ABSTRACT Computer aided design / computer aided manufacturing (CAD/CAM) systems are among the most technological advanced techniques in oral rehab today. Compared with conventional techniques, they can optimize the resistance and the adaptation of dental ceramics. Thus, their indications of use have been widened, making the technique more and more well-known and widespread. Therefore, the aim of this study is to present a literature review on comparative studies of the mechanical properties of ceramic systems produced by CAD / CAM. A search for scientific articles published between 2009 and 2019, in English, Spanish or Portuguese, was performed through the databases SCIELO, BIREME and PUBMED, using the descriptors “Ceramics”, “Computer Aided Design” and “ Partial Fixed Prosthesis “. Currently, all ceramic systems appear to have adequate strength for simple rehabilitations, but ceramic restorations produced by CAD/CAM systems present greater reliability than other manufacturing methods, presenting a wider array of indications due to their higher mechanical resistance. These systems, besides their versatility, also present an excellent aesthetic result, guaranteeing appropriate optical properties such as translucency and fluorescence, similar to natural teeth. Although the cost is a limiting factor, CAD/CAM technology is in full development and with high success rates that qualifies it as the state of art in oral rehabilitation.