Alaska Eskimos Research Articles

Genetic history of the Koryaks and Evens of the Magadan region based on Y chromosome polymorphism data.

In order to clarify the history of gene pool formation of the indigenous populations of the Northern Priokhotye (the northern coast of the Sea of Okhotsk), Y-chromosome polymorphisms were studied in the Koryaks and Evens living in the Magadan region. The results of the study showed that the male gene pool of the Koryaks is represented by haplogroups C-B90-B91, N-B202, and Q-B143, which are also widespread in other peoples of Northeastern Siberia, mainly of Paleo-Asiatic origin. High frequency of haplogroup C-B80, typical of other Tungus-Manchurian peoples, is characteristic of the Evens of the Magadan region. The shared components of the gene pools of the Koryaks and Evens are haplogroups R-M17 and I-P37.2 inherited as a result of admixture with Eastern Europeans (mainly Russians). The high frequency of such Y chromosome haplogroups in the Koryaks (16.7 %) and Evens (37.8 %) is indicative of close interethnic contacts during the last centuries, and most probably especially during the Soviet period. The genetic contribution of the European males' Y chromosome significantly prevails over that of maternally inherited mitochondrial DNA. The study of the Y chromosome haplogroup diversity has shown that only relatively young phylogenetic branches have been preserved in the Koryak gene pool. The age of the oldest component of the Koryak gene pool (haplogroup C-B90-B91) is estimated to be about 3.8 thousand years, the age of the younger haplogroups Q-B143 and N-B202 is about 2.8 and 2.4 thousand years, respectively. Haplogroups C-B90-B91 and N-B202 are Siberian in origin, and haplogroup Q-B143 was apparently inherited by the ancestors of the Koryaks and other Paleo-Asiatic peoples from the Paleo-Eskimos as a result of their migrations to Northeast Asia from the Americas. The analysis of microsatellite loci for haplogroup Q-B143 in the Eskimos of Greenland, Canada and Alaska as well as in the indigenous peoples of Northeastern Siberia showed a decrease in genetic diversity from east to west, pointing to the direction of distribution of the Paleo-Eskimo genetic component in the circumpolar region of America and Asia. At the same time, the Evens appeared in the Northern Priokhotye much later (in the XVII century) as a result of the expansion of the Tungusic tribes, which is confirmed by the results of the analysis of haplogroup C-B80 polymorphisms.

Adoption and adaptation in Iñupiat fashion: Past and present

This article presents and discusses the development of Iñupiat (North Alaskan Inuit) fashion of atikłuk (‘inner garment’) and atigi (‘outerwear’) over time, with a focus on adoption and adaptation, linked to the concept of cultural authentication. It is based on the author’s fieldwork in the winter of 1997 and the summer of 1998, which included participant observations and interviews with seamstresses from the Iñupiat villages of Kaktovik and Utqiaġvik at the North Slope of Alaska, literature reviews, observations from museums and archival photos. The second part of this article involves a case study that focuses on a young Iñupiat trans woman and her mother in 2022. Together they designed a new fabric (instead of leather) for an atikłuk. The case show how she adopts the contemporary Iñupiat garment and adapts it to her own style.

Inuit-defined determinants of food security in academic research focusing on Inuit Nunangat and Alaska: A scoping review protocol.

Academic research on food security in Inuit Nunangat and Alaska frequently adopts the Food and Agriculture Organization of the United Nations' working definition of food security and Western conceptualisations of what it means to be 'food secure'. However, in 2014, the Alaskan branch of the Inuit Circumpolar Council (ICC) stated that academic and intergovernmental definitions and understandings 'are important, but not what we are talking about when we say food security'. The organisation subsequently developed its own conceptualisation and definition: the Alaskan Inuit Food Security Conceptual Framework (AIFSCF), which in 2020 received informal assent by ICC-Canada. This protocol establishes a review strategy to examine how well academic research reflects Inuit conceptualisations and understandings of food security, as outlined in the AIFSCF. Review structure and reporting will be completed according to adapted RepOrting standards for Systematic Evidence Syntheses (ROSES) guidelines. A comprehensive search strategy will be used to locate peer-reviewed research from Medline, Scopus, Web of Science and the Arctic and Antarctic Regions (EBSCO) databases. Dual reviewer screening will take place at the abstract, title, and full-text stages. Different study methodologies (qualitative, quantitative, and mixed methods) will be included for review, on the proviso that articles identify drivers of food security. An a priori coding framework will be applied by a single reviewer to extract data on publication characteristics, methods and article aims. Deductive thematic content analysis will then identify the frequency and precedence afforded within literature to the drivers and dimensions of food security identified by the AIFSCF.

Psychological Portrait of the Eskimos of Alaska Based on Russian Historical Sources (1763–1867)

Psychological Portrait of the Eskimos of Alaska Based on Russian Historical Sources (1763–1867)

Relational Identities and Other-Than-Human Agency in Archaeology

Relational Identities and Other-Than-Human Agency in Archaeology

Symmetry and Measuring: Ways to Teach the Foundations of Mathematics Inspired by Yupiaq Elders

Evident in human prehistory and across immense cultural variation in human activities, symmetry has been perceived and utilized as an integrative and guiding principle. In our long-term collaborative work with Indigenous Knowledge holders, particularly Yupiaq Eskimos of Alaska and Carolinian Islanders in Micronesia, we were struck by the centrality of symmetry and measuring as a comparison-of-quantities, and the practical and conceptual role of qukaq [center] and ayagneq [a place to begin]. They applied fundamental mathematical principles associated with symmetry and measuring in their everyday activities and in making artifacts. Inspired by their example, this paper explores the question: Could symmetry and measuring provide a systematic and integrative way to teach the foundations of mathematical thinking? We illustrate how the fundamental structures of symmetry, measuring, and comparison-of-quantities, starting with the embodied orthogonal axes, form a basis for properties of equality, aspects of numbers and operations (including place value), geometry and number line representations, functions, algebraic reasoning, and measurement. We conclude by embedding the earlier geometric constructions of triangles and squares within the unit circle and making explicit connections to trigonometric functions.

Mandibular ramus shape variation and ontogeny in Homo sapiens and Homo neanderthalensis

As the interface between the mandible and cranium, the mandibular ramus is functionally significant and its morphology has been suggested to be informative for taxonomic and phylogenetic analyses. In primates, and particularly in great apes and humans, ramus morphology is highly variable, especially in the shape of the coronoid process and the relationship of the ramus to the alveolar margin. Here we compare ramus shape variation through ontogeny in Homo neanderthalensis to that of modern and fossil Homo sapiens using geometric morphometric analyses of two-dimensional semilandmarks and univariate measurements of ramus angulation and relative coronoid and condyle height. Results suggest that ramus, especially coronoid, morphology varies within and among subadult and adult modern human populations, with the Alaskan Inuit being particularly distinct. We also identify significant differences in overall anterosuperior ramus and coronoid shapes between H. sapiens and H. neanderthalensis, both in adults and throughout ontogeny. These shape differences are subtle, however, and we therefore suggest caution when using ramus morphology to diagnose group membership for individual specimens of these taxa. Furthermore, we argue that these morphologies are unlikely to be representative of differences in masticatory biomechanics and/or paramasticatory behaviors between Neanderthals and modern humans, as has been suggested by previous authors. Assessments of ontogenetic patterns of shape change reveal that the typical Neanderthal ramus morphology is established early in ontogeny, and there is little evidence for divergent postnatal ontogenetic allometric trajectories between Neanderthals and modern humans as a whole. This analysis informs our understanding of intraspecific patterns of mandibular shape variation and ontogeny in H. sapiens and can shed further light on overall developmental and life history differences between H. sapiens and H. neanderthalensis.

Eco-geographic adaptations in the human ribcage throughout a 3D geometric morphometric approach.

According to eco-geographic rules, humans from high latitude areas present larger and wider trunks than their low-latitude areas counterparts. This issue has been traditionally addressed on the pelvis but information on the thorax is largely lacking. We test whether ribcages are larger in individuals inhabiting high latitudes than in those from low latitudes and explored the correlation of rib size with latitude. We also test whether a common morphological pattern is exhibited in the thorax of different cold-adapted populations, contributing to their hypothetical widening of the trunk. We used 3D geometric morphometrics to quantify rib morphology of three hypothetically cold-adapted populations, viz. Greenland (11 individuals), Alaskan Inuit (8 individuals) and people from Tierra del Fuego (8 individuals), in a comparative framework with European (Spain, Portugal and Austria; 24 individuals) and African populations (South African and sub-Saharan African; 20 individuals). Populations inhabiting high latitudes present longer ribs than individuals inhabiting areas closer to the equator, but a correlation (p < 0.05) between costal size and latitude is only found in ribs 7-11. Regarding shape, the only cold adapted population that was different from the non-cold-adapted populations were the Greenland Inuit, who presented ribs with less curvature and torsion. Size results from the lower ribcage are consistent with the hypothesis of larger trunks in cold-adapted populations. The fact that only Greenland Inuit present a differential morphological pattern, linked to a widening of their ribcage, could be caused by differences in latitude. However, other factors such as genetic drift or specific cultural adaptations cannot be excluded and should be tested in future studies.

Interpretation of the world through folklore (based on Chukotka and Alaska Eskimos data)

Interpretation of the world through folklore (based on Chukotka and Alaska Eskimos data)

Toward Precision Medicine: TBC1D4 Disruption Is Common Among the Inuit and Leads to Underdiagnosis of Type 2 Diabetes.

A common nonsense mutation in TBC1D4 was recently found to substantially increase the odds of type 2 diabetes in Greenlandic Inuit, leading to exclusively increased postprandial glucose. We investigated the frequency and effect of the TBC1D4 mutation on glucose metabolism and type 2 diabetes diagnosis among Canadian and Alaskan Inuit. Exome sequencing of the TBC1D4 variant was performed in 114 Inuit from Nunavik, Canada, and Sanger sequencing was undertaken in 1,027 Alaskan Inuit from the Genetics of Coronary Artery Disease in Alaskan Natives (GOCADAN) Study. Association testing evaluated the effect of the TBC1D4 variant on diabetes-related metabolic traits and diagnosis. The TBC1D4 mutation was present in 27% of Canadian and Alaskan Inuit. It was strongly associated with higher glucose (effect size +3.3 mmol/L; P = 2.5 x 10-6) and insulin (effect size +175 pmol/L; P = 0.04) 2 h after an oral glucose load in homozygote carriers. TBC1D4 carriers with prediabetes and type 2 diabetes had an increased risk of remaining undiagnosed unless postprandial glucose values were tested (odds ratio 5.4 [95% CI 2.5-12]) compared with noncarriers. Of carriers with prediabetes or type 2 diabetes, 32% would remain undiagnosed without an oral glucose tolerance test (OGTT). Disruption of TBC1D4 is common among North American Inuit, resulting in exclusively elevated postprandial glucose. This leads to underdiagnosis of type 2 diabetes, unless an OGTT is performed. Accounting for genetic factors in the care of Inuit with diabetes provides an opportunity to implement precision medicine in this population.

Morphological Covariation between the Maxillary Sinus and Midfacial Skeleton among Sub-Saharan and Circumpolar Modern Humans.

Maxillary sinus volume tracks ecogeographic differences in nasal form and may serve as a zone of accommodation for ontogenetic and evolutionary changes in nasal cavity breadth. However, little is known regarding how sinus volume is distributed within the midface. This study investigates morphological covariation between midfacial and sinus shape to better understand structural and functional relationships between the sinus, midface, and nasal cavity. Cranial and sinus models were rendered from CT scans of modern human samples from two disparate climates: sub-Saharan (South Africans [n = 15], West Africans [n = 17]), and circumpolar (Siberian Buriats [n = 18], Alaskan Inuit [n = 20]). Twenty-five 3D coordinate landmarks were placed on the models and subjected to generalized Procrustes analysis. Two-block partial least squares (2B-PLS) analysis was employed to identify patterns of covariation. The 2B-PLS analysis indicates PLS1 (58.6% total covariation) relates to height and breadth relationships between the midface, nasal cavity, and maxillary sinus. Significant regional differences in PLS1 scores are evident: circumpolar samples possess taller/narrower noses with taller/wider sinuses compared to sub-Saharan samples. Importantly, PLS1 indicates that sinus breadth is not exclusively related to nasal cavity breadth; variation in lateral sinus expansion toward the zygoma represents an important contributing factor. PLS2 (16%) relates to supero-inferior positioning of the sinus within the midface. Allometric trends, while statistically significant, explain only a small portion of these covariation patterns. These results suggest that the maxillary sinus serves as a zone of accommodation at the confluence of multiple facial components, potentially minimizing effects of morphological alterations to certain components on adjacent structures. Am J Phys Anthropol 160:483-497, 2016. © 2016 Wiley Periodicals, Inc.

The role of dietary creatine.

The daily requirement of a 70-kg male for creatine is about 2g; up to half of this may be obtained from a typical omnivorous diet, with the remainder being synthesized in the body Creatine is a carninutrient, which means that it is only available to adults via animal foodstuffs, principally skeletal muscle, or via supplements. Infants receive creatine in mother's milk or in milk-based formulas. Vegans and infants fed on soy-based formulas receive no dietary creatine. Plasma and muscle creatine levels are usually somewhat lower in vegetarians than in omnivores. Human intake of creatine was probably much higher in Paleolithic times than today; some groups with extreme diets, such as Greenland and Alaskan Inuit, ingest much more than is currently typical. Creatine is synthesized from three amino acids: arginine, glycine and methionine (as S-adenosylmethionine). Humans can synthesize sufficient creatine for normal function unless they have an inborn error in a creatine-synthetic enzyme or a problem with the supply of substrate amino acids. Carnivorous animals, such as lions and wolves, ingest much larger amounts of creatine than humans would. The gastrointestinal tract and the liver are exposed to dietary creatine in higher concentrations before it is assimilated by other tissues. In this regard, our observations that creatine supplementation can prevent hepatic steatosis (Deminice et al. J Nutr 141:1799-1804, 2011) in a rodent model may be a function of the route of dietary assimilation. Creatine supplementation has also been reported to improve the intestinal barrier function of the rodent suffering from inflammatory bowel disease.

Dietary supplements: health from the ocean?

Dietary supplements: health from the ocean?

Loosening Lips to Avoid Sinking Ships: Designing a Ship Communications System for the Bering Strait Region

This article compares systems that regulate ship traffic and communications and discusses the legal requirements for each one. It provides recommendations for a regulatory system for the Bering Strait and its surrounding waters—a remote and ecologically important region that is vulnerable to damage from increasing Arctic ship traffic. In cooperation with its Russian counterpart, the United States Coast Guard could work through the International Maritime Organization to establish a ship reporting system, a ship routing system, and/or vessel traffic services, as well as special areas that would be subject to additional regulatory measures. In designing a system, the Coast Guard should consider the Alaska Eskimo Whaling Commission reporting system already in place for oil and gas vessels in waters off the coast of Alaska. 582 IND. INT’L & COMP. L. REV. [Vol. 24:3

Of whales and oil: Inuit resource governance and the Arctic Council

ABSTRACTThis article takes a normative approach to explore what and how we might learn from existing indigenous governance arrangements in the Arctic and how they may contribute to the larger debates over Arctic governance and who decides. It begins with a brief exploration of the existing literature regarding co-management; particularly what some legal scholars have defined as post-Westphalian resource management as well as engaging ongoing discussions about co-management as it pertains to the Arctic. It then turns to the Alaska Eskimo Whaling Commission (AEWC) as a case study and possible starting point for governing newly emerging resource management issues in the Arctic. Specifically, this article will look at how the governance framework of the AEWC might be applicable for the current governance discussions regarding Arctic offshore oil and gas development. Lastly, this paper will offer preliminary reflections as to how a post-sovereign resource management approach could contribute to the broader theoretical debates concerning who owns the Arctic and who decides. Specifically it offers one possible way to envisage the future of a strengthened Arctic Council operating in a world where states are not the only actors participating in the governance of the Arctic.

Lipoprotein subfractions and dietary intake of n-3 fatty acid: the Genetics of Coronary Artery Disease in Alaska Natives study

Few studies have compared lipoprotein composition with dietary intake. The lipoprotein subfraction profile was evaluated in relation to diet in Alaska Eskimos at high cardiovascular risk but with a low frequency of hyperlipidemia and high intake of n-3 (omega-3) fatty acids. A population-based sample (n = 1214) from the Norton Sound Region of Alaska underwent a physical examination and blood sampling. Analyses were from 977 individuals who did not have diabetes or use lipid-lowering medications and had complete dietary information (food-frequency questionnaire) and a lipoprotein subfraction profile (nuclear magnetic resonance spectroscopy). After adjustment for age, BMI, total energy intake, and percentage of energy from fat, the intake of n-3 fatty acids was significantly associated with fewer large VLDLs (P = 0.022 in women, P = 0.064 in men), a smaller VLDL size (P = 0.018 and P = 0.036), more large HDLs (P = 0.179 and P = 0.021), and a larger HDL size (P = 0.004 and P = 0.001). After adjustment for carbohydrate and sugar intakes, large VLDLs (P = 0.042 and 0.018) and VLDL size (P = 0.011 and 0.025) remained negatively associated with n-3 fatty acid intake in women and men, and large HDLs (P = 0.067 and 0.005) and HDL size (P = 0.001 in both) remained positively associated with n-3 fatty acid intake in women and men. In addition, large LDLs (P = 0.040 and P = 0.025) were positively associated in both sexes, and LDL size (P = 0.006) showed a positive association in women. There were no significant relations with total LDL particles in either model. Dietary n-3 fatty acids, independent of the reciprocal changes in carbohydrate and sugar intakes, are associated with an overall favorable lipoprotein profile in terms of cardiovascular risk. Because there are no relations with total LDL particles, the benefit may be related to cardiovascular processes other than atherosclerosis.

Lewis R. Binford's Impact on Zooarchaeology

Zooarchaeology asked the same research questions and answered them the same ways between 1950 and 1980. Change occurred when actualistic research revealed that the taphonomy of a collection of faunal remains could significantly skew interpretations. Lewis Binford's ethnoarchaeological work among Alaskan Inuit peoples focused on how human behaviors created bone assemblages and how carnivore behaviors influenced those bone assemblages. That research provided new interpretive models based on the frequencies of prey-carcass parts and their economic utility. Binford published a wealth of actualistic data and his models on economic utility in his 1978 book <i>Nunamiut Ethnoarchaeology.</i> In his 1981 book <i>Bones: Ancient Men and Modern Myths</i> and his 1984 book <i>Faunal Remains from Klasies River Mouth</i>, he used the Nunamiut models and suggested that our early hominid ancestors scavenged much of the meat they consumed contrary to the then popular view that those ancestors were hunters. Binford's legacy to zooarchaeology can be considered revolutionary in a Kuhnian sense because that legacy comprises major alterations to how we analyze and interpret faunal remains, as well as significant changes to what we think we know about the behaviors of our early hominid ancestors.

Stable carbon and nitrogen isotopes of human dental calculus: a potentially new non-destructive proxy for paleodietary analysis

Fifty-eight dental calculus samples from medieval and post-medieval skeletons from Vitoria, Spain, and a single sample from an Alaskan Inuit were tested for stable carbon and nitrogen isotope compositions. There was sufficient carbon and nitrogen concentrations to obtain δ13C and δ15N values, and the samples from Spain produced results that were replicable and comparable to European isotope values based on bone collagen collected from literature sources. The Alaskan Inuit calculus sample yielded a δ15N value of +17.5‰, well beyond the range of the Spanish samples, but consistent with literature data for modern Greenlandic Inuit consuming a diet rich in marine food. There are several potential sources for carbon and nitrogen in calculus. The results of this study yield stable isotope values consistent with those obtained from other biomaterials used as isotope proxies for paleodietary research, including bone collagen, hair, and fingernails, although further work is necessary to verify the fidelity of calculus as an isotope proxy. Many studies in bioarchaeology are precluded by curatorial concerns regarding the destructive analysis of primary biomaterials. However, calculus is an “add-on”, or secondary biomaterial, that is not an integral part of the dental or skeletal system. Hence, its consumption during analysis is technically not destructive. Therefore, isotope analysis of dental calculus may provide a potential new avenue for paleodietary analysis where the use of other primary biomaterials is precluded.

Uric Acid, Hypertension, and Chronic Kidney Disease Among Alaska Eskimos: The Genetics of Coronary Artery Disease in Alaska Natives (GOCADAN) Study

It is unknown what role uric acid (UA) may play in the increasing rates of cardiovascular disease (CVD) among Alaska Eskimos. UA is associated with both hypertension (HTN) and chronic kidney disease (CKD). The authors analyzed 1078 Genetics of Coronary Artery Disease in Alaska Natives (GOCADAN) participants. Estimated glomerular filtration rate (eGFR) was calculated from serum creatinine measures using the Modification of Diet in Renal Disease equation. CKD was defined by an eGFR of <60 mL/min/1.73 m(2) . The authors adjusted for age, sex, education, diabetes, hypertension (or eGFR), obesity, lipids, and smoking status; 7% (n=75) had prevalent CKD. eGFR decreased with increasing tertiles of serum UA (P<.001). UA was independently associated with prevalent CKD (adjusted odds ratio [OR] and 95% confidence interval [CI] of 2.04 (1.62-2.56), respectively). Twenty-one percent (n=230) had prevalent HTN and UA was independently associated with prevalent HTN (adjusted OR, 1.2; 95% CI, 1.1-1.5). UA is independently associated with prevalent CKD and HTN in this population.

Determinants of Cardiovascular Disease in the 21st Century- -Insights from Two Diverse Populations

Seminal work by Ancel Keys established the critical role of elevated cholesterol in explaining population differences in rates of CVD. Subsequent work added hypertension and smoking, and major progress has been made in controlling all three. Despite this, world-wide rates of CVD are increasing, and in the US, there are persistent population disparities. We have conducted longitudinal cohort studies in two uniquely-informative populations in order to evaluate the determinants of CVD. The Strong Heart Study is a population based sample of American Indians. Although little CVD was observed in the mid 20 th century, rates of both CHD and stroke now exceed those in other US populations. Most events are in persons with diabetes; renal impairment is another major risk factor. Both obesity and diabetes lead to CVD risk factors and preclinical disease at young ages. The GOCADAN (Genetics of Coronary Artery Disease in Alaska Natives) and ASP (Alaska-Siberia Project) studies involve populations of Alaska Eskimos. Once thought to have little CVD, they now manifest high rates of CHD, stroke and heart failure. Obesity and diabetes in this population are lower than US averages, especially in men. However rates of smoking and subclinical infection are high and there has been a dramatic change from their unique traditional diet and physical activity patterns. These two groups serve as models for the many populations now experiencing increases in CVD. For those with epidemics of obesity and diabetes, control of the inevitable CVD will require both aggressive management of CVD risk factors and reversing the trends in obesity and diabetes. In other populations, perhaps in less developed areas, control of CVD may depend on aggressive smoking cessation and on efforts to facilitate lifestyle transitions.