Event matching is a core in decoupled end-to-end communications, which are extensively applied to various areas. Event matching seeks the subscriptions that match a given event from a subscription set, however, this work becomes increasingly complicated in content-based multi-attribute scenarios, where events and subscriptions are formed in content, and described by multiple attributes. In addition, large-scale systems are easier to suffer from severe degradation in event matching performance. To this end, this paper presents a high-efficiency content-based multi-attribute event matching algorithm, called HEM (hybrid event matching), which is hybridized by 2 different methods. In HEM, the matching on each single attribute (called single-attribute matching) is processed by a triangle-based matching method or a direct matching method dynamically. All single-attribute matchings are sorted via a fast near-optimal algorithm, and each of them is carried out sequentially. In this manner, the searching space of event matching shrinks gradually, so that the searching performance is boosted along with the process of event matching. Experiments are conducted to evaluate HEM comprehensively, where it is observed that HEM outperforms 3 state-of-the-art counterparts (TAMA, H-TREE and REIN) in main criteria, such as event matching time, insertion time and deletion time. Moreover, the gap of performance between HEM and the counterparts enlarges with the increase of system scale.