Excessive Force Research Articles

Government justification of police actions against protesters: biopolitics in Poland during the Covid-19 pandemic

ABSTRACT How did the government justify aggressive, and, at times, violent police actions against demonstrators during the pandemic? We use a biopolitical framework to empirically explore how leading members of Poland’s government justified protest policing. During the Covid-19 pandemic, Poland’s PiS-led government, like others across Europe, implemented social distancing measures that curtailed the right to peaceful assembly. The government justified aggressive crowd control tactics such as kettling to ‘protect’ society from what they perceived as illegal and unruly protestors who seek to cause indirect mass harm, e.g. spread the virus via street protesting, or cause direct harm to police officers through physical acts of protester aggression. The government argued that protesters, instead of being whom the state must keep safe from biological harm, actually threaten a vulnerable police force and other institutions. The government projected their own vulnerability to cast protesters as biological threats to the nation and, thus, as dangerously norm-breaking ‘others,’ in order to justify surveillance of demonstrators and aggressive police tactics.

Analisis Postur Kerja Pada Bagian Packing Menggunakan Metode ManTRA Dan REBA

PT. Indonesia Plafon Semesta is a company engaged in manufacturing, this company produces various kinds of PVC ceilings. Problems faced by PT. Indonesia Plafon Semesta is the activity of making PVC ceilings in the packing section, where the activity conditions or workers' posture is not good. When packing by squatting and bending, the position is less ergonomic, resulting in excessive force exertion and the risk of injury. This research aims to determine the level of complaints felt by workers in body parts by identifying them using the Nordic Body Map (NBM), Manual Task Risk Assessment (ManTRA) to determine the level of risk experienced by workers and knowing how many angles are formed. Rapid Entire Body Assessment (REBA) is used to calculate worker posture and provide a score of the worker's proposed posture using Anthropometry. Data processing was carried out using NBM calculations for workers who had the highest score of 51 and the lowest 44. Knowing the level of risk experienced by workers with Mantra protection with the back, forearms, neck and wrists > 15 and the angle formed in the REBA calculation using score 10. Improvement of the proposed posture with Anthropomerti with a TPO calculation of 32.5 cm and JTD cm of 69 by paying attention to the object being worked on with REBA calculation results having a score of 7.

Race, Political Ideology, and Support for Defunding the Police in the United States

ABSTRACT This study investigates public attitudes toward “Defund the Police” proposals amid U.S. protests against racism and police brutality. Analysis of 2021 General Social Survey data reveals that racial identity and political ideology significantly shape these attitudes. Black Americans demonstrate the highest support for defunding, followed by Hispanic Americans and other racial and ethnic minorities, reflecting diverse historical and cultural experiences with the government. Political ideology further polarizes opinions, with liberals more supportive and conservatives more opposed. These findings highlight the complexities of addressing systemic issues in criminal justice and the importance of social identities in shaping attitudes toward police reform.

‘We Don’t Have Any Honor Because We Are khwaja sira’: Police Violence and Discrimination Against the Khwaja Sira Community in Swat, Pakistan

Abstract This qualitative study examines police violence and discriminatory policing practices targeting the third gender community, known in Pakistan as khwaja sira. Employing a phenomenological analysis, we conducted a qualitative study involving in-depth interviews with 45 khwaja sira in Mingora, Khyber Pakhtunkhwa, Pakistan, recruited through purposive and snowball sampling. Using Interpretative Phenomenological Analysis of the interview transcripts: two distinct themes emerged regarding the lived experiences of khwaja sira in Swat, Pakistan: experiencing multiple forms of violence by police; and managing abuses of policing power. Findings shed light on the challenges khwaja sira face regarding police violence and misconduct, including neglect from law enforcement officers to register their cases, biased practices within police precincts, and discrimination associated with their engagement in sex work or their gender nonconformity. Findings underscore the need for comprehensive interventions aimed at addressing police violence experienced by the khwaja sira community.

Development of an Algorithm for Determining the Class of an Obstacle in the Process of its Interaction with the Manipulator

The article discusses the problem of determining the nature of an obstacle using a force sensor for terrain mapping. Three classes of objects have been introduced: the first class is "static" obstacles, the second class is "moving" obstacles, the third class is "unstable" obstacles. To conduct experiments, a simulation system was built in the Gazebo modeling environment, including a manipulator with the ability to horizontally move a probe with a force sensor and a set of obstacles corresponding to three classes of obstacles. All experiments were carried out using the ROS framework, the Gazebo simulator and the Movelt manipulation software. Processing of signals from the force sensor showed that the sig­nals for the three classes of obstacles are different, which makes it possible to identify the class based on sensor readings. Based on the analysis of data received from the sensor, rules were formed that make it possible to determine the class of an obstacle during its interaction with the manipulator in real time. To determine the obstacle class, the values of the force sensor signals are considered, smoothed by the moving average method. According to the rules discussed in the article, an algorithm was developed to determine the class of obstacle, which was implemented in the Gazebo modeling environment. Testing of the algorithm showed the stability of its operation under the given experimental conditions. Successful determination of the obstacle class will allow one not only to construct a map of the area, but also to prevent damage to the device when exposed to a "static" object with excessive force. The presented approach can be expanded to narrower classes of obstacles that characterize objects that can be encountered by a mobile device when mapping a forest area.

Income level as a differentiating factor in assessing the impact of migration on economic growth

Aim. To study the nature of the impact of migration on economic growth depending on the level of gross domestic product (GDP) per capita and the direction of migration flows.Objectives. Study of theoretical approaches to the research of the impact of labor migration on economic growth; analysis of factors that differentiate the assessment of the impact of migration flows on economic growth indicators; collection and analysis of statistical information for the development of econometric models for assessing the impact of migration on economic growth.Methods. The authors used general scientific methods of research, such as deduction, analysis, synthesis. Statistical methods of data analysis were applied, linear regression models were built.Results. The research shows that the impact of migration on economic growth in countries with different levels of GDP per capita is due to different factors. For developed economies, the positive factors of the impact of immigration on economic growth are replenishment of scarce labor resources; improvement of labor force quality due to structural changes caused by the transition of the permanent working-age population to new professional fields. For countries with a low level of GDP per capita we can identify a number of positive factors of the impact of emigration (with a negative balance of migration growth) on economic growth. In particular, the outflow of excess labor force creates conditions for reducing unemployment; remittances of migrants support effective demand in the consumer market, contribute to the development of the banking system and investment in the country of origin; the expansion of social ties leads to the development of human capital, increasing the potential for innovation.Conclusions. The value of correlation coefficients in the constructed regression models indicates that there is a weak correlation between the variable characterizing the volume and nature of migration in the country (the ratio of migration balance to population) and the variable characterizing economic growth (GDP per capita at purchasing power parity) only for the group of high-income countries. There is little statistical dependence of these variables for other groups of countries. With regard to econometric modeling of the impact of migration on economic growth, this means that it is necessary to develop separate models for each group of countries depending on the level of GDP per capita and the direction of migration flows.

Devourers of the Afro-American Light: Histories of “Place” via the Imposition of White Rage and Police Brutality in Detroit

Devourers of the Afro-American Light: Histories of “Place” via the Imposition of White Rage and Police Brutality in Detroit

Surgical Management for Boutonniere Disease

Boutonniere disease is a hand injury causing extension lag or restriction in the proximal interphalangeal joint and hyperextension in the distal interphalangeal joint. This condition often arises from direct laceration or closure damage to the central tendon, rheumatoid arthritis, osteoarthritis, Dupuytren contracture, pulley injury, burns, and other conditions. Surgical management for Boutonniere deformity relies on the expertise of the attending physician and involves both non-surgical and surgical options. In acute cases, conservative therapy should be pursued, while in chronic cases, conservative management may be advised. Surgical intervention is used to transform excessive extension force of the distal interphalangeal joint into extension force of the proximal interphalangeal joint. This is necessary to heal an open rupture of the central tendon. Surgical techniques for chronic deformity are complex due to variables and hand surgeons' expertise. There is no definitive surgical therapy for persistent buttonhole deformity, but several approaches have been documented in case studies. These include terminal tenotomy, collateral band surgery, central tendon surgery, tendon transfer and grafting, stepwise extension mechanism readjustment surgery, and arthrodesis. Central tendon surgery addresses the central tendon, where injured tissue transforms into scar tissue, resulting in delayed extension of the proximal interphalangeal joint. Tendon transfer or grafting have been documented for rotator cuff mechanism rehabilitation, but no definitive guidance exists for these techniques. Curtis treatment introduced a sequential therapy approach for traumatic buttonhole deformity, which involves splinting, excising the transverse reticular ligament, resecting and lengthening the collateral ligament, and repositioning the core tendon. Arthrodesis may be applicable in cases of advanced arthritis, coronal plane deformity, functional impairment, or elderly patients. There are no definitive indications for surgical interventions for persistent buttonhole deformity, and outcomes may be variable or inferior. Understanding the deformity, its progression, and patient's functional constraints is crucial for effective treatment

The journey to building a diverse, equitable, and inclusive American Medical Informatics Association.

The American Medical Informatics Association (AMIA) Task Force on Diversity, Equity, and Inclusion (DEI) was established to address systemic racism and health disparities in biomedical and health informatics, aligning with AMIA's mission to transform healthcare. AMIA's DEI initiatives were spurred by member voices responding to police brutality and COVID-19's impact on Black/African American communities. The Task Force, consisting of 20 members across 3 groups aligned with AMIA's 2020-2025 Strategic Plan, met biweekly to develop DEI recommendations with the help of 16 additional volunteers. These recommendations were reviewed, prioritized, and presented to the AMIA Board of Directors for approval. In 9 months, the Task Force (1) created a logic model to support workforce diversity and raise AMIA's DEI awareness, (2) conducted an environmental scan of other associations' DEI activities, (3) developed a DEI framework for AMIA meetings, (4) gathered member feedback, (5) cultivated DEI educational resources, (6) created a Board nominations and diversity session, (7) reviewed the Board's Strategic Planning for DEI alignment, (8) led a program to increase diversity at the 2020 AMIA Virtual Annual Symposium, and (9) standardized socially-assigned race and ethnicity data collection. The Task Force proposed actionable recommendations that focused on AMIA's role in addressing systemic racism and health equity, helping the organization understand its member diversity. This work supported marginalized groups, broadened the research agenda, and positioned AMIA as a DEI leader while reinforcing the need for ongoing transformation within informatics.

Why DON'T We "Say Her Name"? An Intersectional Model of the Invisibility of Police Violence Against Black Women and Girls.

Racialized police violence is a profound form of systemic oppression affecting Black Americans, yet the narratives surrounding police brutality have disproportionately centered on Black men and boys, overshadowing the victimization of Black women and girls. In 2014, the #SayHerName campaign emerged to bring attention to the often-overlooked instances of police brutality against Black women and girls, including incidents of both nonsexual and sexual violence. Despite these efforts, mainstream discourse and psychological scholarship on police violence continue to marginalize the experiences of Black women and girls. This raises a critical question: Why DON'T we "Say Her Name"? This article employs intersectional frameworks to demonstrate how the historic and systemic factors that render Black women and girls particularly vulnerable to police violence also deny their legitimacy as victims, perpetuate their invisibility, and increase their susceptibility to state-sanctioned violence. We extend models of intersectional invisibility by arguing that ideologies related to age, in addition to racial and gender identities, contribute to their marginalization. Finally, we reflect on how psychological researchers can play a pivotal role in dismantling the invisibility of Black women and girls through scientific efforts and advocacy.

Longitudinal tooth fracture indicating a questionable prognosis for an endodontist

Introduction and Objectives: Longitudinal fracture or vertical fracture of a tooth occurs at any level in the root and extends vertically. It has a high incidence of occurrence in the first molars. The most frequent sites to occur are the buccolingual surface and proximal surfaces of teeth. The etiology of fracture involves different factors in endodontically treated and non-endodontically treated teeth. Longitudinal fractures become the most challenging to diagnose and treat. This paper reviews these aspects of challenges and discusses the advantages and limitations of dental materials used for the treatment. Review Methods: PubMed and Google Scholar databases were searched for articles on longitudinal tooth fractures between 2007 and 2022. The 16 current articles were selected. Brief Description of the State of Knowledge: As per the review of the literature, longitudinal fracture of the tooth is the most common fracture to occur due to excessive forces on the root canal-treated tooth. This occurs in endodontically treated teeth due to long-term application of calcium hydroxide, cracks caused during root canal preparation extended by the pressure of root canal obturation, and in non-endodontically treated teeth due to cyclic and heavy masticatory stress, and habitual chewing of hard food especially in males. Summary: Functional and esthetic outcomes following longitudinal fracture treatment are important considerations in the case of anterior teeth. Longitudinal fracture or vertical fracture of a tooth occurs mostly in the first molars. It is crucial to identify and manage actors for good prognosis, as restoration at a time can reduce fracture extension prevent microleakage.

Living less safely through the pandemic in England for people with serious mental and physical health conditions: qualitative interviews with service users and carers of Black African, Caribbean, and South-Asian descent.

COVID-19 Ethnic Inequalities in Mental health and Multimorbidities (COVEIMM) is a mixed methods study to explore whether COVID-19 exacerbated ethnic health inequalities in adults with serious mental and physical health conditions. We analysed data from electronic health records for England and conducted interviews in Birmingham and Solihull, Manchester, and South London. Sites were selected because they were pilot sites for the Patient and Carer Race Equality Framework being introduced by NHS England to tackle race inequalities in mental health. Prior to the pandemic people in England with severe mental illnesses (SMIs) faced an 11-17-year reduction in life expectancy, mostly due to preventable, long-term, physical health conditions. During the pandemic there was a marked increase in deaths of those living with an SMI. This qualitative interview study aimed to understand the reasons underlying ethnic inequalities in mortality and service use during the COVID-19 pandemic for adult service users and carers of Black African, Black Caribbean, Indian, Pakistani, and Bangladeshi backgrounds living with serious multiple long-term mental and physical health conditions. We took a participatory action research approach and qualitative interviews undertaken by experts-by-experience and university researchers Participants were purposively sampled by ethnicity, diagnoses, and comorbidities across three geographically distinct sites in England. Transcriptions were coded inductively and deductively and analysed thematically. Findings indicated multiple points along primary and secondary health pathways for mental and physical health that have the potential to exacerbate the unjust gap in mortality that exists for Black and Asian people with SMIs. Issues such as timely access to care (face-to-face and remote), being treated in a culturally appropriate manner with empathy, dignity and respect, and being able to use services without experiencing undue force, racism or other forms of intersectional discrimination were important themes arising from interviews. These poor experiences create systemic and enduring healthcare harms for racialised groups with SMIs that need to be addressed. Our findings suggest a need to address these, not only in mental health providers, but across the whole health and care system and a need to ensure more equitable healthcare partnerships with service users, carers, and communities from racialised backgrounds who are often excluded.

Characteristics of adult male victims in intimate heterosexual relationships from domestic violence police narratives

Background settingDomestic violence (DV) perpetrated against male victims has received little attention in the literature, since men are generally the perpetrators rather than victims of DV. This study examines the characteristics of adult male victims and female Persons of Interest (POIs) suspected and/or charged with perpetrating a DV offence in an intimate relationship.MethodsWe analyzed the results from a text mining study on half a million (492,393) police-attended DV events from 2005 to 2016 in New South Wales (Australia). 7.3% (13,896) events involving an adult male victim and a female POI in an intimate relationship were included.ResultsOver three-quarters (77.5%; 10,775) of DV events had at least one abuse type recorded, with the most common being “unspecified assault” (57.3%), followed by verbal abuse (34.1%), and punching (29.1%). Half of events (51.2%; 7,128) had an injury recorded by the police, with “cut/abrasion(s)” the most common (41.6%), followed by “red mark/sign” (25.4%), and “bruising” (15.8%). A total of 2,196 (15.8%) DV events had a mention of a mental illness for the POIs and 570 (4.1%) for the victims. Mood disorders had the most mentions for both POIs (37.0%) and victims (32.8%). Among victims, anxiety related disorders saw the largest increase (14.0%) in mentions from 2005 to 2016, followed by depression (8.0%).ConclusionOur findings represent population level data insights from DV events involving an adult male victim in an intimate relationship with a female POI. Our findings align with existing studies suggesting that female POIs are more likely than male POIs to use objects/weapons, employ verbal abuse, and perform minor acts of physical violence. Female POIs had 4 times the number of mental illness mentions than male victims indicating that mental illness could be a risk factor for DV, while the increase in anxiety disorders and depression for male victims corresponds with research that associates mental illnesses and DV victimhood. This study highlights the need for a greater awareness and support for male victims of DV.

Impact of applied and preceding pressure on performance and reversible swelling of lithium-ion pouch cells with varying microporous separators

During the compression of battery cells in battery pack production, high forces occur temporarily due to the viscoelastic behavior of the cell components. The magnitude of these forces depends on the compression speed. Shortening the production time and, thus, increasing the compression speed is desirable for cost reduction. However, it must be ensured that the cells are not negatively affected by increased forces during production. The impact of these preceding forces, acting on the cell before operation, and the applied force during operation on the performance and the reversible swelling of 5Ah NMC811/graphite lithium-ion pouch cells are investigated in this study. To this end, a universal compression testing machine was adapted to enable high-precision thickness measurements under defined constant pressure and temperature conditions. In addition, the effects of different microporous separators manufactured via dry process and wet process in an otherwise identical cell configuration were investigated. In the test procedure, the pressure was incrementally increased from 0.01MPa to 2.5MPa. Each measurement was performed at the distinct constant pressure levels, followed by a subsequent measurement at a reference pressure of 0.2MPa to evaluate the impact of the preceding step. The results revealed that elevated preceding pressures on the cell can reduce the discharge rate capability on higher C-rates by up to 11%. The discharge rate capability of the cells with the wet-processed separator was more significantly influenced by increasing applied and preceding pressure than for those with the dry-processed separator. It was found that the reversible swelling of the cell was reduced by applying higher pressures, whereas elevated preceding pressure increased the reversible swelling. The results of this study suggest that cells should not be subjected to excessive forces before operation, for instance, during battery pack production, as this can negatively affect performance and swelling behavior. Furthermore, the mechanical stability of the separator during the pack production process should also be considered when designing a cell.

Trends and topics: Characterizing echo chambers’ topological stability and in-group attitudes

Nowadays, online debates focusing on a wide spectrum of topics are often characterized by clashes of polarized communities, each fiercely supporting a specific stance. Such debates are sometimes fueled by the presence of echo chambers, insulated systems whose users’ opinions are exacerbated due to the effect of repetition and by the active exclusion of opposite views. This paper offers a framework to explore how echo chambers evolve through time, considering their users’ interaction patterns and the content/attitude they convey while addressing specific controversial issues. The framework is then tested on three Reddit case studies focused on sociopolitical issues (gun control, American politics, and minority discrimination) during the first two years and a half of Donald Trump’s presidency and on an X/Twitter dataset involving BLM discussion tied to the EURO 2020 football championship. Analytical results unveil that polarized users will likely keep their affiliation to echo chambers in time. Moreover, we observed that the attitudes conveyed by Reddit users who joined risky epistemic enclaves are characterized by a slight inclination toward a more negative or neutral attitude when discussing particularly sensitive issues (e.g., fascism, school shootings, or police violence) while X/Twitter ones often tend to express more positive feelings w.r.t. those involved into less polarized communities.

A-343 Novel In-Line Hemolysis Detection on a Blood Gas Analyzer for Capillary Samples

Abstract Background Point-of-care (POC) blood gas and electrolyte analyzers utilizing whole blood as the predominant sample type are blinded by the presence of hemolysis until today. Moreover, capillary samples are particularly vulnerable to in-vitro hemolysis due to excessive force applied during sample collection. Here, we introduce the GEM Premier 7000 with iQM3 (GEM 7000) which incorporates automatic, in-line hemolysis detection in capillary blood gas samples without a need for additional sample volume or reagents. Methods The hemolysis detection module which is integrated into the disposable GEM cartridge uses acoustophoretic technology and photometric measurements to detect hemolysis in whole blood. In GEM 7000, hemolysis of ≥ 116 mg/dL was found to have significant interference with potassium results. A hemolysis flag is presented as the degree of hemolysis: none (0 - 50 and 51 - 115), mild (116 - 200 and 201 - 300), moderate (301 - 400), and gross (≥401). Due to volume limitations with native capillary samples and challenges in assessing hemolysis levels with a comparator assay, venous blood spiked volumetrically with hemolysate and transferred to capillary devices was used to verify the hemolysis flag performance. An agreement analysis was performed using the Roche cobas hemolysis value. The device's (GEM 7000) ability to flag hemolyzed capillary samples is demonstrated in a simulated clinical setting using native and contrived fingerstick capillary samples. Results Hemolysis verification with transferred capillary samples demonstrated that 98.2% (274/279) of samples were correctly flagged based on the cobas hemolysis value of spiked hemoglobin. Hemolysis in the native capillary samples (N = 235) was primarily distributed in the 0-50 mg/dL range. Additionally, native capillary samples altered using vigorous flea mixing (> 1 minute) showed hemolysis distribution over a wide hemolysis degree (none to gross), and their potassium results were flagged accordingly. Conclusions By providing integrated hemolysis detection in capillary blood sample measurements, the GEM Premier 7000 with iQM3 system can provide quality and confidence in the clinical interpretation of critical results such as potassium.

Construction and validation of a nomogram model for predicting different sites of ankle pain in runners with chronic ankle instability

This study aimed to establish a risk prediction nomogram model for anterolateral, mediolateral, and posterolateral ankle pain in runners with chronic ankle instability (CAI) and analyse the potential risk factors for pain at different ankle sites. Thirty recreational runners with CAI who reported ankle pain in the anterolateral, mediolateral, or posterolateral regions were recruited for this study. Kinematic, kinetic, and electromyographic data during running were collected using motion capture system, 3-D force platform, and surface electromyography system. These data were used to generate a dynamic nomogram. The results showed that anterolateral ankle pain in runners with CAI may be caused by insufficient gastrocnemius muscle strength (OR 0.85, 95% CI 0.73–0.97), excessive ground reaction force (GRF, OR 2.64, 95% CI 1.25–6.22), and an increased percentage of ankle energy absorption (OR 9.11, 95% CI 1.50–77.79). Mediolateral ankle pain might be contributed by greater ankle inversion angle (OR 1.08, 95% CI 1.01–1.00) and GRF (OR 2.13, 95% CI 1.17–4.31). Moreover, posterolateral ankle pain was predicted by increased ankle adduction angle (OR 1.06, 95% CI 1.00–1.12), increased GRF (OR 2.16, 95% CI 1.07–4.80), and decreased dynamic stability (OR 0.20, 95% CI 0.05–0.68). To prevent ankle pain, runners with CAI should be encouraged to focus on improving the neuroreceptor sensitivity of the gastrocnemius muscles, and retraining their energy absorption patterns.

Police violence reduces trust in the police among Black residents

Police violence reduces trust in the police among Black residents

Text Mining and Unsupervised Learning Techniques for Tweet Classification in the Peruvian Social Context

Background: Currently, there has been an exponential growth in the volume of unstructured data, especially with the use of social networks. Technological progress has allowed the adoption of processes, techniques, and methods to obtain information from these data. Objective: This work aims to analyze and classify Tweets in the context of Peru's social upheaval, using text mining (TM) and unsupervised learning (UL) techniques. Methods: More than 268k tweets were collected and processed, with the hashtag of the trends occurred in the first two weeks of February 2023: #ParoNacional, #RenunciaYa and #Renuncia. Within a radius of 1000km from the city of Lima. Data cleaning and feature selection techniques were used. Then, UL techniques, such as clustering and sentiment analysis, were applied to classify the Tweets generated in social networks using the Loss Distribution Approach (LDA) model. Results: The result of the analysis of Tweets related to the social upheaval in Peru shows a polarization in the opinions of users, with one group supporting the protests and another criticizing them. Recurring themes have been identified as the resignation of the president, Lima centralism, congressional shutdown, corruption, and social inequality. The sentiment analysis shows a mix of positive and negative emotions, with words grouping negative sentiment being the most recurrent. Sentiment was classified into three polarity categories: positive, negative, and neutral, corresponding to 37%, 58% and 5%, respectively. There is also criticism of the government for its lack of action and police violence during demonstrations. Conclusions: Finally, it is concluded that UL techniques have been effective in classifying Tweets according to their polarity.

Dual role of Sfrp4 in bone remodelling during orthodontic tooth movement.

The objective of this study was to determine changes in gene expression by establishing an orthodontic tooth movement (OTM) rat model with appropriate and excessive orthodontic force. Using a closed coil nickel-titanium spring, the OTM was carried out to apply a mesial force of 50 or 100 g to the maxillary first molars. Micro-CT, histological and immunohistochemical staining were used to evaluate the bone formation at the tension site and the bone resorption and bone formation at pressure site. Then RNA sequencing and bioinformatic analysis were performed. According to the results of the Mirco-CT scan of OTM rat models, both the 50 g group and the 100 g group showed variable degrees of reduction in alveolar bone density on the tension and pressure sides. The results of histological and immunohistochemical staining demonstrated that the periodontal tissue and osteogenic ability of the 50 g group were restored at the 14 days, while the 100 g group caused severe periodontal tissue damage. The GO and KEGG analysis results, as well as the number of differentially expressed genes (DEGs), varied depending on the loading time and value of appliance, according to the results of the RNA sequencing. And the immunohistochemical staining results showed that Sfrp4 functioned by efficiently influencing both bone formation and bone absorption. Appropriate orthodontic force value could cause appropriate movement of teeth in rats without adverse periodontal damage. Simultaneously, distinct gene expression patterns were observed at various force levels and time intervals.