Experimental Model For Study Research Articles

An experimental and kinetic modeling study on pyrolysis of chlorobenzene

An experimental and kinetic modeling investigation of the pyrolysis of chlorobenzene (PHICL) was performed with a flow reactor using synchrotron vacuum ultraviolet photoionization mass spectrometry in the temperature range of 800–1507 K and pressures of 30 to 760 torr. Eighteen pyrolysis products were identified and quantified. A detailed kinetic model describing the PHICL pyrolysis process was developed and validated against the available experimental results. The sensitivity analysis of PHICL pyrolysis shows that the PHICL consumption is most sensitive to the unimolecular decomposition reaction R2PHICL=o-C6H4+Cl at 30 Torr. The H-abstraction reaction of PHICL+Cl=R2PHICL+HCl plays a dominant role in PHICL consumption at 760 Torr. The mole distribution analysis and rate of production (ROP) analysis shows that PHICL tends to be decomposed via unimolecular decomposition reactions to produce small molecules such as o-C6H4, C4H4, C4H2, and C2H2 at 30 Torr; while with pressure increasing, recombination reactions of chlorophenyl (RxPHICL (x = 2–4)) radicals forming C12H8Cl2, and ipso-addition reactions of chlorophenyl/phenyl to PHICL yielding C12H8Cl2/C12H9Cl are critical to the consumption of the precursor, further leading to the formation of tricyclic chlorinated aromatic C18H11Cl.

A comprehensive experimental and kinetic modeling study of di-isobutylene isomers: Part 2

A wide variety of high temperature experimental data obtained in this study complement the data on the oxidation of the two di-isobutylene isomers presented in Part I and offers a basis for an extensive validation of the kinetic model developed in this study. Due to the increasing importance of unimolecular decomposition reactions in high-temperature combustion, we have investigated the di-isobutylene isomers in high dilution utilizing a pyrolysis microflow reactor and detected radical intermediates and stable products using vacuum ultraviolet (VUV) synchrotron radiation and photoelectron photoion coincidence (PEPICO) spectroscopy. Additional speciation data at oxidative conditions were also recorded utilizing a plug flow reactor at atmospheric pressure in the temperature range 725–1150 K at equivalence ratios of 1.0 and 3.0 and at residence times of 0.35 s and 0.22 s, respectively. Combustion products were analyzed using gas chromatography (GC) and mass spectrometry (MS). Ignition delay time measurements for di-isobutylene were performed at pressures of 15 and 30 bar at equivalence ratios of 0.5, 1.0, and 2.0 diluted in ‘air’ in the temperature range 900–1400 K using a high-pressure shock-tube facility. New measurements of the laminar burning velocities of di-isobutylene/air flames are also presented. The experiments were performed using the heat flux method at atmospheric pressure and initial temperatures of 298–358 K. Moreover, data consistency was assessed with the help of analysis of the temperature and pressure dependencies of laminar burning velocity measurements, which was interpreted using an empirical power-law expression. Electronic structure calculations were performed to compute the energy barriers to the formation of many of the product species formed. The predictions of the present mechanism were found to be in adequate agreement with the wide variety of experimental measurements performed.

ZIF for CO2 Capture: Structure, Mechanism, Optimization, and Modeling

The requirement to counter carbon emissions is becoming urgent. Zeolitic Imidazolate Frameworks (ZIFs) have been extensively investigated recently for storing and separating gases, especially carbon dioxide. The present review aims to summarise the state of the art of ZIFs for carbon dioxide capture focusing on the structure, mechanism, optimisation, and modelling. The methods utilised for carbon capture are briefly summarized. The morphology of ZIFs with different topologies, N2-CO2 adsorption-desorption isotherms, X-ray diffraction patterns, thermo-gravimetric analysis (TGA) results are discussed to give insights into the textural properties, structure-activity relationship and structural-thermal stability of ZIFs. Finally, the experimental optimisation techniques, modelling and simulation studies for improving CO2 capture by ZIFs are discussed. This review should provide a comprehensive and quick understanding of this research area. It is timely to summarize and review ongoing developments in this growing field to accelerate the research in the right direction.

Experimental and numerical model studies of dike-break induced flood processes over a typical floodplain domain

Experimental and numerical model studies of dike-break induced flood processes over a typical floodplain domain

An experimental and kinetic modeling study on the low and intermediate temperatures oxidation of NH3/O2/Ar, NH3/H2/O2/Ar, NH3/CO/O2/Ar, and NH3/CH4/O2/Ar mixtures in a jet-stirred reactor

The oxidation of neat NH3 and co-oxidation of NH3 with H2/CO/CH4 are investigated both experimentally and numerically. Experiments were carried out in a fused silica jet-stirred reactor with a fixed residence time of 1.5 s. Oxidation products of NH3/O2/Ar, NH3/H2/O2/Ar, NH3/CO/O2/Ar, and NH3/CH4/O2/Ar mixtures were measured at various temperatures from 950 K to 1400 K, and equivalence ratios of 0.5∼2.0. A detailed kinetic model was developed and validated by the present experimental data and literature data. The experimental results indicate that NH3 reactivity is promoted by H2 addition below 950 K and by CO/CH4 addition below 1175 K. Kinetic analysis shows that HO2 radical is an important intermediate to trigger the oxidation of NH3. HO2 radicals can be converted into OH radicals through the catalytic cycle reactions of NO+HO2NO2+OH and NO2+HNO+OH, realizing the consumption of NH3. Then NH2 is oxidized by HO2 radicals and NO2 through the pathway of NH2→H2NO→HNO→NO→NO2 for producing more active radicals. H2 can provide a large amount of HO2 and H radicals, and CO relies on the interaction of NH2 and CO (NH2+COHNCO+H) to provide H radicals for achieving the catalytic cycle, while CH4 faces the competition between CH3 and H radicals for NO2 (CH3+NO2CH3O+NO and NO2+HNO+OH), resulting in the ability of H2 to lower the NH3 reactivity onset much stronger than that of CO and CH4. With the increase in temperature, the HO2 radicals tend to inhibit the oxidation of NH3 by the chain-termination reaction of NH2+HO2NH3+O2. The oxidation of NH3 is gradually dominated by the independent interaction of fuels and H/OH/O radicals. H/OH/O radicals promote the conversion of NHi (i = 0, 1, 2) to NO. As a result of the stronger ability to carry H atoms, the most active NO chemistry is found in the co-oxidation of NH3/CH4, while the least active NO chemistry is discovered in the oxidation of neat NH3 for the strong reduction effect of NHi. In stoichiometric conditions, the formation of NO mainly depends on NH radicals, and the formation and reduction of NO by N and NH2 radicals are almost equivalent. In lean conditions, as the importance of NH radicals decrease, the production of NO is mainly dependent on the conversion of NH2 to NO through HNO intermediate.

An experimental and chemical kinetic modeling study of the role of potassium in the moist oxidation of CO

The effect of KCl on moist CO oxidation in a laminar flow quartz reactor was investigated. Experiments were conducted in the absence of O2 (gasification), as well as under reducing and fuel-lean conditions, in the temperature range 873–1573 K, and the results were interpreted in terms of a chemical kinetic model. The impact of reactions on the quartz surface of the reactor was carefully examined. Under the conditions of interest, KCl reacts with SiO2 to form potassium silicates, releasing HCl to the gas phase. This reaction alters the condition of the quartz surface, making it more active in catalyzing radical recombination, even in the presence of water vapor. Under gasification and reducing conditions, loss of hydrogen atoms on the wall, enhanced by the exposure to KCl, strongly inhibits CO oxidation, with gas-phase inhibition playing a minor role. Under fuel-lean conditions, the state of the surface does not affect the CO oxidation and the observed inhibition can be attributed to gas-phase reactions. The most important reaction for the inhibition is the chain terminating step KO2 + OH ⇆ KOH + O2. Assuming that this reaction proceeds without a barrier, the rate constant is controlled by a long-range dipole–dipole interaction. We calculate a capture rate constant of 2.5E15 T−0.163 cm3 mol−1 s−1. This value, which is significantly higher than earlier estimates used in modeling, allows a satisfactory prediction of the inhibiting effect of KCl on CO oxidation under oxidizing conditions.

An experimental and kinetic modeling study on NH3/air, NH3/H2/air, NH3/CO/air, and NH3/CH4/air premixed laminar flames at elevated temperature

Ammonia combustion helps to realize the off-site use of renewable energy. To understand the combustion characteristics of NH3, laminar burning velocities (SL) of NH3/air, NH3/H2/air, NH3/CO/air, and NH3/CH4/air with various mole fractions of H2, CO, and CH4 in fuel (α), equivalence ratios (ϕ = 0.7∼1.4) at elevated initial temperature (Ti = 298∼423 K) were measured in a constant-volume combustion vessel. Based on updated chemistry of NH2, NNH, N2H2, and NOx, a detailed kinetic model with 169 species and 1268 elementary reactions was developed and validated against the SL, NOx emissions, NH3/NO interaction, and ignition delay times measured by this work and literature. The experimental results show that SL of NH3/H2/air, NH3/CO/air, and NH3/CH4/air flames have different dependence on α. It is nearly exponential for NH3/H2/air flame, non-linear for NH3/CO/air flame, and nearly linear for NH3/CH4/air flame. NH3/air flame has the strongest temperature dependence, followed by NH3/H2/air, NH3/CH4/air, and NH3/CO/air flames. The updated NH3 chemistry, especially NNH chemistry (NNH = N2 + H, N2H2 + H = NNH + H2, and N2H2 + O = NNH + OH), enables the present model obtain better temperature dependence of NH3/air flame. Kinetic modeling analysis shows that the production and reduction of NOx are preferred by the lean and stoichiometric flames of NH3/H2/air, NH3/CO/air, and NH3/CH4/air because of the increased concentrations of NHi and H/O/OH radicals. In the lean flames of NH3/H2/air, NH3/CO/air, and NH3/CH4/air, H2, CO, and CH4 can promote the conversion of NH2 to NO, and relatively inhibit the NO reduction by NH2, resulting in the increase in NO emissions. In the rich flames of NH3/H2/air and NH3/CO/air, NH2 and NH can produce N2H2 and N2H3 through reactions of NH2 + NH = N2H2 +H and NH2 + NH = N2H3, which dominate the promotion and inhibition of laminar flame propagation, respectively.

Experimental and constitutive model study on the mechanical properties of a structural plane of a rock mass under dynamic disturbance.

An accurate description of the mechanical properties and deformation characteristics of a structural plane of a rock mass with a large chamber or slope under the ultimate stress with periodic stress disturbances is of great significance to ensure the stability and safety of underground rock engineering. By theoretically analysing the strength effect of a structural plane of a rock mass under dynamic disturbance, a criterion for the occurrence of shear damage on a structural plane of a compressed rock mass under dynamic disturbance is proposed. The results of the cyclic disturbance kinetic test show that there is a disturbance threshold for the shear failure of the structural plane under different disturbance stresses. When the disturbance stress is lower than the disturbance threshold, the cumulative plastic strain stabilizes with an increasing number of cycles; when the disturbance stress is higher than the disturbance threshold, an S-shaped curve of cumulative plastic strain versus the number of cycles is observed, revealing the progressive damage process and mechanism of such a rock structure plane under periodic dynamic disturbance. Based on perturbation concept theory, the relationship between the accumulated plastic strain and the number of cyclic loadings is similar to the relationship between strain and time, the creep curve. A new nonlinear viscous element is proposed, and the nonlinear element and the deformation element considering structural plane closure and sliding are combined with the Burgers model to form an 8-element nonlinear viscoelastic‒plastic creep constitutive model. Using the global optimization algorithm of 1stOpt, model validation and parameter identification are performed on the experimental data, and the results show that the model curve has a very good agreement with the experimental data. The model can accurately reflect the deformation characteristics of a structural plane of a rock mass under periodic dynamic disturbance. These research results provide a new idea for analysing disturbance-induced geohazards.

Unraveling the differences of the reactivity of 3-methylthiophene and benzothiophene over bulk NiMoS catalysts using an experimental and kinetic modeling study

The reactivities of two model molecules, 3-methylthiophene (3MT) and benzothiophene (BT), representative of those contained in a FCC gasoline, was investigated over two Ni-promoted MoS2 (NiMoS) bulk catalysts prepared according to two synthesis procedures, a metathesis-like one (NiMoS-M) and an innovative one including an in-situ Ni promotion (NiMoS-NG). The second procedure led to smaller NiMoS particles with a narrower size distribution and higher Ni promotion rate. Differences in the activity of the catalysts were observed for the transformation of 3MT and BT. BT was more reactive than 3MT over NiMoS-M whereas the reactivity of both sulfur molecules became similar over NiMoS-NG. The kinetic modeling indicated a higher adsorption constant of 3MT over NiMoS-NG than NiMoS-M and similar adsorption constant of BT on both catalysts. The results have been interpreted taking into account the differences of the catalyst properties in relation with the mechanisms involved in the transformation of both molecules.

Exploring the chemistry behind low temperature auto-ignition of isopropyl nitrate in an RCM: An experimental and kinetic modeling study

The low-temperature auto-ignition chemistry of isopropyl nitrate (iPN) was experimentally and numerically investigated in the present study. The ignition delay times (IDTs) of iPN were measured stoichiometrically over a temperature range of 560–600 K at effective pressures of 5 and 10 bar in a rapid compression machine. A two-stage ignition phenomenon of iPN was observed. Both the first-stage IDTs and total IDTs vary rapidly within the narrow temperature range investigated (∼40 K). A recent iPN kinetic mechanism proposed by Fuller and Goldsmith for pyrolysis studies was extended. The reaction kinetics of CH3CHO + NO2 has been theoretically calculated at 500–1500 K and 0.01–100 atm. The rate information of CH3 + NO2 was updated based on previous theoretical results. The O2-addition channel of acetyl radical (CH3CO), which accounts for the first-stage IDT, was also considered in the present work. The extended iPN kinetic model predicts the two-stage IDTs well. Simulation results suggest that the IDTs are most sensitive to the following two reactions: (1) CH3 + NO2 = CH3O + NO; (2) CH3 + NO2 = CH3NO2. The former promotes the overall reactivity by yielding the reactive methoxy radical, while the latter forms a relatively stable product (i.e., CH3NO2). The reaction of CH3CHO + NO2 = CH3CO + HONO supplements the formation of CH3CO. The different consumption channels of CH3CO radicals (the O2-addition reaction and the decomposition reaction) lead to different chain reactions yielding OH radicals with increasing temperature in the ignition process. The “NONO2 loop” is the main route for OH formation in the studied conditions, which is mainly responsible for the iPN ignition.

The effect of variations in water level on wave overtopping discharge over a dike: An experimental model study

The water level during a storm event is never constant but variable in nature. A variable water level leads to varying crest freeboards at the coastal defense structure. A change in crest freeboards is directly linked to a changing average overtopping discharge q over the coastal defense structure. The existing prediction formulae for q are developed for constant water level ( C W L ) and do not take into account its variability ( V W L — variable water level) during a storm event. Hence, in this study the influence of the V W L on q was investigated experimentally. Model tests were conducted in the wave flume facility at Ghent University, where a range of V W L was modelled as representative for typical storm surges (total variation of the water level d h = 0.75–4.8 m) and a range of storm durations (time t = 2.7–22 h). During testing the q for these cases of V W L over a reference impermeable sloping (seaward slope of the structure cot( α ) = 2) dike structure was measured. Initial validation of model results for the C W L situation showed that the model setup was capable of reproducing the predicted q values from Eurotop (2018). For the V W L situation it was noted that the existing prediction formulae (Eurotop, 2018) are overestimating the measured q value, especially for smaller relative crest freeboards (relative freeboards R c / H m 0 < 1 . 5 ) when the smallest freeboard is considered. By using linear regression a new equivalent relative crest freeboard was derived to reduce the difference between q predicted by existing EurOtop (2018) and q measured during variable tests. The new equivalent freeboard is mainly dependant on the relative crest freeboard during the peak of the storm ( R c p e a k / H m 0 ), as well as the total storm surge variation ( d h). The existing formulation from EurOtop (2018) was kept by replacing R c by this new equivalent crest freeboard. The adapted formula for q is able to accurately predict the overtopping discharge for both, C W L and V W L situation. • 2D Physical model tests on wave overtopping performance of a smooth dike. • Influence of variable water level conditions on the average wave overtopping discharge. • New equivalent relative freeboard is determined to include this effect in the EurOtop formula for non-breaking waves. • Predictions are significantly improved with the new equivalent relative freeboard for the new data.

Relative infectivity of the SARS-CoV-2 Omicron variant in human alveolar cells.

With the continuous emergence of highly transmissible SARS-CoV-2 variants, the comparison of their infectivity has become a critical issue for public health. However, a direct assessment of the viral characteristic has been challenging because of the lack of appropriate experimental models and efficient methods. Here, we integrated human alveolar organoids and single-cell transcriptome sequencing to facilitate the evaluation. In a proof-of-concept study with four highly transmissible SARS-CoV-2 variants, including GR (B.1.1.119), Alpha (B.1.1.7), Delta (B.1.617.2), and Omicron (BA.1), a rapid evaluation of the relative infectivity was possible. Our system demonstrates that the Omicron variant is 5- to 7-fold more infectious to human alveolar cells than the other SARS-CoV-2 variants at the initial stage of infection. To our knowledge, for the first time, this study measures the relative infectivity of the Omicron variant under multiple virus co-infection and provides new experimental procedures that can be applied to monitor emerging viral variants.

Experimental Design, Equilibrium Modeling and Kinetic Studies on the Adsorption of Methylene Blue by Adsorbent: Activated Carbon from Durian Shell Waste.

For the first time, activated carbon from a durian shell (ACDS) activated by H2SO4 was successfully synthesized in the present study. The fabricated ACDS has a porous surface with a specific surface area of 348.0017 m2·g-1, average capillary volume of 0.153518 cm3·g-1, the average pore diameter of 4.3800 nm; ash level of 55.63%; humidity of 4.74%; density of 0.83 g·cm-3; an iodine index of 634 mg·g-1; and an isoelectric point of 6.03. Several factors affecting Methylene Blue (MB) adsorption capacity of ACDS activated carbon was investigated by the static adsorption method, revealing that the adsorption equilibrium was achieved after 90 min. The best adsorbent pH for MB is 7 and the mass/volume ratio is equal to 2.5 g·L-1. The MB adsorption process of ACDS activated carbon follows the Langmuir, Freundlich, Tempkin, and Elovich isotherm adsorption model, which has determined the maximum adsorption capacity for MB of ACDS as qmax = 57.47 mg·g-1. The MB adsorption process of ACDS follows the of pseudo-second-order adsorption kinetic equation. The Weber and Morris Internal Diffusion Model, the Hameed and Daud External Diffusion Model of liquids have been studied to see if the surface phase plays any role in the adsorption process. The results of thermodynamic calculation of the adsorption process show that the adsorption process is dominated by chemical adsorption and endothermic. The obtained results provide an insight for potential applications of ACDS in the treatment of water contaminated by dyes.

Facile Synthesis of Regenerative Framework Adsorbent for Organic Dyes: Experimental and Artificial Neural Modeling Studies

AbstractThe primary challenge in the design and synthesis of materials having higher affinity, rapid uptake, and superior adsorption capacity is to achieve the balance between performance and economy for real‐world application. The present study unfolded the synthesis of a regenerative framework adsorbent employing greener condition, that shows excellent performance with an ultrahigh adsorption capacity and 99 % removal efficiency for a range of water polluting contaminants, i. e., organic dyes of industrial importance. A pseudo‐second‐order kinetics model shows a favorable fit for the adsorption process. The maximum adsorption capacity calculated by the Langmuir isotherm was found to be highest among many reports in the minimum concentration range, which directly indicates its outstanding efficiency even at lower contaminant concentration. The framework has good reusability and remarkable adsorption performance after being used for several repeated cycles. Consequently, the adsorption behavior of real effluent sample is also investigated using the current system. Additionally, artificial intelligence based on artificial neural network modeling has been executed successfully to estimate and model process parameters of dye removal by adsorption technique which results in mutual correlation between lab‐based techniques and neural based modeling for solving environmental concerns.

Effect of oxygen injection sites on fraction of delivered oxygen (FDO2) during noninvasive ventilation – An experimental lung model study

Effect of oxygen injection sites on fraction of delivered oxygen (FDO2) during noninvasive ventilation – An experimental lung model study

Effect of oxygen injection sites on fraction of delivered oxygen (FDO2) during noninvasive ventilation – An experimental lung model study

Effect of oxygen injection sites on fraction of delivered oxygen (FDO2) during noninvasive ventilation – An experimental lung model study

A wide-range experimental and kinetic modeling study of the pyrolysis and oxidation of 1-butyne

Allyl and propargyl radicals are involved in the production of the first aromatic ring, which is considered a crucial process in forming polycyclic-aromatic hydrocarbons and soot. 1-Butyne decomposes to propargyl radicals during its pyrolysis and oxidation. To improve our knowledge of the kinetics of 1-butyne, its pyrolysis, oxidation, and laminar flame speed properties have been measured. Pyrolysis experiments were performed in a single-pulse shock tube at 2 bar in the temperature range 1000 – 1600 K. Ignition delay times for 1-butyne/‘air’ mixtures were measured at pressures of 1, 10, 30, and 50 bar, in the temperature range 680 – 1580 K, at equivalence ratios of 0.5, 1.0, and 2.0 using rapid compression machines and shock tubes. Furthermore, laminar flame speeds were measured at ambient temperature, at p = 1, 2, 3 atm, over an equivalence ratio range of 0.6 – 1.9. A new detailed mechanism for 1-butyne has been developed and widely validated using the new experimental data and those available in the literature. Important reactions of 1-butyne pyrolysis and oxidation are determined through flux and sensitivity analyses.

On the laminar flame propagation of C5H10O2 esters up to 10 atm: A comparative experimental and kinetic modeling study

Biodiesel is a family of renewable engine fuels with carbon-neutral nature. In this work, three C5H10O2 esters (methyl butanoate, methyl isobutanoate and ethyl propanoate), which can serve as model compounds of biodiesel and represent linear and branched methyl esters and linear ethyl esters, were investigated to characterize their laminar flame propagation characteristics up to 10 atm and unravel the effects of isomeric fuel structures. A high-pressure constant-volume cylindrical combustion vessel was used to achieve laminar burning velocity measurements at 1–10 atm, 423 K and equivalence ratios of 0.7–1.5, while comparative experimental work was performed on a heat flux burner at 1 atm, 393 K and equivalence ratios of 0.7–1.6 for methyl butanoate and ethyl propanoate. The laminar burning velocity generally decreases with increasing pressure and increases in the order of methyl isobutanoate, methyl butanoate and ethyl propanoate, which shows distinct fuel isomeric effects. A kinetic model of C5H10O2 esters was developed and validated against the new data in this work and previous data in literature. Modeling analyses were performed to provide insight into the fuel-specific flame chemistry of the three esters isomers. Remarkable differences in radical pools of three ester isomers are concluded to be responsible for the observed fuel isomeric effects on laminar flame propagation. The feature of two ethyl groups connected to the ester group in ethyl propanoate facilitates the ethyl production and inhibits the methyl and allyl production, making it propagate fastest among the three isomers. The branched structure feature of methyl isobutanoate with methyl and i-propyl groups connected to the ester group prevents the ethyl formation and results in considerable CH3 and allyl production, which decelerates its laminar flame propagation.

Biosorption of zinc (II) from synthetic wastewater by using Inula Viscosa leaves as a low-cost biosorbent: Experimental and molecular modeling studies

The use of biosorption as a strategy for lowering the amount of pollution caused by heavy metals is particularly encouraging. In this investigation, a low-cost and efficient biosorbent, Inula Viscosa leaves were used to remove zinc ions (Zn2+) from synthetic wastewater. A Fourier transform infrared spectroscopy experiment, a scanning electron microscopy experiment, and an energy dispersive X-ray spectroscopy experiment were used to describe the support. Several different physicochemical factors, such as the beginning pH value, contact duration, initial zinc concentration, biosorbent dose, and temperature, were investigated in this study. When the Langmuir, Freundlich, Temkin, Toth, and Redlich-Peterson models were used to match the data from the Inula Viscosa leaves biosorption isotherms, it was found that the biosorption isotherms correspond most closely with the Langmuir isotherm. On the other hand, the kinetic biosorption process was investigated using pseudo-first-order, pseudo-second-order (PS2), and Elovich models. The PS2 model was the one that provided the most accurate description of the biosorption kinetics. The thermodynamics process shows the spontaneous and endothermic character of Zn2+ sorption on Inula Viscosa leaves, which also entails the participation of physical interactions. In addition, the atom-in-molecule analysis, density functional theory, and the conductor like screening model for real solvents, were used to investigate the relationship that exists between quantum calculations and experimental outcomes.

Mechanical Ventilation in ARDS With an Automatic Resuscitator.

The Oxylator is an automatic resuscitator, powered only by an oxygen cylinder with no electricity required, that could be used in acute respiratory failure in situations in which standard mechanical ventilation is not available or feasible. We aimed to assess the feasibility and safety of mechanical ventilation by using this automatic resuscitator in an animal model of ARDS. A randomized experimental study in a porcine ARDS model with 12 pigs randomized to the Oxylator group or the control group (6 per group) and ventilated for 4 h. In the Oxylator group, peak pressure was set at 20 cm H2O and PEEP was set at the lowest observed breathing frequency during a decremental PEEP titration. The control pigs were ventilated with a conventional ventilator by using protective settings and PEEP at the crossing point of collapse and overdistention, as indicated by electrical impedance tomography. Our end points were feasibility and safety as well as respiratory mechanics, gas exchange, and hemodynamics. After lung injury, the mean ± SD respiratory system compliance and PaO2 /FIO2 were 13 ± 2 mL/cm H2O and 61 ± 17 mm Hg, respectively. The mean ± SD total PEEP was 10 ± 2 cm H2O and 13 ± 2 cm H2O in the control and Oxylator groups, respectively (P = .046). The mean plateau pressure was kept to < 30 cm H2O in both groups. In the Oxylator group, the tidal volume was transiently > 8 mL/kg but was 6 ± 0.4 mL/kg at 4 h, whereas the breathing frequency increased from 38 ± 4 to 48 ± 3 breaths/min (P < .001). There was no difference in driving pressure, compliance, PaO2 /FIO2 , and pulmonary shunt between the groups. The mean ± SD PaCO2 was higher in the Oxylator group after 4 h, 74 ± 9 mm Hg versus 58 ± 6 mm Hg (P < .001). There were no differences in hemodynamics between the groups, including blood pressure and cardiac output. Short-term mechanical ventilation by using an automatic resuscitator and a fixed pressure setting in an ARDS animal model was feasible and safe.