Objective To analyze healthcare quality assessment in prisons through a systematic review of the available scientific evidence. Material and method A literature search was performed in Medline, Excerpta Medica, Índice Médico Español, the Cochrane Library, and the official web pages of prison administrations in various countries. Data on the organizational model of healthcare in prisons in different countries, the methods used in quality assessment and results were gathered. Results There is little documentation on the subject, and it is not widely disseminated. Models of healthcare organization differ both among different countries and within the same country. There is no common model for evaluating healthcare quality in prisons. The most highly developed system is used in the prison administration of England and Wales. No article describing the whole evaluation process in prisons, including analysis of opportunities for improvement to evaluation of the results of the solutions proposed, was found. Conclusions Few documents were found on healthcare quality in prisons. Various models of healthcare organization are used in the correctional setting. There is no common methodology to assess healthcare quality and results. Tools for needs’ detection should be a priority as part of a broader model aimed at improving healthcare quality in prisons.