Evaluation Of Bilirubin Research Articles

Evaluation of Bilirubin, Phosphorus, Calcium and Cholesterol Levels in Bile of Livers Consistent with Hepatic Fascioliasis

Evaluation of Bilirubin, Phosphorus, Calcium and Cholesterol Levels in Bile of Livers Consistent with Hepatic Fascioliasis

Quality Control Monitoring & Evaluation of Bilirubin, Alkaline Phosphates and Inter-Laboratory Assessment of two Hospitals in North Central Nigeria

Quality Control Monitoring & Evaluation of Bilirubin, Alkaline Phosphates and Inter-Laboratory Assessment of two Hospitals in North Central Nigeria

Ischemia-modified albumin must be evaluated as an oxidative stress marker together with albumin and bilirubin in individuals with acute appendicitis

Ischemia-modified albumin must be evaluated as an oxidative stress marker together with albumin and bilirubin in individuals with acute appendicitis

Evaluation of bilirubin in a liver screening panel

Evaluation of bilirubin in a liver screening panel

Evaluation of Bilirubin in a Liver Screening Panel

To the Editor. —Since 1984, the clinical laboratory at the medical center of the University of California, San Francisco, has offered a three-test panel (bilirubin, alkaline phosphatase, and aspartate aminotransferase) for screening for liver disease. A clinician could order all three tests by selecting the panel option on the clinical laboratory order form. We recently investigated the contribution of bilirubin to this panel. We used the Combined Patient Experience database (University of California, San Francisco, Department of Laboratory Medicine), which was created by linkage of computerized data from three sources: the clinical laboratory, hospital information, and medical records. The database contains diagnostic, demographic, and laboratory test information for all inpatients during the study 1986 and 1987. Forty percent (12 459/31 064) of the adults aged ≥19 years during these 2 years had all three tests performed within 48 hours of admission. These 12 459 admissions constituted our study

Evaluation of bilirubin as possible protective factor in the prevention of retinopathy of prematurity.

Retinopathy of prematurity (ROP) appears to be a multifactorial disease, the prevention of which is probably impossible even with the most accurate methods of blood-gas monitoring and oxygen restrictions. The oxidative processes and consequent formation of free radicals are probably influenced by the availability of various antioxidants in the immature retina. Bilirubin, the end product of haem catabolism, has recently been regarded as a potential physiological antioxidant. In order to test the suggestion as to the possible effect of bilirubin in reducing the incidence of ROP a retrospective study was undertaken of the medical records of 151 neonates born between 1984 to 1988 who weighed less than 1500 g. Of these, 78 had various degrees of ROP, whereas 73 had no ROP and served as a control group. The daily mean bilirubin values were analysed in accordance with gestational age and birth weight as well as the severity of ROP, and the results were compared with those obtained for the control group. The results showed no correlation between bilirubin levels and severity of ROP in all subgroups of gestational age and birth weight. These findings indicate that there is no apparent protective effect of bilirubin on the development of ROP.

Evaluation of bilirubin in the newborn nursery

The clinical trials were completed in a community hospital nursery by nursing personnel. All 35 nurses involved in the experiment were instructed in the use of the bilirubinometer according to the instruction manual. Laboratory comparisons were performed in the hospital laboratory by one technician receiving the same training instructions. Standard bilirubin solutions were prepared 5 by dispersing 20 mg of commercial crystalline bilirubin in 1.0 ml of dimethylsulfone followed by the addition of 2.0 ml of 0.1M Na2CO~. A clear solution was obtained to which was added 95 ml of pooled cord serum. The pH was adjusted to 7.3 to 7.4 by adding approximately 2 ml of 0.1 M HC1. The solution was diluted to final concentration with cord serum (5, 10, 15, and 20 mg/dl) under subdued light. Solutions were stored at --20~ each of two stock solutions four samples were prepared at these concentrations. No less than 15 determinations were made on each sample. Pediatric versatol was reconstituted with distilled water and then diluted to final concentrations by several laboratory personnel. Specimens were refrigerated at approximately 4~ and were used within 72 hours of reconstitution.

Method for Simultaneous Direct Estimation of Glucose and Xylose in Serum

Abstract A direct procedure for measuring serum monosaccharides is presented. Borate intensifies the colors produced when these substances react with o-toluidine, which, in the case of glucose and xylose, have absorption maxima at 480 nm and 630 nm, respectively. Thus, these sugars may be determined singly or simultaneously in a single sample by differential spectrophotometry. An alternative technique in which glucose oxidase and o-toluidine are used is also presented for the estimation of xylose and other pentose sugars in the presence of glucose. These two techniques permit the measurement of a pentose and a hexose other than glucose in protein solutions containing glucose. The techniques have a high degree of correlation and reproducibility. The effects of such variables as reagent concentration, reaction time, and borate concentration on the o-toluidine reaction are presented, along with an evaluation of bilirubin and hemoglobin interference.