Introduction: Pelvic floor muscle exercises represent voluntary contractions and relaxations of the levator ani muscles. This muscle group gives support to the vagina, bladder, and urethra. Urethral profilometry is a study that assesses the closing function of the urethral sphincter. There is limited scientific evidence regarding the changes in pressure values of the Maximum Urethral Closing Pressure (MUCP) during a voluntary contraction of the pelvic floor muscles (C-MUCP). Objective: During a urodynamic test, evaluate the change in MUCP at rest and during voluntary contraction after verbal command, in patients from two tertiary referral hospitals. Material and methods: Retrospective and cross-sectional study of two tertiary referral hospitals in Mexico. This study focused on reviewing hospital records of adult patients who underwent a urodynamic study from January 2016 to February 2022. Obstetric clinical history data and MUCP results at rest and in C-MUCP during urodynamics were taken. IBM SPSS Statistics version 22 statistical program was used. Results: 928 patients with a mean age of 58 years were evaluated. Eighty three percent were postmenopausal women. An inverse relationship was observed between age and MUCP both at rest (p=<0.001) and in C-MUCP (p=0.009). Neurogenic disease and postmenopausal status had no significant relationship with the ability to increase MUCP. Sixty five percent of the population achieved a clinically significant increase of the MUCP. Conclusion: There is a direct negative relationship between age, resting MUCP and C-MUCP. In patients with both neurogenic and non-neurogenic pathology, the rate of clinically significant increase in MUCP was low.