Abstract The objective of this study was to evaluate the sensitivity of flash floods to future climate change in the Amman–Zarqa Basin, Jordan. Historical daily rainfall and temperature data from 1970 to 2018 were collected, along with projected daily data derived from general circulation models (GCMs) forecast spanning 2019–2060. The methodology involved analyzing historical and model forecast data, conducting trend analysis, mapping changes in land use, estimating runoff volume, selecting indicators, assigning their weights through the analytical hierarchy process, and generating vulnerability maps. Analysis of precipitation trends revealed a 14.61% decrease in total annual rainfall over the past 48 years; however, future projections indicate a 5.26% increase. Downstream sub-catchments in the arid portion are projected to receive higher rainfall, while upstream sub-catchments are expected to experience a substantial decline, resulting in an overall reduction in runoff. Moreover, our findings demonstrate a rising trend in mean temperature, which is expected to persist. Remote sensing data indicate a 14.76% expansion of urban areas, indicative of rapid population growth. Although no highly vulnerable sub-catchments were identified, downstream sub-catchments 8 and 9 exhibited moderate vulnerability to flash floods, which can be attributed to the increase in rainfall and insufficient stormwater infrastructure.