This study aimed to estimate the total financial (direct and indirect) and avoidable losses related to lameness in Turkish dairy herds. Official and previous published data were used for determining the mean (12.9%) and target prevalence (6.6%) values. Direct financial losses due to lameness were calculated as treatment costs, involuntary culling, and milk yield losses. Indirect losses consisted of extended calving intervals and extra insemination losses. As a result, the average financial loss of lameness per case on dairy farms was $153.8 ($116.8 for mild and $264.7 for severe forms) in Türkiye. Avoidable losses ($75.1) were calculated to be equivalent to 187 liters of cow's milk with current prices for the 2023 year. The share of direct and indirect financial losses was 49.6% and 50.4%, respectively. Total annual losses related to lameness in Türkiye are calculated at $130.5 million (326 million Lt. milk eq.), although $63.7 million (159 million Lt. milk eq.) of the losses could be avoided by farmers. The milk equivalent of avoidable losses corresponds to 0.77% of Türkiye's total annual milk production. In conclusion, lameness causes significant financial losses in Turkish dairy herds. However, almost half of these losses (48.8%) may be avoidable with better management practices which help to increase the productivity and profitability of dairy farmers.