This study aimed to assess the association between the waist-hip ratio and the extent of coronary artery disease by coronary angiography. A cross-sectional study was conducted in the Department of Cardiology, CPE Institute of Cardiology, Multan, from 09-Oct-2020 to 08-Apr-2021. One hundred fifty patients with CAD planned for coronary angiography (CAG) were included. Data regarding the patient's age, gender, and detailed clinical histories, such as co-morbid conditions such as hypertension, family history of CAD, diabetes mellitus, smoking, and waist-hip ratio, were collected for each patient. All patients underwent coronary angiography. In each patient, a Gensini score was calculated, and the mean value of the Gensini score was noted. The mean age of patients included in this study was 52.48±7.48 years. The mean waist-hip ratio was 0.83±0.10. The mean Gensini score was 36.68±6.84. There were 100 (66.6%) male and 50 (33.3%) female patients. Diabetes was found in 55 (36.6%), andhypertension in 81 (54.00%). Out of 150, 65 (43.3%) patients were smokers. A family history of CAD was found in 36 (24%). There was a significant correlation between the waist-hip ratio and the Gensini score, with a correlation coefficient of 0.679 and p-value <0.0001. Based on the results, it can be concluded that the waist-hip ratio is associated with the risk of coronary artery diseases, especially coronary artery disease.