Evidence-based Medical Practice Research Articles

Simulation-based interprofessional education for teaching evidence-based medical practice.

Objective: To achieve consensus on opinions of expert medical educationist on utilization of simulation-based interprofessional education as teaching strategy for evidence based practice teaching in undergraduate medical education. Study Design: Qualitative Case study. Setting: Bahria University Health Sciences Campus. Period: March 2023 to August 2023. Methods: Research using modified Delphi technique was done under ERC 16/2023-BUMDC. Communities of practice and transformative learning theory were used for guiding research design. Non-probability, snow-ball sampling technique was used to select expert panel as participants. Inclusion criteria were medical educationist with masters in health professional education and ten year of experience in department of medical education. Content analysis was used for analyzing data and atlas ti-9 was used for organizing data collected through online email interviews. Results: Final consensus of participants was attained on, third year, Simulation-based interprofessional education/ Assignments/ Journal Clubs/Case-based discussions, Fourth year, Simulation-based interprofessional education/ Journal Clubs/Case-based discussions, Content: Final year, Simulation-based interprofessional education/ Clinical setting/ Journal Clubs. Conclusion: Expert showed ninety percent consensus that simulation-based interprofessional education is good teaching strategies for teaching evidence –based practice in undergraduate medical.

A Multi-Objective Approach Optimizing Pharmacy Industry Decisions through MOORA Method

The pharmacy industry, a crucial pillar of the healthcare sector, encompasses the discovery, development, production, distribution, and sale of pharmaceutical drugs and medications. With an intricate interplay of scientific innovation, medical expertise, and commercial activities, this industry plays an indispensable role in safeguarding and improving human health. From the inception of groundbreaking drugs to their widespread distribution, the pharmacy industry integrates various stakeholders, including pharmaceutical companies, researchers, healthcare professionals, regulators, and consumers. It strives to address a wide spectrum of health conditions, from acute ailments to chronic diseases, by developing innovative treatments, generic medicines, and over-the-counter drugs. The pharmacy industry's evolution has been marked by technological advancements, research breakthroughs, and regulatory frameworks to ensure drug safety and efficacy. As the global population continues to grow and age, the industry faces the challenges of maintaining affordability, accessibility, and quality of medications. Furthermore, the pharmacy industry is a catalyst for economic growth, creating jobs, fostering research collaborations, and contributing to national and international healthcare systems. Its multifaceted nature, ranging from drug research to patient care, underscores its significance in the broader landscape of healthcare and public well-being. Research within the pharmacy industry holds immense significance due to its pivotal role in advancing medical knowledge and improving patient outcomes. Pharmaceutical research drives the development of new medications, innovative therapies, and treatment protocols, enhancing the efficacy and safety of drugs. It also uncovers insights into disease mechanisms, fostering a deeper understanding of health conditions. Furthermore, research guides regulatory decisions, ensuring drugs' quality, and promotes evidence-based medical practices. Through ongoing investigation, the pharmacy industry continually evolves, addressing emerging health challenges, optimizing drug utilization, and ultimately contributing to the overall enhancement of global healthcare standards. MOORA (Multi-Objective Optimization by Ratio Analysis) is a decision-making method used to evaluate and prioritize alternatives based on multiple conflicting criteria. It involves comparing alternatives' performance ratios against reference alternatives, considering both benefits and drawbacks. By assigning weights to criteria, MOORA quantifies their importance and ranks alternatives accordingly. This technique assists in complex decision scenarios where various factors must be balanced. MOORA's systematic approach aids in reaching well-informed decisions by quantifying trade-offs and providing a structured framework for considering multiple objectives simultaneously. Product Innovation, Market Share (%), Research Investment ($ billion), Patient Satisfaction, Drug Efficacy (%), Global Reach (countries). Pfizer, Johnson & Johnson, Roche, Novartis, GlaxoSmithKline, CVS Health, Walgreens Boots Alliance, Rite Aid.From the result it is seen that Novartisis got the first rank where as is the Rite Aidis having the lowest rank.

The Buzz Surrounding Precision Medicine: The Imperative of Incorporating It into Evidence-Based Medical Practice.

Precision medicine (PM), through the integration of omics and environmental data, aims to provide a more precise prevention, diagnosis, and treatment of disease. Currently, PM is one of the emerging approaches in modern healthcare and public health, with wide implications for health care delivery, public health policy making formulation, and entrepreneurial endeavors. In spite of its growing popularity and the buzz surrounding it, PM is still in its nascent phase, facing considerable challenges that need to be addressed and resolved for it to attain the acclaim for which it strives. In this article, we discuss some of the current methodological pitfalls of PM, including the use of big data, and provide a perspective on how these challenges can be overcome by bringing PM closer to evidence-based medicine (EBM). Furthermore, to maximize the potential of PM, we present real-world illustrations of how EBM principles can be integrated into a PM approach.

Application of the MMPI-2 inventory in the differential diagnosis of psychotic disorders – based on profile analysis of a patient diagnosed with persistent delusional disorder and personality disorder

Aim: Paranoid states or traits can be present in various mental disorders; hence, their clarification is valuable for establishing a reliable nosological diagnosis. Clinical practice and literature on the subject highlight a range of defence mechanisms specific to the discussed nosological group. These mechanisms can impede the process of psychiatric and psychotherapeutic diagnosis and treatment. In contemporary evidence-based medical practice, the prevalent clinical approach is based on qualitative methods (e.g. free interviews and observations) complemented by standardised diagnostic tools. This approach assists the clinician in supplementing, organising, and objectifying clinical data related to the patient’s mental state. It is particularly beneficial for handling data that may be uncertain or unavailable in an observational study for various reasons. The article presents insightful and pragmatic theoretical, empirical, and case-related information on the potential application of the Minnesota Multiphasic Personality Inventory (MMPI-2) in the psychological diagnosis of patients with persistent delusional disorders. Methods: The paper explores theoretical issues and analyses a case study involving a female patient with a suspected diagnosis of delusional disorder and co-occurring personality disorder. In the case study, the authors employed qualitative methods, including observation and free psychological interview, and supplemented clinical data with insights gained through the use of a standardised psychometric method: the MMPI-2. Reflections and practical recommendations are divided into two groups. One group comprises the potential applications of the MMPI-2 in clinical psychological diagnosis. The other focuses on the importance of the diagnostic alliance and its roles in the process of planning the psychological diagnosis in patients with delusional disorders.

Collaborative governance in integrated healthcare networks: insights from the cancer program in Québec (Canada)

Context: The challenge of modernizing health services delivery for cancer patients and their loved ones involves moving towards integrated network-based practices. While initiatives at different levels of healthcare systems contribute to this movement, further efforts are needed to maintain and extend gains to adapt to the complex and fast-changing cancer environment. A collaborative governance regime, understood as a form of capacity building for joint action across boundaries, represents a promising way to improve and sustain integrated care.
 Objective: This presentation reports insights from providers and users of health services gained from the experience in operationalizing an integrated network-of-networks in the context of a national cancer program in Quebec (Canada). 
 Methods: Methods: Insights are drawn from a larger multiple case study that took place from 2018 to 2021. Participants (n=39) are knowledgeable informants on how “mandated” integration structures and processes support collaboration among the various components of the network. Documents (n=45) related to network governance and integrated practices are also included. The data collection guide and analysis based on qualitative interpretive description are framed on the Collaborative Governance framework to capture critical dimensions in the integration process. These include clear mission, common and shared definition of complex problems and potential solutions, and identification of common values to support motivation, engagement and capacity for joint action.
 Results: We report on three main tensions related to integration in the cancer network that suggest strategies for enhancing collaborative governance: 
 The first tension emerges as some participants perceive “mandated integration” within a “prescribed collaborative work” as a constraint that undermines previous collaborative work at local level. This tension leads to unresolved controversies within and between actor groups, weakening the mechanisms of collaborative governance. 
 The second tension is a principle-to-practice divide around engaging people affected by cancer in network governance. Despite widespread motivation, participation at the local level varies according to managers' willingness and skill in creating open and inclusive processes where evidence-based medical practice and lived patient experience can be assembled. This tension is seen to contribute to a poor consideration of patient perspectives during the highly volatile period of decision-making during the COVID-19 pandemic.
 The third tension involves the hierarchy of cancer services promoted in the national cancer program and the standardization of practices. Organizing the network-of- networks by cancer specialization involves creating trajectories by type of cancer and their navigation according to established standards of practice and quality considerations. The consequent redistribution of human and financial resources, and revised ownership of care process creates perceived asymmetries between cancer network professionals and centers and controversies that hinder integrated practices. 
 Conclusion: Despite favorable starting conditions from the national cancer program and its central leadership promoting collaborative governance, tensions that emerge through the pursuit of network integration limit the transition to a more collaborative regime. Taking the time to work out these tensions as integration proceeds appears essential to arrive at a governance model that is appropriate and acceptable for all network members.

Shared decision-making in pediatric palliative care

Shared decision-making (SDM) with parents and adolescents is normative in pediatric practice in North America. In this article we discuss how it is applicable to the practice of pediatric palliative care (PPC). As PPC itself is exemplary of patient-and-family-centered care, it often uses a SDM approach in clarifying patient and family preferences, goals, and values. This often occurs in an iterative process and across care environments, wherein the patient and family narrative is elaborated. Decisions are then made incorporating both evidence-based medical practice and the unique attributes and considerations of the patient and family.

11. ENHANCING EVIDENCE-BASED MEDICINE COMPETENCE IN THIRD-YEAR STUDENTS THROUGH BASIC SCIENCE RESEARCH TRAINING: OUTCOMES AND FINDINGS

Background: In 2022, for the first time, the Faculty of Medicine, Dai Nam University applies scientific research methods to 3rd year medical students.
 Objective: To evaluate the impact of the Medical Scientific Research Methods module on medical students’ skills and knowledge.
 Methods: This pre-test post-test pilot study used a prospective descriptive exploratory method by non-probability convenience sampling of all people participating in the course “Medical science research methods,” which was compulsory for 3rd-year medical students, Faculty of Medicine, Dai Nam University, from August to December 2022. The study invited a total of 89 students from two classes to participate. At the beginning of the course, 82 students completed the survey, while 66 students responded to the second survey after completing the course.
 Result: This study demonstrated that an undergraduate research methods course had a meaningful impact on medical literature search behaviors, understanding of medical research terminology, and confidence in evidence-based medical practice among students. However, despite these positive results, the knowledge and skills of students in evidence-based medicine were limited.
 Conclusion: The scientific research methods course has significantly improved students’ EBM knowledge and skills, albeit with some limitations. However, this study highlights the need for continued training programs and practical experience in medical research to enhance further and maintain learners’ proficiency in EBM.

Effectiveness of platelet transfusion in dengue fever: Rangpur community medical college and hospital experience at Rangpur, Bangladesh

Background: Dengue fever, caused by the dengue virus and transmitted by mosquitoes, is a global health concern, causing mild to severe illness. Severe cases lead to thrombocytopenia, a low platelet count that can cause bleeding. Platelet transfusion is debated as a treatment strategy; some studies support its use to prevent bleeding, while others raise concerns about side effects. The aim of the study is to see the effectiveness of platelet transfusion in dengue patients who has a very low platelet count. Methods: This single-center study was conducted at The Department of Medicine, Rangpur Community Medical College and Hospital, Bangladesh. A total of 52 patients were enrolled and analyzed in this study from March to August 2023. Results: Most cases are Dengue Fever (86.54%), followed by Dengue Hemorrhagic Fever Grade 1 (7.69%) and Dengue Shock Syndrome (5.77%). Bleeding occurred in 15.38% of enrollment. Common symptoms include fever (78.85%), headache (57.69%), cough (67.31%), and myalgia (55.77%). Health parameters include blood pressure (110/70 mm Hg), pulse rate (86.5±12.8 bpm), and temperature (100.5±2.8°F). Investigation findings show S. bilirubin (0.61 mg/dl), S. creatinine (0.94 mg/dl), RBS (120.5 mg/dl), HB% (13.78 g/dl), and PCV (39.75). Platelet counts varied in different conditions, with most responders to platelet transfusion (94.23%) showing no deaths but adverse outcomes related to transfusion reactions (5.77%). Conclusions: The prevalence of dengue fever in Bangladesh necessitates a comprehensive understanding of effective treatment modalities. By examining the outcomes and implications of platelet transfusion in this context, the research seeks to shed light on its effectiveness, thereby informing evidence-based medical practices and improving patient care.

The global health and economic impact of low-back pain attributable to occupational ergonomic factors in the working-age population by age, sex, geography in 2019.

Occupational ergonomic factors (OEF) include physical exertion, demanding posture, repetitive work, hand-arm vibration, kneeling or squatting, rising, and climbing, which are risk factors for low-back pain (LBP). This study aimed to examine the prevalence, years lived with disability (YLD), healthcare costs, and productivity losses of LBP attributable to OEF by age, sex, World Health Organization region, and country in 2019. In this cross-sectional study, prevalence and YLD were extracted from the Global Burden of Diseases, Injuries, and Risk Factors Study 2019. Employment statistics were obtained from the International Labor Organization websites. Health and economic impact was estimated for 192 countries and territories using the population attributable fraction method. Globally, OEF were responsible for 126.1 million prevalent cases of LBP and 15.1 million YLD in the working-age population (aged 15-84 years) in 2019, with the Western Pacific region suffering most. OEF-attributable LBP led to $216.1 billion of economic losses worldwide. Of these, $47.0 billion were paid in healthcare costs, with the public sector serving as the largest contributor (59.2%). High-income countries bore >70% of global economic burden, whereas middle-income countries experienced >70% of global YLD. Generally, more prevalent cases and healthcare costs were found among females, whereas more YLD, productivity losses, and total costs were found among males. Globally, OEF-attributable LBP presented a heavy burden on health and economic systems. Exercise together with education, active monitoring, evidence-based medical practices, alternative cost-effective solutions, and prioritizing health policies are needed.

Validation of a human paper-based blood typing method for use in pet pigs.

Evidence-based medical practices for pet pigs are needed. EldonCard is a human blood-typing card shown to be rapid and reliable in identifying blood phenotypes of pet pigs. The objective of this study was to validate EldonCard by determining its reliability, reproducibility, and robustness for its routine use in the clinical setting. Twenty-four venous blood samples from pet pigs were collected for a prospective in vitro study. Blood genotypes ("EAAA0 " and "EAA00 ") were identified in 15 samples via polymerase chain reaction (PCR). All samples were phenotyped ("A," "Aweak ," and "0" or "-") via EldonCard. Kappa (κ) statistics measured the level of agreement between 2 raters, and between EldonCard and PCR. McNemar's test determined if an association between the blood types and EldonCard or PCR exists, with significance at P<0.05. Agreement between raters and methods was perfect (60/60 [100%], κ:1, P<0.001; 15/15 [100%], κ:1, P<0.001). There was no difference in the proportions of blood groups based on method. In conjunction with previous data, EldonCard is a rapid, accurate, reliable, precise, and robust in-clinic blood-typing method for the A0 system of pet pigs. EldonCard is now a validated blood-typing tool for the A0 system of pet pigs and maybe used for pretransfusion screenings and identification of donors and recipients.

The Reference Class Problem and Probabilities in the Individual Case: A Response to Fuller

AbstractIn a recent article on the interpretation of probability in evidence-based medical practice, Jonathan Fuller argues that we should interpret probabilities as credences in individual cases because this avoids some important problems. In this article, I argue that Fuller misidentifies the real issue and so fails to offer a meaningful solution to it. The real problem with making probability judgments in individual cases is deciding which objective considerations ought to constrain our formation of credences. This leads us to the reference class problem, which, as Alan Hajek argues, is a problem for any interpretation of probability.

Systematic Appraisal of the Impacts of Transformational Leadership on Innovation Behaviour Among Nurses

Background: The healthcare industry is among the most essential in any economy. The challenges that confront the sector are wide and far-reaching. Given the economic challenges that are unpredictable and difficult to plan for, the healthcare sector is facing a host of challenges. This study aims to explore the important role of transformational leadership that can inspire innovative work behaviour of nurses to perform their tasks most efficiently.&nbsp; Method: the initial online database search for relevant literature yielded 4160 papers from two databases. After excluding duplicates and those for which full texts were not available, and other exclusion criteria, six papers were selected for extraction of results. First, rating of the quality of these papers was done adapting the CASP model for one qualitative review and Axis analysis for five papers. In depth analysis of six papers was further done are results presented for discussions. Results: A few critical issues emerged which were considered in the discussions of these findings. Considered along with works reviewed in the Review of Literature chapter, the outcome of the work led to some useful conclusions that there is a correlation between transformational leadership and innovative work behaviour among nurses. There is sufficient evidence from the six papers analysed on a positive relationship between transformational leadership and nurse innovation behaviour amid certain mediating factors. Conclusion:&nbsp;&nbsp; More nurse innovative approaches need to be directly applied to achieve the triple aim of care quality, service, and affordability across all health care organisations in the ever-changing scenarios of evidence-based medical practices.

Guidelines and evaluation of clinical explainable AI in medical image analysis.

Explainable artificial intelligence (XAI) is essential for enabling clinical users to get informed decision support from AI and comply with evidence-based medical practice. Applying XAI in clinical settings requires proper evaluation criteria to ensure the explanation technique is both technically sound and clinically useful, but specific support is lacking to achieve this goal. To bridge the research gap, we propose the Clinical XAI Guidelines that consist of five criteria a clinical XAI needs to be optimized for. The guidelines recommend choosing an explanation form based on Guideline 1 (G1) Understandability and G2 Clinical relevance. For the chosen explanation form, its specific XAI technique should be optimized for G3 Truthfulness, G4 Informative plausibility, and G5 Computational efficiency. Following the guidelines, we conducted a systematic evaluation on a novel problem of multi-modal medical image explanation with two clinical tasks, and proposed new evaluation metrics accordingly. Sixteen commonly-used heatmap XAI techniques were evaluated and found to be insufficient for clinical use due to their failure in G3 and G4. Our evaluation demonstrated the use of Clinical XAI Guidelines to support the design and evaluation of clinically viable XAI.

Zdravlje u funkciji promocije fitnesa u Srbiji

Physical exercise is crucial for maintaining good health and well-being. Scientific research on the impact of physical exercise on health is fundamental for advancing our understanding of the subject, informing public health policies, promoting evidence-based medical practices, and ultimately improving the health and well-being of individuals and communities. The basic goal of this research is to determine the relevance of the term health as a carrier of a promotional message on the fitness market in the Republic of Serbia. The paper used descriptive statistics to describe the sample, T test of independent samples, one-factor analysis of variance (ANOVA) and Pearson's correlation analysis to examine the relationship between variables. The research results showed that the primary focus of the promotional message should still be health. Apart from this, the research found that a significant number of fitness centers use Instagram as the primary social network, and that there is great promotional potential in the relationships that develop between employees and service users.

Clinical spotlight intervention to accelerate translation of evidence-based practices in primary care

Evidence-based medical practice is often slow to diffuse into widespread clinical practice. To accelerate translation of updated best practices into clinical care, we developed a quality improvement intervention called the...

Visualization Techniques in Healthcare Applications: A Narrative Review.

Nowadays, healthcare management systems are adopting various techniques that facilitate the achievement of the goals of evidence-based medical practice. This review explores different visualization techniques and their importance in healthcare contexts. We performed a thorough search on databases such as the SLD portal, PubMed, and Google Scholar to obtain relevant studies. We selected recent articles published between 2018 and 2021 on visualization techniques in healthcare. The field of healthcare generates massive volumes of data that require visualization techniques to make them easily comprehensible and to guide their efficient presentation. Visualization in healthcare involves the effective presentation of information through graphics, images, and videos. Big data systems handle a massive amount of information and require visualization techniques to present it in a comprehensible manner. The significance of visualization techniques in healthcare is not confined tohealthcare practitioners and healthcare management butencompasses all the stakeholders; patients can benefit from the visualization of his/her data for a better understanding of their condition.In short, visualization techniques have demonstrated their benefits in the healthcare sectorand can be extended to the payer and the patient. They have also had a positiveimpact on the quality of the healthcare provided as well as patient safety.

Conflict between Science and Superstition in Medical Practices

Superstition is a belief that is not based on scientific knowledge. Traditional healers usually use superstition in their practices to manage human health problems and diseases; such practices create a conflict with the medical profession and its evidence-based practices. Medical professionals confirm that this kind of practice is unsafe as it is performed by untrained people (e.g., traditional healers) utilizing unsterilized instruments within unhygienic environments. Most of the cases eventually develop a variety of complications, which are sometimes fatal. Female genital mutilation, uvulectomy, oral mutilation (tooth bud extraction to cure “Ibyinyo”), and eyebrow incisions are examples of the many different types of superstitious practices which occur commonly in other parts of the world. We describe how these traditional practices of superstition have been and continue to be performed in various parts of the world, their complications on oral and general health, and how such practices hinder modern medical practices and highlight huge inequalities and disparities in healthcare-seeking behavior among different social groups. This paper aims to increase health literacy and awareness of these superstition-driven traditional and potentially harmful practices by promoting the importance of evidence-based medical practices.

Curing the pandemic of misinformation on COVID-19 mRNA vaccines through real evidence-based medicine - Part 2

BackgroundAuthorities and sections of the medical profession have supported unethical, coercive, and misinformed policies such as vaccine mandates and vaccine passports, undermining the principles of ethical evidence-based medical practice and informed consent. These regrettable actions are a symptom of the ‘medical information mess’: The tip of a mortality iceberg where prescribed medications are estimated to be the third most common cause of death globally after heart disease and cancer.AimTo identify the major root causes of these public health failures.MethodsA narrative review of both current and historical driving factors that underpin the pandemic of medical misinformation.ResultsUnderlying causes for this failure include regulatory capture – guardians that are supposed to protect the public are in fact funded by the corporations that stand to gain from the sale of those medications. A failure of public health messaging has also resulted in wanton waste of resources and a missed opportunity to help individuals lead healthier lives with relatively simple – and low cost – lifestyle changes.ConclusionThere is a strong scientific, ethical and moral case to be made that the current COVID vaccine administration must stop until all the raw data has been subjected to fully independent scrutiny. Looking to the future the medical and public health professions must recognise these failings and eschew the tainted dollar of the medical-industrial complex. It will take a lot of time and effort to rebuild trust in these institutions, but the health – of both humanity and the medical profession – depends on it.ContributionThis article highlights the importance of addressing metabolic health to reduce chronic disease and that insulin resistance is also a major risk factor for poor outcomes from COVID-19.

The Association of Attending Physicians' Publications and Patients' Readmission Rates: Evidence from Tertiary Hospitals in China Using a Retrospective Data Analysis.

Background: Physicians play a unique role in scientific and clinical research, which is the cornerstone of evidence-based medical practice. In China, tertiary public hospitals link promotions and bonuses with publications. However, the weight placed on research in the clinician’s evaluation process and its potential impact on clinical practice have come under controversy. Despite the heated debate about physicians’ role in research, there is little empirical evidence about the relationship between physicians’ publications and their clinical outcomes. Method: This paper examines the association of the quantity and quality of tertiary hospitals’ attending physicians’ publications and inpatient readmission rates in China. We analyzed a 20% random sample of inpatient data from the Urban Employee Basic Medical Health Insurance scheme in one of the largest cities in China from January 2018 through October 2019. We assessed the relationship between the quantity and impact factor of physicians’ publications and 30-day inpatient readmission rates using logistic regression. There were 111,965 hospitalizations treated by 5794 physicians in our sample. Results: Having any first-author publications was not associated with the rate of readmission. Among internists, having clinical studies published in journals with an average impact factor of 3 or above was associated with lower readmission rates (OR = 0.849; 95% CI (0.740, 0.975)), but having basic science studies published in journals with an average impact factor of 3 or above was not associated with the rate of readmission. Among surgeons, having clinical studies published in journals with an average impact factor of 3 or above was likewise associated with lower readmission rates (OR = 0.708 (0.531, 0.946)), but having basic science studies published in journals with an average impact factor of 3 or above was associated with higher readmission rates (OR = 1.230 (1.051, 1.439)).

DO INCREASED LEVELS OF TRIGLYCERIDES CONSIST AN INDEPENDENT RISK FACTOR DEFINING THE SEVERITY OF CARDIOMYOPATHY IN T2DM PATIENTS WITH KNOWN HYPERTENSION ?

Objective: The association of diabetes mellitus and heart disease is well established in evidence-based medical practice in our days. Diabetes Mellitus is also associated with various cardiovascular risk factors including hypertension and hypertriglyceridemia. Therefore, the severity of Cardiomyopathy in Diabetics is interdependent among these various risk factors. The aim of this study was to assess that hypertriglyceridemia is an independent risk factor of the severity of cardiomyopathy in T2DM patients with known Hypertension. Design and method: 451 (249male, 202 female) T2DM Hypertensive patients participated on this study. Age range of the patients was between 48–79 years of age. All patients were assessed for cardiac functioning with Echocardiography and Ventriculographies. Severity of Cardiomyopathy was estimated measuring LVEDP with a borderline &gt; 15 mm Hg. TGC were measured in serum blood analysis of patients in SI units. Data were analyzed using ANOVA and logistic regression analysis. Hypertriglyceridemia was analyzed as an independent risk factor. Data is presented as mean ± standard deviation and level of significance was accepted when p &lt; 0.05. Results: Data were analyzed on 451(249 male, 202 female) hypertensive T2DM patients, 91 (20.2%) presented with TGC level of 2.9 ± 0.8 mmol/L, and a LVEDP of 16.2 ± 0.8 mm Hg. 109 patients (24.1 %) with TGC level of 3.6 ± 0.7 mmol/L, and a LVEDP of 17.8 ± 0.9 mm Hg. 132 (29.3%) TGC level of 4.1 ± 0.3 mmol/L, and a LVEDP of 19.4 ± 0.8 mm Hg and 119 (26.4%)patients with TGC level of 4.7 ± 0.6 mmol/L, and a LVEDP of 21.1 ± 0.8 mm Hg. Data Analysis revealed that hypertriglyceridemia p = 0.019 is an independent risk factor of cardiomyopathy in T2DM hypertensive patients and leads in markedly increased Left Ventricular End Diastolic Pressures p = 0.022. Conclusions: Hypertriglyceridemia is an independent risk factor of Cardiomyopathy in Hypertensive T2DM patients.