Quantum-based sensing and measurement technology is a disruptive technology that can realize fine detection of the gravity and magnetic fields in deep Earth, and it has become a key development direction for geophysical exploration equipment worldwide. This study focuses on the frontier technologies for the quantum-based high-precision measurement of Earth’s gravity and magnetic fields, summarizes the development status of quantum-based geophysical exploration equipment, and analyzes demand for the superconducting quantum-based electromagnetic detection system, magnetic vector gradient detection system, superconducting gravity detection system, and cold-atom absolute-gravity exploration system during deep resource exploration. Moreover, the international trend of quantum-based high-precision measurement technology as well as the development opportunities and challenges in this field are analyzed. To improve the core technology research, complete localization, and exploration application of quantum-based geophysical exploration equipment in China, we propose the development goals, technical system, key tasks, and strategic planning for a new generation of quantum-based high-precision deep geophysical exploration equipment. This aims to achieve breakthroughs in superconducting quantum chips and high-sensitivity sensors, establish a collaboration model for the independent development of China’s quantum-based geophysical exploration equipment, promote the high-quality development of deep exploration equipment, and provide strategic support for solving major problems associated with deep mineral resource exploration and revealing of Earth’s deep structure.