Mathematical models of nonlinear cross diffusion are described by a system of nonlinear partial parabolic equations associated with nonlinear boundary conditions. Explicit analytical solutions of such nonlinearly coupled systems of partial differential equations are rarely existed and thus, several numerical methods have been applied to obtain approximate solutions. In this paper, based on a self-similar analysis and the method of standard equations, the qualitative properties of a nonlinear cross-diffusion system with nonlocal boundary conditions are studied. We are constructed various self-similar solutions to the cross diffusion problem for the case of slow diffusion. It is proved that for certain values of the numerical parameters of the nonlinear cross-diffusion system of parabolic equations coupled via nonlinear boundary conditions, they may not have global solutions in time. Based on a self-similar analysis and the comparison principle, the critical exponent of the Fujita type and the critical exponent of global solvability are established. Using the comparison theorem, upper bounds for global solutions and lower bounds for blow-up solutions are obtained.