Maritime glaciers in the southeastern Tibetan Plateau (SETP) are particularly sensitive to changes in climate, and their changes directly and severely affect regional water security and glacier-related hazards. Given their large societal importance, a better understanding of the mass balance of maritime glaciers in the SETP, a key variable for characterizing the state of glacier health, is of great scientific interest. In this review, we synthesize in situ, satellite-based observations and simulations that present an overall accelerating negative mass balance of maritime glaciers in the SETP in recent decades. We hereby highlight a significant spatiotemporal difference in the mass balance of maritime glaciers across the SETP and investigate the drivers of the accelerated mass loss of these glaciers in recent years. We find that accelerated glacier mass loss agrees with the variabilities in temperatures rising and precipitation decreasing at regional scales, as well as the spatial patterns of widespread melt hotspots (e.g., thin debris, ice cliffs, supraglacial ponds, and surface streams), the expansion of glacial lakes, enlarged ice crevasses, and frequent ice avalanches. Finally, the challenges of the mass balance study of maritime glaciers and future perspectives are proposed. Our review confirms the urgent need to improve the existing glacier inventory and establish comprehensive monitoring networks in data-scarce glacierized catchments, and it suggests paying particular attention to the development of glacier mass-balance models that coupe multiple physical processes at different interfaces to predict the status of maritime glaciers and their responses to climate change. This study can inform the sustainable management of water resources and the assessment of socio-economic vulnerability due to glacier-related hazards in the SETP and its surroundings in the context of marked atmospheric warming.