The activity of Mt. Etna volcano from January 2011 to April 2012 was characterized by 24 paroxysmal, short-duration (from a few to several hours) eruptions at the New South-East summit crater. Despite the violence of the activity, no appreciable geophysical signals were recorded during this period, except for an increase in seismic tremors just minutes/hours before the occurrence of the paroxysm. This type of activity represents a significant shift from the mainly effusive eruptions of 2004, 2006, and 2008/2009, as well as from the lateral rift-related events of 2001 and 2002/2003.The 2011–2012 paroxysmal activity thus represents an important opportunity to better understand the effects of different magmatic parameters (i.e., P-T-fO2) and magmatic H2O content on the crystallization and fractionation processes. To this aim the petrographic and geochemical features of lava and scoria clasts from 10 paroxysmal events have been investigated. Fractional crystallization modelling indicates that most of the eruptions are related to magmas rising along the vertically-developed feeding system of the volcano, accompanied by one main recharge of a more primitive, deep-seated magma feeding the 4/3/2012 event. Olivine-, clinopyroxene-, and plagioclase-melt equilibria and thermobarometric calculations were performed in order to estimate the crystallization conditions of magmas. These calculations reveal that the erupted products contain different phenocryst populations in equilibrium with a spectrum of primitive to more evolved magma compositions. On the basis of crystal composition, crystal-melt equilibrium conditions and thermobarometric estimations, four main magmatic facies have been recognized: F1, 1600MPa at 1270°C (Ol Fo88); F2, 800MPa to 600MPa at 1178°C to 1151°C (Ol Fo84–78); F3, 450MPa to 250MPa at 1139°C to 1118°C (Ol Fo79–74); F4, <250MPa at <1120°C (Ol Fo75–70). The overall geochemistry and thermobarometric data allow us to characterize the central feeding system as continuous and vertically zoned. During the 2011–2012 activity the studied 30/7/11, 29/8/11, 8/9/11, 18/3/11 and 24/4/12 events were fed by magma residing at F3 and F4 facies. Mafic magma influx from deeper F2 facies occurred 18/2/11 and 20/8/11, with a major recharge event before the 4/3/12 eruption. The primitive magma is testified by rare olivine crystals equilibrated at the F1 facies, located at crust-mantle boundary depth and close to liquidus temperature.