Life Events Research Articles

Analysis of Children's Development Pathways based on Bronfenbrenner's Ecological Systems Theory

Childhood is a critical stage in human life, during which an individual's cognitive, emotional, social, and physical development progresses rapidly. Early development is not only essential for children's future achievements but also plays a significant role in societal structure, economic growth, and cultural transmission. Promoting the holistic development of children is the responsibility not only of families and educational systems but also of society as a whole. This study, grounded in Bronfenbrenner's Ecological Systems Theory, aims to analyze how various ecological system levels influence children's cognitive, emotional, and social development, and explores the impact of these systems' interactions on overall child growth. The research encompasses the microsystem (e.g., family and school), mesosystem (e.g., family-school interactions), exosystem (e.g., parental socioeconomic status and work environment), macrosystem (e.g., cultural background and social policies), and chronosystem (e.g., significant life events and historical context). The findings reveal that the interactions between these ecological systems play a pivotal role in children's development and influence their holistic development.

Functional Principal Component Analysis for Continuous Non-Gaussian, Truncated, and Discrete Functional Data.

Mobile health studies often collect multiple within-day self-reported assessments of participants' behavior and well-being on different scales such as physical activity (continuous scale), pain levels (truncated scale), mood states (ordinal scale), and the occurrence of daily life events (binary scale). These assessments, when indexed by time of day, can be treated and analyzed as functional data corresponding to their respective types: continuous, truncated, ordinal, and binary. Motivated by these examples, we develop a functional principal component analysis that deals with all four types of functional data in a unified manner. It employs a semiparametric Gaussian copula model, assuming a generalized latent non-paranormal process as the underlying generating mechanism for these four types of functional data. We specify latent temporal dependence using a covariance estimated through Kendall's bridging method, incorporating smoothness in the bridging process. The approach is then extended with methods for handling both dense and sparse sampling designs, calculating subject-specific latent representations of observed data, latent principal components and principal component scores. Simulation studies demonstrate the method's competitive performance under both dense and sparse sampling designs. The method is applied to data from 497 participants in the National Institute of Mental Health Family Study of Mood Spectrum Disorders to characterize differences in within-day temporal patterns of mood in individuals with the major mood disorder subtypes, including Major Depressive Disorder and Type 1 and 2 Bipolar Disorder. Software implementation of the proposed method is provided in an R-package.

Exploring the effect of family function on non-suicidal self-injury among Chinese adolescents in different family socioeconomic status.

Non-suicidal self-injury (NSSI) among adolescents represents an alarming public health concern worldwide. Both family function and family socioeconomic status (SES) were found to play important roles in adolescent NSSI engagement. However, the effects of family function on NSSI among adolescents in different family SES are not well evidenced. This study aimed to explore how family functions (adaptation, partnership, growth, affection, and resolve) affect NSSI among adolescents in different family SES levels. Data used in this study was derived from the Students' Mental Health Network Project (SMHN), a survey conducted among 8,872 pairs of adolescent-caregivers in a city in central China. Socio-demographic characteristics, family function, NSSI, adverse life events, and depressive symptoms were measured among adolescents. Family SES were generated from caregivers self-reported information using principal component analysis. Chi-square test and multivariate binary logistic regression analyses were adopted to analyze the effects of family function on NSSI. It revealed that 10.2% of adolescents reported engaging in NSSI in the past 12 months. Poor family function and high family SES were positively associated with NSSI. Partnership, both adaptation and affection, resolve were NSSI-protective factors for adolescents in low, middle, high family SES, respectively. Efforts to address NSSI should acknowledge the association between family function and NSSI among adolescents in different family SES levels.

Effects of multiple stress events at different stages of life on the incidence of metabolic syndrome

ObjectiveTo investigate the effects of multiple stress events in different stages of life on the incidence of metabolic syndrome (MetS).MethodsMiners from Tangshan, China, were recruited for this study. Workers of the Kailuan Mining Group were evaluated to investigate whether exposure to Tangshan earthquakes during the fetal period in 1976. Adult life events and childhood trauma were assessed separately via the Life Event Scale and Childhood Trauma Questionnaire. The subjects were physically examined and general demographic data such as waist circumference were collected. Blood samples were collected for measurement of metabolic parameters. Corticotropin releasing hormone(CRH) levels was measured by enzyme-linked immunosorbent assay (ELISA). The subjects were divided into four groups according to their exposure to traumatic events in different stages of life: no exposure group, 1-exposure group, 2-exposures group, and 3-exposures group. The incidence of MetS, metabolic parameters and CRH levels in each of the four groups was compared.ResultsIn all, 626 people were enrolled; of these, 183, 262, 150, and 31 were in the no exposure, 1-exposure, 2-exposures, and 3-exposure groups, respectively. A remarkable variation in the incidence of MetS was observed among the four groups (x2 = 16.462, P<0.001). MetS incidence increased with the increasing number of traumatic events, except for in the no exposure group (17.9% in 1-exposure group, 24.7% in 2-exposure group, and 48.4% in the 3-exposure group). Multivariate logistic regression analysis showed that exposure to multiple stress during the fetal, childhood, and adult stages of life represent independent risk factors for developing MetS (OR=3.134, 95%CI=1.042–9.429). Smoking increased the risk of developing MetS (OR=1.809, 95%CI=1.140–2.871).ConclusionsExposure to multiple traumatic events in distinct life stages increases the risk of developing MetS. Smoking is a risk factor for developing MetS.

Deep phenotyping reveals CRH and FKBP51-dependent behavioral profiles following chronic social stress exposure in male mice.

The co-chaperone FKBP51, encoded by FKBP5 gene, is recognized as a psychiatric risk factor for anxiety and depressive disorders due to its crucial role in the stress response. Another key modulator in stress response regulation is the corticotropin releasing hormone (CRH), which is co-expressed with FKBP51 in many stress-relevant brain-regions and cell-types. Together, they intricately influence the balance of the hypothalamic-pituitary-adrenal (HPA) axis, one of the primary stress response systems. Previous research underscores the potential moderating effects these genes have on the regulation of the stressful life events towards the vulnerability of major depressive disorder (MDD). However, the specific function of FKBP51 in CRH-expressing neurons remains largely unexplored. Here, through deep behavioral phenotyping, we reveal heightened stress effects in mice lacking FKBP51 in CRH co-expressing neurons (CRHFKBP5-/-), particularly evident in social contexts. Our findings highlight the importance of considering cell-type specificity and context in comprehending stress responses and advocate for the utilization of machine-learning-driven phenotyping of mouse models. By elucidating these intricacies, we lay down the groundwork for personalized interventions aimed at enhancing stress resilience and individual well-being.

The impact of anger and age on depression

Abstract Object This study investigates the endogenous factors of trait anger and reactive factors of life events in depression, and examines how anger expression and age influences the mechanism of depression. Method Eighty-nine healthy subjects were randomly selected as the reference group, and 115 outpatients with depression formed the control group. Participants completed the Life Events Scale (Selye 1969), the STAXI-2 scale, and the Beck Depression Inventory (BDI). Results The analysis revealed that trait anger significantly mediates the relationship between life events and depression in the control group, with a total effect confidence interval of 0.46 (95% CI 0.11, 0.81) and an indirect effect of 0.12, accounting for 26.09% of the relative mediating effect (95% CI 0.04, 0.29). Conclusion Trait anger has a significant complete mediating effect on depression with life events as mediators in the control group. Furthermore, anger expression and age significantly moderate the mediating effects of life events on depression.

TikTok Shop: Future of E-Commerce? How Can Galderma Leverage Tiktok Shop to Increase its Penetration and Improve its Market Share in Indonesia Skincare Market?

TikTok was introduced to the Indonesian market in September 2017. Upon its launch, TikTok quickly gained popularity among Indonesian users, especially among the younger demographic, for its short-form video content that allowed for creative expression and entertainment. One of TikTok services is TikTok Shop, an integrated e-commerce capabilities directly within the TikTok app, allowing users to browse, purchase, and sell products without leaving the platform. They launch this service in April 2021. The platform introduced features like shoppable videos and live shopping events, where users could interact with influencers and brands in real-time while purchasing products providing a new and engaging way for Indonesian businesses to reach potential customers and boost sales through interactive and entertaining content. Galderma Indonesia Healthcare is one of the leading companies dedicated to advancing dermatology for every skin story. Galderma strategically its positioned in attractive, consumer-driven segments of the dermatology market, characterized by high growth fundamentals supported by science-based product differentiation and premium positioning. One of Galderma’s brands that is available in Indonesia is Cetaphil. Cetaphil products are available in modern retailers with Health & Beauty channel as the top contributor, followed by general trade and pharmacy channel. Even though available, Cetaphil is still low in in skincare category penetration. This study examines the positioning and promotional strategies of Cetaphil on TikTok Shop using qualitative research methods. Primary data was gathered through expert interviews, while secondary data was sourced from internal company reports, previous research studies, and strategic agency reports.

Film intervention increases empathic understanding of formerly incarcerated people and support for criminal justice reform

Nuanced portrayals of stigmatized groups in media have been shown to reduce prejudice. In an online experiment (N = 749), we tested whether a feature film depicting incarcerated peoples' experiences in the criminal justice system can increase a) empathic accuracy and compassion toward people who have been incarcerated and b) support for criminal justice reform. We measured baseline empathic accuracy via a well-validated task, where participants infer the emotions of people sharing stories about difficult life events. All storytellers were formerly incarcerated and students. However, in half the videos we labeled them as "formerly incarcerated" and in the remaining half as "college student." We then surveyed people's baseline attitudes toward criminal justice reform. Next, we assigned participants to watch one of three films. The intervention film chronicled the true stories of Black men on death row. Two docudramas of similar length served as control films. Finally, participants completed the empathic accuracy task and survey again and were given the opportunity to sign a petition. Compared to those who watched a control film, participants who watched the intervention film more accurately inferred the emotions of storytellers labeled "formerly incarcerated," and increased their support for criminal justice reform. These effects held for conservative and liberal participants alike. However, the film had no effect on feelings of compassion. Together, these results demonstrate the power of narrative interventions to not only increase empathic accuracy for members of a severely stigmatized group, but to increase support for reforms designed to improve their lives.

The family as provider of intergenerational support during COVID-19: a study into the mental health consequences for 65+ Europeans

IntroductionIntergenerational support is an important determinant of mental health. Due to limited access to formal care, the role of the family as provider of support became more prominent during the COVID-19 pandemic. To date, it remains unclear how intergenerational support from adult children to older parents was affected during the pandemic and whether this had consequences for the mental health of the parent generation.MethodsUsing data from the Survey of Health, Ageing and Retirement in Europe (SHARE) Corona Surveys, we explore whether changes in support going from non-coresident adult children to their parents are associated with parents’ increase in depressive feelings. Additionally, we test whether the pandemic context and public health measures affected this relationship.ResultsDuring the pandemic, families are found to provide more support. These changes in intergenerational support, however, were related to increased depressive feelings for the older parents. Furthermore, both the strictness of public health measures and the concurrent epidemiological situation affected this relationship.ConclusionWe conclude that the family is an essential source of late-life well-being, but stressful life events, such as public health crises, put pressure on these intergenerational relations with potential adverse mental health outcomes. Future policies should take into account the ambivalent nature of intergenerational relationships.

General Self-efficacy and Other Predictors of Grade Point Average (GPA) in College Students of Kathmandu, Nepal

General self-efficacy refers to individuals' belief in their ability to manage their functioning and influence life events. It can be influenced by various factors such as personal achievements, observed experiences, encouragement, and emotional states. We aimed this study to examine the relationship between general self-efficacy and other demographic factors in predicting Grade Point Average (GPA) among college students. The power analysis indicated minimum of 385 data points for unknown population, however we followed the rules of thumb that more data equals better results. This cross-sectional survey involved 527 college students from the Kathmandu Valley, representing various age groups, genders, ethnicities, religious affiliations, marital statuses, residential locations, education levels, faculties, and years of study. We targeted only two colleges to collect the data; however, the online portal of data collection allowed students to provide the data from other institutions as well. Students were selected through opportunity sampling, and data were collected using the General Self-Efficacy Scale between September 8 and November 2, 2022. Our findings indicate no significant relationship between general self-efficacy and GPA. Ethnicity (Janajati), religion (Buddhists), education level (high school), faculty (management), and institution type (private) were identified as significant predictors of GPA, while gender, age, marital status, and residential location did not predict GPA. The study provides valuable insights into how demographic factors, rather than self-efficacy, influence academic performance, offering useful information for educational strategies aimed at improving student outcomes.

Suicidal behavior among Turkish physicians: Associations with negative life-events, psychological distress, and attitudes towards suicide

BackgroundSuicidal behavior among physicians is a significant concern globally, with various factors contributing to increased risk. Physicians in Türkiye are a group facing significant psychological distress due to challenging work conditions, economic instability, and violence in the healthcare system. Understanding the specific risk factors and attitudes contributing to this elevated suicidal behavior can inform the development of targeted interventions and support mechanisms for improving the well-being of physicians in Türkiye. This study aims to investigate suicidal behavior among Turkish physicians and its associations with adverse life events, psychological distress, and attitudes toward suicide. MethodIn the present study, 512 Turkish physicians from diverse demographics and professional backgrounds participated. Suicidal behavior, psychological distress, stressful life events, and attitudes toward suicide were explored through tailored instruments. Logistic regression analysis was conducted to identify independent risk factors for suicidal behavior. ResultsThe results demonstrated that among Turkish physicians, psychological distress and suicidal behavior were frequent. One in five individuals (22.3%) reported experiencing one of the suicidal behaviors within the past month. Nearly one in ten (8.6%) have attempted suicide at some point in their lives. The average number of suicidal behaviors reported was .48 (SD = 1.1), and the average severity score for suicidal ideation was .51 (SD = 1.2). Young age, single marital status, low social support, psychological distress, the number of stressful life events, and the acceptability of suicide were identified as independent risk factors for suicidal behavior. Having a diagnosis of a psychiatric disorder and the number of stressful life events were factors associated with suicide attempts. ConclusionThe intricate associations between several factors that influence suicidal behavior among Turkish physicians are elucidated by this study. The results highlight the critical need for focused interventions and systems of support within the Turkish healthcare system to deal with this serious public health concern. Future studies and therapeutic practices can better meet the mental health requirements of this vulnerable demographic by considering the complex nature of suicidal behavior among physicians.

Age, Adverse Childhood Experiences, and Health Care Utilization.

To assess whether the association of adverse childhood experiences (ACEs) with pediatric health care utilization differs by age. In this retrospective cohort study, we included patients completing primary care ACEs screening between January 2020 and September 2021. Pediatric ACEs and Related Life Events Screener Part 1 scores were categorized 0, 1 to 3, or ≥4 (none, low, and high, respectively). Two multivariable logistic regression models assessed emergency department (ED) and inpatient utilization across all ages 6 months after screening. Among 37 315 patients, 15.7% visited the ED and 2.5% were hospitalized within 6 months of ACEs screening. Using no ACEs as the reference, infants and toddlers with any ACEs had lower odds of ED and inpatient utilization, whereas older children with any ACEs had higher odds of ED (age-low ACEs: 0.04, P value < .001; age-high ACEs: 0.08, P value < .001) and inpatient (age-low ACEs: 0.06, P value < .001; age-high ACEs: 0.15, P value < .001) utilization and increased each successive year of age. The association of ACEs with health care utilization is dependent on age and is more complex than previously described. These trends may inform specific therapeutic strategies for pediatric patients by age.

Let the Music Play: Live Music Fosters Collective Effervescence and Leads to Lasting Positive Outcomes.

This work examined the power of live music events to enhance wellbeing through collective effervescence (CE)-the sense of sacredness and connection felt when in large groups. Four studies (N = 789) using both university and community samples examined the relationship between live music events and CE and how this relationship contributes to positive, lasting outcomes. Results suggest that CE is highly related to positive outcomes associated with attending live music events. CE uniquely predicted meaning in life and enjoyment during the event above and beyond related constructs. Feeling CE was also related to greater meaning in life during the event and continued happiness a week after live music events. Further, CE mediated effects between various elements of live music events (e.g., parasocial bonds with the artist) and positive lasting outcomes. In summary, CE plays a key role in the lasting wellbeing that follows live music events.

Stressful family life events and father involvement in Korean children's sociobehavioral health.

We examined the longitudinal associations between stressful family life events at 4 years of age and children's internalizing and externalizing behaviors at 7 years of age, whether family functioning and parental warmth (i.e., mothers' warmth, fathers' warmth) mediated those associations, and whether the associations varied by fathers' involvement in Korean families. Participants were 1,703 families, including mothers (Mage = 34 years; SD = 3.70 years), fathers (Mage = 37 years; SD = 3.97 years), and children (Mage = 51 months; SD = 1.22 months) from the Panel Study on Korean Children. Results revealed that stressful family life events were positively associated with children's internalizing and externalizing behaviors but not via family functioning and parental warmth. Family functioning and mothers' warmth successively mediated the association between father involvement and children's internalizing and externalizing behaviors. Father involvement moderated the association between stressful family life events and children's externalizing behaviors. The findings highlight that father involvement may play a protective role in children's externalizing behaviors when Korean families experience stressful situations. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

A French-Language Web-Based Intervention Targeting Prolonged Grief Symptoms in People Who Are Bereaved and Separated: Randomized Controlled Trial.

Losing a loved one, through death or separation, counts among the most stressful life events and is detrimental to health and well-being. About 15% of people show clinically significant difficulties coping with such an event. Web-based interventions (WBIs) are effective for a variety of mental health disorders, including prolonged grief. However, no validated WBI is available in French for treating prolonged grief symptoms. This study aimed to compare the efficacy and adherence rates of 2 WBIs for prolonged grief symptoms following the loss of a loved one through death or romantic separation. LIVIA 2.0 was developed relying on theoretical and empirical findings on bereavement processes and WBIs, and is compared with LIVIA 1, which has already demonstrated its efficacy. We conducted a randomized controlled trial and provided on-demand guidance to participants. Outcomes were assessed through web-based questionnaires before the intervention, after the intervention (12 weeks later), and at follow-up (24 weeks later). Primary outcomes were grief symptoms, depressive symptoms, and well-being. Secondary outcomes were anxiety symptoms, grief coping strategies, aspects related to self-identity, and program satisfaction. In total, 62 participants were randomized (intent-to-treat [ITT] sample), 29 (47%) in LIVIA 2.0 (active arm) and 33 (53%) in LIVIA 1 (control arm). The dropout rate was 40% (37/62), and 10 participants were removed due to exclusion criteria, leading to a final per-protocol sample of 27 (44%) completers who differed from noncompleters only based on reporting fewer anxiety symptoms (t60=3.03; P=.004). Participants who are separated reported more grief symptoms (t60=2.22; P=.03) and attachment anxiety (t60=2.26; P=.03), compared to participants who are bereaved. There were pre-post within-group differences for both programs in the ITT sample, with significant reductions in grief (Cohen d=-0.90), depressive symptoms (Cohen d=-0.31), and centrality of the loss (Cohen d=-0.45). The same pattern was observed in the per-protocol sample, with the exception that anxiety symptoms also significantly diminished (Cohen d=-0.45). No difference was found in efficacy between the 2 programs (all P>.33). Participants (ITT sample) reported overall high levels of program satisfaction (mean 3.18, SD 0.54; over a maximum of 4). Effect stability was confirmed at the 6-month follow-up for all outcomes, with an improvement in self-concept clarity. The 2 grief-related WBIs were effective in reducing grief, depressive and anxiety symptoms for participants who are bereaved or separated. The analyses did not reveal any pre-post between-group differences, suggesting that the innovations brought to LIVIA 2.0 did not significantly affect the outcome. However, caution is warranted with the interpretation of the results given the limited power of the sample, which only allows the detection of medium effect sizes. ClinicalTrials.gov NCT05219760; https://clinicaltrials.gov/study/NCT05219760. RR2-10.2196/39026.

Association of psychosocial state with subsequent risk of dementia: a prospective cohort study based on the UK Biobank

BackgroundMultiple psychosocial factors have been associated with dementia, while the individual or joint effects of various psychosocial states on dementia remain unrevealed due to the complex interplay between those factors. Here, the authors examined the associations of psychosocial factors and patterns with subsequent risk of dementia, and if the associations could be modified by genetic susceptibility to dementia.MethodsUK Biobank dementia-free participants were followed from one year after recruitment (median date: 24 January, 2010) until 31 October, 2022. Psychosocial states were measured by 22 items related to five dimensions, including psychiatric history, recent stressful life events, current psychiatric symptoms, social contact, and individual socioeconomic state. We identified clusters of individuals with distinct psychosocial patterns using latent class analysis. Cox proportional hazards models were used to evaluate the association between psychosocial items, as well as psychosocial patterns, and risk of dementia. We further performed stratification analyses by apolipoprotein E (APOE) genotype, polygenic risk score (PRS) of dementia, and family history of dementia.ResultsOf 497,787 included participants, 54.54% were female. During a median follow-up of 12.70 years, we identified 9,858 (1.98%) patients with newly diagnosed dementia. We identified seven clusters with distinct psychosocial patterns. Compared to individuals with a pattern of ‘good state’, individuals with other unfavorable patterns, featured by varying degrees of poor psychological state (‘fair state’ and ‘mildly, moderately, and extremely poor psychological state’), low social contact or socioeconomic state (‘living alone’ and ‘short education years’), were all at an increased risk of dementia (hazard ratios [HR] between 1.29 and 2.63). The observed associations showed no significant differences across individuals with varying APOE genotypes, levels of PRS, and family histories of dementia.ConclusionUnfavorable psychosocial patterns are associated with an increased risk of dementia, independent of genetic susceptibility. The findings highlight the importance of surveillance and prevention of cognitive decline among individuals with suboptimal psychosocial state.

Aglycone Analysis and Quantitative Tracking of Correlated Terminal Glycan Pair on Spermatozoa.

Mammalian sperm glycans directly mediate several key life events. However, previous studies have not focused on two key factors that regulate these processes, the terminal glycan pattern and the anchoring sites. Herein, we group the capping monosaccharide sialic acid (Sia) and its capping substrates galactose/N-acetylgalactosamine (Gal/GalNAc) into a "correlated terminal glycan pair" (glycopair) and, for the first time, reveal the differences in the aglycone pattern of this pair on spermatozoa using glyco-selective in situ covalent labeling techniques. Sia is mainly found in glycoproteins, whereas terminal Gal/GalNAc is mainly found in glycolipids. We quantitatively track the dynamic changes of the glycopair during sperm epididymal migration and find that the Sia capping ratio decreases with the increased expression of the glycopair; caudal upswim spermatozoa also show a lower Sia capping ratio than down spermatozoa. We thus propose two new parameters reflecting the terminal glycoforms of spermatozoa, which can well distinguish the maturity of spermatozoa. By fluorescence imaging of the glycopair in different regions of the sperm, we find that different parts of the sperm contribute differently to the overall glycan changes.

Shape of the past: Revealing detail arcs while narrating memories of autobiographical life events across the lifespan.

Humans can remember past autobiographical events through extended narratives. How these narrated memories typically unfold, however, remains largely unexplored. We evaluated how autobiographical memory details typically come together in a sample of 235 healthy young, middle-aged, and older adults. We found that details providing background knowledge followed a U shape, such that they were most prevalent in the initial moments of remembering before falling and then rising near the conclusion of the memory's retelling. Details about the scene of the memory declined over time, whereas other event-specific, unique details about the main features of the event followed an inverted U shape, peaking around the midpoint of a remembered event's narration. Whereas most detail arcs were not significantly affected by older age, older adults showed a significant underuse of details describing the scene early in memory retrieval. Our findings suggest that behind the ability to narrate the remembered past is a normative waxing and waning of the details that make autobiographical memories.

Cognitive causes of the mental state of terror and their link to mental health outcomes.

The mental state of terror is a dysphoric emotion, feeling of dread and sudden realisation that the outcomes of one's life events can take an extremely negative turn. The state represents the acute stage of fear, anxiety and trauma and generally occurs in mental disorders, such as trauma- and stress-related disorders, but it can also manifest in healthy individuals as the initial trigger response, the point of mental dysregulation. The mental state of terror can be specified with the following parameters: (1) perceived loss of safety, (2) unpredictability and uncertainty, (3) intense consequent emotional reaction, (4) hypersensitivity to the trigger stimuli, and consequentially, (5) the outcome that can be either negative, such as resulting in developing a mental disorder, or positive, such as developing post-traumatic growth and resilience. Behavioural biases are also a for factor the development of the mental state of terror. The aim of this theoretical contribution is to define the mental state of terror in terms of cognitive factors, such as exposure to traumatic events and uncertainty of the environment for understanding the development of mental disorders within stress and trauma domains; highlight the importance of psychological resilience and social support.

Primary and secondary prevention of postpartum depression

Pregnancy is one of the important life events in a woman's life, which in the face of pregnancy, childbirth and breastfeeding process, maternal psychology and physiology will have obvious changes, among which postpartum depression is more common. Postpartum depression (PPD) is a mental syndrome with obvious depressive symptoms or typical depressive episodes during the puerperal period. Its etiology is complex, with sleepiness, gloomy expression, crying and other symptoms in clinic, and even some patients will have suicidal tendencies, which seriously endangers maternal physical and mental health. In recent years, the adverse events caused by postpartum depression have attracted more and more social attention, and postpartum women's mental health has become a hot spot in clinical research. Clinical workers should improve the awareness of postpartum depression, and strengthen the maternal mental health screening, so as to detect psychological abnormalities as early as possible and give timely intervention measures. In view of the high incidence of postpartum depression, it is very important to establish a sound mental health service system for pregnant women. This paper will analyze the high risk factors of PPD summarized the targeted primary prevention and secondary prevention, and proposed prevention strategies before and after the onset of postpartum depression, respectively, to provide theoretical basis for effectively preventing the occurrence of postpartum depression or delaying the progression of postpartum depression.