Pesticide-free but non-organic production systems have been recently introduced in public and private programs in Europe. However, a key challenge is to define what ‘pesticide-free’ comprises and means. This paper aims to give insights in and critical reflections on the definition and regulation of pesticide-free crop production systems in real-world programs. To this end, we review four examples of public and private pesticide-free production programs in European crop production (i.e. from France, Germany and Switzerland). Our analysis reveals several semantic and regulatory inconsistencies and potential confusion that exists around the term pesticide-free crop production, i.e. we find that it is far from clear-cut what pesticide-free production systems are. For example, programs differ with respect to which part of the crop management cycle is regulated. Moreover, all programs offer various exceptions for pesticide use. Definitions and regulations differ widely across case studies. For example, to participate in governmental programs on pesticide-free production farmers in one country have different requirements than in another. Moreover, governmental regulations not match with those in private programs and vice versa. Pesticide-free production programs can be a useful and viable addition to European agricultural and food systems. However, based on the here presented insights, we formulate eight recommendations for policy and industry how to clarify, align and harmonize pesticide-free crop production.