Abstract. Introduction. The authors substantiated the relevance of the study of the consequences of the pandemic in a globalized economy, which always responds to unexpected challenges in the world community, despite the country's geographical and territorial location. Purpose. The main purpose of the research is to study the consequences of the pandemic for the economies of different countries of the world, reviewing the forecasts of experts and the post-crisis world economy. Results. The measures used and applied by different countries of the world to prevent the spread of the infectious disease COVID-19 were considered. The analytical estimation of the main macroeconomic indicators of the leading countries of the world during the pandemic is performed, among which are per capita expenses on the pandemic, the GDP growth rate in 2019-2020 and forecasts for 2021-2022, quarantine restrictions, introduced in the world countries, and Ukraine in particular, including the analysis of the economic condition of separate spheres of life and economic branches as a result of the introduction of rigid quarantine restrictions. The world practice of preventing the spread of the disease is considered, the basic approaches used to overcome COVID-19 are outlined. Conclusions. Real and projected data on the pace of development of the global post-pandemic economy are summarized. It has been proven that the effects of the pandemic have affected and will continue to exacerbate not only economic issues, they will manifest themselves in medical, social, psycho-emotional burden, which, in turn, requires the state to develop a comprehensive approach in addressing these issues.