Excellent Strategy Research Articles

Auto-Deposited Microparticle Composite Coating for Low-Cost and Efficient Daytime Radiative Cooling.

Radiative cooling is an excellent strategy for mitigating global warming, by enhancing heat fluxes away from the Earth, thus balancing the Earth's heat flow. However, for randomly particle-dispersed radiative cooling materials, the particle content as high as 94-96 wt % or 60 vol %, far exceeds the critical pigment percentage (40-50%) of traditional coatings, preventing its large-scale application. Here, inspired by particle deposition under gravity in solution, we demonstrate an auto-deposited SiO2 composite radiative cooling coating (ADRC) which reduces the amounts of particles required and lowers costs. This particle density gradient structure enhances the local volume fraction of particles, thereby the coating exhibits high solar reflectance (93%) and infrared emissivity (89%), contributing to a daytime subambient temperature drop of 12 °C. The cooling energy-saving potential of buildings in China utilizing the ADRC as roofs ranges from 6.42 to 13.52%. This low-cost and scalable radiative cooler is expected to reduce energy consumption and carbon emissions, addressing global warming issues.

Cerium oxide nanoparticles decorated on graphene oxide nanosheets as battery-type cathode material for supercapacitors.

Designing advanced materials that effectively mitigate the poor cycle life of battery-type electrodes with high specific capacities is crucial for next-generation energy storage systems. Herein, graphene oxide-ceria (GO-CeO2) nanocomposite synthesized via a facile wet chemical route is explored as cathode for high-performance supercapacitors. The morphological analysis suggests fine ceria (CeO2) nanoparticles dispersed over ultrathin graphene oxide (GO) sheets while structural studies reveal face-centered cubic phase of CeO2 in the nanocomposite. In-depth electrochemical performance investigation of the nanocomposite in 6M KOH aqueous electrolyte demonstrated its excellent battery-type behavior with least ion diffusion resistance and a superior cycle life resulting from the synergistic effect of redox-active CeO2 and 2D GO with abundant oxygen functionalities. Specifically, GO-CeO2 composite electrode delivered a maximum specific capacitance of 625.9F/g (52.2mAh/g) at 3 A/g current density, which is substantially higher than the capacitance values obtained for GO and CeO2 electrodes, and demonstrated an excellent cycling stability with∼100% capacitance retention after 10,000 CV cycles. Furthermore, a novel aqueous asymmetric supercapacitor (ASC) is explored with GO-CeO2 as positive and iron(III) oxyhydroxide (FeOOH) as negative electrode material in 6M KOH electrolyte which has also displayed good energy-power density combination along with excellent cycle stability. The study thus endorses rational design of nanocomposite materials with suitable functionalities as an excellent strategy in augmenting the performance of futuristic energy storage devices.

Research on the Effectiveness of Online Teaching Chinese as a Foreign Language

In recent years, there has been a new method of teaching Chinese as a foreign language: online teaching. Its distinct teaching style has a natural benefit when teaching Chinese as a foreign language, allowing the culture to proliferate in the information environment. However, how to increase the efficacy of online Chinese as a foreign language is one of the most significant topics to be explored right now. Paying attention to the success of online education is an excellent strategy to improve the quality of instruction. This research examines the elements that influence the success of online Chinese instruction and makes some tangible recommendations.

Early Surgical Resection in Pediatric Patients with Localized Ileo-Cecal Crohn's Disease: Results of a Retrospective Multicenter Study.

Background: Crohn's disease (CD) is an inflammatory bowel disease (IBD) that also affects pediatric patients. It frequently presents as a localized disease, affecting the ileocecal area, ileum, or colon. It requires targeted therapy to achieve a good quality of life and long-term control of disease activity. Despite multiple medical therapies available, several patients benefit from surgical treatment. The aim of our study is to demonstrate how an early surgical approach can bring an improvement in disease activity, evaluating the Simple Endoscopic Score for Crohn's Disease (SES-CD) and the Pediatric Crohn's Disease Activity Index (PCDAI). Methods: A retrospective multicenter study was carried out from 2008 to 2023, including 29 patients, affected by localized CD. These data were analyzed: demographics, SES-CD, and PCDAI, before and after surgery. The differences between groups were analyzed using Student's t-test for continuous variables, and Pearson's Chi-squared test or Fisher's exact test for categorical variables. Results: The SES-CD significantly decreased from 12 (median, range 1-15) to 0 (median, range 0-6) (p < 0.0001) and the PCDAI decreased from 30 (median, range 10-50) to 0 (median, range 0-15) (p < 0.0001). The rate of patients receiving enteral nutrition decreased from 51.7% preoperatively to 0% postoperatively (p = 0.0001). The rate of antibiotic use decreased from 13.8% to 0% (p = 0.0001). The rate of patients receiving ≥2 drugs decreased from 10.3% to 0% (p = 0.0001). Conclusions: The early surgical approach can be considered an excellent therapeutic strategy in patients with localized CD. Both parameters examined, SES-CD and PCDAI, demonstrated a clear improvement in the endoscopic images and in disease activity.

Implementasi Strategi Layanan Prima Pada MAN 2 Kota Serang Sebagai Madrasah Model Berbasis Boarding School

Madrasas as Islamic educational institutions have several advantages compared to other types of schools. The advantages possessed by madrasas include: vitality, fighting power, endurance, adaptability and evolution, and diversity. This research uses a quantitative approach by creating and distributing questionnaires. Primary data was obtained directly from the results of distributing questionnaires to respondents consisting of 100 student representatives, 38 educational staff representatives and 72 teaching staff representatives. Because the data from this research was obtained through distribution of armatures using the Google Form application, the data processing process also uses statistical formula applications that are integrated with existing questionnaires and Google Forms. The research aims to understand the forms of MAN 2 Serang City's excellent service strategy as a madrasa model or as a Boarding School-based madrasa as well as certain factors that support and inhibit the implementation of the excellent service strategy. The results of the research show that Madrasah Aliyah Negeri 2 Serang City acts as a model madrasa based on Islamic boarding schools and is a center for the development of madrasas in the surrounding area. Implementation of quality education services at Madrasah Aliyah Negeri 2 Serang City focuses on providing learning needs, one-stop integrated services (PTSP), digital-based services, as well as facilities and infrastructure services.

Aerobic exercise and metformin attenuate the cognitive impairment in an experimental model of type 2 diabetes mellitus: focus on neuroinflammation and adult hippocampal neurogenesis.

Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder that increases the prevalence of cognitive impairment in the geriatric population. Aerobic exercise is an excellent non-pharmacological therapeutic strategy to prevent Alzheimer's disease, the most common form of dementia. The exact molecular mechanism of aerobic exercise (Exe) as an intervention to counter cognitive decline is far from clear. Metformin is a first-line agent against T2DM with neuroprotective properties. The present study assessed the role of treadmill exercise in combination with a low dose of metformin (Met; 70mg/kg) in cognitive impairment and its associated molecular mechanism in T2DM rats. The experimental model of T2DM-associated cognitive decline was created by administration of a high-fat diet (HFD) with a low dose of streptozotocin (STZ; 35mg/kg). Neurobehavioral assessments were performed to evaluate spatial recognition and fear-conditioned memory across the groups: control, HFD + STZ, HFD + STZ + Exe, and HFD + STZ + Exe + Met. In addition, we performed immunohistochemistry and western blotting on the rat hippocampal tissue from the above groups for protein expression studies. T2DM rats showed a significant cognitive decline compared to the control group, which improved in the long-term exercise and metformin co-administered animals. The level of neuroinflammation was significantly elevated in the hippocampal tissue of T2DM rats compared to the control and lowered after exercise and metformin treatment. T2DM reduced mature neurons and neurogenesis while increasing astrogliosis and microgliosis, ameliorated by exercise and metformin treatment. Moreover, T2DM impaired hippocampal neurogenesis by reducing the canonical Wnt/β-catenin pathway, which got upregulated in exercise and metformin-co-administered rats. Long-term aerobic exercise with metformin treatment ameliorated neuroinflammation and promoted adult hippocampal neurogenesis via upregulating the canonical Wnt/β-catenin pathway in T2DM rats.

Unlocking Consumer Preferences: Sensory Descriptors Driving Greek Yogurt Acceptance and Innovation.

Greek yogurt, a traditional food with roots in Ancient Greece, Mesopotamia, and Central Asia, has become a dietary staple worldwide due to its creamy texture, distinct flavor, and rich nutritional profile. The contemporary emphasis on health and wellness has elevated Greek yogurt as a functional food, recognized for its high protein content and bioavailable probiotics that support overall health. This study investigates the sensory attributes evaluated by a panel of 22 trained assessors and the consumer preferences driving the acceptance of Greek yogurt formulations. Samples with higher consumer acceptance were characterized by sensory attributes such as "high texture in the mouth, surface uniformity, creaminess, apparent homogeneity, mouth-filling, grip in the mouth, ease of pick-up with a spoon, milk cream flavor, sweetness, and dairy flavor" (Tukey's test, p < 0.05). These attributes strongly correlated with consumer preferences, underscoring their importance in product optimization. The findings provide a framework for refining Greek yogurt formulations to address diverse market demands, achieving a balance between sensory excellence and practical formulation strategies. This research reinforces the significance of Greek yogurt as a culturally adaptable, health-promoting dietary component and a promising market segment for ongoing innovation.

Green Synthesis of ZnO Nanoparticles Using Delonix elata &amp; Gynura cusimbua Leaf Extracts and Evaluating Their In-vitro Antibacterial Properties

With an increasing focus on the application of nanoparticles in the field of research, this study aims to evaluate the in-vitro antibacterial properties of chemically and green synthesized zinc oxide nanoparticles (ZnO NPs) from two plant sources Delonix elata and Gynura cusimbua. The bioactive compounds present in the leaf extracts were utilized to stabilize the nanoparticles. UV-Visible spectrophotometry (UV-Vis), X-ray diffraction (XRD), and Scanning electron microscopy (SEM) were used to elucidate the optical and structural properties of the synthesized ZnO NPs. The in-vitro antibacterial potential of ZnO NPs were evaluated by Agar Disc Diffusion Assay against two pathogenic bacterial strains: Bacillus cereus, a gram-positive animal pathogen and Pseudomonas syringae, a gram-negative plant pathogen, making it a well-rounded approach. The UV–visible spectrum was measured in 250 – 400 nm range and the crystallite structure was analyzed via XRD. SEM-EDS (Energy-Dispersive X-ray Spectroscopy) analysis confirmed the nanostructures with partial nanoflakes and aggregates for all three samples of the synthesized ZnO NPs. The D. elata ZnO NPs showed relatively greater antimicrobial activity against both the bacterial strains than that of G. cusimbua ZnO NPs. Consequently, plant-based NPs may be an excellent strategy for developing versatile and environmentally friendly biomedical products. They have an added advantage due to their pre-existing medicinal properties, which make them a more suitable alternative to the broadly used chemically synthesized nanoparticles. KEY WORDS: Delonix elata, Gynura cusimbua, Zinc oxide Nanoparticle, antimicrobial activity, Bacillus cereus, Pseudomonas syringae.

Multicomponent Modular Synthesis of Thioacetals by Using Dichloromethane as the C1 Synthon under Mild Conditions

Thioacetals are an important category of sulfur‐containing compounds and versatile building blocks. Therefore, there is growing demand for the development of practical and modular methods to access various thioacetals from inexpensive and readily available commodity chemicals. Herein, we describe a novel one‐pot multicomponent protocol for thioacetals synthesis, especially benzylthio thioacetals synthesis, by employing feedstock chemical dichloromethane (DCM) as the C1 source under metal‐free, mild and simple conditions. Furthermore, its synthetic utility is further demonstrated by the preparation of deuterated thioacetals, large‐scale synthesis and broad functional group compatibility. Preliminary mechanistic studies indicate the dual roles of DBU as both a proton scavenger and a nucleophilic catalyst. This work provides not only an excellent complementary strategy to the established thioacetals synthesis, but also a new platform for DCM application.

Prediction of telecommunications market behavior based on LSTM models

The telecommunications services market faces essential challenges in an increasingly flexible and customer-adaptable environment. Research has highlighted that the monopolization of the spectrum by one operator reduces competition and negatively impacts users and the general dynamics of the sector. This article aims to present a proposal to predict the number of users, the level of traffic, and the operators’ income in the telecommunications market using artificial intelligence. Deep Learning (DL) is implemented through a Long-Short Term Memory (LSTM) as a prediction technique. The database used corresponds to the users, revenues, and traffic of 15 network operators obtained from the Communications Regulation Commission of the Republic of Colombia. The ability of LSTMs to handle temporal sequences, long-term dependencies, adaptability to changes, and complex data management makes them an excellent strategy for predicting and forecasting the telecom market. Various works involve LSTM and telecommunications. However, many questions remain in prediction. Various strategies can be proposed, and continued research should focus on providing cognitive engines to address further challenges. MATLAB is used for the design and subsequent implementation. The low Root Mean Squared Error (RMSE) values and the acceptable levels of Mean Absolute Percentage Error (MAPE), especially in an environment characterized by high variability in the number of users, support the conclusion that the implemented model exhibits excellent performance in terms of precision in the prediction process in both open-loop and closed-loop.

Adhesion Strategy for Cross-Linking AgNWs/MXene Janus Membrane: Stretchable and Self-Healing Electromagnetic Shielding and Infrared Stealth Capabilities.

Developing lightweight polymer shielding membranes with additional physicochemical properties is of great significance for addressing the complex contemporary security demands. However, precise structural design at the molecular level remains a challenge. Herein, a unique Janus composite membrane is assembled from conductive AgNWs/MXene 1D/2D network and polyurethane elastomer (MPHEA), displaying combined superior electromagnetic shielding effectiveness (EMSE) of up to 80dB and remarkable infrared stealth capability at a wide temperature range of room temperature to 50°C. Moreover, the endowed chemical crosslinking in the membrane resulted in the exceptional mechanical strength, self-healing, and superior adhesion. The maintained electromagnetic shielding (over 20dB) even under a strain of 40% and the recovered shielding efficiency of 90% after mechanical damage and self-healing are observed, which is attributed to the synergistic 3D polymer elastic and 1D/2D conductive network in the multi-dimensional crosslinked MPHEA@AgNWs/MXene composite membrane. This work has represented an excellent micro-nano structure design strategy on multifunctional electromagnetic wave manager in complex application scenario.

Lean healthcare: a science mapping of current progress and future research avenues.

This study intends to reveal the existing research stream and predict future research avenues for lean healthcare (LH). This paper analyzes the progress of LH research and identifies key trends, research gaps and future directions. By mapping the knowledge structure, the study offers insights into the effects of LH on healthcare efficiency, patient care and organizational performance. The review used the bibliometric approach, involving 319 journal articles retrieved from the Web of Science database. Two science mapping approaches (i.e. bibliographic coupling and co-word analysis) were performed to investigate the current knowledge structure and future research direction in LH. The current research trend in LH focuses on developing frameworks and strategic implementation by considering critical determinants and decision-making strategies. In the future, the research on LH will emphasize the holistic frameworks and efficient strategies for healthcare excellence, along with strategies to overcome barriers to its implementation. This study will benefit researchers and practitioners by advancing their understanding and applying LH principles. This study provides valuable practical implications for healthcare managers to navigate the complexities of lean implementation, optimize processes and drive sustainable improvements in the healthcare context.

Innovation as a Key Success for Competitive Excellence Strategy in SMEs of Iraq

Innovation as a Key Success for Competitive Excellence Strategy in SMEs of Iraq

The Impact of Service Quality, Facilities, and Location on Customer Satisfaction at PT Satya Trinadi Komira Perkasa in Tangerang Branch

This research examines the influence of service excellence, resource availability, and locational strategy on customer satisfaction at PT Satya Trinadi Komira Perkasa, with a primary focus on its Tangerang Regency branch. A descriptive approach was implemented, utilizing questionnaires as the primary tool for data gathering. The study involved 97 participants, selected using incidental sampling methods. Data analysis was performed through multiple linear regression, facilitated by SPSS 26 software. The results from partial testing indicate that service excellence and resource availability significantly enhance customer satisfaction, while locational strategy also holds considerable impact. Simultaneously, the findings from combined tests demonstrate that service excellence, resource availability, and locational strategy collectively have a profound effect on customer satisfaction, confirming Ha and rejecting Ho. The research emphasizes the pivotal role of service excellence in meeting and exceeding consumer expectations, fostering loyalty, and building a competitive edge. Adequate facilities and a strategically selected location complement service delivery, contributing to an improved customer experience. Businesses aiming to maintain market relevance must prioritize these factors. The study highlights the critical importance of aligning customer satisfaction strategies with operational efficiencies to secure sustainable growth.

The Impact of Service Quality, Facilities, and Location on Customer Satisfaction

This research examines the influence of service excellence, resource availability, and locational strategy on customer satisfaction at PT Satya Trinadi Komira Perkasa, with a primary focus on its Tangerang Regency branch. A descriptive approach was implemented, utilizing questionnaires as the primary tool for data gathering. The study involved 97 participants, selected using incidental sampling methods. Data analysis was performed through multiple linear regression, facilitated by SPSS 26 software. The results from partial testing indicate that service excellence and resource availability significantly enhance customer satisfaction, while locational strategy also holds considerable impact. Simultaneously, the findings from combined tests demonstrate that service excellence, resource availability, and locational strategy collectively have a profound effect on customer satisfaction, confirming Ha and rejecting Ho. The research emphasizes the pivotal role of service excellence in meeting and exceeding consumer expectations, fostering loyalty, and building a competitive edge. Adequate facilities and a strategically selected location complement service delivery, contributing to an improved customer experience. Businesses aiming to maintain market relevance must prioritize these factors. The study highlights the critical importance of aligning customer satisfaction strategies with operational efficiencies to secure sustainable growth.

Patent Review of Novel Biologics Targeting Opioid Use Disorder (2018-2024).

Drug overdose deaths in 2023 in the United States exceeded 107,000, with 80,000 of these deaths attributed to opioids alone. The emergence of synthetic opioids such as fentanyl and its analogues have worsened the opioid overdose epidemic. A novel approach to treat opioid overdose and opioid use disorder (OUD) has been the introduction of biologics, which include monoclonal antibodies that bind to circulating opioids, preventing them from reaching the central nervous system, or peptides that have antinociceptive effects but lack the abuse liability of synthetic opioids. A challenge in the treatment of opioid overdose has been renarcotization, where an overdose patient revived with naloxone can re-enter an overdose state from residual opioid in the body. Biologics such as vaccines and monoclonal antibodies are excellent strategies that have been demonstrated to prevent renarcotization. In this review, we retrieved and discussed patents filed in the past six (6) years that focus on novel biologics reported as treatments for opioid overdose and OUD. We also provide a perspective on the use of biologics as therapeutics for OUD and opioid overdose.

Screening the Dynamic Behavior of the Electrode-Electrolyte Interphase on Hard Carbon Via Scanning (Electrochemical) Probe Microscopy

Hard carbon is an attractive anode material for alkali-ion batteries, particularly for sodium-ion batteries (SIBs), due to the high storage capacity and the fact that HC can be produced from renewable bio-resources1. Similar to lithium-ion batteries (LIBs), the performance and operational stability of SIBs is dependent on the electrode electrolyte interface (SEI)2. Although, the SEI on graphite anodes (LIBs) and HC anodes (SIBs) have similar chemical properties, it has been shown that the SEI of SIBs is less stable and its stability is strongly dependent on the experimental conditions3. For example, we have recently investigated the SEI formation on spray-coated HC composite anodes in half-cell configurations in dependence of the electrolyte (ester and ether based including studies in the presence or absence of fluoroethylene carbonate (FEC) as an additive). Using scanning (electrochemical) probe microscopy (SEPM), such as scanning electrochemical microscopy (SECM), atomic force microscopy (AFM) and hybrid AFM-SECM, we could characterize the electrochemical and nanomechanical properties of the SEI4 -6.In this contribution, we present SEPM such as scanning electrochemical cell microscopy (SECCM)7, which has been used as attractive SPM technique for battery research8,9. SECCM is used to locally form SEI layers under different experimental conditions at the surface of HC composite anodes. The advantage of this approach is that on the same electrode surface e.g., different number of charge and discharge cycles can be performed forming localized SEI spots. These spots are then investigated by AFM and AFM-SECM to study the electrochemical and nanomechanical properties as well as dynamic behaviour such as the dissolution or possible swelling. Advantages and challenges of this in situ characterization of the formed interphases at post-Li battery electrodes are discussed. Acknowledgement This work contributes to the research performed at CELEST (Center for Electrochemical Energy Storage Ulm - Karlsruhe) and was funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany's Excellence Strategy – EXC 2154 – Project number 390874152 (POLiS Cluster of Excellence).

Qualitative and Quantitative Proton Content Analysis of Chemically Delithiated Ni-Rich NCM Materials

The development of long-lasting, high-energy-density batteries is crucial for the electrification of multiple sectors. The current scope for cathode active materials (CAM) to meet this demand are the next-generation Ni-rich layered oxides Li(NixCoyMnz)O2 (x+y+z=1, x>0.8). However, understanding their aging and degradation mechanisms is essential for improving their long-term stability. Chemical delithiation can be used to obtain pure CAM powders (rather than electrodes) at various degrees of delithiation to better understand these mechanisms and to develop countermeasures to improve cycling stability.[1] However, during chemical delithiation, protons can intercalate into the structure of CAMs by ion exchange of Li+ with H+.[2,3] This potentially compromises the use of chemically delithiated CAM powders for mechanistic studies.Therefore, we investigated the amount of protons in the chemically delithiated materials and devised approaches to minimize the proton content. Quantifying the proton content presents unique challenges, for which we employed prompt gamma activation analysis (PGAA) for precise quantification. Based on this benchmark technique, we developed a more accessible method to quantify the proton content by correlating the gas release during heat treatment of the chemically delithiated materials to their weight loss. Furthermore, we analyzed the bulk and surface properties of a Ni-rich chemically delithiated NCM as well as its thermal decomposition in order to gain insights into the effects of chemical delithiation and its comparability to electrochemical delithiation. While the bulk remained intact and followed the expected lattice development upon delithiation,[4] chemically delithiated materials exhibited higher overpotentials during galvanostatic cycling, indicating a surface reconstruction which in electrochemical delithiation only occurs after a large number of charge/discharge cycles. Therefore, while chemical delithiation is a powerful tool to access characteristics not possible with electrochemical delithiation, it must be employed with the utmost care and consideration. Acknowledgment This work was financially supported by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany's Excellence Strategy (EXC 2089/1 –390776260, e-conversion). The authors would like to thank BASF SE for providing the active materials used for this study. S Q. further acknowledges funding by the German Federal Ministry of Education and Research (BMBF) within the project Aqua-Pop (grant number 03XP0329B). References C. Tian, Y. Xu, D. Nordlund, F. Lin, J. Liu, Z. Sun, Y. Liu, and M. Doeff, Joule, 2, 464–477 (2018)S. Venkatraman and A. Manthiram, J Solid State Chem, 177, 4244–4250 (2004)J. Choi, E. Alvarez, T. A. Arunkumar, and A. Manthiram, ESL, 9, A241 (2006)F. Friedrich, B. Strehle, A. T. S. Freiberg, K. Kleiner, S. J. Day, C. Erk, M. Piana, and H. A. Gasteiger, J Electrochem Soc, 166, A3760–A3774 (2019)

Feedstock chemical dichloromethane as the C1 source for the chemoselective multicomponent synthesis of valuable 1,4,2-dioxazoles

The development of mild and practical strategies to produce value-added fine chemicals directly from inexpensive and readily available commodity chemicals is actively pursued by chemists. However, the application of feedstock chemical dichloromethane (DCM) as the C1 source in organic synthesis is still in its infancy. Herein, we describe a multicomponent strategy for the chemoselective synthesis of valuable 1,4,2-dioxazoles by using DCM as a C1 source. Critical to the success of this process is tuning of the type of nucleophiles to inhibit the easily-occurring side reactions. This approach features mild and simple conditions, excellent chemoselectivity, metal free, and broad substrate scope covering different types of nucleophiles. Furthermore, its synthetic utility is further demonstrated by the preparation of deuterated 1,4,2-dioxazoles, the late-stage functionalization of complex molecules and large-scale synthesis. Preliminary mechanistic studies indicate the dual roles of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) as both a proton scavenger and a nucleophilic catalyst. This work provides not only a platform for DCM application, but also an excellent complementary strategy to the established 1,4,2-dioxazoles synthesis.

Predicting the prognosis of Wilms tumor by peripheral blood cells: a real-world study of more than 30 years

BackgroundDespite established excellent treatment strategies for Wilms tumor (WT), effective prognostic evaluation methods were lacking. This study aims to examine prognostic factors for WT through real-world peripheral blood cell profiling.MethodsBasic data and pre-treatment laboratory indices from WT and non-WT children underwent Wilcoxon test analysis. Chi-square tests assessed the correlation between blood cells and the overall survival (OS) and event-free survival (EFS) of WT. Further the Log-rank test and multivariate Cox were used to identify independent prognostic factors for OS. Traditional accepted factors were included in multi-Cox and the nomogram was constructed to further validate the outcome.ResultsBlood cells significantly differed between WT and non-WT groups (P < 0.05). Univariate analysis revealed that NLR above 1.380, stage IV, M below 0.325 × 103/μL were linked with lower OS, and PLR below 94.632, LB above 3.570 × 103/μL, stage IV, M above 0.325 × 103/μL,age ≤ 3 years were meaningful for higher EFS (P < 0.05). While in the multifactorial COX, only M (HR:0.220, HR95%CI: 0.080 ~ 0.620, P = 0.004 and HR: 0.437, HR95%CI: 0.202 ~ 0.947, P = 0.036, respectively) and stage IV (HR: 7.890, HR95%CI: 1.650 ~ 37.770, P = 0.010 and HR: 3.720, HR95%CI: 1.330 ~ 10.408, P = 0.012, respectively) were independent prognostic factors for OS and EFS. These two variables also were significant after including recognized risk factors, and were demonstrated the predictability via nomogram.ConclusionsOS and EFS were poorer in WT children with M below 0.325 × 103/μL, suggesting the potential as a prognostic predictor for WT.