Background Multiplayer Virtual Reality-Based Simulations (MPVR-based simulations) with immersive 3D environments have become an important tool in interprofessional education (IPE). However, instruments to measure interprofessional socialization in MPVR-based education are limited. The Interprofessional Socialization and Valuing Scale (ISVS) is a useful tool for evaluating interprofessional socialization. This pilot study aimed to adapt and validate the ISVS-24 for use in interprofessional MPVR-based simulations settings. Methods Seventy-two participants, including anesthesiology residents (at novice, junior, and senior levels), general physicians, and nurses, were recruited voluntarily. The ISVS-24 was cross-culturally adapted and reviewed by experts for content validity in the MPVR simulation context. Participants completed the adapted ISVS after undergoing an interprofessional MPVR-based simulation. Structural validity was assessed using factorial analysis through principal component analysis. Content validity was measured using the mean content validity index (CVI). Consistency validity was evaluated with Pearson correlation coefficients (PCC), and reliability was assessed using Cronbach’s alpha. Results The Kaiser-Meyer-Olkin test indicated sampling adequacy (0.885), and Bartlett’s sphericity test was significant (χ2(42) = 472.725, p < 0.05). A three-section structure was confirmed. The mean CVI was 0.815, with 21 valid items (Aiken’s V ≥ 0.5). Among the 72 respondents, 40 were female (55.6%) and 32 were male (44.4%); 26 were anesthesiology residents (36.1%), 23 were general physicians (31.9%), and 23 were nurses (31.9%). The overall Cronbach’s alpha was 0.959. PCC for all items exceeded the r table value (> 0.232) with p < 0.05, showing significant item relationships. Conclusions The adapted version of ISVS for MPVR simulation-based education has good validity and reliability to assess interprofessional socialization in an MPVR-based simulation setting.
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