External Root Research Articles

An study of liquidity shock, financial market participation on hollowing behavior of controlling shareholder

Agency conflict between controlling shareholders and small and medium-sized shareholders has become a key issue of concern and research in academia. However, existing studies have less thought about external root causes leading to their hollowing out behavior, especially the lack of in-depth research on the role of liquidity shocks in the mechanism between hollowing out behavior and market participation. Based on market participation perspective, empirical evidence from listed companies from 2006 to 2022, this paper empirically finds liquidity shocks significantly inhibit efficiency of controlling shareholders' hollowing out behavior; at the same time, financial market participation strengthens this inhibitory effect.

USE OF MANUAL SEGMENTATION TO CONTROL UNICYSTIC AMELOBLASTOMA ENUCLEATION: CASE REPORT

A 35-year-old female patient presented an increase in volume in the region of teeth 47 and 48 with a 3-month evolution. Cone beam computed tomography (CBCT) revealed a hypodense image, unilocular with defined limits, causing external root and bone cortical resorption. With the diagnostic hypothesis of unicystic ameloblastoma, the surgical treatment was performed through marsupialization in which the teeth involved were extracted. After confirming the diagnosis through histopathologic examination, the volume was calculated with manual segmentation of the lesion in the first CBCT and in the examination performed 11 months after marsupialization. With satisfactory results, we opted for enucleation and curettage. After 1 year of follow-up the patient shows no signs of relapse, so it is believed that segmentation can be used in the control/monitoring of benign tumors and cystic lesions, providing security to decide when to perform surgical intervention.

Multiple idiopathic external cervical root resorption in patient treated continuously with denosumab: a case report

BackgroundExternal root resorption is an irreversible loss of dental hard tissue as a result of odontoclastic action. Multiple external cervical root resorptions in permanent teeth are rare. The exact cause of external cervical root resorption is unclear. It is currently well established that RANK/RANKL signaling is essential for osteoclastogenesis and osteoclast-mediated bone resorption. Denosumab is an anti-RANKL antibody used for the treatment of postmenopausal osteoporosis. RANK/RANKL pathway suppression by denosumab is expected to suppress the activity of clastic cells responsible for hard tissue resorption involving both osteoclasts and odontoclasts.Case presentationThis case report demonstrates aggressive and generalized idiopathic external cervical root resorption that started and advanced during ongoing antiresorptive therapy with the human monoclonal RANKL-blocking antibody denosumab without discontinuation of therapy in a 74-year-old female patient treated for postmenopausal osteoporosis. The extent of resorptive defects was too large and progressively led to fractures of the teeth. The number of teeth involved and the extend of destruction excluded conservative treatment. The affected teeth had to be extracted for functional prosthetic reconstruction.ConclusionsThis finding suggests that treatment with denosumab may be associated with severe and aggressive odontoclastic resorption of multiple dental roots despite an adequate inhibitory effect on osteoclasts in the treatment of osteoporosis. The RANKL-independent pathways of clastic cell formation are likely to be involved in this pathological process.

Mycorrhizal structures in mycoheterotrophic Thismia spp. (Thismiaceae): functional and evolutionary interpretations

Achlorophyllous, mycoheterotrophic plants often have an elaborate mycorrhizal colonization pattern, allowing a sustained benefit from external fungal root penetrations. The present study reveals the root anatomy and mycorrhizal pattern of eight mycoheterotrophic Thismia spp. (Thismiaceae), all of which show separate tissue compartments segregating different hyphal shapes of the mycorrhizal colonization, as there are intact straight, coiled and peculiarly knotted hyphae as well as degenerated clumps of hyphal material. Those tissue compartments in Thismia roots potentially comprise exo-, meso- and endoepidermae, and exo-, meso- and endocortices, although not all species develop all these root layers. Differences in details among species according to anatomy (number of root layers, cell sizes and shapes) and colonization pattern (hyphal shapes within cells) are striking and can be discussed as an evolutionary series towards increasing mycorrhizal complexity which roughly parallels the recently established phylogeny of Thismia. We suggest functional explanations for why the distinct elements of the associations can contribute to the mycorrhizal advantage for the plants and, thus, we emphasize the relevance of structural traits for mycorrhizae.

A COMPARATIVE EVALUATION OF EXTERNAL APICAL ROOT RESORPTION IN PATIENTS TREATED WITH DAMON BRACKET SYSTEM AND CONVENTIONALMBT BRACKET SYSTEM- A RETROSPECTIVE STUDY

Background: Resorption of the external apical root is a common iatrogenic side effect of orthodontic therapy (EARR). The loss of cementum and dentine is caused by root resorption, which can be a normal or pathologic process. A complicated combination of individual biology and mechanical forces is assumed to be the cause. Aims &Objectives: The purpose of this research was to assess the degree of external apical root resorption (EARR) in patients treated with the Damon self-ligating bracket system to those treated with the conventional MBT bracket system. Methods: For the study, twenty patients were divided into two groups. Ten patients were treated with MBT equipment in Group I. Damon self-ligating appliances were used to treat ten patients in Group 2. The Levander and Malmgren scores were used to assess root resorption on periapical radiographs of the maxillary incisors at the completion of orthodontic therapy. The chi-square test was used to compare root resorption between groups. Results: There was no significant difference in the degree of root resorption between the two groups, according to the findings. Conclusion: Non-extraction therapy with Damon self-ligating or standard preadjusted equipment resulted in similar root resorption, according to the findings.

The influence of bracket torque on external apical root resorption in bimaxillary protrusion patients: a retrospective study

BackgroundTo evaluate the difference in root resorption between standard torque self-ligating brackets and high torque self-ligating brackets in bimaxillary protrusion patients after orthodontic treatment.MethodsPre-treatment and post-treatment Cone beam computed tomography (CBCT) of 32 patients (16 treated with the high torque DamonQ 0.022″ bracket and 16 with the 0.022″ standard torque self-ligating bracket) were selected. The first premolars were extracted from all patients before treatment. After mini-screw implants were inserted into the buccal region between the second premolar and first molar, 150 g of force was applied to retract the upper and lower anterior teeth to close the extraction space on each side. CBCT images of all patients were taken before and after treatment. Three-dimensional reconstruction of the maxillary central incisor, lateral incisor and canine was conducted with Mimics 20.0 software. The volumes of the roots were calculated using Gomagics Studio 12.0 software. The differences between the pre-treatment and post-treatment root volumes were statistically evaluated with a paired-samples t-test.ResultsThere was no statistically significant difference in root resorption degree between the two kinds of torque brackets. The patient’s degree of root resorption in the high torque self-ligating group was greater than that in the standard torque group.ConclusionsThere was no significant difference in root external apical resorption between the high torque self-ligating brackets and the standard torque self-ligating brackets in bimaxillary protrusion patients.

Personalized external aortic root support – how to implant it

Personalized External Aortic Root Support (PEARS) is an evolving method of treatment for patients with a dilated aortic root or ascending aorta. This treatment is being adopted in an increasing number of centres. For the sake of the safety of the procedure a standardized surgical technique is necessary. The authors describe a surgical technique of implantation that is derived from their extensive experience.

Inflammatory response after ExoVasc<sup>® </sup>personalized external aortic root support (PEARS) procedure in patients with Marfan syndrome or non-Marfan genetic aortopathy

Kontext: CĂ­lem studie bylo zjistit zĂĄvaĹžnost zĂĄnětlivĂŠ odpovědi po vĂ˝konu PEARS (personalized external aortic root support) s vytvořenĂ­m personalizovanĂŠho externĂ­ho stentu pro aortĂĄlnĂ­ kořen ve srovnĂĄnĂ­ se standardnĂ­ profylaktickou operacĂ­ aortĂĄlnĂ­ho kořene (standard prophylactic aortic root surgery, SPARS). MateriĂĄl a metody: Studie byla monocentrickou, retrospektivnĂ­ analĂ˝zou nemocničnĂ­ch zĂĄznamĹŻ pacientĹŻ, u nichĹž byla v obdobĂ­ 1998-2017 provedena buď PEARS (skupina PEARS), nebo SPARS (skupina SPARS). U vĹĄech pacientĹŻ se rutinně stanovovaly hodnoty C-reaktivnĂ­ho proteinu (CRP) a počet bĂ­lĂ˝ch krvinek (white blood count, WBC) a provĂĄdělo se echokardiografickĂŠ vyĹĄetřenĂ­. Horečka byla definovĂĄna jako tělesnĂĄ teplota ≥ 38 °C. DiagnĂłza perikarditidy se stanovovala na zĂĄkladě nejmĂŠně tří znĂĄmek z bolesti na hrudi, perikardiĂĄlnĂ­ho vĂ˝potku, elevace Ăşseku ST, zvýťenĂ˝ch hodnot CRP a tělesnĂŠ teploty. VĂ˝sledky: Do skupin PEARS a SPARS bylo zařazeno 13, resp. 14 pacientĹŻ s indikacĂ­ k profylaktickĂŠ operaci aortĂĄlnĂ­ho kořene. VětĹĄina pacientĹŻ v obou skupinĂĄch měla MarfanĹŻv syndrom s kauzĂĄlnĂ­ mutacĂ­ v genu pro fibrilin 1 (FBN1) (62 % vs. 79 %). VstupnĂ­ charakteristiky pacientĹŻ v obou skupinĂĄch byly podobnĂŠ s vĂ˝jimkou aortĂĄlnĂ­ho kořene, kterĂ˝ byl ve skupině SPARS statisticky vĂ˝znamně větĹĄĂ­ neĹž ve skupině PEARS (60 ± 12 mm vs. 48 ± 5 mm; p = 0,003). VĹĄechny operace byly ĂşspěšnĂŠ a proběhly bez větĹĄĂ­ch komplikacĂ­. NejvyĹĄĹĄĂ­ hodnoty CRP a WBC byly statisticky vĂ˝znamně vyĹĄĹĄĂ­ ve skupině PEARS (264,5 ± 84,4 mg/l vs. 184,6 ± 89,6 mg/l; p = 0,034, resp. 15,2 ± 3,8 109/l vs. 11,9 ± 3,3 109/l; p = 0,029). ČasnĂĄ a recidivujĂ­cĂ­ horečka vyĹžadujĂ­cĂ­ opětovnou hospitalizaci se vyskytla častěji ve skupině PEARS (77 % vs. 36 %; p = 0,032, resp. 46 % vs. 7 %; p = 0,020). ČasnĂĄ a recidivujĂ­cĂ­ perikarditida vyĹžadujĂ­cĂ­ hospitalizaci byla rovněž častějĹĄĂ­ ve skupině PEARS (31 % vs. 0 %; p = 0,024, resp. 31 % vs. 0 %; p = 0,024). ZĂĄvěry: Metoda PEARS je velmi slibnĂĄ chirurgickĂĄ metoda; pooperačnĂ­ zĂĄnětlivĂĄ odpověď se vĹĄak vyskytuje častěji a ve srovnĂĄnĂ­ s metodou SPARS je zĂĄvaĹžnějĹĄĂ­. Tyto vĂ˝sledky je vĹĄak samozřejmě nutno dĂĄle zkoumat a ověřovat. © 2021, ČKS.

Establishment of a Personalized External Aortic Root (PEARS) Program: A Single Center Experience

Objective: Personalized external aortic root support (PEARS) is a novel approach in the management of aortic root aneurysms in those with connective tissue disorders. The objective of this study is to review the initial experience and outcomes from a single center. Methods: A PEARS program was established with a proctor present for the first three cases. A retrospective review of all patients undergoing PEARS from 2016 to present was undertaken. Results: We have treated 14 patients to date, 12 isolated PEARS and 2 with concomitant procedures. Of the isolated PEARS patients, mean duration of procedure was 196 ± 31 minutes. Median hospital stay was 7 days (range 4-118). There were no mortalities. Complications included atrial fibrillation (n=2) and transient ST elevation (n=4), late onset pericarditis (n=1). One patient developed intra operative ischemia following mitral repair and PEARS requiring emergency CABG and resulting in a prolonged stay. One patient with Loeys Dietz developed a right coronary artery dissection post operatively which was managed with re-operation, vessel ligation and CABG. Two patients had moderate aortic incompetence which was significantly improved following PEARS. Mean follow up is 1.2 ± 1 years and all patients are well with no acute aortic events. Conclusions: We successfully established a PEARS program. Coronary complications post PEARS can be life threatening. We recommend requesting pre discharge CT aorta for all patients. Longer term follow of aortic dimensions is required to determine efficacy. Further investigation of the role of PEARS in treating patients with aortic regurgitation is required to establish the role of PEARS in this context.

Comparative Evaluation of Root Resorption in Correction of Class II Malocclusion

INTRODUCTION: External apical root resorption is a common iatrogenic side effect of orthodontic treatment and has been reported particularly in anterior teeth. The etiology of resorption is multifactorial, complex and individual susceptibility to resorption depends on various factors.MATERIALS AND METHOD: The degree of root resorption during orthodontic treatment was evaluated on the post-treatment RVGs of the maxillary and mandibular central and lateral incisors of 28 skeletal Class II patients with mandible retrusion treated with non-extraction treatment protocol using elastics and PowerScope. RESULTS: There was no statistically significant difference in root resorption between the groups for the overall score and comparison of root resorption in individual teeth between two groups showed significantly more resorption in PowerScope group in mandibular lateral incisors.CONCLUSION: Both elastic and PowerScope groups showed mostly mild to moderate root resorption which is clinically acceptable and lower lateral incisors showed statistically more root resorption in PowerScope group.

External apical root resorption after molar space closure with miniscrew as anchorage: a tomographic evaluation

Objective: The purpose of this retrospective study was to evaluate and quantify external apical root resorption (EARR) in molars after masialization into atrophic alveolar ridge area. Materials and Methods: The sample consisted of 11 patients, five women and six men, and a total of 16 molars, both superior and inferior (seven in the maxilla and nine in the mandible). The age range was 19 to 55 years at the beginning of treatment (initial mean age of 36 years and 5 months), with an average treatment time of 23 months. Tooth movement was performed with mini-implant anchorage using NiTi springs, using a mean force of 300 grams. The sample was evaluated using cone-beam CT scans (CBCT) in two periods, at the beginning of the treatment (T1) and after 4 mm of movement (T2). Root resorption was measured by the difference in root lengths (T2-T1). Using the distance from the floor of the pulp chamber to the root apex as a reference. Root length was measured using specific software (OnDemand3Ddental) and was analyzed using the paired t-test, adopting a significance level of 5%. Results: There was statistically significant resorption only in the mesial and distal roots, with a mean reduction of 0.69 mm in the mesial root (-6.2%) and 0.83 mm in the distal root (-7.4%). Conclusion: Space closure after dental movement in an atrophic alveolar ridge was identified as a risk factor for ARR. However, the amount of ARR could be considered clinically irrelevant.

A contemporary approach to a young female patient with Loeys-Dietz syndrome and an uncomplicated type B aortic dissection: a case report

BackgroundAortic dissection is a relatively uncommon, but often catastrophic disease that requires early and accurate diagnosis. It often presents in patients with congenital connective tissue disorders. The current aortic surgical techniques are related with serious early and late complications. This case report emphasizes the importance of early diagnosis of aortic root dilatation and the risk of dissection, especially in patients with congenital connective tissue disorders. We present an alternative, contemporary and multidisciplinary approach based on the present state of knowledge.Case presentationWe present a rare case of a young female patient with Loeys-Dietz syndrome who was admitted with an uncomplicated aortic dissection (Stanford type B / DeBakey type III) and a dilated aortic root. After a period of close surveillance and extensive vascular imaging, thoracic endovascular aortic repair was deemed to be technically not possible. Medical treatment was optimized and our patient successfully underwent a personalised external aortic root support procedure (PEARS) as a contemporary alternative to existing aortic root surgical techniques.ConclusionsThis case highlights the importance of interdisciplinary approach, close follow-up and multimodality imaging. The decision to intervene in a chronic type B aortic dissection is still challenging and should be made in experienced centers by an interdisciplinary team. However, if an acute complication occurs, thoracic endovascular aortic repair TEVAR is the method of choice. In all cases optimal medical treatment is important. There is increasing evidence that personalized external aortic root support procedure PEARS is effective in stabilizing the aortic root and preventing its dilatation and dissection not only in patients with Marfan syndrome, but also in other cases of aortic root dilation of other etiologies. Moreover, many publications have reported the additional benefit of reduction or even eradication of aortic regurgitation by improving coaptation of the aortic valve leaflets in dilated aortas.

Root-crown ratio: a new method for measurement of orthodontic external apical root resorption

ABSTRACT Purpose: External Apical Root Resorption (EARR) is an undesirable but unavoidable side effect of orthodontic treatment. The various methods proposed for its evaluation, e.g. Intraoral Periapical (IOPA) X-ray and Orthopantomogram (OPG) x-rays use linear measurements which have errors due to magnification and angulations of x-rays. Root-crown ratio as measured on digital OPGs, which are essential diagnostic records for all orthodontic patients were used for the first time to assess root resorption. Methods: A two-step method was used, first to check the v alidation of OPG measurement with IOPA x rays. The first step involved the measurement of Root-crown ratio on digital OPG and IOPA by 5 independent examiners on IC measure software. The second step involved the measurement of root resorption as Root-crown ratio on pretreatment and post-treatment OPG X rays of 32 treated orthodontic patients all of which were treated by a single orthodontist. Digital OPG images of all patients were traced in Picassa software. In both steps, root-crown ratio was assessed by modified Lind method. Results: The results of first step did not show any significant differences in examiners to read the IOPA and OPG x rays. The results of the second step showed 11.8% root resorption in maxillary central incisors and 4% root resorption in lateral incisors. Similarly, maxillary and mandibular molars showed 1.6% and 5.1% resorption, respectively. The resorption in mandibular molars was significantly more compared to pretreatment value. There was apparently no effect of extraction treatment or treatment time on the amount of resorption. Conclusion: The study concluded that root-crown ratio can be used as an effective and efficient alternative method to quantify root resorption on OPG X rays and possibly alleviate the need for taking IOPA x rays in orthodontic patients thereby reducing the radiation exposure.

Clinical performance of whitening on devitalized teeth: a retrospective observational study

Objective: This retrospective observational study evaluated the clinical performance of intracoronal whitening and correlated the main factors that interfere with its stability and patient satisfaction. Material and Methods: The paper was designed following the STROBE statement. Patients from the Institute of Science and Technology - ICT/UNESP database who underwent nonvital tooth whitening from August 2010 to July 2015 were selected. Data collection was performed by researching the institution records, patients interview, clinical and radiographic examination. Data were analyzed using Mann-Whitney test and Spearman's correlation (p<0.05). Results: The initial search on 1275 records resulted in 43 patients, of whom 18 were selected according to eligibility criteria. There was positive correlation only between the degree of patient’s satisfaction and the perception of color difference after whitening treatment (p<0.05). Color relapse was observed in all conditions, independently of the period of follow-up (p>0.05). There was no case of external cervical root resorption. Conclusion: Color changes after whitening influenced patient’s satisfaction. There was no correlation among the color relapse and height of gutta-percha, return interval or cause of darkening.KEYWORDSTooth discoloration; Tooth nonvital; Tooth whitening.

Reabsorção externa inflamatória após luxação intrusiva dentária – conduta clínica de tratamento tardio

External inflammatory root resorption (EIRR) is one of the consequences of pulp necroses caused by intrusive dislocation (ID). The objective of the study was to report a clinical case of ID associated with EIRR, which was submitted to late endodontic treatment. Patient came to the dental office five months after a trauma with a clinical picture of intrusive dislocation of tooth 21 associated with pulp necrosis, but without symptoms. Radiographic examination showed an image compatible with EIRR along root surface. The treatment plan was to undergo endodontic treatment with calcium hydroxide changes which occurred monthly for 8 months. When EIRR stopped, the root canal was filled. After clinical and radiographic follow up for 5 years, there was an involution of the damage caused by the clastic activity resulting from the resorptive process, characterizing the success of the instituted therapy.

P5610Inflammatory response after ExoVasc personalized external aortic root support (PEARS) procedure in patients with Marfan syndrome or non-Marfan genetic aortopathy

Abstract Background External aortic root support (PEARS) is a novel prophylactic aortic root surgery. Purpose The study aimed to determine the severity of inflammatory response after the personalized external aortic root support (PEARS) procedure in comparison to after the standard prophylactic aortic root surgery (SPARS). Materials and methods The study was a single-centre, retrospective, based on hospital record analysis of patients who underwent the PEARS procedure (PEARS group) or SPARS (SPARS group) during 1998–2017. C-reactive protein (CRP), white blood count (WBC), and echocardiography were routinely obtained. Fever was defined as body temperature ≥38°C. Diagnosis of pericarditis included a minimum of three signs from chest pain, pericardial effusion, ST elevation, elevated CRP, and body temperature. Results PEARS and SPARS groups consisted of 13 and 14 patients, respectively, scheduled for prophylactic aortic root surgery. A majority of patients in both groups had Marfan syndrome with causal mutation in the fibrillin 1 (FBN1) gene (62% vs 79%). Patient baseline characteristics were similar in the two groups, except aortic root was significantly larger in the SPARS group than in the PEARS group (60±12 mm vs 48±5 mm; P=0.003). All surgical procedures were successful and without major complications. The peak values of CRP and WBC were significantly higher in the PEARS group (264.5±84.4 mg/L vs 184.6±89.6 mg/L; P=0.034 and 15.2±3.8 109/L vs 11.9±3.3 109/L; P=0.029). Early and recurrent fever requiring hospital readmission was significantly more frequent in the PEARS group (77% vs 36%; P=0.032 and 46% vs 7%; P=0.020). Early and recurrent pericarditis requiring hospital readmission was also more frequent in the PEARS group (31% vs 0%; P=0.024 and 31% vs 0%; P=0.024). Inflammatory characteristics Postprocedural inflammatory characteristics PEARS group SPARS group P value (N=13) (N=14) Peak level of CRP (mg/L) 264.5±84.4 184.6±89.6 0.034 Peak WBC (109/L) 15.2±3.8 11.9±3.3 0.029 ST elevation (N) 11 (85) 6 (43) 0.024 Early fever (N) 10 (77) 5 (36) 0.032 Recurrent fever (N) 6 (46) 1 (7) 0.020 Early pericarditis (N) 4 (31) 0 (0) 0.024 Recurrent pericarditis (N) 4 (31) 0 (0) 0.024 CRP, C-reactive protein; WBC, white blood count. Echocardiography-signs of inflammation Conclusions The PEARS procedure is an extremely promising surgical technique, but the postoperative inflammatory response occurs frequently and more severely in comparison to SPARS. Clearly, these findings warrant further investigation.

Improvement of Open Bite and Stomatognathic Function in an Axenfeld- Rieger Syndrome Patient by Orthodontic Sectional Arch Mechanics: Clinical Considerations and the Risk of Orthodontic Tooth Movement.

Orthodontists need to understand the orthodontic risks associated with systemic disorders. Axenfeld-Rieger syndrome (ARS) is a rare autosomal dominant disorder with genetic and morphological variability. The risks of orthodontic treatment in ARS patients have been unclear. Here we describe the correction of an anterior open bite in a 15-year-old Japanese female ARS patient by molar intrusion using sectional archwires with miniscrew implants. An undesirable development of external apical root resorption (EARR) was observed in all intrusive force-applied posterior teeth during the patient's orthodontic treatment, suggesting that ARS patients have a higher risk of EARR than the general population.

Aortic Root Surgery in Marfan Disease: Outcome After Contemporary Surgery, Personalised External Aortic Root Support and Microsimulation

Objective: Total aortic root (TRR) and valve-sparing aortic root (VSRR) replacement surgery has improved life expectancy in Marfan disease patients (MFS). Determining the difference in outcomes aft...

The influence of bracket type on the external apical root resorption in class I extraction patients - a retrospective study

BackgroundThe relationship between orthodontic treatment-related factors and EARR has never been fully answered. The aim of this study was to investigate whether conventional and passive self-ligating brackets affect the amount and severity of external apical root resorption (EARR) in withdrawal patients.MethodsNinety-eight patients were selected from department of orthodontic, hospital of stamotology, Wenzhou medical university. Patients received treatment with either a conventional edgewise appliance (n = 49, Mini, 3 M Unitek, USA) or a passive self-ligating bracket system (n = 49, Damon, Ormco, USA). EARR of the maxillary incisors was evaluated on panoramic radiographs at the before and end of orthodontic treatment, respectively. Intergroup comparisons of root resorption were performed with Mann-Whitney tests. The univariate and multivariate regression model was used to assess the appliance type, age, sex and duration of treatment on EARR.ResultsThere was no significant difference in the amount of EARR between the two groups was found. Age and gender were not association with EARR, however, EARR was positively correlated with treatment duration.ConclusionsThe type of bracket did not influence the occurrence and severity of the external apical root resorption in class I extraction patients.

A hybrid approach for quantitative assessment of construction projects risks: The case study of poor quality concrete

This research presents a new fuzzy-based approach for quantitative assessment of construction projects risks. Using the proposed approach, the risk is decomposed into internal and external root causes prompting it and the probability of occurrence of risk is assessed by fault tree analysis (FTA). The impact of identified risks is then assessed by event tree analysis (ETA) considering the possible negative scenarios arising from the occurrence of a risk. Owing to the imprecise and uncertain nature of various factors affecting the probability and impact of identified risks, fuzzy logic is integrated into the proposed FTA and ETA methodologies. Finally, the severity of risk is assessed in the form of a fuzzy number using the proposed integrated fuzzy FTA-ETA approach. To evaluate the performance of the proposed method, it is implemented in a large building project and the quantitative risk assessment is done for the “poor quality concrete” as one of the most significant identified risks.