Introduction Facial infiltrating lipomatosis (FIL) is a rare congenital and benign condition, resulting from mature nonencapsulated adipocytes penetrating into neighbouring structures. Individuals with FIL present with unilateral facial and craniofacial hemihypertrophy, alongside various medical and dental complications of the affected side. Case report At birth, the infant had an evident right sided facial swelling which remained asymptomatic but continued to increase in size. Magnetic resonance imaging confirmed right-sided lipomatous hyperplasia and genetic testing confirmed a somatic mutation to PIK3CA; the cause of cell hyperproliferation, often identified in FIL cases. On the right side, the child has developed epidermal naevus and mild hearing and visual impairment. A multidisciplinary team (paediatric medicine and dentistry, dermatology, ENT and plastics at Great Ormond Street Hospital) has contributed to managing the complex condition. At 12 months old, paediatric dentistry observed premature eruption of teeth 53, 54 and 84 and hyperplasia of the upper right alveolar arch. At 5 years-old, the child presented with premature exfoliation of primary teeth and premature eruption of permanent teeth 14, 16, 41, 42 and 46 with bilateral crossbites. Management A dental prevention regime has been implemented and the child remains caries free. The developing dentition will continue to be monitored with consideration of orthodontic management. Presently, as the child remains stable, a conservative approach without surgical or medical intervention has been adopted. His vision is corrected with glasses. Conclusion FIL is associated with dental developmental anomalies and medical complications of the affected side, requiring multidisciplinary care.
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