Objectives: This study evaluates the cultural and psychological preparation of university students to confront globalization's challenges by assessing the current state of such preparation from both faculty members’ and students’ perspectives. Background: University education is crucial for fostering higher-order thinking, talent development, and abilities that equip students to navigate the negative impacts of globalization. However, the extent of students' cultural and psychological readiness to face these challenges remains unclear. The study is aligned with the Sustainable Development Goals (SDGs), particularly Goal 4 (Quality Education) and Goal 8 (Decent Work and Economic Growth), focusing on building competencies for global engagement. Method: A survey method was employed to collect data from faculty members and students, examining psychological and cultural preparation, including self-esteem, socialization, and intercultural competence. Gender and academic discipline differences were also explored. Results and Discussion: The findings revealed generally low levels of both psychological and cultural preparation, with no significant differences between faculty and student views. Male students scored higher in psychological dimensions like self-esteem and socialization, while female students performed better in cultural preparation. Additionally, students from scientific disciplines exhibited higher levels of psychological and cultural readiness than those from other fields. Research Implications: The study emphasizes the need for targeted initiatives to enhance students' psychological and cultural preparedness, especially in non-scientific disciplines, to effectively confront globalization's challenges. Originality/Value: By identifying specific gaps in psychological and cultural readiness, this study provides practical recommendations for improving university education to better prepare students for global challenges.