Expressive Vocabulary Test Research Articles

Is There a Cognate Effect in Bilingual Children With Developmental Language Disorder?

Cognates, words in two languages that share form and meaning, can be used to support vocabulary development in bilingual children. Typically developing bilinguals have shown better performance on cognates versus noncognates. Of key interest is whether bilinguals with developmental language disorder (DLD) also show a cognate effect and, if so, which factors are related to their cognate performance. Thirty-five Spanish-English bilingual children (5-11 years old) with DLD completed the Expressive and Receptive One-Word Picture Vocabulary Tests, third edition, in English (EOW, ROW) to measure cognate performance. Test items were divided by difficulty level (easy, medium, and hard) and classified as cognates or noncognates using the Cross-Linguistic Overlap Scale for Phonology. On average, children showed clear and robust cognate effects on EOW across difficulty levels with medium-to-large effect sizes. Results on the ROW showed minimal effects that varied by difficulty. Individually, 80% of participants (28 of 35) demonstrated a cognate effect in EOW, whereas only 31% (11 of 35) showed an effect in ROW. A cognate effect in ROW was positively correlated with age and English proficiency, whereas no factors correlated with the EOW cognate effect. Bilingual children with DLD show higher performance on cognates than noncognates, at least in expressive vocabulary. Participants who did show a receptive cognate effect tended to be older and have higher English proficiency. Further investigation is needed to identify factors underlying cognate performance in order to tailor intervention strategies that promote bilingual vocabulary development.

Pediatric Sleep Apnea: The Overnight Electroencephalogram as a Phenotypic Biomarker.

Pediatric obstructive sleep apnea (OSA) is a prevalent disorder that disrupts sleep and is associated with neurocognitive and behavioral negative consequences, potentially hampering the development of children for years. However, its relationships with sleep electroencephalogram (EEG) have been scarcely investigated. Here, our main objective was to characterize the overnight EEG of OSA-affected children and its putative relationships with polysomnographic measures and cognitive functions. A two-step analysis involving 294 children (176 controls, 57% males, age range: 5–9 years) was conducted for this purpose. First, the activity and irregularity of overnight EEG spectrum were characterized in the typical frequency bands by means of relative spectral power and spectral entropy, respectively: δ1 (0.1–2 Hz), δ2 (2–4 Hz), θ (4–8 Hz), α (8–13 Hz), σ (10–16 Hz), β1 (13–19 Hz), β2 (19–30 Hz), and γ (30–70 Hz). Then, a correlation network analysis was conducted to evaluate relationships between them, six polysomnography variables (apnea–hypopnea index, respiratory arousal index, spontaneous arousal index, overnight minimum blood oxygen saturation, wake time after sleep onset, and sleep efficiency), and six cognitive scores (differential ability scales, Peabody picture vocabulary test, expressive vocabulary test, design copying, phonological processing, and tower test). We found that as the severity of the disease increases, OSA broadly affects sleep EEG to the point that the information from the different frequency bands becomes more similar, regardless of activity or irregularity. EEG activity and irregularity information from the most severely affected children were significantly associated with polysomnographic variables, which were coherent with both micro and macro sleep disruptions. We hypothesize that the EEG changes caused by OSA could be related to the occurrence of respiratory-related arousals, as well as thalamic inhibition in the slow oscillation generation due to increases in arousal levels aimed at recovery from respiratory events. Furthermore, relationships between sleep EEG and cognitive scores emerged regarding language, visual–spatial processing, and executive function with pronounced associations found with EEG irregularity in δ1 (Peabody picture vocabulary test and expressive vocabulary test maximum absolute correlations 0.61 and 0.54) and β2 (phonological processing, 0.74; design copying, 0.65; and Tow 0.52). Our results show that overnight EEG informs both sleep alterations and cognitive effects of pediatric OSA. Moreover, EEG irregularity provides new information that complements and expands the classic EEG activity analysis. These findings lay the foundation for the use of sleep EEG to assess cognitive changes in pediatric OSA.

Maternal responsiveness and directiveness in speech to 2-year-olds: Relationships with children’s concurrent and later vocabulary

This study investigated responsive and directive speech from 60 Finnish mothers to their 2-year-old children, as well as correlations with concurrent and later vocabulary. Possible gender differences with regard to both maternal speech and children’s vocabulary skills were considered. There were no gender differences in maternal utterance frequencies or in maternal utterance types. Girls scored statistically significantly higher in receptive and expressive vocabulary tests at 24, 30 and 36 months. The effect sizes were large. Maternal Other Utterances (fillers like yes, oh, umm) were correlated with children’s concurrent receptive vocabulary. However, there was no relationship between Other Utterances and children’s later vocabulary after controlling for vocabulary size at 24 months. This association may reflect an attempt by mothers to elicit speech from more linguistically advanced children. Furthermore, mothers’ Intrusive Directives towards 2-year-olds correlated negatively with receptive vocabulary at 30 months, particularly for boys. Surprisingly, Intrusive Attentional Directives correlated positively with expressive vocabulary in the group of 30-month-old girls. The results of this study demonstrate relationships between maternal verbal interactional style and both concurrent and future child vocabulary.

Intraword Variability in French-Speaking Monolingual and Bilingual Children.

Purpose This study examines intraword variability in 40 typically developing French-speaking monolingual and bilingual children, aged 2;6-4;8 (years;months). Specifically, it measures rate of intraword variability and investigates which factors best account for it. They include child-specific ones such as age, expressive vocabulary, gender, bilingual status, and speech sound production ability, and word-specific factors, such as phonological complexity (including number of syllables), phonological neighborhood density (PND), and word frequency. Method A variability test was developed, consisting of 25 words, which differed in terms of phonological complexity, PND, and word frequency. Children produced three exemplars of each word during a single session, and productions of words were coded as variable or not variable. In addition, children were administered an expressive vocabulary test and two tests tapping speech motor ability (oral motor assessment and diadochokinetic test). Speech sound ability was also assessed by measuring percent consonants correct on all words produced by the children during the session. Data were entered into a binomial logistic regression. Results Average intraword variability was 29% across all children. Several factors were found to predict intraword variability including age, gender, bilingual status, speech sound production ability, phonological complexity, and PND. Conclusions Intraword variability was found to be lower in French than what has been reported in English, consistent with phonological differences between French and English. Our findings support those of other investigators in indicating that the factors influencing intraword variability are multiple and reflect sources at various levels in the speech processing system.

Identification of Word Retrieval Difficulties in the Normally Aging Population

Purpose This study examined variations in performance on different verbal tasks completed by typically aging, non-neurologically impaired adults who self-identified as either having or not having word retrieval difficulties that frequently affected their lifestyle. Method Fifty-seven adults aged 54–71 years, who were recruited based on case history responses that indicated the presence or absence of word retrieval difficulties, completed two standardized, norm-referenced language tests, two naming tasks, and three verbal fluency measures. Results Although scores on standardized language tests fell within normal limits for all of the participants, significant differences between those with and those without self-reported word retrieval difficulties were found on the Expressive Vocabulary Test–Second Edition as well as on tasks of naming members of categories and producing procedural narratives. A significantly greater percentage of disfluencies in procedural narratives were found in the group that reported word retrieval difficulties. This fluency indicator was the only factor that was predictive of word retrieval difficulties. Conclusions Many studies have examined the differences in word retrieval in older versus younger populations or in persons with aphasia versus persons without aphasia, but they have not offered definitive pictures of the differences between those with and those without word retrieval difficulties in the normally aging population who have otherwise normal language. This study identified three tasks that appear to be sensitive to the word-finding difficulties experienced by some adults.

Validation of The Reading House and Association With Cortical Thickness.

The American Academy of Pediatrics recommends literacy and school readiness promotion during well visits. The Reading House (TRH) is a children's book-based screener of emergent literacy skills in preschool-aged children. Vocabulary, rhyming, and rapid naming are core emergent skills, and reading abilities are associated with thicker cortex in the left hemisphere. Our objective was to expand validity of TRH relative to these skills and explore association with cortical thickness. Healthy preschool-aged children completed MRI including a T1-weighted anatomic scan. Before MRI, TRH and assessments of rapid naming (Comprehensive Test of Phonological Processing, Second Edition), rhyming (Pre-Reading Inventory of Phonological Awareness), vocabulary (Expressive Vocabulary Test, Second Edition), and emergent literacy (Get Ready to Read!) were administered. Analyses included Spearman-ρ correlations (r ρ) accounting for age, sex, and socioeconomic status (SES). MRI analyses involved whole-brain measures of cortical thickness relative to TRH scores, accounting for covariates. Seventy children completed assessments (36-63 months old; 36 female) and 52 completed MRI (37-63 months; 29 female). TRH scores were positively correlated with Comprehensive Test of Phonological Processing, Second Edition (r ρ = 0.61), Expressive Vocabulary Test, Second Edition (r ρ = 0.54), Get Ready to Read! (r ρ = 0.87), and Pre-Reading Inventory of Phonological Awareness scores (r ρ = 0.64; all P < .001). These correlations remained statistically significant across age, sex, and SES groups. TRH scores were correlated with greater thickness in left-sided language and visual cortex (P-family-wise error <.05), which were similar for higher SES yet more bilateral and frontal for low SES, reflecting a less mature pattern (P-family-wise error <.10). These findings expand validation evidence for TRH as a screening tool for preschool-aged children, including associations with emergent skills and cortical thickness, and suggest important differences related to SES.

Cognitive achievements in school-age children born following assisted reproductive technology treatments: A prospective study

BackgroundWhile assisted reproductive technology is increasingly prevalent, there is concern amid conflicting findings reported regarding the long-term outcomes of children born following these treatments. The aim of this research was to investigate aspects of cognitive development in early school-age Israeli children born following assisted reproductive technology (ART) treatments, compared to those spontaneously conceived (SC). MethodThis prospective follow-up study was based on an Israeli cohort recruited from June 2006 to December 2008, that included 561 women whose pregnancies were achieved by ART treatments and 600 women whose pregnancies were SC. When the children were 7–8 years old, 759 of their mothers were interviewed by telephone, and 294 were came for developmental assessment. The examination included: Kaufman Brief Intelligence Test; Kaufman Assessment Battery for Children (arithmetic only); Test of Everyday Attention for Children; Beery-Buktenica Developmental Test of Visual-Motor Integration and Supplemental Test for Visual Perception; Rey-Osterrieth Complex Figure Test; Aleph-ad-Tav Hebrew reading and writing; Tavor Picture Naming Expressive Vocabulary Test. Multivariable analyses were adjusted for maternal years of education (≤12, 13+) at child's birth and child's sex. ResultsCognitive function, visual-motor ability, attention, and verbal skills of children born after ART treatments were similar to those of SC children, upon both univariate and multivariable analysis. Conclusion and implicationsNo significant differences were found between the ART and SC groups on any of the measures examined. This finding offers couples seeking ART treatments improved information regarding child development during the important and formative school years. What this paper addsIncreasing rates of ART treatments arouse concern about long-term outcomes for offspring, and conflicting findings have been reported with respect to the skills necessary to their academic success. This prospective follow-up study compared school-age children born following ART with spontaneously-conceived children. Children were examined by developmental psychologists, and cognitive function, visual-motor, attention, verbal, and performance skills were similar in both groups.

Cultural adaptation of the Expressive One-Word Picture Vocabulary Test, 4th edition (EOWPVT-4), for Brazilian Portuguese speakers.

To present a brief report of the first steps that involved the process of the cultural translation and adaptation of the Expressive One-Word Picture Vocabulary Test, fourth edition to Brazilian Portuguese (BP). The process of translation and adaptation of this instrument was performed in the following steps: (1) translation of the original text (English) to Brazilian Portuguese (target culture) by two different sworn translators oriented towards our research goal; (2) parity analysis between both translations and design, by a group of experts, of a synthesis version; (3) back translation of the synthesis version by two other sworn translators who did not participate in step 1; and (4) Comparison between back-translation and the original version made by a group of specialists, thus shaping the pre-final adapted version of the EOWPVT-4. In the Brazilian version, the number of items from the original version was maintained and the cultural adaptation of the EOWPVT-4 to BP followed the steps recommended in the literature besides considering the differences in the socio-cultural context, showing no significant discrepancies regarding semantic equivalence. Relevant adaptations (e.g., items not representative within the Brazilian culture) were required during this process so that the instrument could be used with the same methodological rigor as the original instrument. The process of cultural adaptation of this instrument indicated that there was theoretical, semantic, idiomatic and cultural equivalence with the original version in English.

L2 vocabulary acquisition of early sequentially bilingual children with TD and DLD affected differently by exposure and age of onset.

Language exposure is known to be a key factor influencing bilingual vocabulary development in typically developing (TD) children. There is, however, a lack of knowledge in terms of exposure effects in children with developmental language disorder (DLD) and, especially, in interaction with age of onset (AoO) of second language acquisition. In the Helsinki longitudinal SLI study (HelSLI), we investigated the receptive and expressive second language (L2) vocabulary performance and cross-sectional vocabulary development of sequentially bilingual children with TD and DLD in order to resolve whether the groups could be differentiated based on their vocabulary performance. More importantly, we examined the effects of AoO and exposure in the vocabulary performance of these two bilingual groups. A total of 70 children with DLD from a hospital clinic and 82 with TD from kindergartens were recruited. Children were 3-7 years old with different AoOs for the L2 and varying degrees of language exposure. Multiple regression analysis was used to compare the groups in two receptive and three expressive vocabulary tests while considering the effects of AoO and language exposure. Children with TD outperformed children with DLD in both receptive and expressive vocabulary measures. Exposure predicted vocabulary but AoO did not. The effect of exposure was different in TD and DLD groups in receptive but not in expressive vocabulary. Additionally, the interaction of exposure and AoO was found for receptive vocabulary, but similarly in both groups. With increasing exposure, a difference in performance between the groups became more notable in receptive vocabulary compared with the expressive vocabulary. Bilingual children with TD and DLD can be differentiated by using L2 vocabulary tests when exposure is taken into consideration. Non-significant AoO effects in 3-7 year olds suggest flexibility in terms of when to start L2 immersion. However, exposure is important, and especially children with DLD would need a substantial amount of it relative to their TD peers, so that they would not fall even further behind over time. Differences in benefiting from exposure in receptive mode might offer clinicians and kindergarten personnel an insight for evaluating challenges in bilingual development. Severe challenges in vocabulary development in the DLD group also call for both individually targeted small-group activities for learning words as well as strategies for strengthening vocabulary in various environments and everyday life situations. What this paper adds What is already known on the subject Language exposure is often found to explain more of the variation compared with AoO in early L2 vocabulary. On the other hand, it has been suggested by some researchers, but not all, that AoO effects would be found. Exposure and AoO might also interact differently depending on the task and whether the development is typical or disordered. Contrary to the clinical observation, diagnostic value of receptive vocabulary has often been questioned. What this paper adds to existing knowledge This study indicates that receptive vocabulary might be useful in differentiating bilingual TD and DLD. Language exposure effects differ between TD and DLD groups, but depending on task. Lower performance, but also slower cross-sectional development, is found in receptive vocabulary for children with DLD. Interaction between language exposure and AoO stresses the importance of taking both into consideration when studying bilingual development. What are the potential or actual clinical implications of this work? L2 vocabulary tests can be used in differentiating bilingual children with TD and DLD when exposure is taken into consideration. Difficulties using exposure and, hence, slower development in children with DLD suggest that especially receptive vocabulary might be diagnostic by the accumulating exposure. Investing in ways of supporting vocabulary development through small-group activities and in everyday situations of bilingual children at risk of DLD is highly recommended. This is important to prevent them from incrementally falling further behind their TD peers over time. A limited AoO effect suggests that families have more flexibility in terms of when to place their child in L2 immersion in their early years.

아버지와 어머니의 문해 신념 및 문해 상호작용이 유아의 어휘력에 미치는 영향

This study focused on 120 children age four-five and their parents examining the parents’ literacy beliefs and literacy interaction and how the two variables affect their children’s vocabulary. The subjects were 120 children and 120 parents in Seoul, Gyeonggi Province and Sejong City.BR ‘Parental literacy beliefs’ and ‘literacy interaction of parents’ were measured using questionnaires by Lee and Kim (2011) and Son and Kim (2012). To estimate the vocabulary of the children, this study used the Receptive Expressive Vocabulary Test: REVT (Kim, Hong, Kim, Jang, & Lee, 2009). A researcher visited institutes and conducted the procedure individually. The data was analyzed using the t-test, Pearson’s correlation, and the multiple regression.BR The results of this study are as follow. First, there was a statistically significant difference between each parent’s literacy beliefs. There was also a statistically significant difference between each parent’s literacy interaction. Second, there were significant correlations between each parent’s literacy beliefs and literacy interactions. Interestingly, The higher the fathers’ beliefs in literacy, the more openly they interacted, and the more they read and interacted with pictures. Additionally, the higher the mothers’ beliefs, the more open interaction with picture-book reading interaction and the more directive interaction. Third, we examined the effects of each parent’s literacy beliefs and literacy interactions on children’s vocabulary skills. The father’s ‘parental role’ and the mother’s ‘parental reading influence’ showed significant influence over the vocabulary skills of the children. Also, the children’s vocabulary skills and father’s ‘picture-book reading interaction showed significant influence. In conclusion, the interaction between each parent’s literacy beliefs and father’s literacy interaction influences their children’s vocabulary skills.

Associations among exposure to television or video, language development, and school achievement in childhood: a prospective birth cohort study.

Exposure to electronic media, which begins in early childhood, has been gradually increasing. This study investigated the associations between time watching television or video (TV time), children's language development, and school achievement using a large prospective design. The participants underwent annual assessment from birth (T1; 5.5months) to T8 (87.9months). We used a parental questionnaire to evaluate TV time annually from T3 (2.2years) to T8 (7.3years), by the item asking "How many hours does your child usually spend a day watching TV or videos?". Children were grouped by TV time using group-based trajectory analysis. Among 2150 participants, 1087 were included in the final analysis. The Korean version of the Denver II and the Korean-Ages and Stages questionnaires were administered to evaluate early childhood development (T1 to T3). The Receptive and Expressive Vocabulary Test was used to assess children's language development at T8. Questionnaires completed by both parents and teachers were used to evaluate school achievement at T8. Participants were divided into "Low Descending" (LD), "Medium Flat" (MF), "High Ascending" (HA), and "Extremely High Descending" (XHD) groups. Early language development at T1 and T2 did not significantly differ among all groups. However, language development at T3 and T8, and school achievement at T8 differed significantly, and were the highest in LD and lowest in HA. We found a negative association between greater TV time and children's language and cognitive development. Thus, unchecked TV exposure could be detrimental to childhood cognitive development.

The Hearing and Talking Scale (HATS): Development and validation with young Aboriginal and Torres Strait Islander children in urban and remote settings in Australia

ABSTRACT Many Aboriginal and Torres Strait Islander children are affected by chronic middle ear infection or otitis media from infancy that has a negative impact on development of listening and communication skills. Deficits in these skills are often not detected until school-age when the opportunity for early intervention is lost. Primary health and early childhood workers need screening tools to assist them with detecting the problem early, but there is a scarcity of tools. This study reports the development and validation of a screening tool for detecting communication problems in young Aboriginal and Torres Strait Islander children. The tool, called the Hearing and Talking Scale (HATS), relies on a systematic use of parent observations of communication behaviours of their children in everyday situations. Developed by using a co-design approach, the HATS is culturally and linguistically appropriate for use with parents/carers of young children by front-line workers not trained in speech-language pathology. We validated the HATS by comparing the HATS score of 68 children (46 Indigenous and 22 non-Indigenous children) with their performance in standardised assessments. The accuracy of the HATS was 80% and 81% when compared to the ASQ-TRAK and the Expressive Vocabulary Test respectively. The HATS takes 5 minutes to administer, and is easy to score and interpret. It can be used as part of a standard ear and hearing health check for young children to support early detection so that those with problems can be referred for specialist diagnosis and treatment at a young age.

Associations between breastfeeding and cognitive function in children from early childhood to school age: a prospective birth cohort study

BackgroundDespite evidences of breastfeeding for preventing acute physical illnesses in infants, the evidence for the association between breastfeeding and long-term cognitive development is not yet convincing.MethodsThe data of nationwide representative sample of 1752 children born between 2008 and 2009 in Korea were prospectively assessed from the fetal period to examine the benefits of breastfeeding and cognitive development. Breastfeeding duration was prospectively assessed by parents. The Korean Ages and Stages Questionnaire and the Korean version of Denver II were used to assess early development annually from 5.5 to 26.2 months of age. Language development at 3 years of age was assessed with Receptive and Expressive Vocabulary Tests. Cognitive function at 8 years of age was assessed using multifactorial intelligence test.ResultsIn the analysis of categorical variables, children who were breastfed for > 1 and ≤ 3 months displayed significantly higher odds ratios for delayed development assessed with Korean Ages and Stages Questionnaire at 14.1 months than those breastfed for > 3 and ≤ 6 months (OR = 2.21; 95% CI: 1.08, 4.50), but no significant differences in other rounds of assessments. In the analysis with continuous variables, there were significant differences among six groups of breastfeeding duration in communication (F = 3.72; p < 0.002) and problem solving (F = 3.09; p < 0.009) at 14.1 months, expressive language (F = 3.74; p = 0.002) at 3 years, and calculation (F = 2.43; p < 0.033) at 8 years. When analyzed by two groups, children breastfed for > 3 months scored significantly higher on the communication (F = 17.71; p < 0.001) and problem-solving (F = 11.26; p < 0.001) subscales at 14.1 months, and expressive language (F = 12.85; p < 0.001) at 3 years, and vocabulary (F = 6.78; p = 0.009) and language inference (F = 5.62; p = 0.018) at 8 years, compared to children breastfed for 3 months or less.ConclusionWe found that cognitive development was improved in children that were breastfed for > 3 months. Although these results are supported by previous studies, it is important to note that other factors were reported as larger determinants of cognitive development than breastfeeding. Future studies that examine the underlying mechanism for the association between breastfeeding and cognitive development are warranted.

A Phase II Randomized Clinical Trial of the Safety and Efficacy of Intravenous Umbilical Cord Blood Infusion for Treatment of Children with Autism Spectrum Disorder

To evaluate whether umbilical cord blood (CB) infusion is safe and associated with improved social and communication abilities in children with autism spectrum disorder (ASD). This prospective, randomized, placebo-controlled, double-blind study included 180 children with ASD, aged 2-7years, who received a single intravenous autologous (n=56) or allogeneic (n=63) CB infusion vs placebo (n=61) and were evaluated at 6months postinfusion. CB infusion was safe and well tolerated. Analysis of the entire sample showed no evidence that CB was associated with improvements in the primary outcome, social communication (Vineland Adaptive Behavior Scales-3 [VABS-3] Socialization Domain), or the secondary outcomes, autism symptoms (Pervasive Developmental Disorder Behavior Inventory) and vocabulary (Expressive One-Word Picture Vocabulary Test). There was also no overall evidence of differential effects by type of CB infused. In a subanalysis of children without intellectual disability (ID), allogeneic, but not autologous, CB was associated with improvement in a larger percentage of children on the clinician-rated Clinical Global Impression-Improvement scale, but the OR for improvement was not significant. Children without ID treated with CB showed significant improvements in communication skills (VABS-3 Communication Domain), and exploratory measures including attention to toys and sustained attention (eye-tracking) and increased alpha and beta electroencephalographic power. Overall, a single infusion of CB was not associated with improved socialization skills or reduced autism symptoms. More research is warranted to determine whether CB infusion is an effective treatment for some children with ASD.

Bilingualism and Processing Speed in Typically Developing Children and Children With Developmental Language Disorder.

Purpose The aim of the current study was to investigate whether dual language experience modulates processing speed in typically developing (TD) children and in children with developmental language disorder (DLD). We also examined whether processing speed predicted vocabulary and sentence-level abilities in receptive and expressive modalities. Method We examined processing speed in monolingual and bilingual school-age children (ages 8-12 years) with and without DLD. TD children (35 monolinguals, 24 bilinguals) and children with DLD (17 monolinguals, 10 bilinguals) completed a visual choice reaction time task. The Clinical Evaluation of Language Fundamentals, the Peabody Picture Vocabulary Test, and the Expressive Vocabulary Test were used as language measures. Results The children with DLD exhibited slower response times relative to TD children. Response time was not modified by bilingual experience, neither in children with typical development nor children with DLD. Also, we found that faster processing speed was related to higher language abilities, but this relationship was not significant when socioeconomic status was controlled for. The magnitude of the association did not differ between the monolingual and bilingual groups across the language measures. Conclusions Slower processing speed is related to lower language abilities in children. Processing speed is minimally influenced by dual language experience, at least within this age range. Supplemental Material https://doi.org/10.23641/asha.12210311.

Neuroregenerative evidences demonstrated by diverse MRI analysis in cerebral palsy children who showed significant clinical improvement following repeated G-CSF injection

Background & Aim We tried to confirm the structural changes of magnetic resonance imaging (MRI) and their relation with clinical improvement in cerebral palsy (CP) children who treated with repeated granulocyte colony-stimulating factor (G-CSF) injection. Methods, Results & Conclusion We performed a phase II, randomized placebo controlled clinical trials to reveal clinical improvement after repeated G-CSF injection. Forty-four children with CP were enrolled, and their ages were 2-10 years old. G-CSF (5μg/kg) was administered for 5 days subcutaneously every 3 months during 18 months. We evaluated motor and cognitive functions along with MRI study. To compare the structural changes of MRI between treated and placebo groups, we analyzed the white matter integrity in region of interest as well as in functional networks. We also analyzed the subcortical volume and cortical thickness in MRI. The treated group showed significantly greater increases in cognitive function scores noted in picture memory subtest and expressive vocabulary test as well as increasing tendency in visual motor integrity test. Diverse neuroimaging analysis revealed decrease of mean diffusivity (MD) of region of superior longitudinal fasciculus and cingulum, and also decrease of MD of sensori-motor network and language network. Increase of cortical thickness of left inferior frontal gyrus was also noted. These changes suggested structural improvement in circuit of sensori-motor information and motor language area, and were compatible with the improvement of picture memory and expressive language in cognitive function tests. By the same method of analysis, the structural improvement in the area of cerebral cortex and basal ganglia were noted, which suggest the improvement of visual motor integration in cognitive function tests. The increase of subcortical volume of nucleus accumbens was also noted, suggesting improvement of socialization. In conclusion, we demonstrated the neuroregenerative evidences by diverse MRI analysis as well as the improvement of cognitive functions after repeated G-CSF injection in children with CP.

4～6세 일반아동 및 언어발달지연 아동의 음운인식 및 음운처리 능력이 언어 능력에 미치는 영향*

Phonological awareness is a metalinguistic awareness ability of phonology and is known to predict language skills, such as reading and vocabulary skills. The purpose of this study was to investigate the relationship between phonological awareness, phonological processing, and language skills in 4- to 6-years-old typically developing (TD) children and children with language delay (LD). A total of 32 children (TD=18, LD=15) participated in this study. They performed a phonological awareness task consisting of counting, deletion, and discrimination at syllable level. Nonword Repetition, Digit Backward, Receptive &amp; Expressive Vocabulary Test, and Grammaticality Judgment Task were performed to analyze the correlation between phonological awareness, phonological processing, and language ability. A multiple stepwise regression analysis was performed to examine the phonological awareness subtasks that predict language ability. In the TD group, the syllable categorization task significantly predicted the receptive vocabulary and the performance of the Grammaticality Judgment Task. The LD group showed that the syllable counting task significantly predicted the receptive vocabulary, the expressive vocabulary, and the performance of the Grammaticality Judgment Task. The results showed that the phonological awareness performance was significantly different between the two groups. Further, correlation analysis and regression analysis showed different results for each group. The result of the phonological awareness performance predicted the language ability of each group significantly, suggesting the importance of the meta-linguistic awareness ability of phonology.

A novel, composite measure of screen-based media use in young children (ScreenQ) and associations with parenting practices and cognitive abilities.

Screen-based media use is prevalent in children and is associated with health risks. American Academy of Pediatrics (AAP) recommendations involve access to screens, frequency, content, and co-viewing. The aim of this study was to test the ScreenQ, a composite measure of screen-based media use. ScreenQ is a 15-item parent report measure reflecting AAP recommendations. Range is 0-26, higher scores reflecting greater non-adherence. With no "gold standard" available, four validated measures of skills and parenting practices cited as influenced by overuse were applied as the external criteria, including expressive language, speed of processing, emergent literacy, and cognitive stimulation at home. Psychometric analyses involved Rasch methods and Spearman's ρ correlations. Sixty-nine families were administered ScreenQ. Child age ranged from 36 to 63 months old (52 ± 8; 35 girls). Mean ScreenQ score was 9.6 (±5.0; 1-22). Psychometric properties were strong (rCo-α = 0.74). ScreenQ scores were negatively correlated with CTOPP-2 (Comprehensive Test of Phonological Processing, Second Edition) (rρ = -0.57), EVT-2 (Expressive Vocabulary Test, Second Edition) (rρ = -0.45), GRTR (Get Ready to Read!) (rρ = -0.30) and StimQ-P (rρ = -0.42) scores (all p ≤ 0.01). ScreenQ shows potential as a composite measure of screen-based media use in young children in the context of AAP recommendations. ScreenQ scores were correlated with lower executive, language and literacy skills, and less stimulating home cognitive environment.

Lexical diversity and lexical skills in children who stutter

PurposeNumerous “small N” studies of language ability in children who stutter have produced differing conclusions. We combined test and spontaneous language data from a large cohort of children who stutter (CWS) and typically fluent peers, gathered from independent laboratories across the US, to appraise a variety of lexical measures. MethodStandardized receptive and expressive vocabulary test data and spontaneous language samples from 99 pairs of CWS (ages 25–100 months), and age-, gender-, and SES-matched children who do not stutter (CWNS) were compared. Language sample transcripts were analyzed with four measures of lexical diversity. Correlations between lexical diversity measures and expressive vocabulary scores were also calculated. ResultsOn standardized tests of both receptive and expressive vocabulary, there were significant differences between CWS and CWNS. In contrast, on spontaneous language measures of lexical diversity, CWS did not differ in their lexical diversity, across analyses, compared to CWNS. Three of the four lexical diversity analyses, MATTR, VocD, and NDW, were significantly correlated with each other. ConclusionsWe were able to confirm prior findings of relative disadvantage on standardized vocabulary tests for a very large sample of well-matched CWS. However, spontaneous language measures of lexical diversity did not distinguish the groups. This relative weakness in CWS may emerge from task differences: CWS are free to encode their own spontaneous utterances but must comply with explicit lexical prompts in standardized testing situations.

Vocabulary assessment in Brazilian children: a systematic review with three instruments.

To investigate, through a systematic review, how three assessment instruments for children's vocabulary (Test of Childhood language ABFW, Expressive Vocabulary Test - EVT, and Peabody Picture Vocabulary Test - PPVT) have been used in Brazilian research, verifying its purposes of uses and the main results of the researches. This review was organized in three studies. Study 1 referred to the process of a priori search and Study 2 referred to the a posteriori search. We searched for three Brazilian's database (CAPES, SciELO, and PePSIC). For Study 1, we selected empirical studies containing research data with one of the three-targeted tests, using typically developing school children (7 to 10 years old). For Study 2, we enlarged the age range for pre-school and extended the search to non-typically developing children. The selected articles were fully read and synthesized in a table containing the study's aims, the age range of the sample, instrument, research design, main results, and journal. We found out 24 articles, most of which from the speech-language therapy area. The results indicated the predominance of cross-sectional and observational studies, aiming to delineate the cognitive profile of children with some developmental disturbance, with or without control groups. None of the researches conducted a psychometric inquiry of the instruments. In Brazil, it is necessary to carry out research focusing on the psychometric inquiry of instruments for evaluating the vocabulary in pre-school and school-age children.