Experimental Feeding Period Research Articles

Effect of feeding egg yolk and cholesterol on serum cholesterol levels.

THE ROLE OF exogenous cholesterol as a factor in the development of arteriosclerosis has received much attention and attempts to raise serum cholesterol levels in human beings have been made. 1 In general, it appears difficult to alter substantially serum cholesterol levels in normal human beings by feeding cholesterol or cholesterol-containing substances. Evidence concerning the reasons for this difficulty is accumulating. Endogenous sources of cholesterol appear to be of great importance. 2 One report suggested that cholesterol fed in the diet tends to depress synthesis in the body. 3 Although the number of patients studied by us is small and the relation of plasma cholesterol levels to the development of arterial disease in man is not clear, it was thought worth while to report the results of the present study for two reasons: first, because of the duration of the experimental feeding periods and, second, because the results show clearly

305. The excretion of borate by the dairy cow

1. Two Ayrshire cows in mid-lactation were fed for over 40 days on production rations containing from 16 to 20 g. of added borax.2. The daily excretion of borate during the experimental feeding period was 13–16 g. in the urine, 5–7 g. in the faeces, and 0·3–0·6 g. in the milk, compared with figures of 1·5, 1·0 and 0·1 g. for the control period. There was no detectable retention of borate in the body, and the levels of borate excretion rapidly returned to normal after cessation of the experimental feeding.3. No adverse effects were observed as a result of the borate feeding. The live weights of the animals remained normal, and there was no diuretic effect. The milk yield was also well maintained. The borate content of the milk increased from the normal level of 0·7 to over 3·0 p.p.m.4. Attention is drawn to the risk of using farmyard manure which has been made from the excreta of animals fed on boronated rations.