European Societies Of Toxicology Research Articles

Scientific toxicology societies in Europe

With the development of toxicology as a science, the second half of the 20th century saw the establishment of scientific societies, such as the International Society of Ecotoxicology and Environmental Safety (SECOTOX), the Federation of European Toxicologists and European Societies of Toxicology (EUROTOX), the Polish Society of Toxicology, and the European Society of Toxicologic Pathology (ESTP). This study describes their development, organizational structure and mission. The scope of their interest, in addition to toxicology, also includes ecotoxicology, which protects the natural environment and public health..

In vitro and in vivo genotoxicity of nano aluminum, aluminum oxide and aluminum chloride: A comparative study

Volume 280, Supplement 1, Pages S1-S346 (20 October 2017) Abstracts of the 53rd Congress of the European Societies of Toxicology (EUROTOX)Bratislava, Slovakia, 10th–13th September, 2017 Edited by Mumtaz Iscan and Helena Kandarova P-03-02-16 Aluminum on different forms is found in several goods: food addi- tives, medication, beverage, water treatment as well as cooking utensils. EFSA has established a tolerable weekly intake (TWI) of 1 mg/kg bw for human oral exposure (EFSA, 2008). Since the 2000s, due to the increasing use of nanoparticles (NP), aluminum NPs are expected to be more largely involved in human exposure although their effects on human health has not been fully characterized. Nevertheless, aluminum was depicted to cross epithelial barriers and to include neurotoxicity and embryotoxic- ity. As aluminum NPs may not behave as Al ions, their toxic effects must be investigated. In this study, we investigated the genotoxicity of Al, Al 2 O 3 NPs and the ionic form AlCl 3 on intestine, the contact organ fol- lowing oral exposure, and on liver, the main target organ for Al accumulation using both the alkaline comet assay and the Fpg- modified comet assay for highlighting potential oxidative damage. We observed DNA damage on the human intestinal Caco2 and hepatic HepaRG cells (exposure from 0.6 to 256 g/cm 2 ). How- ever, no genotoxicity was detected in duodenum and liver of male Sprague Dawley rats after 3 gavages as well as after 28 days oral treatment with 6, 12 and 25 mg/kg bw/day. This project was funded by Agence Nationale de la Recherche (ANR-13-IS10-0005-01).

Detection of carvacrol in biological tissues by analytical pyrolysis

Abstracts of the 52nd Congress of the European Societies of Toxicology (EUROTOX) Fibes Congress Center Seville, Spain, 04th-07th September 2016

Modification of cysteine residues by cyclopentenone prostaglandins in the elucidation of redox regulation of protein function

1 p. 52nd Congress of the European Societies of Toxicology (EUROTOX) Fibes Congress Center Seville, Spain, 04th-07th september 2016

Determination of propyl propane thiosulfonate in plasma and tissues by UHPLC–MS/MS orbitrap and analytical pyrolysis (Py-GC-MS)

Abstracts of the 52nd Congress of the European Societies of Toxicology (EUROTOX) Fibes Congress Center Seville, Spain, 04th-07th September 2016

Editorial

Editorial Communication - Dialogue - Co-operation - Solving problems. These are the words of nowadays Europe. Such approaches should be used in broad spectrum of life as well as in toxicology. It is therefore admirable that EUROTOX commissars, mainly past-president Prof. Liesivuori, invited all heads of European toxicological societies to discuss current issues of toxicology in Europe during IUTOX meeting held in Barcelona in July 2010. Renowned scientists and regulatory officers from Government, Industry and Academia made appearance and talked about contribution of toxicological research to society, importance of communication and education. The strategic meeting was successful. Prof. Liesivuori expressed gratitude to all delegates for the great suggestions and key findings resulting from the brainstorming sessions conducted during the meeting. Majority of delegates agreed that education in toxicology and related fields is the top priority for future. Communication towards society, in the sense of explaining possible risks, should be an important concern as well. Taking a good example from EUROTOX, on the verge of summer the Slovak Toxicology Society SETOX organizes meeting of the toxicological societies from the Central Europe, i.e. Slovak, Czech, Polish, Austrian and Hungarian societies of toxicology. First positive step was done by Visegrad Fund and Federation of European Toxicologists & European Societies of Toxicology, which supported this meeting. It is essential for successful co-operation to establish strong connections, which can be further crucial for meaningful and highly profitable information to society.

REGISTRATION OF TOXICOLOGISTS IN EUROPE

Recently several European Toxicological Societies have established national toxicology registers. Such societies include the British, Dutch, Finnish, French, Hungarian, and Swiss societies of toxicology. The basis for registration in these societies is peer review evaluation of the applicants. A key-criterion for acceptance is theoretical training covering the main areas of toxicology. Furthermore, job experience is required. After reviewing the merits of the applicant, the register then accepts the applicant to the register usually for five years. As a consequence of this development, EUROTOX, European Societies of Toxicology, has established a European Register of Toxicologists which will be officially inaugurated during 1997. The register already contains more than two hundred British, Dutch, Finnish, and German toxicologists. The European Register of Toxicologists already has had an impact on the recognition of toxicology in Europe, and will strive to promote toxicology education and professional status in other parts of the world.