Although social incubators provide a variety of entrepreneurial support, little is known regarding their design, implementation, operation and management. The identification and characterization of the clients and stakeholders of social incubators is complicated by multiple definitions of entrepreneurship and multiple typologies of entrepreneurs. Their ventures are accompanied by strategic and tactical confusion about objectives and populations served. This study investigates the dynamics of incubator clients’ needs and attributes as they interact with the values and interests of other stakeholders in a social incubator focused on survival entrepreneurs. Our sampling was a medium sized mixed economy town in Brazil. Our thirteen-month ethnographic study analyzed the collective struggle to transcend the tensions between social and economic values and improve the lives of vulnerable populations. Central to this struggle is the incubator management’s unique humanistic ideology coupled with the search for realistic concrete results modulated by community and client attributes. Through our analysis of various interventions that occurred within the social incubator, we discuss the importance of getting to know the vulnerable to better manage social incubators that focus on subsistence entrepreneurship. These contents are valued when discussed in the context of the evolutionary phases (or trajectory) of the vulnerable in a social incubator from welcoming through training, to improvement and other phases, until citizens’ autonomy is achieved.