Canada geese (Branta canadensis) were experimentally exposed to known amounts of lead. The course of the lead and of the disease in geese was followed, utilizing established laboratory procedures. Gross signs of lead poisoning first appeared 5-7 days following ingestion. The length of time until signs of disease or death occurred was related to the amount of lead ingested. Twenty-five or more pellets resulted in death within 10 days, while 10 or fewer pellets permitted survival as long as 72 days. Ingestion of large numbers of pellets resulted in a rapid increase of lead levels in the blood, acute poisoning, and early death. Ingestion of fewer pellets resulted in a slower increase of lead in the blood, chronic poisoning, and longer survival, with more typical lead poisoning signs and pathology. Lead pellets appeared to erode at a constant rate regardless of the number in the gizzard. The largest lead pellet volume (66 percent) was eroded within the first 3 days after exposure, and it took approximately 45 days for the remaining volume to disappear. Normal lead levels of blood for Canada geese were found to be 0.018-0.037 mg/100 g blood. The lead levels of blood of lead-poisoned geese lesions asmore » well as histological changes are described. High lead levels in blood and liver tissue, significance and effect of lead poisoning on the fecundity of geese are discussed. 21 references, 3 figures, 2 tables.« less