In Khmer printed characters, same character has various shapes according to the fonts and some characters are very similar in shape. In this paper we try to solve these problems, and propose a method of Khmer printed character recognition by using Wavelet Descriptors. In the recognition, firstly the Khmer printed character images are converted to skeleton forms, then skeletons of Khmer character are converted to temporal domain. The templates are obtained by wavelet coefficients from the character training set. To match the input characters with templates, the character recognition method using deformable wavelet descriptor is adapted by using fixed template and Euclidean distance classifier for matching. The smallest distance is the recognition result of the proposed method. As a result, the deformation can be skipped because it might get low recognition rate of similar characters. The experiment consists of two parts. The first part is to evaluate the overall recognition rate of input characters with three different sizes (22-point, 18-point and 12-point) from 10 different fonts of Khmer printed character. Twenty styles of characters are used as the training set. The results show 92.85, 91.66, and 89.27 percent for 22-point, 18-point, and 12-point respectively. The second part is to specifically evaluate the system, testing with one document that has 21 pages of Khmer printed character with different resolutions from a scanner and facsimile (fax). The document is initially printed with 300 dpi (dots per inch), then scanned with three different resolutions, 600 dpi, 300 dpi and 150 dpi. The document that received from fax machine is scanned by 300 dpi. The results show 92.99, 88.61, and 80.05 percent recognition rate for 300, 150 dpi resolutions, and input from fax respectively.