Using prevalence data of white men in Evans County, Ga, this paper studies the relationship between coronary heart disease (CHD) and social mobility. Two basic findings are (1) that in both types of mobility, intragenerational and intergenerational, persons in the two lower social classes are more at risk if upwardly mobile than the stable populations; and (2) that upwardly mobile persons among the upper social classes show lower rates than the stable, a reversal of the other finding.