Examine Gender Differences Research Articles

Abstract 4122590: Sex Differences in the Prescription of P2Y12 Inhibitor Agents Following Percutaneous Coronary Intervention

Background: There remain significant gender inequalities in the delivery of healthcare. Third generation P2Y12 inhibitors (P2Y12i), Prasugrel and Ticagrelor, are the standard of care for dual antiplatelet therapy (DAPT), especially in the setting of acute coronary syndrome (ACS). We hypothesized that women are less likely to be prescribed 3 rd generation P2Y12i than clopidogrel, due to concealed gender inequalities. Methods: We examined gender differences in post percutaneous coronary intervention (PCI) care in a cohort of 12,354 PCI cases from all 14 hospitals within the Steward Health Care system in the United States of America (USA). After removal of duplicates, 10,415 patients were included in the final analysis, with 7,191 males (69.04%) and 3,224 (30.96%) females. We conducted statistical analyses using the Chi-Square test of independence to explore associations between categorical variables, and logistic regression analysis to model the probability of clopidogrel prescription based on patient characteristics, adjusting for confounders. Results: We found that women were less likely than men to be prescribed 3 rd generation P2Y12i compared to clopidogrel with an odds ratio (OR) of 0.74 (CI 0.69-0.80, p<0.001). We adjusted for the following variables: age, weight, insurance type, number of stents, and relevant co-morbidities. The association remained significant with an OR of 0.83 (CI 0.76-0.90, p<0.001). In a subgroup of ACS patients, the association was also statistically significant with an OR of 0.77 (CI 0.67-0.88, p<0.001). Conclusions: Our study reveals that significant gender disparities exist in the prescription of P2Y12i after PCI, with women having a greater likelihood of being prescribed clopidogrel compared to more effective and guideline directed, 3 rd generation agents. This association held true after accounting for confounding variables including older age and an increased prevalence of co-morbidities in the female group. Our conclusions are likely to have been influenced by unmeasured socioeconomic factors, such as household income and medication costs. Therefore, further research ought to be conducted to better understand the reasons behind the association observed.

Relationships Among Physician Vendor-Derived Proficiency Score, Gender, and Time in the Electronic Health Record

Background and Objectives: Electronic health record (EHR) customization is proposed to mitigate EHR-related burnout. Gender disparities in EHR usage are established, though less is known regarding differences in customization and its impact on EHR time. This study examined gender differences in vendor-derived proficiency score (PS) and its relationship to EHR time. Methods: This was a retrospective observational study of ambulatory EHR use for adult primary care and medical subspecialty physicians at an academic safety-net health care system. The EHR vendor provided a physician PS (0–10), derived from customization and efficiency tool utilization. Primary outcomes were PS, time in system per day, and time in system per appointment stratified by gender. We used multiple variable linear regression to determine whether gender differences persisted with the inclusion of other factors. Results: A total of 228 physicians were included in the study; 122 were women, and 106 were men. Women had higher median PS (7.6 vs 6.6, P=.021) and EHR time per day (150.5 vs 119.9 minutes, P=.013), but no difference in time per appointment (24.7 vs 26.1 minutes, P=.665). After adjusting for potential confounders, gender remained a significant predictor of PS, but not time in EHR. Higher PS was significantly associated with greater time in the system per appointment, but not per day. Conclusions: While women had higher PS than men, gender was not significantly associated with measures of EHR time after adjusting for potential confounders. Higher PS was associated with greater time in the EHR per appointment, suggesting factors that influence EHR time are complex and varied.

Abstract 4141480: Gender differences in bifurcation percutaneous coronary interventions: Update from the Prospective Global Registry for the Study of Bifurcation Lesion Interventions (PROGRESS-BIFURCATION)

Background: Gender differences on short and long-term outcomes following bifurcation percutaneous coronary intervention (PCI) have received limited study. Research Questions: To examine gender differences in outcomes of bifurcation PCI. Methods: We examined the angiographic, procedural characteristics, and outcomes of 1084 bifurcation PCIs (1076 patients) performed at five centers between 2013-2024 from the Prospective Global Registry for the Study of Bifurcation Lesion Interventions (PROGRESS-BIFURCATION). Results: Women represented 25.19% of the entire study population. They were older (68.37±12.34 vs 66.09±11.54; p=0.001), less likely to be currently smokers (13.7% vs 20.4%; p=0.014), with higher left ventricular ejection fraction (%) (55.46±13.27 vs 53.16±12.55; p<0.001) and lower baseline creatinine (0.85 vs 1.00; p<0.001). Lesion characteristics were mostly similar, with slightly lower proximal and distal main vessel diameter in women. Their proximal main vessel was more likely to be left anterior descending artery (46.5% vs 39.4%; p=0.030) and less likely to be right coronary artery (10.3% vs 16.1%; p=0.030), compared to men. Technical success was similar (94.5% vs 94.6%; p=0.952), while procedural success was lower (89.6% vs 94.1%; p=0.011). In-hospital major adverse cardiac events (MACE) were more common in women (8.5% vs 4.2%; p=0.007), which presented with increased in-hospital mortality (4.1% vs 0.6%; p<0.001), stroke (1.8% vs 0.1%; p=0.005) and bleeding (1.8% vs 0.2%; p=0.013). Their PCIs required equal procedure time, but lower fluoroscopy time, contrast volume and air kerma radiation dose. Female gender was independently associated with higher in-hospital major adverse cardiac events (MACE) (odds ratio (OR) 2.21; 95%CI 1.23-3.95; p=0.008) and lower procedural success (OR 0.56; 95%CI 0.32-1.00; p=0.044). Follow-up data were available for 733 patients (68.12%). The incidence of follow-up MACE was significantly higher in women (hazard ratio (HR) 1.36; 95%CI 1.02-1.81; p=0.038), while on adjusted mixed Cox proportional hazards analysis female gender was associated with higher follow-up MACE (HR 1.58; 95%CI 1.08-2.30; p=0.018). The incidence of follow-up mortality was similar between genders (HR 1.17; 95%CI 0.78-1.77; p=0.45). Conclusions: Bifurcation PCI can be accomplished with high technical success in women, but higher in-hospital and follow-up MACE, compared to men.

Community crime and safety: An investigation of gender differences in the daily stress process.

Few studies have investigated the associations between community crime rates and affective well-being, and how that relationship may differ according to gender. Using data from the National Study of Daily Experiences and the Uniform Crime Reporting Program, the current study examined gender differences between daily affective experiences, crime rates, and perceptions of neighborhood safety. Although feeling unsafe in one's neighborhood was related to worse affective well-being (i.e., higher negative affect/lower positive affect) and larger affective responses to daily stressors, crime rates were not. Women's negative affect was more strongly tied to daily stressors, whereas men's was more strongly tied to lower perceived neighborhood safety. Findings reveal the importance of understanding factors, such as gender, that impact safety concerns beyond that from crime. They also suggest that increasing visibility within communities might dissuade perpetrators and enhance residents' feelings of safety.

Gender differences in the relationship between depressive symptoms and diabetes associated with cognitive-affective symptoms.

Despite the frequent co-occurrence of depression and diabetes, gender differences in their relationship remain unclear. This exploratory study examined if gender modifies the association between depressive symptoms, prediabetes and diabetes with cognitive-affective and somatic depressive symptom clusters. Cross-sectional analyses were conducted on 29 619 participants from the 2007-2018 National Health and Nutrition Examination Survey. Depressive symptoms were measured by the nine-item Patient Health Questionnaire. Multiple logistic regression was used to analyse the relationship between depressive symptoms and diabetes. Multiple linear regression was used to analyse the relationship between depressive symptom clusters and diabetes. The odds of having depressive symptoms were greater in those with diabetes compared to those without. Similarly, total symptom cluster scores were higher in participants with diabetes. Statistically significant diabetes-gender interactions were found in the cognitive-affective symptom cluster model. Mean cognitive-affective symptom scores were higher for females with diabetes (coefficient = 0.23, CI: 0.10, 0.36, P = 0.001) than males with diabetes (coefficient = -0.05, CI: -0.16, 0.07, P = 0.434) when compared to the non-diabetic groups. Diabetes was associated with higher cognitive-affective symptom scores in females than in males. Future studies should examine gender differences in causal pathways and how diabetic states interact with gender and influence symptom profiles.

The impact of cultural values on students’ communication apprehension in online classrooms: The moderating role of gender

In the post-COVID-19 era, online learning has become an integral part of higher education institutions (HEIs). However, limited evidence suggests that communication apprehension (CA) is a core issue in the lack of engagement in online classrooms. This study seeks to investigate how students’ CA dimensions (i.e., communication participation avoidance and low level of communication confidence) can be predicted by their cultural values using horizontal and vertical individualism/collectivism (HVIC) classification. Moreover, this study examines gender differences as a moderator in the relationship between CA and cultural values. This quantitative survey used an online questionnaire for data collection. A total of 498 samples of data were collected From MBA students studying at the seven most prestigious Iranian business schools. The results of data analysis using SmartPLS4 indicated that the CA levels of MBA students are affected by their cultural values in the HVIC classification (excluding vertical collectivism). Additionally, this study revealed that gender plays a moderating role in the relationships between cultural values and CA dimensions. In general, the results indicated that HEIs should foster a culture that supports individualistic values—such as privacy, independency, self-fulfillment, and individual decision-making—in order to lower CA levels among MBA students.

Influence of gender on Behçet's Disease phenotype and irreversible organ damage: Data from the International AIDA Network Behçet's Disease Registry.

Objectives Gender impact on phenotypical expression of Behçet's disease (BD) has been specifically investigated only in a few large-scale studies. The main goal of the study was to examine gender differences in a large cohort of patients affected by BD. Methods Data were retrieved from the International AIDA Network Registry for BD. We assessed differences between males and females in terms of Behçet's syndrome Overall Damage Index (BODI), differences in the disease manifestations at onset and in the cumulative manifestations throughout disease course, as well as differences in the cardiovascular risk. Finally, predictive factors leading to major organ involvement were investigated. Results In total, 1024 BD patients (567 males, 457 females) were enrolled in the study, with a male-to-female ratio of 1.24/1. Males displayed a significantly higher mean ± SD BODI (1.92 ± 2.09) at the last follow-up, compared to female patients (1.25 ± 1.87) (p<0.0001). Uveitis (p<0.0001) and vascular involvement (p=0.0076) were significantly more frequent among males whereas female patients were significantly overrepresented in arthralgia (p<0.0001), arthritis (p=0.00025), isolated headache (p<0.0001), central nervous system (CNS) involvement (p=0.040), and gastrointestinal involvement (p=0.00046). Regarding cardiovascular risk, no differences between the two groups emerged (p=0.617). Four variables were associated with the development of major organ involvement: male gender (OR=2.104, p=0.001), current treatment with biologic agents (OR=2.257, p=0.0003), origin from endemic countries (OR=2.661, p=0.0009), and disease duration (OR=1.002, p=0.024). Conclusion BD displays a more severe course among males. This subgroup develops more irreversible damage and presents more frequently ocular and vascular involvement during disease course. On the other hand, female patients are prone to experience articular involvement, headache, CNS and gastrointestinal involvement. These data suggest the existence of a gender-driven disease expression.

Cartoon Crime Fighting Groups: Gender, Accuracy, and Motive

ABSTRACT Previous research on depictions of crime in cartoons has focused on violent crimes and psychopathic offenders. However, much of this research has focused on male crime fighters working alone with virtually no studies examining gender differences in crime fighting strategies or motives for offending. We fill this gap in the literature by examining cartoon crime fighting teams and the role gender plays in criminal depictions. Our results show: the presence of female crime fighters (1) generally produced more realistic portrayals of crime, (2) resulted in a range of nonviolent crime fighting techniques, and (3) produced fewer offenders motivated by power.

Longitudinal Changes in Adolescents’ Sedentary, Light, Moderate and Vigorous Physical Activity Levels

Background and purpose: In recent years, sedentary behaviour (SB) has become a significant risk factor for health, alongside the decline of physical activity (PA) in the population. This study explored adolescents’ PA and SB using a longitudinal design, from the age of 13 to 15, to elucidate any changes and when they potentially occur. Method: The data material from the accelerometer measurements was analysed using the program SPSS, version 28. Repeated measures ANOVA (and follow-up test with Bonferroni corrections) were used to assess changes in the four activity levels during the three years. Independent t-tests were used to examine gender differences in each year and at each activity level and to determine differences in activity level between participants with valid data for all three years and those with valid data only at 13 and/or 14 years of age. Results: Statistical analyses of the accelerometer measurements revealed a significant increase in time in the lowest activity level and a decrease in light, moderate and vigorous intensity PA levels during the three years. These changes were larger from 13 to 14, than from 14 to 15, years of age. However, no significant interaction was found between time and gender. Analyses also showed a significantly higher time spent in SB and lower time spent in moderate activity among girls compared to boys at 13, but not at the age of 14 and 15. Conclusions: The findings, which indicate a reduction in PA and increased sedentary time with increasing age, are discussed, which we argue are important to increase and solidify involvement in PA among adolescents. Emphasized here is the importance of communicating the diverse possibilities of movement and challenging understandings of what PA can be for youth.

Gender differences in weight-adjusted waist index in elderly inhabitants of a geriatric center.

Weight-adjusted waist index (WWI) represents a novel anthropometric measure for assessing obesity. Bearing in mind that there is insufficient data in the literature regarding gender differences in WWI values, the aim of the current study was to examine gender differences in WWI values among older adults.

Can’t stop scrolling! Adolescents’ patterns of TikTok use and digital well-being self-perception

Digital well-being, which refers to a balanced individual experience of digital consumption, has been gaining attention recently in the study of the effects of digital technology use. Social networks are central in debates over digital well-being, as social media overuse is often identified as a primary issue. Teenagers who spend an average of three hours daily on social media especially draw the attention of researchers. Based on statistical evidence, TikTok is the most popular network among young users worldwide. However, there are not many platform-specific studies on its effects on adolescent well-being. One of the most consistent gaps is the lack of research on how different aspects involved in TikTok use impact adolescents’ digital well-being on the app. In light of this, the study aimed to explore the relationship between time spent on TikTok, content consumption, and self-perception of digital well-being. Given the scientific consensus on social media’s greater impact on girls, this study also sought to examine gender differences. For that purpose, a quantitative cross-sectional study was conducted with 737 Spanish adolescents aged 12 to 18, who completed an online questionnaire with validated scales and items on daily usage time, type of content consumption, and digital well-being. Results showed significant gender differences in TikTok usage and content consumption: girls spent more time on TikTok and notably engaged more with beauty and fashion content, while boys with video games and sports content, suggesting that traditional gender roles are still present in their choices of content consumption. Beyond that, a rather positive self-perception of digital well-being on TikTok by teenagers was observed. Despite this, an increased TikTok usage was associated with a reduced ability to set boundaries and limit their time on the app. These findings highlight the need for measures to limit the time adolescents spend on TikTok, such as mandatory parental controls on electronic devices and educational programs aimed at promoting healthy digital habits.

Gender differences in the treatment with PCSK9 monoclonal antibodies real world experience from a dedicated prevention clinic

Abstract Background Proprotein convertase subtilisin/kexin type 9 monoclonal antibodies (PCSK9 mAb) lower low-density lipoprotein cholesterol (LDL-C) levels and reduce atherosclerotic cardiovascular disease (ASCVD). There are gender differences in PCSK9 biological characteristics, which are not properly addressed in current data. Purpose Examining gender differences in treatment with PCSK9 mAb. Methods A retrospective study based on data from the Prevention Cardiology Clinic in Rabin Medical Center. Included were patients prescribed with PCSK9 mAb (evolocumab or alirocumab), for primary or secondary prevention. Data included medical background and treatment variables. Response to treatment was evaluated by changes in LDL-C at 3 and 12 months. Data was analyzed by gender. Results Study included 246 patients (mean age 67y, ASCVD 78.8%, mean baseline LDL-C 128.2 mg/dL). Women (42% of cohort) prescribed with PCSK9 mAb were older than men (69 vs. 65 years, respectively; p&amp;lt;0.001). The dominant indication for PCSK9 mAb for both genders was secondary prevention, while primary prevention indication was more prevalent in women vs. men (39.4% vs. 16.3%, respectively; p&amp;lt;0.001). Statin intolerance was observed in 82.4% and 58.6% were treated with combination therapy with PCSK9 mAb, without significant gender differences. Baseline mean LDL-C was higher among women vs. men (138.9 vs. 117.3 mg/dL; p&amp;lt;0.001). Overall, high adherence was observed (91.8% and 79.7% at 3 and 12 months, respectively). After 1-year, adherent men had lower LDL-C levels than women (46.8 mg/d and 61.9 mg/dL, respectively; P=0.001), and were more likely to reach their LDL-C therapy goals; below 70 mg/dL (76.1% vs. 62.2%, respectively; P=0.032) and below 55 mg/dL (60.1% vs. 39.8% respectively; P=0.003). Conclusions In patients treated with PCSK9 mAb, gender differences exist in prescription age, indications, baseline LDL-C and achieved LDL-C goals. In this study adherence to PCSK9 mAb was higher than reported before, possibly due to surveillance in a dedicated prevention clinic.LDL-C &amp; Non-HDL-C levels under PCSK9 mABSex Differences in acheived LDL-C goals

Navigating the social media landscape: unraveling the intricacies of safety perceptions

The emergence of social media has greatly enriched the channels and sources of information through which individuals interact. However, there remains a lack of empirical research on its actual impact on personal safety. This study employed both Structural Equation Modeling (SEM) and network analysis to explored the mechanisms by which social media engagement affects safety perceptions. Additionally, it examined gender differences from both micro-level perspectives (including general trust and perceived social support) and macro-level viewpoints (including personal belief in a just world). The findings revealed that perceived social support, general trust, and personal belief in a just world played a fully mediating role. A multi-group analysis indicated that males were more susceptibility to the influence of social media engagement, with their general trust exhibiting negligible impact on perceived safety. Consequently, this study argues that attention should be given not only how social media affects personal beliefs and safety perceptions, but also its impact on behavioral outcomes.

Health Behavioural Status of Gender Differences in Older People

Aging is a universal phenomenon with no single definition, varying across cultures, time, and space. The health and well-being of older adults are significantly influenced by their behaviors, which often vary by gender. These differences can impact physical health, mental health, and overall quality of life. This study explores the health behavioral status of older adults, focusing on gender differences and how these disparities affect their health indicators. Such changes impact the health status of older people, making it harder for them to manage daily tasks and access healthcare. Conducted in Dhangadhi Sub-Metropolitan City, Kailali District, Nepal, this study aims to understand the socio-economic and health status of older people. Objectives include examining gender differences in health behavior among the elderly in this region. Gender differences in health behaviors among older adults significantly impact their health. Women engage more in preventive behaviors and seek healthcare services, while men engage in riskier behaviors and underutilize services. Understanding these differences is crucial for developing effective, gender-specific interventions to improve older adults' health and well-being. Gender differences were significant, with males showing a higher percentage of better health compared to females, and females showing slightly higher rates of bad health compared to males. Vision problems were prevalent, with a majority reporting no issues, some reporting minor problems, and a smaller portion having normal vision. Significant vision problems were reported by a notable fraction of respondents. Respiratory diseases were more prevalent among males than females, indicating a significant gender association. Gout or knee pain was more common in females than males, also showing a significant gender difference. Diabetes affected a larger portion of males compared to females, indicating a significant gender association. Blood pressure issues were slightly more prevalent in males compared to females, showing a significant gender association. Emotional health conditions such as grief, depression, and sadness showed significant gender differences, with females more likely to experience these issues.

Gender Differences in Co-developmental Trajectories of Internalizing and Externalizing Problems: A 7-Year Longitudinal Study from Ages 3 to 12.

The co-occurrence of externalizing and internalizing problems is acknowledged, but gender differences remain unclear. The present study examines gender differences in the longitudinal relationships between conduct and emotional problems throughout childhood. The sample, drawn from the ELISA project, included 2368 children (48.1% girls; ages 3-12). Latent growth curve models were employed to analyze the trajectories of parent-reported conduct problems and emotional symptoms separately, while parallel process latent growth curve models were utilized to compare joint trajectories. The decrease in conduct problems was consistent for girls, but not for boys. High initial emotional symptoms predicted a slower increase in emotional symptoms over time for girls. Parental positivity was a protective factor for conduct problems in girls. Grandiose-deceitful traits were more related to conduct problems in girls, while callous-unemotional traits were related to emotional symptoms in boys. This study highlights the importance of considering gender in childhood conduct and emotional problems.

An exploratory study of resettled Rohingya refugees: Healthcare access and preventive cancer screenings.

Research suggests that preventive healthcare needs are high among U.S. refugees from Myanmar; yet no studies have examined healthcare patterns among U.S. Rohingya refugees. We examined participation in preventive cancer screening, healthcare access barriers, and facilitators in a community-based sample of 308 Rohingya refugees in Chicago, Illinois. Descriptives were conducted for the participation rates to preventive cancer screenings, indicated by age and gender. Chi-square tests were used to examine gender differences in barriers and facilitators in healthcare. Participants reported low participation in preventive screenings (e.g. 89.2% never received a Papanicolaou (pap) test). Healthcare access barriers were observed: 82.8% uninsured, 81.2% not knowing where to go for healthcare needs, and 55.1% needed interpretation, with men less likely to have had a doctor's visit in the past year or a regular provider. Findings highlight the urgent need to further develop or tailor interventions to address the healthcare needs for resettled Rohingya refugees.

A Multi-site Examination of Relationship Violence Intervention Program Attrition for Male and Female Clients

The current study addresses the paucity of research on relationship violence intervention program (RVIP) attrition examining both male and female clients and risk factors for attrition across gender. Bivariate comparison tests and logistic regression were used to examine gender differences among participants from four RVIPs in Maryland that serve both male and female clients ( n = 1,307). Findings showed significant bivariate differences by gender for 14 of the factors examined. Less than half of clients (48%) completed RVIP, and women were significantly more likely to complete than men. A greater number of factors predicted attrition for male clients, but unemployment was the strongest predictor of attrition for both men and women. Implications for integrating gender-responsive practices into RVIP are discussed.

Gender Differences in Variability in Intimate Relationship Satisfaction: A Secondary Analysis and Meta-Analysis.

There is a long-standing interest in gender differences in satisfaction in intimate relationships. Whereas prior research has focused on gender differences in central tendency (i.e., means), we conducted two studies - a secondary analysis of data from a probability sample of Australian married couples and a meta-analysis - to examine gender differences in variability (i.e., variances). We hypothesized that compared to males, females would demonstrate greater variability in intimaterelationship satisfaction (i.e., greater female variability hypothesis), particularly at lower levels of relationship satisfaction. Results from a secondary analysis of data from 2,711 married couples in the Household, Income and Labour Dynamics in Australia (HILDA) survey and from a meta-analysis of 20 years of research (k = 171, N = 84,976), including independent samples from 33 countries, indicated that relative to males, females reported greater variability in relationship satisfaction. Obtained effect sizes (female-to-male variance ratios [VRs] of 1.42 for the HILDA sample and 1.19 for the meta-analysis) were larger than proposed cutoffs for meaningful group differences in variability. Analysis of tail ratios (ratios of the relative proportion of females divided by the relative proportion of males in the distributional tail regions) in the HILDA sample indicated that gender differences in variability were greater at lower (versus higher) levels of satisfaction. Findings support the greater female variability hypothesis and suggest that by focusing only on gender differences in means, the existing literature has underestimated gender differences in intimaterelationship satisfaction.

Maternal/paternal helicopter parenting and school adjustment in adolescents: The mediating roles of internal and external academic locus of control

There is little evidence regarding the impact of helicopter parenting (HP) on adolescents’ school adjustment (SA). This study examined gender differences in maternal/paternal HP, internal/external academic locus of control (ALC) and SA, and the mediating effect of internal/external ALC in the relationship between maternal/paternal HP and SA in adolescents. The participants of the study were 447 adolescents. The results revealed no significant gender differences in study variables except for external ALC. Adolescent boys indicated significantly higher levels of external ALC than girls. HP predicted ALC and SA, and internal/external ALC had a mediating role in the relationship between HP and SA. This study provides important insights for researchers and practitioners seeking to understand the effects of maternal/paternal HP on adolescent SA. The results of our study suggest that HP may be associated with lower SA among adolescents and that internal ALC may be a key mechanism in this relationship.

Exploring Climate Change’s Psychological Association, Between Eco-Anxiety, Eco-Grief and Attitude Towards Environment

This study investigates the psychological correlations among eco-anxiety, eco-grief, and attitudes toward the environment within the context of climate change. Data were collected using convenience sampling from a sample size 200 in the Malakand district of Khyber Pakhtunkhwa, Pakistan. The sample included 124 males and 76 females. Data collection involved the Eco-Anxiety Questionnaire comprising 22 items, the Eco Grief Questionnaire consisting of 6 items, and the Environmental Attitude Scale containing 20 items. The Statistical Package for Social Sciences was utilized to conduct correlation and t-tests, assessing the frequencies and percentages of demographics, as well as calculating the mean, standard deviation, reliability, and skewness of variables. The correlation analysis indicated a positive relationship among eco-anxiety, eco-grief, and environmental attitudes. A significant positive correlation was observed between eco-anxiety and environmental attitude (r=0.82, p&lt;0.01), and between eco-grief and environmental attitude (r=0.80, p&lt;0.01). The T-test was utilized to examine gender differences in the experiences of eco-anxiety and eco-grief. The findings demonstrated that females achieved significantly higher scores on the eco-grief scale compared to males. The findings indicate that eco-anxiety and eco-grief play a crucial role in fostering a proactive environmental attitude among adults, revealing notable differences between genders. The research highlights that eco-anxiety and eco-grief can strengthen an individual's emotional connection to nature. This increased connection often leads to a stronger commitment to preservation, thereby fostering a positive environmental attitude.