As a cutting-edge technology in the field of communication, 5G technology poses new challenges and opportunities to the teaching of communication principles courses. "Communication Principles", as the core course of these majors, must be constantly updated to adapt to the development of new communication technologies. This article takes the "Principles of Communication" course as an example, combines the characteristics of 5G technology and education, discusses the characteristics of the course and the current teaching situation, and proposes a series of teaching reform measures. These measures include structural adjustments to theoretical course content, using Matlab virtual simulation technology to strengthen experimental teaching, combining postgraduate entrance examination professional knowledge explanations, introducing after-school 5G practical training and professional certificate assessment, etc. Practice has proven that these teaching reforms can effectively improve the integration of theory and practice, enhance students' ability to analyze and solve problems, and better meet the training needs of applied talents.