Evaporative Stimuli Research Articles

Efficacy of Experimental Propolis‐Based Toothpastes on Dentin Hypersensitivity: A Randomized Clinical Trial

Background. Propolis is a natural bee product that has garnered attention due to its harmlessness and numerous beneficial biological properties. This randomized, double‐blinded, placebo‐controlled clinical trial aimed to assess the effect of toothpastes containing different concentrations of propolis (10% and 15%) on the control of dentin hypersensitivity (DH). Methods. From adults aged 18–40 years with DH, 66 teeth were randomly divided into 3 treatment groups as follows (n = 22): control (toothpaste without active ingredient), 10% propolis toothpaste, and 15% propolis toothpaste. DH was assessed thrice (baseline and 15 and 30 days after treatment) by tactile and evaporative stimuli using the visual analog scale. Data were analyzed using Friedman and Kruskal–Wallis tests. A significance level of 5% was used in all analyses. Results. All the groups showed a reduction in DH during the study (p < 0.05). The experimental groups (10% and 15% propolis) showed significantly greater reduction in DH than the control group (p < 0.05) after 30 days of treatment; however, the experimental groups displayed similar results (p > 0.05). Conclusion. Toothpastes containing propolis at concentrations of 10% and 15% were equally effective in controlling DH, regardless of their concentration. Trial Registration. This trial is registered with NCT05083052. Date of registration: 19/10/2021.

COMPARATIVE EVALUATION OF EFFICACY AND DURABILITY OF SELF-CURE AND LIGHT-CURE DESENSITIZING AGENTS IN THE TREATMENT OF DENTIN HYPERSENSITIVITY- AN IN-VIVO STUDY

Objectives:This in vivo study aimed to compare the efficacy and durability of three different varnishes/Desensitizing agents. Fluoride varnish, self-cure varnish, and light-cure varnish were used to treat dentin hypersensitivity by blocking dentinal tubules. Materials and Methods: A total of 60 patients were randomly assigned into three groups Group A: received desensitizing fluoride varnish (ProfluoridVarnish, Voco), Group B: received self-cure varnish (Systemp desensitizer, IvoclarVivadent) and Group C: received light-cure varnish (Admira Protect, Voco). Assessment of air and tactile sensitivity was done based on visual analogue scale scores at baseline, immediately after treatment, and one-monthpost-treatment. One-way ANOVA was used to assess the level of significance. Results:The results showed there was no statistically significant difference in the VAS scores for tactile and evaporative stimuli between the three groups immediately after treatment. Group C – Admira Protect showed lesser mean VAS scores for both the stimuli immediately and after 30 days of application which was statistically significant with post hoc correction. Conclusion:Allthree varnishes were effective in treating DH immediately after a single application. Profluorid Varnish showed lessefficacy when compared to resin varnishes at the end of one month. Clinical effectiveness was less at the end of one month for Systemp desensitizer, a self-cure varnish when compared to Admira Protect a light cure varnish.

Clinical Efficacy of Mouthwashes with Potassium Salts in the Treatment of Dentinal Hypersensitivity: A Systematic Review and Meta-analysis.

This systematic review and meta-analysis evaluated whether the home use of mouthwashes containing potassium salts is effective in reducing and controlling dentin hypersensitivity (DH). This study is reported according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) checklist and was registered in PROSPERO (CRD42021228410). Randomized clinical trials evaluating the use of mouthwashes containing potassium salt for daily household mouthwash for at least four weeks to reduce DH compared with a control mouthwash were selected, with no limitation on year of publication. Electronic research was carried out in PubMed/MEDLINE, Scopus, Web of Science, and Cochrane Library by two independent researchers. One hundred thirty-three articles were obtained, and nine were selected according to the inclusion criteria. The selected studies evaluated DH through tests of sensitivity to tactile and evaporative stimuli and showed that, for the tactile stimulus, there were no baseline differences between groups (p=0.12; mean difference: -0.33; confidence intervals [CI]: -0.73 to 0.08). However, there were significant differences after two weeks of use (p=0.00001; mean difference: 4.67; CI: 4.53 to 4.81), after four weeks (p=0.00001; mean difference: 13.29; CI: 13.03 to 13.55), and after eight weeks (p=0.00001; mean difference: 8.88; CI: 5.73 to 12.02) favoring the experimental group. The results of the evaporative test showed no differences in the baseline assessment between the two groups (p=0.50; mean difference: -0.02; CI: -0.09 to 0.04), but after four weeks (p=0.00001; mean difference: -0.32; CI: -0.44 to -0.20), and eight weeks of use (p=0.00001; mean difference: -0.42; CI: -0.57 to -0.27) there were differences favoring the experimental group. The incidence of side effects showed no differences between the two groups (p=0.89; mean difference: 1.03; CI: 0.67 to 1.58). The daily use of mouthwashes containing potassium salt is effective in the treatment of dentinal hypersensitivity, as a complementary step to brushing at least twice a day for two weeks, four weeks, and up to eight weeks, without presenting side effects.

Can non-carious cervical lesions depth affect clinical response in pain intensity and remaining dentin thickness?

Non-carious Cervical Lesions (NCCL) are dental tissue defects, non-related to caries, frequently observed in the dental practice. The aim of this study was to evaluate the effects of NCCL on dentin depth and thickness and the response to dental pain by means of clinical diagnostic tests. 86 teeth from 14 patients with NCCL were assessed by: depth of NCCL, clinical tests (evaporative stimulus, to detect pain levels of dentin hypersensitivity, cold thermal test to classify pulp health, percussive stimuli to evaluate the periradicular tissues and cone beam computed tomography (tomography to evaluate remaining dentin thickness (RDT). In terms of depth, the sample was divided into two groups: G1- teeth with NCCLs ≤1.0mm and G2- teeth with NCCLs between 1.1-2.0 mm. Dental pain data were compared by Mann-Whitney test and RDT by Student's t-test and correlations by the Pearson test (p<0.05). The depth of NCCL does not influence dental pain response to evaporative stimulus (p=0.129), cold thermal test (p = 0.125), vertical (p = 0.317) and horizontal (p = 0.119) percussion clinical diagnostic tests. However, G1 showed more RDT (p<0.001), and the correlation test showed that deeper NCCL presents smaller remaining dentin thickness (p=0.011/r=-0.273). In conclusion, tooth with NCCL up to 2mm-depth presents similar levels of pain for dentin hypersensitivity, pulp and periradicular tissue independent to NCCL depth, however, lesions with ≤1.0mm-depth showed greater RDT in tomographic findings.

Successful management of dentin hypersensitivity: A narrative review.

The prevalence of dentin hypersensitivity (DH) is increasing around the world. At least one in 10 individuals in the general population has been diagnosed with DH. It is a diagnosis that has significant negative effects on a person's oral health-related quality of life. This condition, which is characterized by sharp, short tooth pain in response to thermal, chemical, tactile, and evaporative stimuli, is more commonly seen in adults. DH has a tremendous impact on the social and financial aspects of patients and society at large. It is essential to recognize the factors that can contribute to a successful treatment outcome to guarantee the overall well-being of DH patients. The aim of this narrative review was to highlight strategies that can lead to successful DH treatment outcomes, along with current updates on DH mechanisms, treatment options, and the latest management approaches. A positive treatment outcome for DH requires a concerted effort from both the patient and the dental practitioner. Highly motivated patients and dental practitioners with sound knowledge of DH diagnosis and available treatment options will ensure successful long-term improvement of DH symptoms.

Dentin hypersensitivity treatment with ozonated oil: a randomized controlled triple-blind clinical trial

The present study aimed to assess dentin hypersensitivity (DH) level and quality of life in patients before and after treatment with ozonated oil compared with extra virgin oil. This is a randomized triple-blind controlled clinical trial, consisting of patients with dentin hypersensitivity which was stimulated by evaporative and thermal stimuli. DH level was measured using a numerical rating scale. The patients were treated with ozonated oil and olive oil. Data were measured at baseline, immediately, and 4 weeks after treatment. The Dentine Hypersensitivity Experience Questionnaire (DHEQ-15) and the Oral Health Impact Profile (OHIP-14) were applied at baseline and 4 weeks after treatment. The sample consisted of 8 women and 3 men, with an average age of 23.82 years. The test group was 40 teeth while the control group consisted of 36 teeth, with the most prevalent tooth being the incisor (52.6%). There was a significant reduction in the DH level and an improvement in the quality of life after treatment. Among the sample, 90.1% reported an improvement in the final result. Both ozonated oil and olive oil were effective in reducing dentin hypersensitivity level and improving oral health-related quality of life 30 days after treatment.

Comparison between effectiveness of dentine desensitizer and one bottle self-etch adhesive on dentine hypersensitivity.

Dentine hypersensitivity is one of the most common chief complaints of patients observed by dentists in their practice. However, there is a lack of universal consensus over the selection of reliable treatment modality. To compare the effectiveness between dentine desensitizer and self-etch adhesive in patients complaining of moderate to severe dentine hypersensitivity pain. A total of 254 patients with moderate to severe dentine hypersensitivity were randomly divided into Group A (Single Bond Universal Agent) and Group B (Seal & Protect Agent) according to the treatment provided. Sensitivity was assessed by means of mechanical (probing) and evaporative (air blast) stimuli. Discomfort Internal Scale (DIS) was explained to patients. DIS scores were recorded after one minute and one month following the application of both agents. Descriptive statistics were calculated. Stratification was done to control confounder and post stratification chi-square test was also applied. The statistically significant difference (p= 0.000) in effectiveness between the two groups was observed. The mean discomfort internal scale score at baseline, after 1minute and after 1month in Group A was 3.65 ± 0.60, 2.33 ± 0.64 and 0.41 ± 0.71 respectively, while in Group B, it was 3.55 ± 0.58, 2.40 ± 0.62 and 0.72 ± 0.92 respectively. Overall, 86.6% patients observed improvement in dentinal sensitivity in Group A while in Group B only 67.7% patients reported reduction in sensitivity. Self-etch adhesive significantly reduces dentin hypersensitivity, immediately after one minute of its application and is effective for a period of one month compared to desensitizing agent.

COMPARATIVE EVALUATION OF EFFECTIVENESS OF CASEIN PHOSPHOPEPTIDE AMORPHOROUS CALCIUM PHOSPHATE AND SODIUM FLOURIDE VARNISH IN DENTINE HYPERSENTIVITY

Objective: To determine efficacy of casein phosphopeptide amorphous calcium phosphate and sodium fluoride varnish in managing dentine hypersentivity.&#x0D; Study Design: Quasi-experimental study.&#x0D; Place and Duration of Study: Foundation University College of Dentistry, Islamabad, from Jun to Nov 2020.&#x0D; Methodology: Patients of both gender 20-60 years of age with ASA “American Society of Anesthesiologists physical status classification” status I (completely healthy fit patient) or status II (patient has mild systemic disease) diagnosed with dentine hypersensitivity of incisors, canines, premolars with clinical evidence of erosion, abrasion, gingival recession not requiring restorative treatment were enrolled in the study. At first visit baseline, dentine hypersentivity was recorded by means of tactile and evaporative stimuli, response was quantified using visual analogue scale. Patients were randomly divided in two groups 1-casein phosphopeptide amorphous calcium phosphate, 2-sodium fluoride varnish desensitizing agent was applied conferring to manufacturer instructions. Visual analogue scale readings were assessed at base line and post treatment valueswas recorded at 7th, 15th, 30th day.&#x0D; Results: Total 80 patients enrolled in the study with a mean age of 36.26 ± 8.91 years and age-range of 21-60 years. Visual analogue scale results of group-1 (n=40) were recorded at baseline as 5.9 ± 0 .94, 7th day 1.9 ± 0.92, 15th day 1.4 ± 0 .81 and 30th day 1.0 ± 0.71. In case of group-2 Visual Analogue Score recorded to be 6.2 ± 1.24,3.2 ± 0.81, 3.0 ± 0.52 and 2.7 ± 1.12 at baseline, 7th, 15th, and 30th day respectively.&#x0D; Conclusion: Casein phosphopeptide amorphous..................

Hypersensitivity relief of MIH-affected molars using two sealing techniques: a 12-week follow-up

ObjectivesThe aim of this study was to compare the efficacy in reducing hypersensitivity in molar incisor hypomineralization (MIH)-affected molars immediately and over 12 weeks after sealing using two different materials (composite and glass ionomer). Furthermore, the retention rates of both materials were analyzed.MethodsThirty-nine children with two MIH-affected molars showing hypersensitivity and non-occlusal breakdowns were included. Hypersensitivity was assessed with an evaporative (air) stimulus. Both teeth were sealed by two calibrated operators using a split-mouth design with either Clinpro Sealant in combination with Scotchbond Universal (C) or Ketac Universal (K), respectively. Clinical pain assessments (Schiff Score Air Sensitivity Scale [SCASS], Visual Analog Scale [VAS]) were made at baseline (“pre”), immediately after treatment (“post”), and after 1, 4, 8, and 12 weeks. Paired t tests were calculated in each group between baseline and all other time points.ResultsThirty-eight children with 76 molars completed all stages of the study. Regardless of the material used, the application of the sealant decreased hypersensitivity significantly immediately as well as throughout the 12-week recalls (all p values < 0.001). We found no statistically significant difference among both materials chosen in any of the time points evaluated. Furthermore, retention of both materials was comparable in both groups.ConclusionsBoth sealant materials were able to reduce hypersensitivity successfully immediately and throughout the 12-week follow-up. Furthermore, their performance was similar in terms of retention.Clinical relevanceHypersensitivity can be a major complaint in patients with MIH. This is the first study evaluating hypersensitivity relief of MIH-affected molars using two sealing techniques.

Evaluation and comparision of the clinical effectiveness of diode laser and Gluma as desensitizing agents in the treatment of dentinal hypersensitivity

Dentin hypersensitivity is one of the most common presenting symptoms in dental practice. It may range from mild discomfort to severe pain affecting the person. Laser desensitization has been introduced as a useful tool for the treatment of hypersensitivity. Gluma Dentin Bond is an adhesive system, where the primer contains 5% glutaraldehyde and 35% hydroxyethyl methacrylate. Practitioners have reported a strong desensitizing effect of the Gluma® system on dentin The aim of this study is to evaluate and compare the clinical effectiveness of Diode laser and Gluma ®desensitizing agent in the treatment of dentin hypersensitivity. 24 patients aged between 20 and 50 years was included to assess tooth sensitivity, a controlled air stimulus (evaporative stimulus) was used. Sensitivity was measured using a 10-cm Visual Aanalog Scale (VAS) score. The teeth was randomly allocated to two groups i.e., Group I or II using the lottery method. Gluma® showed a statistically significant reduction in the VAS score as compared to diode laser 1, 2- and 4-weeks follow-up period (p &amp;#60; 0.05). The result of the present investigation revealed that application of Gluma® resulted in better control dentin hypersensitivity as compared to diode laser.

Changes in oral health-related quality of life after treatment of hypersensitive molar incisor hypomineralization\u2013affected molars with a sealing

ObjectivesThe aim of this study was to investigate the changes in oral health-related quality of life (OHRQoL) before and after treatment of hypersensitive molars affected by molar incisor hypomineralization (MIH) with a sealing.MethodsThirty-eight children with two MIH-affected molars showing hypersensitivity and non-occlusal breakdowns were included. Hypersensitivity was assessed with an evaporative (air) stimulus. Two affected teeth were sealed by two calibrated operators using a split-mouth design: Clinpro Sealant in combination with Scotchbond Universal, and Ketac Universal (3M), respectively. OHRQoL was measured using the German version of the CPQ8–10 (CPQ-G8–10) at baseline, and after 1, 4, 8, and 12 weeks, respectively.ResultsThe CPQ total score decreased significantly from a mean of 14.7 (±5.9) to 6.4 (±4.7) (p < 0.001) 1 week after treatment revealing improved OHRQoL. After 12 weeks, OHRQoL improved again proven by a decreased mean score of 2.7 (±3.2).ConclusionsSealing of hypersensitive MIH-affected molars revealed a significant improvement of OHRQoL immediately and throughout the 12-week follow-up.Clinical relevanceHypersensitivity can be a major complaint in patients with MIH. This is the first study evaluating the effect of sealing on OHRQoL in affected patients.

Comparação da eficácia do fluoreto de sódio a 4% e do LASER de baixa potência no tratamento da hipersensibilidade dentinária cervical

Objetivo: Avaliar a eficácia do uso da solução de fluoreto de sódio a 4% para o tratamento da Hipersensibilidade Dentinária Cervical (HSDC) em comparação ao LASER de baixa potência. Método: Foi realizado um ensaio clínico controlado randomizado, constituído por um grupo teste (47 dentes) e grupo controle (47 dentes). Para o grupo teste foi realizada aplicação do fluoreto de sódio a 4%, e o grupo controle recebeu irradiação do LASER de baixa potência. As terapias dos dois grupos foram realizadas em três sessões com intervalo de uma semana entre elas. Previamente ao tratamento (T0), imediatamente após a aplicação das terapias em cada sessão (T1, T2 e T3), e nos tempos de 1 (T4), 3 (T5) e 6 (T6) meses, os elementos dentários foram submetidos aos estímulos táctil e térmico-evaporativo e as respostas foram obtidas através da Escala Visual Numérica (EVN). A análise estatística dos dados foi realizada através dos testes não paramétricos Wilcoxon, Friedman e Mann-Whitney. Resultados: Em T6, a média de dor do grupo teste passou de 5,93 para 1,73 (p &lt; 0,05) ao estímulo evaporativo e de 3,63 para 0,804 ao estímulo táctil (p &lt; 0,05). Para o grupo controle, a média da dor passou de 6,020 para 1,854 (p &lt; 0,05) ao estímulo evaporativo e de 3,50 para 0,937 (p &lt; 0,05) ao estímulo táctil. Não houve diferença entre as duas modalidades de tratamento em T6. Conclusão: O fluoreto de sódio a 4% foi tão eficaz quanto o LASER na redução da HSDC.

Photobiomodulation vs. Placebo on Post-Bleaching Sensitivity and Color Change: A Split-Mouth Clinical Study

Objective: This study aimed to investigate the efficiency of Photobiomodulation (PBM) with low-level LASER therapy compared to placebo in post-bleaching sensitivity and color change during a three-week office bleaching treatment. Methods: A split-mouth model was used to evaluate 21 subjects. The right and left hemi-archs were randomized to one of two groups: GP (placebo): simulated LASER application followed by tooth bleaching with 35% hydrogen peroxide; and GL: treated with PBM followed by tooth bleaching with 35% hydrogen peroxide. A four-degree modified Visual Analog Scale (VAS) was used to assess tooth sensitivity after the application of an evaporative stimulus (stimulated pain). In addition, a daily questionnaire was used to measure unstimulated pain. The color change was measured using a spectrophotometer. The Friedman and Wilcoxon tests were used to analyze data sensitivity. Color results were statistically analyzed using Analysis Of Variance (ANOVA) followed by the Tukey post-hoc test. Results: There was no significant difference between GP and GL for stimulated pain evaluation (p&gt; 0.05). However, there was a significant difference between the groups for unstimulated pain evaluation (p≤ 0.05). In addition, ΔE data did not reveal any significant difference in tooth color between groups at any time (p&gt; 0.05). Conclusion: PBM prevented post-bleaching sensitivity compared to placebo, based on the daily pain assessment questionnaires. PBM did not compromise the quality of bleaching treatments.

Low-power laser and potassium oxalate gel in the treatment of cervical dentin hypersensitivity-a randomized clinical trial.

To evaluate the effectiveness of different protocols for the treatment of cervical dentin hypersensitivity (CDH) in non-carious cervical lesions (NCCLs). The CONSORT checklist was used to design this study. The sample with n = 74 participants (389 NCCLs) was randomly allocated into three groups: G1, potassium oxalate (Oxa-Gel BF); G2, GaAlAs (gallium-aluminum-arsenate) low-power laser (100mW, 808nn, 60J/cm2); and G3, potassium oxalate (Oxa-Gel BF) associated with the GaAlAs low-power laser. The CDH was triggered by the evaporative stimulus test (EST) and by the tactile stimulus test (TST). The visual analog scale (VAS) was used to quantify the degree of CDH. Changes in sensitivity were assessed from baseline over 3weeks. Data were analyzed for NCCLs using mixed-effects models with unstructured direct product covariance structure (α = 0.05). After the first application, participants from G1 and G3 had a reduction in CDH (p < 0.05) compared with group G2 for TST. After the second application, G3 participants had a reduction in CDH (p < 0.05) in relation to G2 for both stimuli. Reduction in CDH (p < 0.05) occurred over 3weeks for EST and TST for all groups; however, there was no difference between groups at the end of the therapies. Potassium oxalate was more effective in reducing immediate CDH. After four applications, all groups showed similar results for the reduction of CDH. GaAlAS laser irradiation and oxalate potassium gel could reduce the symptoms of CDH; thus, they are viable alternatives for the treatment of this condition. Chemical occlusion of dental tubules showed effective results after a shorter time interval. Brazilian Clinical Trials Registration Platform under protocol number RBR-4ybjmt. http://www.braziliantrials.com/?keywords=RBR-4ybjmt&order=%7Eensaios.patrocinador_primario.

Sylc Air Polishing Versus Fluoride Varnish Application in Managing Dentin Hypersensitivity in Non-Carious Cervical Lesions: A Randomized Clinical Trial

Objective: To determine the effectiveness of Sylc (a bioactive glass-based powder) delivered by an air polishing system compared to fluoride varnish application in managing Dentin Hypersensitivity (DH). Methods: This study was a double-blinded randomized clinical trial where 50 participants with DH in at least one tooth with a non-carious cervical lesion were included and randomized into two groups (25 participants each) to receive either Sylc air polishing or fluoride varnish application. Baseline and post-intervention measurements of pain were carried out using evaporative, thermal and tactile stimuli using a modified visual analog scale at 3 minutes, 1, 2, 3and 4 weeks, 6 months and 1 year post-intervention. Data for pain intensity was recorded and analyzed for each group. Results: For the three stimuli used, Sylc air polishing showed statistically significant reduction of pain intensity (P&lt;0.05) after 3 weeks and up to 1 year post-intervention. Fluoride varnish application showed a statistically significant reduction of pain intensity in evaporative and thermal stimuli at 1 week post-intervention only. Conclusion: Sylc air polishing was effective in relieving pain due to DH after 3 weeks and up to 1 year post-intervention, which showed that it can be used as a long-term treatment for DH.

A comparative evaluation of propolis and light-cured ormocer-based desensitizer in reducing dentin hypersensitivity.

Objectives:The purpose of the study was to evaluate and compare the clinical efficacy and the durability of propolis and Light-cured ormocer-based desensitizer (Admira Protect, Voco: Cuxhaven Germany) in the treatment of dentin hypersensitivity (DH).Materials and Methods:The study was conducted over a period of 2 months on 13 patients with 72 hypersensitive teeth, randomly allocated into three treatment groups: Group A: Treated with Propolis, Group B: Admira protect (Voco: Cuxhaven Germany), and Group C: Sterile water (Placebo control). Baseline sensitivity was recorded by the operator using tactile and evaporative stimuli. Visual analog scale (VAS) was used to record the degree of sensitivity perceived by the patients. All the groups received applications of allotted materials on day 1, 7, 14, and 21. After each applications VAS scoring was recorded. On day 30 and 60, only pain evaluation was done to determine the durability of each test materials.Statistical Analysis:One-way ANOVA, repeated measure ANOVA and post hoc test was done for multiple comparison.Results:All the groups showed significant results in reducing DH. Among Groups A and B, Group B showed immediate postoperative result at the end of the 1st week.Conclusion:Both the test materials were effective in reducing DH but Admira protect was found to be more efficient in reducing pain with longer duration of action (CTRI regd no: CTRI/2017/12/010755).

Effectiveness of diode laser and fluoride on dentin hypersensitivity treatment: A randomized single-blinded clinical trial.

Background:This randomized single-blinded clinical trial aimed to evaluate the effectiveness of diode laser and fluoride in the treatment of dentin hypersensitivity (DH) due to gingival recession.Materials and Methods:Twenty-eight individuals randomly distributed across three groups participated: 10 individuals who were treated with diode laser, nine who were treated with fluoride, and nine who received placebo. Pain was assessed with the Visual analog scale (VAS). Evaporative stimulus and tactile stimulus were evaluated with the verbal rating scale (VRS). VAS was applied shortly after, 6 h after, 12 h after, and 24 h after the single-session treatment for DH, whereas VRS was applied shortly after, 15 min and 7 days after the treatment. Participants' quality of life was assessed with the validated Brazilian version of the Dentine Hypersensitivity Experience Questionnaire assessing functional limitations, coping behaviors, emotional, and social impacts caused by DH. Descriptive statistics and the ANOVA test were used. Values of P < 0.05 were statistically significant.Results:Diode laser significantly reduced the DH to the evaporative stimulus (P = 0.002). The application of fluoride did not change the degree of DH to evaporative and tactile stimuli (P > 0.05). The group of individuals who were treated with diode laser presented a higher reduction in DH (25.4%) when compared to the group of individuals treated with fluoride (17.1%), and the group of individuals among whom placebo had been used (2.9%). Descriptive analysis indicated that the items measuring the emotional and social impacts of DH were those with a more negative impact on the individuals.Conclusion:Therapy with diode laser was more effective in reducing DH than therapy with fluoride.

Effect of the casein phosphopeptide-amorphous calcium phosphate fluoride (CPP-ACPF) and photobiomodulation (PBM) on dental hypersensitivity: A randomized controlled clinical trial.

ObjectiveThis randomized controlled clinical trial aimed to evaluate the effect of the casein phosphopeptide-amorphous calcium phosphate fluoride (CPP-ACPF) and photobiomodulation (PBM) in the treatment of dentin hypersensitivity (DH), and the impact of this on the health-related quality of life (HRQL).MethodsEighty teeth with DH were randomized into four groups and received three treatment sessions: PLACEBO = placebo + LASER application mimicking; CPP-ACPF = CPP-ACPF + LASER application mimicking; PBM = placebo + LASER active application; CPP-ACPF+PBM = CPP-ACPF + LASER active application. Tactile (exploratory probe) and evaporative (triple syringe) stimuli were used to measure DH and were recorded with the aid of a visual analogue scale (VAS) after the 1st, 2nd and 3rd treatment sessions and one-month follow-up. The HRQL was recorded in the DH experience questionnaire (DHEQ).ResultsThe intragroup comparison showed a significant reduction in DH (p < 0.05) with both stimuli after one-month follow-up. The intergroup comparison with the evaporative stimulus showed that CPP-ACPF+PBM significantly reduced DH when compared to the rest of treatments, after one-month follow-up. CPP-ACPF+PBM group statistically differed from the other treatment groups in the DHEQ evaluation after one-month follow-up.ConclusionAfter one-month follow-up, the association of CPP-ACPF with PBM was effective in the reduction of DH and promoted a positive impact on the HRQL of the participants of this study.

Impact of toothpaste on oral health-related quality of life in people with dentine hypersensitivity

BackgroundDentine hypersensitivity can impact functional status and everyday activities such as eating and talking. This study aimed to assess changes in oral health-related quality of life measures in individuals with dentine hypersensitivity following long-term use (24 weeks) of a commercially available toothpaste marketed for dentine hypersensitivity relief.MethodsThis study was conducted across two sites and enrolled 75 adults with ≥2 non-adjacent sensitive teeth. Participants were assigned to twice-daily brushing with toothpaste containing 0.454% w/w stannous fluoride (1100 ppm fluoride). Every 4 weeks, participant-reported outcomes were assessed using the Dentine Hypersensitivity Experience Questionnaire (DHEQ), a condition specific oral health-related quality of life scale that has five domains and includes questions on social and emotional impact, restrictions, adaptations and effect on life overall. Responses to a clinically applied evaporative (air) stimulus were assessed using the examiner-observed Schiff sensitivity scale and Labelled Magnitude Scales (LMS), which included dentine hypersensitivity-specific descriptors of intensity, duration, tolerability and descriptive qualities of the participant’s response.ResultsParticipant-reported outcomes demonstrated reduction of the impact of dentine hypersensitivity over time on health-related quality of life, as measured by the DHEQ. This reached statistical significance from Week 8 onwards (p < 0.0001 versus baseline) for the Total DHEQ score, with scores continually decreasing at each timepoint. Most domain scores followed a similar pattern. Statistically significant reductions were also detected for the examiner-observed Schiff Sensitivity Scale scores at all timepoints (including at 4 weeks) (p < 0.05), which were mirrored by LMS responses. The toothpaste was generally well-tolerated.ConclusionsThese results show that long-term use of a sensitivity toothpaste containing 0.454% w/w stannous fluoride has a beneficial, ongoing, impact on the oral health-related quality of life of people with dentine hypersensitivity.Trial registrationThis study was registered at Clinicaltrials.gov (https://clinicaltrials.gov/ct2/show/NCT02752958) on April 27, 2016.

A randomised clinical trial on the efficacy of 5% fluorocalcium phosphosilicate-containing novel bioactive glass toothpaste.

Dentine hypersensitivity (DH) is a common and harrowing dental condition. A novel BioMin-F technology that contains 5% fluorocalcium phosphosilicate bioactive glass has been introduced. It forms fluorapatite, which is more stable towards acid erosion. There is a lack of literature with the utility of this toothpaste in treating DH. Therefore, the authors of this randomised clinical trial have aimed to compare and evaluate the efficacy of 5% fluorocalcium phosphosilicate with an 8% arginine and calcium carbonate and placebo toothpaste. A total of 75 patients clinically diagnosed with DH were randomly divided into three groups: Group A, 5% fluorocalcium phosphosilicate; Group B, 8% arginine and calcium carbonate; and Group C, placebo. The DH was evaluated by tactile and evaporative stimuli, and a visual analogue scale (VAS) was used for evaporative stimuli at pre-baseline, baseline (15days) and post-baseline (1month). The results showed symptoms of DH were reduced in all three groups. However, Group A showed a better reduction of DH than the other two groups. The toothpaste containing 5% fluorocalcium phosphosilicate was reported to be more efficacious than the other two toothpastes in managing DH. This novel development opens up a unique opportunity in the prevention and management of DH and may also be beneficial in preventing acid erosion of the tooth surface and in the maintenance of oral hygiene by reducing the effects of plaque accumulation and gingival inflammation.