The recent halt in the production of CF 3 Br because of its deleterious effect on stratospheric ozone levels has intensified the search for new suppressants with comparable properties. In contrast to most proposed alternatives, earlier investigations of CF 3 I have reported excellent extinction efficiencies, sometimes superior to CF 3 Br on a molar basis. These findings have spurred an interest in elucidating more clearly the chemical effects produced by iodine-containing suppressants. In the present study, OH· and soot concentrations have been measured using fluorescence imaging and laser-induced incandescence methods, respectively, in a co-flowing, axisymmetric, atmospheric-pressure propane/air diffusion flame inhibited by CF 3 Br and CF 3 I. In addition, broadband molecular fluorescence (attributed to polycyclic aromatic hydrocarbons) has been monitored, and peak temperatures have been measured using two-line OH· laser-induced fluorescence. Overall, the two suppressants behave similarly when added to both the air and fuel streams, with the most notable exception being the greater enhancement of soot production for CF 3 Br addition at subextinction concentrations. CF 3 I is found to be slightly superior to CF 3 Br under our experimental conditions in terms of (I) requiring smaller mole fraction concentrations at extinction and (2) producing less within-flame soot. The reductions in the OH· concentrations with agent additions are essentially the same for CF 3 I and CF 3 Br.