Background and Aim: The Wild Animal Screening Center in Espírito Santo State (CETAS-ES), Brazil, treats wildlife from trafficking and illegal trade, accidents, captivity, and rescue from out of their habitat. The present study described the trends in wildlife admission to the CETAS-ES over the past 10 years and discussed the impact of animal exploitation. Materials and Methods: This descriptive study used a database provided by the CETAS-ES with data on animals admitted between 2011 and 2021, including admission year, origin, place of captivity, taxonomic category, sex, life stage, and health status. Results: Over 10 years, 23,176 animals were admitted, with an annual average of 2,106 admissions. Seizing was the most common origin (60.39%), followed by rescues/collections (22.60%) and voluntary delivery (11.7%), whereas 5.3% had unidentified origins. Birds were the most frequently admitted animals (80.6%) and were predominant among those seized (97.5%), rescued/collected (46.7%), and voluntarily delivered (73.2%). Mammals represented 45.0% of rescues/collections and reptiles represented 19.0% of voluntary deliveries. Conclusion: The admissions reveal a vulnerable scenario for wildlife in the Brazilian Atlantic Rainforest of Espírito Santo State, mainly affecting birds. Seizing was a common occurrence over the decade, reinforcing the necessity of actions to prevent wildlife trafficking and illegal trade. Keywords: Atlantic Rainforest, biodiversity, fauna, wildlife trade.