Extracranial Cerebral Arteries Research Articles

Pathogenetic profile of TIA before 55: A three-year investigation

Fifty-seven cases admitted to the Karolinska Hospital 1973–1976 with the diagnosis transient cerebral ischemia were reviewed. Seventeen cases were excluded as not fulfilling the strict TIA definition. An analysis of the records and the supplementary questionnaire of the remaining cases showed considerable sex differences in the stroke-prone profile. In the male group arteriosclerosis in the extracranial cerebral arteries was demonstrated in 90% of these examined by angiography. In the female group factors recognized as interfering with the coagulation system were obvious in more than 70% and two women had fibromuscular dysplasia. These differences may have therapeutic and prognostic implications. In the total material only 35% had hypertension. Diabetes was not present in any of the patients. Of the men 46.6% had abnormal blood lipids against 15.4% of the women. Seventy-five % of the patients with verified arteriosclerosis were regular smokers. At a mean follow-up time of 18.7 months only one patient, in the untreated group, developed completed stroke.

Recurrent atherosclerotic obstruction of the internal carotid artery five years after endarterectomy.

A patient is described in whom an obstructive atherosclerotic plaque recurred in the cervical portion of the internal carotid artery five years after endarterectomy. The lesion appeared to be a new formation of atheromatous material contiguous to the site of the previous arteriotomy and resulted in neurological symptoms almost identical to those experienced by the patient five years before. This case suggests that the treatment of cerebral ischemia by surgical removal of stenotic lesions in the extracranial cerebral arteries may produce only temporary relief of symptoms and emphasizes the need, following endarterectomy, for medical therapy of the underlying atherosclerotic disease.

Patterns of atherosclerosis of extracranial cerebral arteries.

Patterns of atherosclerosis of extracranial cerebral arteries.

FREQUENCY OF EXTRACRANIAL CEREBROVASCULAR DISEASE IN PATIENTS WITH CHRONIC PSYCHOSIS.

THE concept that significant Central-nervous-system dysfunction may result from occlusive disease of the extracranial cerebral arteries is now well established. The entire spectrum, ranging from mental depression and confusion1 to frank stroke,2 3 4 5 has been found due to cerebral arterial insufficiency. Hunt4 called attention to the role of occlusive lesions of the carotid arteries in producing strokes, and Fisher2 noted the episodic nature of cerebral symptoms in association with advanced atherosclerotic narrowing of the extracranial cerebral vessels. The latter author also found premonitory mental and emotional changes in some patients in whom the stroke syndrome subsequently developed. The frequency of atherosclerotic . . .

Surgical Management of Cerebrovascular Insufficiency

THE patient with signs and symptoms of cerebro-vascular insufficiency presents specific problems relating to diagnosis and treatment. Realizing that widely divergent opinions exist regarding the management of these cases, we consider this report of our experience in the diagnosis and surgical treatment of the extracranial vascular lesions justified.The concept that occlusive disease of the extra-cranial cerebral arteries may produce significant Central-nervous-system dysfunction now appears well founded. Chiari,1 in 1905, emphasized the frequency of atherosclerosis in the region of the carotid bifurcation, believing that these lesions produced cerebral symptoms and lesions by atheromatous embolization. Hunt,2 nine years later, recognized the . . .

Book Review: Cerebral Infarction: The Role of Stenosis of the Extracranial Cerebral Arteries

Book Review: Cerebral Infarction: The Role of Stenosis of the Extracranial Cerebral Arteries

Medical Research Council Special Report Series 300. Cerebral Infarction: The Role of Stenosis of the Extracranial Cerebral Arteries.

Medical Research Council Special Report Series 300. Cerebral Infarction: The Role of Stenosis of the Extracranial Cerebral Arteries.