Expiratory Volume In First Second Research Articles

Association between lung function and bone mineral density in children and adolescents: Insights from the NHANES.

Bone development and lung function are integral to child and adolescent health. Both influence an individual's overall well-being and potentially affect long-term health. Utilizing a comprehensive dataset from the National Health and Nutrition Examination Survey, this study aims to elucidate the relationship between lung function and bone mineral density (BMD) in a representative sample of children and adolescents. The analysis covered 3410 participants aged 8 to 19 years. We employed weighted multivariate linear regression and restricted cubic spline curve visualizations to explore the intricate association between lung function metrics, particularly first-second expiratory volume 1 second/forced vital capacity ratio, and lumbar BMD. Our data indicated a positive association between lung function and lumbar BMD in children and adolescents. Specifically, higher lung function metrics were linked with increased lumbar BMD. This association was more pronounced in younger participants or those with a lower body mass index. A significant positive relationship exists between lung function and BMD in the pediatric population. Recognizing this association is crucial for holistic health strategies for children and adolescents. This study underscores the need for integrated health monitoring during formative years, which can influence health trajectories as these individuals transition to adulthood.

Pulmonary function tests in Petrol pump workers in Karad town

Objectives: Polluted environment at petrol pumps is likely to have adverse effects on health of workers. Petrol filling workers as well as office workers at petrol pumps are likely to have adverse effects on lung function. We wanted to study the actual fact. Methods: Pulmonary function tests were studied in petrol pump workers in Karad city and around. Petrol filling workers (direct exposure group, 48) and petrol pump office workers (indirect exposure group, 12) were included in study. Control group (50) of age matched healthy paramedical workers from KIMS, University was included. Approval from Institutional Ethical Committee was obtained. Informed written consent was taken from each participant. Spirometric lung function test were carried out in department of Physiology. Pulmonary function parameters included were FVC (Forced Vital Capacity), FEV1 (Forced Expiratory Volume in First second of FVC), FEV1% (FEV1 as % of FVC), PEFR (Peak Expiratory Flow Rate in liters/sec), FEF25-75% (Forced Expiratory Flow Rate during 25 to 75 % of expiration), FEF 0.2-1.2 (Forced Expiratory Flow between 0.2 -1.2 liters of expiration) and MVV (Maximum Voluntary Ventilation). After computing mean and SD of each parameter group comparison was done by using paired t test and ANOVA. Results: Impairment of lung function (Predominantly restrictive type) was found in both the study groups compared to controls. Conclusions: Exposure to polluted air and fumes of petrol/diesel causes lung function derangement in petrol pump workers.

Pulmonary Function Tests in Two Wheeler Drivers Travelling on Pune Banglore National Highway (NH4) India

Pulmonary function tests were studied in two wheeler drivers daily travelling on national highway 4(NH4). 50 drivers were included in study after applying exclusion criteria. Control group (50) of age matched healthy paramedical workers from KIMS, University was included. Approval from Institutional Ethical Committee was obtained. Informed written consent was taken from each participant. Spirometric lung function test were carried out in department of Physiology at KIMSU, Karad. Pulmonary function parameters included were FVC (Forced Vital Capacity), FEV1 (Forced Expiratory Volume in First second of FVC), FEV1% (FEV1 as % of FVC), PEFR (Peak Expiratory Flow Rate in liters/sec), FEF25-75% (Forced Expiratory Flow Rate during 25 to 75 % of expiration), FEF 0.2-1.2 (Forced Expiratory Flow between 0.2 -1.2 liters of expiration) and MVV (Maximum Voluntary Ventilation). After computing mean and SD of each parameter group comparison was done. Impairment of lung function (Mixed type i. e restrictive & obstructive) was found in the study group compared to control group. The impairment was more after long term exposure. Protective measures like use of face mask and periodical health check up was advised.

Effect of Triiodothyronine on Bronchial Asthma. III.

In two previous communications we demonstrated that triiodothyronine (T3) improved cases of chronic bronchial asthma (CBA). In this communication we administered T3 in a dose of 40 microgram/day for a period of sixty days to twelve cases of CBA aged less than 38 years who had had the condition for more than 5 years and were not on steroids or chromoglycate. All were outpatients. Respiratory functions including vital capacity and timed expiratory volume were tested before and after the period of drug administration. Patients were also advised to record the number of attacks and amount of bronchodilators used. All patients had their % T3 uptake and thyroxine (T4) serum level examined before the experiment. Ten normal persons of matching ages and sexes had their blood examined for % T3 uptake and levels as control. The results have shown that the patients had normal % T3 uptake and T4 levels in blood. Their vital capacity increased by an average of 4.27%, their first-second expiratory volume by 17.58% (P less than 0.0025), their second-second expiratory volume by 13.74% (P less than 0.0025%), and their maximal ventilatory volume by 12.95% (P less than 0.0025). Five cases had an increase of over 20% and 5 cases had practically no increase or a mild reduction. Subjective improvement and reduction in amount of bronchodilators used correlated well with the improvement in ventilation. It is argued that T3 acts through having the capacity to increase cAMP, a main messenger in bronchodilation that is known to be deficient in asthmatics.