestibility of Broiler Chicken

Response of Crude Onion Extract on Carcass Characteristic and Nutrient Digestibility of Broiler Chicken

Effect of Iron Nanoparticles Prepared from Onion Extract on Cucumber Plant Growth and Production

In recent years, it has been shown that the use of chemical fertilizers negatively affects the environment and public health. Nano fertilizer have been discovered and used, and one of their many advantages is the speed and ease of obtaining them from various plant sources, which are cheap and currently available it's friendly for environment. The field experiment was carried out in the spring season of 2021 in a mixture of salty clay (cohesive soil) for the purpose of studying the effect of spraying synthetic nanoparticles used from iron oxide particles with onion plant extract at concentrations of 100, 200 and 300 parts per million on the growth and yield of cucumber (Cucumis melo var. flexuosus). The prepared nanoparticles were identified by the following assays: UV-visible spectrophotometry, XRD, FTIR, TEM, SEM and AFM. The results showed a significant effect of using Nano pesticides, especially with high concentration, in increasing average plant height, plant dry weight, leaf area and total plant yield. It was concluded from this study that the positive effect of Nano-fertilizer prepared with onion extract on plant growth, which led to an increase in cucumber productivity and the quality of its fruits, from that there is the possibility of using it as an alternative to conditional mineral fertilizers, after conducting several studies on the safety of using these plants treated with Nano-fertilizers for humans.

Evaluation of the Biostimulant Activity and Verticillium Wilt Protection of an Onion Extract in Olive Crops (Olea europaea).

The olive tree is crucial to the Mediterranean agricultural economy but faces significant threats from climate change and soil-borne pathogens like Verticillium dahliae. This study assesses the dual role of an onion extract formulation, rich in organosulfur compounds, as both biostimulant and antifungal agent. Research was conducted across three settings: a controlled climatic chamber with non-stressed olive trees; an experimental farm with olive trees under abiotic stress; and two commercial olive orchards affected by V. dahliae. Results showed that in the climatic chamber, onion extract significantly reduced MDA levels in olive leaves, with a more pronounced reduction observed when the extract was applied by irrigation compared to foliar spray. The treatment also increased root length by up to 37.1% compared to controls. In field trials, irrigation with onion extract increased the number of new shoots by 148% and the length of shoots by 53.5%. In commercial orchards, treated trees exhibited reduced MDA levels, lower V. dahliae density, and a 26.7% increase in fruit fat content. These findings suggest that the onion extract effectively reduces oxidative stress and pathogen colonization, while enhancing plant development and fruit fat content. This supports the use of the onion extract formulation as a promising, sustainable alternative to chemical treatments for improving olive crop resilience.

Water Extract of Onion Catalyst: A Sustainable Approach for the Synthesis of 4-Substituted 1,5-Benzodiazepine Derivatives via an In Situ Generated Enaminones

Background: A simple, convenient and environmentally benign green protocol has been developed for the one-pot synthesis of 4-substituted-1,5-benzodiazepines through three-component reaction of 1,2-diamine, 1,3-cyclic diketone with an aldehyde catalyzed by water extract of onion. The reaction conditions were optimized and the scope of the reaction was extended to various 1,2- diamines, 1,3-cyclic diketones and aldehydes. The main advantages of this method are good to excellent yields, easy workup, simple experimental procedure, and an ability to tolerate a variety of functional groups which gives cost-effective as well as green rewards. The structure of compound 5f was confirmed by single crystal X-ray analysis. Objective: A methodology developed for the synthesizing of 4-substituted 1,5-Benzodiazepine derivatives via enaminones intermediates using 1,2-diamine, 1,3-cyclic diketone and aldehyde in environmentally friendly ethanol as medium. Methods: As a more environmentally friendly catalyst for producing products containing benzodiazepines using aqueous extract of onion. The devised method was proven reliable, non-toxic and greener solvent with quick work-up to produce the intended product. Results: Here, using a one-pot, three-component reaction with a dimedone, 1,2-diamine and range of aldehyde while using water extract of onion as a catalyst. The acquired experimental results showed that the employed synthesis methodology is a straightforward procedure that offers various benefits, including sustainability, easy separtion from the reaction medium. Conclusion: We have developed a sustainble approach for synthesizing benzodiazepine from radily available precursors under mild reaction conditions.

Pengaruh Air Kelapa, Ekstrak Bawang Merah dan Ekstrak Rebung Bambu Terhadap Perkecambahan Benih Kopi Robusta (Coffea canephora)

Background: Robusta (Coffea canephora) is one type of coffee widely cultivated in Indonesia and is one of the leading commodities. Coffee seeds include seeds that have a long dormancy period that inhibits the germination process. Breaking dormancy can be done by several methods, one of which is soaking in natural growth regulators. Soaking treatment with natural growth regulators can be combined with soaking time treatment to break dormancy. This study aimed to determine the combination of natural growth regulator treatment and the right soaking time for Robusta coffee seed germination. Methods: This research is a 3-repeat Complete Factorial Randomized Design Experiment with the first factor of natural growth regulators type, which consists of 4 levels, namely: Z0 = control; Z1 = coconut water; Z2 = onion extract and Z3 = bamboo shoots, and the second factor is the length of soaking which consists of 3 levels, namely P1 = 12 hours; P2 = 24 hours and P3 = 36 hours. Results: Natural growth regulators' treatment of shallot extract with 24 hours of soaking time gave the best results on all parameters. Conclusions: Using natural growth regulators from coconut water, shallots, and bamboo shoots with several soaking times affects all parameters observed, both in single and combined administration.

Alliaceae-Derived Supplementation Improves the Severity of COVID-19 Symptoms among Elderly Nursing Home Residents.

This study investigates the effect of daily consumption of a concentrated garlic and onion extract on COVID-19 symptoms among elderly nursing home residents. Volunteers consumed a daily capsule of the concentrated powder rich in organosulfur compounds over 36 weeks during lunch. The incidence and severity of COVID-19 symptoms between the treatment and control groups were compared, along with monitoring the safety of consumption, incidence of other diseases, and medicine usage. The treatment group showed a significant reduction in both the number and severity of COVID-19 symptoms compared to the control group, with no significant adverse effects observed. No significant reduction in symptom duration was detected. This study provides preliminary evidence that concentrated garlic and onion extract may aid in the treatment of COVID-19 among older adults. These findings suggest potential public health benefits, emphasizing the need for further research to explore the immunomodulatory properties of these natural compounds.

In Vitro Antifungal Efficacy of Allium Cepa And Allium Sativum: A Comparative Study with Commercial Drugs

The in vitro activities of water, methanol, acetone, ethanol, and chloroform extracts of garlic (Allium sativum) and Onions (Allium cepa) were investigated. For comparison, activities of commercially sold antifungals viz Nystatin, Fulcin, and Cotrimoxazole against Aspergillus niger, Aspergillus fumigatus, Aspergillus flavus, Penicillium spp, Trichophyton schoeleinii, and Neurospora clasa were also investigated. The largest zone of inhibition was exerted by the ethanol and water extracts of garlic (Allium sativum) against Aspergillus niger, A. fumigatus, T. Schoeleilnii, and penicillium spp. The antifugal activity of onions was less marked while its water extracts showed no activity. The lack of inhibition on Neurospora clasa was conspicuous for both the garlic (Allium sativum) and Onions (Allium cepa) extracts. The commercial drugs were significantly more active against the tested fungi (MIC range 1.56-50ug/ml). Fulcin showed more activity than the rest of the commercial drugs tested. The activities of fulcrum for all the fungal species far surpassed those of nystatin and were even superior to those of Cotrimoxazole on Aspergillus niger and Aspergillus fumigatus. Nystatin showed a higher MIC range of 12.5-50 µg/ml for the tested fungal species. The MFC of the drugs was mostly 2-3 times their MIC values. These results suggest that overall, the fungal species tested showed more sensitivity to the commercially sold antifungals than that of the extracts.

LDL-Cholesterol-Lowering Effects of a Dietary Supplement Containing Onion and Garlic Extract Used in Healthy Volunteers.

Hypercholesterolemia plays a pivotal role in the development and progression of cardiovascular diseases, and its prevention seems to be a crucial healthcare strategy to ameliorate these conditions. Subjects with mild hypercholesterolemia are frequently advised against using cholesterol-lowering drugs due to potential side effects, with an emphasis instead on prioritizing dietary adjustments and lifestyle modifications as the primary strategy. In this context, the use of dietary supplements based on medicinal plants may be recommended as a complementary approach to managing elevated cholesterol levels. The aim of this study was to investigate the safety and potential therapeutic effectiveness of a standardized formulation containing extracts from garlic and onions in addressing the health concerns of individuals with slightly elevated cholesterol levels. A controlled, randomized, double-blind, two parallel-group study was conducted over 8 weeks, with clinical visits scheduled at baseline, weeks 2 and 4, as well as at the end of the study. The results revealed significant reductions in both low-density lipoprotein cholesterol and total cholesterol levels among participants who received the extract. Additionally, improvements in blood pressure, as well as in oxidative and inflammatory markers were observed, thus suggesting its potential as a valuable therapeutic intervention for managing mild hypercholesterolemia.

Integrated enzymatic hydrolysis of crude red onion extract and yeast treatment for production and purification of short-chain inulin and inulin neoseries oligosaccharides

As has been confirmed in our previous study, red onion is a promising source of inulin-fructan, inulin neoseries fructan, and their fructooligosaccharides (FOSs). Short-chain FOSs (SCFOSs) are potential prebiotics as they provide many health promoting benefits. However, short-chain inulin neoseries oligosaccharides isolated from plants have scarcely been studied. After prebiotic production, a purification step is essential to produce a functional prebiotic. The aim of this study was to develop new processes of integrated enzymatic hydrolysis of crude red onion extract and yeast treatment for production and purification of SCFOSs. Endo-inulinase is a key enzyme for hydrolysis of crude red onion extract to produce SCFOSs, while Candida orthopsilosis FLA44.2 was employed for purification of the produced SCFOSs. Three different strategies, including two-step (TSP), simultaneous (SP), and semi-simultaneous (SSP) production processes, were designed and investigated as potentially simple, cost-effective, and timesaving production processes. The SP and SSP processes met the objective criteria by exhibiting desirable yields of SCFOSs and the optimal purity of SCFOSs when compared with the TSP process. Notably, the SP process was highlighted as it was simpler than the SSP process. Under optimal conditions (0.4 U of endo-inulinase/g total fructans, 5 % v/v of yeast inoculum and reaction time of 72 h), the SP process conducted in 1-dm3 flasks produced SCFOSs of 87 g/dm3 with neo-GF2 as the main constituent (42 g/dm3) and a purity of 100 %. The ratio of total SCFOSs to total fructans was 0.93 indicating that fructans of the red onion extract have been transformed to SCFOSs.

5-Oxo-7,7-Dimethyl-5,6,7,8-Tetrahydro-4-H-Chromene Bearing N, N-Dimethylaniline as Turn-Off Fluorescent Chemosensor for Picric Acid in Real Water Sample.

We have synthesized a one-pot, three-component pyran-based fluorescence chemosensor using onion extract as a green catalyst. The confirmed structure of the 1:2 binding of receptor SPR-2-picric acid adduct revealed that the pyran-based receptor accommodated two guest picric acid molecules through non-covalent interactions. UV-Vis and fluorescence spectroscopy show high selectivity and sensitivity towards picric acid. The 1D/2D NMR and Job's plot analysis show the complexation and stoichiometric binding of the receptor SPR-2 with picric acid are 1:2. The 1H NMR spectral studies confirm that the formation of receptor SPR-2-picric acid adduct via weak hydrogen bonding. The cooperativity of the receptor SPR-2-picric acid adduct shows negative cooperativity due to the weak hydrogen bonding of receptor SPR-2 and picric acid. Further, the density functional theory (DFT) confirmed the molecular level interaction of the SPR-2 and receptor SPR-2-Picric acid adduct. The receptor was effectively used to assess picric acid concentrations in real water samples.

SINTOMATOLOGIA E MÉTODOS ALTERNATIVOS DE CONTROLE DE PRAGAS NO VIVEIRO FLORESTAL DA UFAM

Pest management in forest nurseries is crucial for ensuring the health of seedlings and the success of reforestation projects. At the forest nursery of the Federal University of Amazonas (UFAM), the pursuit of sustainable methods led to the evaluation of six alternative control techniques and one chemical treatment. The methods investigated included the insecticide FORTH (deltamethrin), mineral oil, onion extract, neem oil (Azadirachta indica), garlic extract, and garlic macerate. The study aimed to compare the effectiveness of these methods in reducing the infestation of scale insects (Dactylopius coccus) on Cenostigma tocantinum seedlings. A 7 x 3 factorial design was used, with 42 seedlings divided among treatments and infestation levels (high, medium, and low). Weekly observations and infestation analyses revealed that treatments with FORTH, mineral oil, and onion extract were the most effective, reducing infestation to low levels in 28.57% of the seedlings. In contrast, neem oil and garlic extract showed low effectiveness, with high infestation intensity persisting. This study demonstrates that alternative methods, such as plant extracts and mineral oils, can offer viable and sustainable solutions for pest control in forest nurseries, contributing to more ecological management practices.

Hallazgos histopatológicos en nematodos Anisakidae, expuestos a extractos acuosos vegetales con capacidad nematicida <i>in vitro</i>

Objetive. Expose nematodes of the Anisakidae family to different aqueous extracts and identify the aqueous extracts with nematicidal capacity. Material and methods. The concentrations of the bioactive compounds of the aqueous extracts of epazote (Dysphania ambrosioides), onion (Allium cepa), siempre viva (Kalanchoe pinnata) and xoconostle (Opuntia oligacantha) were identified. Live parasites of the Anisakidae family were obtained from Lisa fish (Mugilidae), to be exposed to different concentrations of aqueous extracts. Results. K. pinnata and O. oligocantha presented a higher concentration of bioactive components of polyphenols, flavonoids and tannins; as well as in the antioxidant activity of DPPH and ABTS. Parasite mortality occurred at a concentration of 855 mg/mL for K. pinnata of 100% at 48 hours, and in pulp and whole fruit of O. oligacantha, with mortality of 66% at 72 hours. The main histopathological changes caused by K. pinnata were muscle vacuoles; the whole fruit of O. oligocantha degeneration of the intestinal epithelium and vacuolization; the seed caused edema, intestinal degeneration, and vacuolization. Conclusions. The results indicate that the use of aqueous extracts of K. pinnata and O. oligacantha on nematodes of the Anisakidae family are an option for their use as nematicidal agents.

Protective potential of onion eco-extract: safeguarding chicken patties from oxidative deterioration

ABSTRACT Onions contain valuable phytochemical compounds, including quercetin derivatives. This study explores the potential of onion extract as a natural additive in chicken patties. The optimized conditions involved sonication at 80% for 5 min with a 75% ethanol concentration. The onion extract exhibited total phenolic and flavonoid compound values of 255.63 mg GAE g−1 DR and 196.87 mg QE g−1 DR, respectively. The antioxidant activity of the onion extract was characterized by an IC50 of 12.74 µg/mL. This onion extract was dominated by quercetin derivatives (quercetin 4’-O-β-glycoside and quercetin-3-O-β-glycoside and quercetin-3,4’-O-β-diglycoside). Chicken patties treated with 2% onion extract exhibited superior pH stability, lowest thiobarbituric acid reactive substances level (0.40 mg/kg) and peroxide index (0.77 mEq O2/kg meat) and maintained color stability. Comparative analysis with BHT demonstrated the efficacy of onion extract in reducing lipid oxidation. These findings highlight the potential of a 2% onion extract as effective ingredient for enhancing the quality of chicken products.

Potential of Green Synthesis Using a Nanotechnology Approach to Enhance the Biological Properties of Onion Extracts

Potential of Green Synthesis Using a Nanotechnology Approach to Enhance the Biological Properties of Onion Extracts

Anti-parasitic activity of garlic (Allium sativum) and onion (Allium cepa) extracts against Dactylogyrus spp. (Monogenean) in Nile tilapia (Oreochromis niloticus): Hematology, immune response, histopathological investigation, and inflammatory cytokine genes of gills

BackgroundGills monogenean infestation causes significant mortalities in cultured fishes as a result of respiratory manifestation. Medicinal plants are currently being heavily emphasized in aquaculture due to their great nutritional, therapeutic, antimicrobial activities, and financial value.MethodsThe current study is designed to assess the effect of garlic (Allium sativum) and onion (Allium cepa) extracts as a water treatment on the hematological profile, innate immunity, and immune cytokines expression besides histopathological features of gills of Nile tilapia (Oreochromis niloticus L.) infected with gills monogenetic trematodes (Dactylogyrus sp.). Firstly, the 96-hour lethal concentration 50 (96 h-LC50) of garlic extract (GE) and onion extract (OE) were estimated to be 0.4 g/ L and 3.54 g/ L for GE and OE, respectively. Moreover, the in-vitro anti-parasitic potential for (GE) was found between 0.02 and 0.18 mg/mL and 0.4 to 1.8 mg/mL for OE. For the therapeutic trial, fish (n = 120; body weight: 40–60 g) were randomly distributed into four groups in triplicates (30 fish/group, 10 fish/replicate) for 3 days. Group1 (G1) was not infected or treated and served as control. G2 was infected with Dactylogyrus spp. and not exposed to any treatment. G3, G4 were infected with Dactylogyrus sp. and treated with 1/10 and 1/5 of 96 h LC50 of OE, respectively. G5, G6 were infected with Dactylogyrus sp. and treated with 1/10 and 1/5 of 96 h LC50 of GE, respectively.ResultsNo apparent signs or behaviors were noted in the control group. Dactylogyrus spp. infected group suffered from clinical signs as Pale color and damaged tissue. Dactylogyrus spp. infection induced lowering of the hematological (HB, MCH, MCHC and WBCs), and immunological variables (lysozyme, nitric oxide, serum Anti- protease activities, and complement 3). the expression of cytokine genes IL-ß and TNF-α were modulated and improved by treatment with A. sativum and A. cepa extracts. The obtained histopathological alterations of the gills of fish infected with (Dactylogyrus spp.) were hyperplasia leading to fusion of the gill filament, lifting of epithelial tissue, aneurism and edema. The results indecated that G4 and G5 is more regenarated epithelium in compare with the control group.ConclusionA. sativum and A. cepa extracts enhance the blood profile and nonspecific immune parameters, and down-regulated the expression level of (IL-1β and TNF-α).