External Interactions Research Articles

Rigid-Flexible Coupled Dendritic Molecule Doping: General Approach to Activate Commercial Polymers into Harsh Condition-Tolerant Multi-Reusable Strong Supramolecular Adhesives.

Developing functional adhesives combining strong adhesion, good recyclability and diverse harsh-condition adaptability is a grand challenge. Here, we introduce a general dendritic molecule doping strategy to activate commercial polymers into a new family of supramolecular adhesives integrating high adhesion strength, ultralow temperature, water resistant and multi-reusable properties. Our method involves rational design of a new rigid-flexible coupled dendritic molecule-M4C8OH as a versatile dopant, while simple M4C8OH doping into commercial polymers can modulate internal and external non-covalent interaction to enable H-bonding enhanced interchain cross-linking for tough cohesion along with enhanced interphase interaction. This endows 20 wt % M4C8OH-doped polycaprolactone (PCL) adhesives (PCL-M4C8OH) with improved adhesion strength on various substrates with the maximum increase up to 2.87 times that of PCL. In particular, the adhesion strengths of PCL-M4C8OH on polymethyl methacrylate at 25 °C and -196 °C reach 4.67 and 3.58 MPa-1.9 and 2.3 times those of PCL and superior to diverse commercial adhesives and most reported adhesives. PCL-M4C8OH also displays markedly-improved multi-usability and tolerance against ultralow temperature and diverse wet environments. Mechanism studies reveal the crucial role of M4C8OH molecular structures toward superior adhesion. Our method can be expanded to other polymer matrices, yielding diverse new supramolecular adhesives.

Communication behavior and space utilization of office workers in a research facility's activity‐based workplace

AbstractThis study explores the pre‐ and post‐renovation differences in communication behaviors of office workers at a construction company's research facility that had carried out renovations to promote open innovation through internal and external interactions. We conducted an analysis by combining both objective survey of conversation time, conversation partners, and stay location information using sensing terminals and subjective evaluations by office workers using a questionnaire survey. As the work style transitioned from fixed seats pre‐renovation to activity‐based working post‐renovation, the attendance rate analysis around each worker's personal workspace throughout the measurement period decreased from 74% to 60%, and the tendency to use various places in the office increased. Additionally, the number of conversation partners increased by 1.9 times on average and inter‐department conversation rate increased from 46% to 53% when activity‐based working was performed post‐renovation. However, while the introduction of activity‐based working significantly increased the level of communication satisfaction among workers in other departments, it tended to decrease the level of communication satisfaction within a department. This study maintains that organizational and operational efforts must sustain and promote intra‐departmental communication when activity‐based working is introduced and confirms that the introduction of activity‐based working was effective in promoting interaction between office workers.

Enterprise digitization and marine economic performance: An empirical study of listed enterprises in China's maritime economy.

The scale and connectivity of marine resources make them more complex than land resource management. Although digitization has been recognized as an organizational change process that can effectively improve resource efficiency and enhance network resilience, however, gaps remain in establishing the theoretical links between digitization and marine economic performance. Based on a panel fixed-effects model, this study evaluates the interrelationships and potential mechanisms of different firms with data from annual reports of listed firms in the marine economy in the eastern coastal region of China. The results indicate that there is a 'U-shaped' relationship between digitalization and enterprise efficiency in the maritime sector, and significant heterogeneity exists in the characteristics of these enterprises. Notably, firms' technological innovation capability can modulate the 'U-shaped' relationship through the interaction of economies of scale and economies of scope. This paper highlights how digitization mitigates the fragmentation and sectionalization of marine information and addresses the digital overload and productivity paradox that firms may face in the early stages of digitization. The study suggests that institutional diversity shapes resilience. Governments need to promote top-down regulation and industry collaboration, while marine enterprises need to coevolve collaboratively with them through bottom-up internal communication and external interaction to enhance the value chain of marine enterprises.

Letters of Historians of the 2nd Half of the 20th Century as a Channel of Scholarly and Business Communications (Based on Letters from Siberia to the Capital)

The article analyzes the letters of specialists in Russian history of the 17th – 19th centuries who sent correspondences to their colleagues in Moscow. The reason these letters are being analyzed is because, due to the distance and communication methods available at the time, correspondence was the main way for Siberian scholars to communicate with the representatives of the important scientific centers, to stay updated on the latest research trends and discoveries. During this era, authors were comparatively unrestricted in their statements, and their internal and external interactions were diverse and significant. Historians from Siberia and Moscow used to correspond on scientific and organizational matters through letters. The topics of discussions included participation in scientific conferences, invitations, opportunities for business trips, publications, cooperation, and reviews. The scholars shared their professional thoughts, ideas, and plans, characterized the sources they found and analyzed, expressed hypotheses and explained preliminary conclusions, reported the outcomes of research, and sometimes talked about the progress in their research projects and the development in their understanding of scientific problems. The letters often described events in the scientific careers of the authors. The content and emotional tone of the correspondence were significantly influenced by the author's character and relationship with the addressee. The letters often contained information of both scientific and personal nature. Sometimes, Siberian scientists requested assistance and help from their colleagues from the capital. The article concludes that letters were a reliable and effective communication channel among the professional community of historians. They were used to convey scientific, business, and occasionally personal information. The recipients of these letters were typically scholars from Moscow who were older in age and higher in status. As a reference group, they played a significant role in determining the specifics of the letters addressed to them.

Quantum chemical treatment, electronic energy in various solvents, spectroscopic, molecular docking and dynamic simulation studies of 2-amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide: A core of anticancer drug

The titled molecule 2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide (ANMC) is a core of anticancer drug dasatinib (leukemia). Its derivatives exhibited bioactivity against breast cancer. Experimentally, the titled compound was described using NMR (1H NMR and 13C NMR), FTIR and UV–visible spectroscopy. The results were compared with the theoretical predictions, showing good agreement such as theoretical NH vibrations showed symmetric stretching and asymmetric stretching at 3429 and 3440 cm−1 respectively, λmax values appear at 305 nm for experimental and 307.75 nm for theoretical observations in acetone medium. Hirshfeld surface analysis well described the secondary internal and external interactions obtained like dnorm and di ranges −1.8551 to 1.4590 and 0.0918 to 2.6756 respectively. Comparing UV–visible spectra obtained in various solvents with the calculated TD-DFT results revealed minimal solvent effects. Molecular electrostatic potential (MEP) map and Fukui functions were employed, which indicated reactive sites of the molecule and the obtained order of nucleophilic reactivity was C16 > C2 > C8 > Cl1 > C22 > C21. The bioactivity profile probability of ANMC was theoretically explored by calculation of electrophilicity index and drug-likeness. Molecular docking of the ANMC molecule was performed with ten receptors to obtain the best ligand–protein interaction and the minimum binding energy obtained was −8.0 kcal/mol. Biomolecular stability of ANMC was investigated by Molecular Dynamic Simulation (MDS). And also the analysis of free energies showed strong interactions between the ligand and the protein.

Simplified discrete model for axisymmetric dielectric elastomer membranes with robotic applications

Soft robots utilizing inflatable dielectric membranes can realize intricate functionalities through the application of non-mechanical fields. However, given the current limitations in simulations, including low computational efficiency and difficulty in dealing with complex external interactions, the design and control of such soft robots often require trial and error. Thus, a novel one-dimensional (1D) discrete differential geometry (DDG)-based numerical model is developed for analyzing the highly nonlinear mechanics in axisymmetric inflatable dielectric membranes. The model captures the intricate dynamics of these membranes under both inflationary pressure and electrical stimulation. Comprehensive validations using hyperelastic benchmarks demonstrate the model’s accuracy and reliability. Additionally, the focus on the electro-mechanical coupling elucidates critical insights into the membrane’s behavior under varying internal pressures and electrical loads. The research further translates these findings into innovative soft robotic applications, including a spherical soft actuator, a soft circular fluid pump, and a soft toroidal gripper, where the snap-through of electroelastic membrane plays a crucial role. Our analyses reveal that the functional ranges of soft robots are amplified by the snap-through of an electroelastic membrane upon electrical stimuli. This study underscores the potential of DDG-based simulations to advance the understanding of the nonlinear mechanics of electroelastic membranes and guide the design of electroelastic actuators in soft robotics applications.

Molecular influence on nuclear-quadrupole-coupling effects in laser induced alignment.

We computationally studied the effect of nuclear-quadrupole interactions on the field-free impulsive alignment of different asymmetric-top molecules. Our analysis is focused on the influence of the hyperfine- and rotational-energy-level structures. These depend on the number of nuclear spins, the rotational constants, and the symmetry of the tensors involved in the nuclear spin and external field interactions. Comparing the prototypical large-nuclear-spin molecules iodobenzene, 1,2-diiodobenzene, 1,3-diiodobenzene, and 2,5-diiodobenzonitrile, we demonstrate that the magnitude of the hyperfine splittings compared to the rotational-energy splittings plays a crucial role in the spin-rotational dynamics after the laser pulse. Moreover, we point out that the impact of the quadrupole coupling on the rotational dynamics decreases when highly excited rotational states dominate the dynamics.

Orbital Precession in Janis–Newman–Winicour Spacetime

We have investigated the Janis–Newman–Winicour spacetime through three fundamental tests of theories of gravity, namely, gravitational lensing, perihelion shift, and redshift due to gravitational force. Focusing initially on the circular motion of a massive particle within the equatorial plane, the analysis disregards external scalar field interactions. The Janis–Newman–Winicour (JNW) spacetime’s unique parameters, mass (M) and the scalar parameter (n), are examined, revealing an intriguing relationship between the innermost stable circular orbit position of the test particle and the scalar field parameter. The study also explores photon motion around a gravitational object in JNW spacetime, revealing the expansion of the photon sphere alongside a diminishing shadow, influenced by the external scalar field. Despite these complexities, gravitational bending of light remains consistent with general relativity predictions. The investigation extends to perihelion precession, where the trajectory of a massive particle in JNW spacetime exhibits eccentricity-dependent shifts, distinguishing it from Schwarzschild spacetime. Finally, oscillatory motion of massive particles in JNW spacetime is explored, providing analytical expressions for epicyclic frequencies using perturbation methods. The study concludes with the application of MCMC analyses to constrain the JNW spacetime parameters based on observational data.

Biological Cell Response to Electric Field: A Review of Equivalent Circuit Models and Future Challenges.

Biological cells, characterized by complex and dynamic structures, demand precise models for comprehensive understanding, especially when subjected to external factors such as electric fields (EF) for manipulation or treatment. This interaction is integral to technologies like pulsed electric fields (PEF), inducing reversible and irreversible structural variations. Our study explores both simplified and sophisticated equivalent circuit models for biological cells under the influence of an external EF, covering diverse cell structures from single- to double-shell configurations. The paper highlights challenges in circuit modeling, specifically addressing the incorporation of reversible or irreversible pores in the membrane during external EF interactions, emphasizing the need for further research to refine technical aspects in this field. Additionally, we review a comparative analysis of the performance and applicability of the proposed circuit models, providing insights into their strengths and limitations. This contributes to a deeper insight of the complexities associated with modeling biological cells under external EF influences, paving the way for enhanced applications in medical and technological domains in future.&#xD.

A Graph-Informed Modeling Framework Empowering Gene Pathway Discovery.

This study introduces a novel graph-informed modeling framework for improving the statistical analysis of gene expression data, particularly in the context of identifying differentially expressed gene pathways and gene expression-assisted disease classification in a high-dimensional data setting. By integrating gene regulatory network information into hypothesis testing for the difference between mean vectors and linear discriminant analysis, we aim to effectively capture and utilize previously validated external gene interaction information. Our method leverages a block-coordinate descent approach which enables us to incorporate mixed graph information into linear structural equation modeling, accommodating directed/undirected edges and potential cycles in gene regulatory networks. Extensive simulations under various data scenarios have demonstrated the effectiveness of our approach with improved power for gene pathway tests and disease classification over existing methods. An application to a lung cancer dataset from the Cancer Genome Atlas Program (TCGA) further exemplifies the potential of our graph-informed approach in empowering the detection of differentially expressed gene pathways and gene expression-based classification of different lung cancer stages. Our findings underscore the potential utility of incorporating gene regulatory network information in gene pathway analysis, setting the stage for future advancements in gene pathway discovery, disease diagnosis, and treatment strategies.

Solvatochromic and biological studies of new meso-benzodioxole-BODIPY-2-Schiff dye

This paper focuses on solvatochromic studies of a new synthesised BODIPY dye with piperonal and ortho-hydroxy aryl Schiff base substituents (BD-2-Schiff). The studied dye has been analysed by spectroscopic and computational techniques to have a deep insight into the impact of the solvents’ polarity and the specific interactions on the dye characteristics. The synthesized dye turns to be sensitive to external specific interactions, caused by protic solvents and acid, which change spectral characteristics of BODIPY-2-Schiff. The calculations by the density functional theory (DFT) and the time-dependent density functional theory (TD-DFT) have been accomplished for the interpretation of the obtained experimental results. The synthesized dye has been evaluated as a photosensitizer for the light induced inactivation of Staphylococcus aureus (S. aureus) and Acinetobacter baumannii (A. baumannii). The synthesized BODIPY dye has shown a significant photocidal activity (above 90 %) against these pathogenic bacteria at low microgram concentrations and excitation with low doses of visible light (0.72 J/cm2; λ = 519 nm).

Consensus-Based Model Predictive Control for Active Power and Voltage Regulation in Active Distribution Networks

In this paper, a consensus-based model predictive control (Cb-MPC) scheme is proposed to control the active power and voltage at all nodes in grid-connected active distribution networks (ADNs) with multiple distributed energy resources (DERs). The proposed design methodology is based on a multiple-input multiple-output (MIMO) model of an ADN which accounts for both the internal and external interactions among the control loops of the DERs. To achieve the control objective, each DER unit is equipped with a controller–observer system. In particular, the observer implements the consensus algorithm to estimate the collective system state by exchanging data only with its neighbors. The scope of the controller is to solve the MPC optimal problem based on its collective state estimate, and, due to the presence of an integral term in the control action, it is robust against any unknown scenarios of the ADN, which are represented by uncertainty in the model parameters. The results of numerical simulations validate the effectiveness of the proposed method in the presence of unknown changes in the operating conditions of the ADN and of communication using a sample and hold function.

Enabling 3D bioprinting of cell-laden pure collagen scaffolds via tannic acid supporting bath.

The fabrication of cell-laden biomimetic scaffolds represents a pillar of tissue engineering and regenerative medicine (TERM) strategies, and collagen is the gold standard matrix for cells to be. In the recent years, extrusion 3D bioprinting introduced new possibilities to increase collagen scaffold performances thanks to the precision, reproducibility, and spatial control. However, the design of pure collagen bioinks represents a challenge, due to the low storage modulus and the long gelation time, which strongly impede the extrusion of a collagen filament and the retention of the desired shape post-printing. In this study, the tannic acid-mediated crosslinking of the outer layer of collagen is proposed as strategy to enable collagen filament extrusion. For this purpose, a tannic acid solution has been used as supporting bath to act exclusively as external crosslinker during the printing process, while allowing the pH- and temperature-driven formation of collagen fibers within the core. Collagen hydrogels (concentration 2-6mg/mL) were extruded in tannic acid solutions (concentration 5-20mg/mL). Results proved that external interaction of collagen with tannic acid during 3D printing enables filament extrusion without affecting the bulk properties of the scaffold. The temporary collagen-tannic acid interaction resulted in the formation of a membrane-like external layer that protected the core, where collagen could freely arrange in fibers. The precision of the printed shapes was affected by both tannic acid concentration and needle diameter and can thus be tuned. Altogether, results shown in this study proved that tannic acid bath enables collagen bioprinting, preserves collagen morphology, and allows the manufacture of a cell-laden pure collagen scaffold.

Transforming Commercial Polymers into Tough yet Switchable Adhesives by Trident Photoswitch Molecule Doping: Break Adhesion-Switchability Paradox.

Here, a trident molecule doping strategy is introduced to overcome both cohesion-adhesion trade-off and adhesion-switchability conflict, transforming commercial polymers into tough yet photo-switchable adhesives. The strategy involves initial rational design of new trident photoswitch molecules namely TAzo-3 featuring azobenzene and hydroxy-terminated alkyl chains involved rigid-soft tri-branch structure, and subsequent doping into commercial polycaprolactone (PCL) via simple blending. Unique design enables TAzo-3 as a versatile dopant, not only regulating the internal and external supramolecular interaction to balance cohesion and interface adhesion for tough bonding, but also affording marked photothermal effect to facilitate rapid adhesive melting for great photo-switchability. Thus, the optimal TAzo-3-doped PCL (TAzo-3@P) displays markedly-improved bonding performance on diverse substrates compared to linear azobenzene-doped PCL and pure PCL. Impressively, TAzo-3@P on polymethyl methacrylate (PMMA) attains large room-temperature adhesion strength of 6.7MPa - surpassing most reported adhesives and many commercial adhesives on PMMA, along with easy photo-induced detachment with remarkable switch ratio of 2.09×105. Besides, TAzo-3@P can also act as "permanent" adhesives for only adhesion, demonstrating excellent multi-reusability, anti-freezing and waterproof ability. Mechanism studies unveil that the switchable adhesion is closely linked with the dopant molecule structure while rigid-soft coupled trident structures and hydroxy-terminated alkyl chains are key factors.

북한지역 비파형동검문화의 확산과 그 배경 - 기후·금속문명·교류 관점에서

It is necessary to utilize the results of research studies in neighboring regions for research on the Mandolin-shaped Bronze Daggers culture in North Korea. changes in climate and exchange relations identified in the process of forming and spreading the 'metal civilization', represented by the Mandolin-shaped Bronze Daggers culture, are noted as factors that cause cultural change. In particular, the climate cold in Northeast Asia is drawing attention as a breakthrough in the formation of the Mandolin-shaped Bronze Daggers culture and a change to the Slender Bronze Daggers culture. In the North Korean region, the regional characteristics of the South and the North are confirmed based on the Cheongcheon River, respectively, and the regional characteristics of the East and the West are highlighted based on the central mountainous region. Considering the sort and type of bronze artifacts and the ratio of alloy components, it can be seen that northwestern Korea and northeast Korea had a differentiated network or interaction due to their strong connection to Liaodong and Jilin, respectively. In the North Korean region, internal and external interactions increase, and exchange relations are further strengthened after the spread of the Zhengjiawazi Assemblage (6th~5th B.C.E). Due to the spread of the Zhengjiawazi Assemblage, the metal culture in North Korea changes from the Liaodong style to the Liaoxi (or Liaozhong) style, and accordingly, the exchange and ideological system of he Mandolin-shaped Bronze Daggers culture is also changed. The rapid increase of Liaozhong style’s bronze artifacts such as the bronze daggers and bronze mirrors is closely related to the growth of polity such as 'Gojoseon'.

Minding the gap between public administration curriculum and practice: The studio of public reasoning

It has always been a crucial question as to what kind of education should be provided to practitioners working at different levels of public administration, starting from the street level onwards, and what kind of interactions should be used to develop their competencies once in office. However, especially in the last 30 years, as we have entered a period of accelerating technological and institutional transformations, this issue has gained a dimension beyond the discussions on higher education and training for service. In addition to how public administration education will relate to practice as seen in traditional debates, new questions have emerged, such as how this engagement with practice can provide a perspective on institutional transformation, how those working in institutions can perceive their transformation processes more accurately, and ultimately, what kind of interaction can be achieved between those receiving public administration education and those working in public institutions. To answer these questions, an innovative model called “studio of public reasoning” was developed in 2009 for a university in public administration education in Turkey to create a platform for interaction with the external stakeholders of the university through an applied course. This Program has been implemented continuously for 15 years at the same university and more than 1000 students, about 100 public institutions of different scales and about 300 public administrators have benefited from the Program. In this paper, based on this experience, the gains of innovative teaching practices in public administration discipline in interacting with external stakeholders are critically evaluated through interviews with students, academics and administrators to assess whether alternatives are possible in establishing non-hierarchical external stakeholder interaction together with formal higher education for public administration.

The Analysis of Challenges and Opportunities in Integrated Village Government (IVG)

Following the implementation of the Law of Village, the resolution of village government issues proved to be a challenging endeavour. This paper presents a comprehensive systematic analysis to identify themes in village government studies. The primary objective is categorising the problems and possibilities village governments encounter. The research data utilised in this study is obtained from the Scopus Database, covering the period from 2009 to 2023. The data is subsequently analysed using the VOSviewer tool. The findings present five prominent themes and a total of 35 network elements of the governance of rural communities. These themes encompassed many aspects, such as healthcare, economic matters, conflicts, agricultural practices, and government initiatives. The study revealed that despite implementing the Law on Villages, the prevalence of intricate challenges in village government remains prominent. Scholars concur that they advocate for establishing collaborative efforts among stakeholders to delineate the sequential problem-solving steps. However, it is worth noting that rural communities often face challenges in embracing external interactions and adopting the urban commons model to establish an extensive network and facilitate multi-level growth. The findings serve as a foundation for future investigations on village government and a point of reference for more informed decision-making in governance practices. The limits were due to the exclusive use of publications from Scopus for analysis. Hence, conducting research employing a comparative approach and leveraging the Web of Science (WoS) database and other indexes are crucial to promoting the conceptual progress of village government study

E-governance and integration in the European union

The research here presented aims to analyze the global impact of e-governance in the European Union. It focuses on the long-term development of the European Union following the spillover effect described by Neofunctionalism integration theory. Therefore, it explores the potential of e-government fostering the European integration to a new level thanks to the new digital possibilities. New information and communication technologies can make a significant contribution to the achievement of good governance goals. This EU “e-governance” can make public management more efficient and more effective and attract the loyalty of the participants to the European project. This research outlines the main contributions of e-governance in Europe: improving government processes (e-administration); connecting citizens (e-citizens and e-services); and building external interactions (e-society). Case studies are used to show that e-governance is a current, not just future, reality for developing countries and the European Union. E-governance requires a concrete roadmap for its development and this chapter focuses on the main steps required to implement an effective e-governance within the European Union.

Directed brain interactions over time: A resting-state EEG comparison between schizophrenia and healthy individuals

Understanding the neurophysiological mechanisms of schizophrenia (SZ) is one of the challenges of neuroscience. Many anatomical and functional studies have pointed to problems in brain connectivity in SZ individuals. However, little is known about the relationships between specific brain regions and impairments in brain connectivity in SZ individuals. Herein we propose a new approach using time-varying graphs and the motif synchronization method to build dynamic brain functional networks (BFNs). Dynamic BFNs were constructed from resting-state electroencephalography (rs-EEG) of 14 schizophrenia (SZ) individuals and 14 healthy controls (HCs). BFNs were evaluated based on the percentage of synchronization importance between a pair of regions (considering external and internal interactions) over time. We found differences in the directed interaction between brain regions in SZ individuals compared to the control group. Our method revealed low bilaterally directed interactions between the temporal lobes in SZ individuals compared to HCs, indicating a potential link between altered brain connectivity and the characteristic symptoms of schizophrenia. From a clinical perspective, these results shed light on developing new therapeutic approaches targeting these specific neural interactions that are altered in individuals with SZ. This knowledge allows the application of better interventions focused on restoring or compensating for interrupted connectivity patterns.

Methodological approaches to the study of household financial sustainability

Introduction. The implementation of theoretical achievements of scientists in the study of household finances is preceded by the development of appropriate methodological approaches for conducting such research. However, a review of the literature has shown that scholars study mainly the methodology of household finances or their material embodiment - financial resources through the prism of using individual methods, without giving a general definition of the concept of methodology. Today, there is no consensus on the interpretation of the methodology of household finance research. This affects the overall development of this area of the financial system. This determines the relevance of developing methodological approaches to scientific knowledge of household financial sustainability The purpose of the paper is to continue existing research and develop proposals on methodological approaches to understanding the financial sustainability of households. During the study, analysis and synthesis were used as theoretical cognition of ensuring households’ financial sustainability. Results. The paper proposes dialectical, cognitive and institutional methodological approaches to the study of household financial sustainability. It is substantiated that the combination of such methodological approaches makes it possible to deepen the understanding of the concept of financial stability of households as a single whole, which is characterized by the interaction of external and internal. The process of external interaction takes place with the real economic and financial environment in which the household operates. As for the internal interaction, its essence is manifested through the peculiarities of the structure of the sustainability system, its composition and the interrelationships between the individual structural elements of the households’ financial activity. Conclusion. The proposed approaches make it possible to deepen the content of the concept of financial sustainability of households as a single whole, which is characterized by the interaction of external and internal. Taken together, the dialectical, cognitive, and institutional approaches discussed form the methodological basis for theoretical and practical research on the processes of ensuring household financial sustainability.