P0008 The role and preliminary mechanism of erythritol in acute DSS-induced colitis and depressive behaviors in mice

As renewable energytechnologies continue to advance, supercooledphase change materials (PCMs) are emerging as a promising solutionfor long-term thermal energy storage (TES), gaining significant attentionfrom both researchers and industry for their potential to enhanceenergy efficiency. In our previous study, a supercooled PCMs systemthat blended erythritol (ET) and d-mannitol (DM) was shownto exhibit high latent heat but could not achieve long-term thermalstorage stability. To extend the thermal storage duration of the previousDM/ET (DE) material, it served as a foundation that was integratedwith sodium alginate (SA) to produce novel SA/DE PCMs. Experimentalresults demonstrated that the subject SA/DE PCMs were stable after3 months of room-temperature storage (approximately 10–30 °C)attributed to intermolecular hydrogen bonding between hydroxyl groupsof SA and DE. When the SA content was 3 wt %, the mixture exhibiteda maximum cold-crystallization enthalpy (ΔHcc) of 199.0 J/g, which was approximately 97.0% of pureDE’s ΔHcc value. Furthermore,this material exhibited excellent cyclic stability, and the storedlatent heat could be controllably released through different triggers.This study opens new pathways for long-term thermal energy storageand dispatchable utilization, showing great promise for renewableenergy integration and carbon-neutral technologies.

Organic phase-change materials (PCMs) offer great promise in addressing challenges in thermal energy storage and heat management, but their applications are greatly limited by low energy density and a rigid phase transition temperature. Herein, by introducing carbon dots (CDs) with abundant oxygen-related groups, we develop a novel kind of erythritol (ET)-based composite PCMs (CD-ETs) featuring an enhanced latent heat storage capacity and a reduced degree of supercooling compared to pure ETs. The optimally formulated CD-ETs increase the latent heat storage capacity from 377.3 to 410.2 J·g−1 and the heat release capacity from 209.0 to 240.2 J·g−1 compared to the pristine ETs. Moreover, the subcooled degree of CD-ETs is more than 30 °C lower than that of pristine ETs. By successively encapsulating CD-ETs and CD-containing polyethylene glycol (PEG) with a low melting point in a reduced graphene oxide-modified melamine sponge, the resultant shape-stabilized system not only prevents leakage of molten PCMs but also allows for a wide response temperature window and promotes the heat transfer ability of melted PEG in close contact with solid CD-ETs. Stepped melting and crystallization guarantee phase changes in high-melting-point ETs via solar heating, Joule heating or a combination thereof. Specifically, the melting enthalpy of this system is as high as 306.5 J·g−1, and its cold crystallization enthalpy reaches 196.5 J·g−1, surpassing numerous organic PCMs. This work provides a facile and efficient strategy for the design of ideal thermal energy storage materials to meet the needs of application scenarios in a cost-effective manner.

Preparation and properties of erythritol form-stable phase change materials supported by composite aerogels derived from cellulose and silica.

Research on the effects of different sugar substitutes-Mogroside V, Stevioside, Sucralose, and Erythritol-On glucose, lipid, and protein metabolism in type 2 diabetic mice.

Intestinal health disorders significantly contribute to the development of type 2 diabetes mellitus (T2DM). Sugar substitutes such as mogroside V (MOG), stevioside (ST), sucralose (TGS), and erythritol (ERT), are increasingly used in T2DM management as alternatives to sucrose (SUC). However, their effects on intestinal health in T2DM have not been fully compared. In the present study, we established a T2DM mouse model using a high-fat diet and streptozotocin injection. These mice were treated with equal doses of SUC, MOG, ST, TGS, or ERT for 4 weeks to evaluate the effects of these sugar substitutes on intestinal health in T2DM. T2DM mice exhibited increased intestinal permeability, reduced goblet cell numbers, elevated pro-inflammatory cytokine levels, and alterations in both gut microbiota and metabolite composition. After 4 weeks of treatment, MOG showed the most significant benefits. MOG activates the PI3K/AKT pathway, enhancing the expression of tight junction proteins, which improves intestinal barrier function and reduces permeability. This is accompanied by NF-κB inhibition, leading to reduced pro-inflammatory cytokine production and increased mucus secretion. These changes help maintain healthy gut microbiota and metabolites, preventing pathogenic bacteria from entering the bloodstream. ST downregulates NF-κB to alleviate intestinal inflammation and improves gut microbiota and metabolic homeostasis in T2DM. ERT has less beneficial effects. TGS and SUC reduce intestinal inflammation and have a better effect on the duodenum. However, TGS has a negative effect on the colon microbiota and metabolites, whereas SUC has a negative effect on the colon microbiota alone. MOG improved intestinal health in T2DM by modulating the PI3K/AKT and NF-κB pathways, whereas ST primarily modulated NF-κB to alleviate intestinal inflammation. Both treatments were effective, with MOG showing the best performance. Therefore, MOG can be considered a viable alternative to SUC for T2DM management.

Controllable heat release of supercooled Erythritol-based phase change materials for long-term thermal energy storage

Transcriptional regulation of multi-tissue mRNA expression by L-arabinose mitigates metabolic disorders in leptin receptor-deficient mice

Abstract Excellent oxygen barrier films were prepared by blending very small loadings (<1 wt%) of dihydroxyacetone (DHA), erythritol (ET) or xylitol (XT) in thermoplastic starch (TPS), and/or processing with supercritical carbon dioxide (scCO2) assistance. The minimum oxygen transmission rates (OTR) and all free-volume-hole characteristic (FVH) values of each scCO2-processed TPS/sugar alcohol film series are somewhat smaller than those of corresponding TPS/sugar alcohol film series without scCO2-assistance, and decrease with the decrease in sugar alcohol’s molecular weight. The minimum OTR values acquired for scCO2-processed TPS/DHA and TPS/ET blown films are only 3.6 and 4.3 cm3/m2·day·atm, respectively, which meet the demand of high oxygen barrier films having OTR ≦5 cm3/m2·day·atm. The longitudinal or transversal tensile strengths acquired for each scCO2-processed TPS/sugar alcohol series films are ∼30 % to ∼40 % higher than those of the TPS blown films. Dynamic mechanical relaxations of each TPS/sugar alcohol or scCO2-processed TPS/sugar alcohol film series reveal that the sugar alcohols are compatible with TPS, as their sugar alcohol contents are ≤ the corresponding compatibility values. The decreased OTR and FVH values acquired for TPS/sugar alcohol or scCO2-processed TPS/sugar alcohol films are most likely due to them being scCO2-processed or incorporated with smaller molecular weight of sugar alcohols.

This study investigated the impact of erythritol (ERY) on structural and functional properties of whey protein isolate (WPI). FTIR and CD revealed that WPI underwent structural changes, including formation of β‐folds and random coils, upon interaction with 20 mg/mL ERY. SEM showed increased surface roughness of WPI, indicating enhanced protein exposure. Moreover, binding rate exceeded 85%, accompanied by increased surface hydrophobicity. Fluorescence spectroscopy indicated a red shift in fluorescence of WPI and tyrosine (Tyr) residues, altering polarity of Tyr environment due to ERY coordination. Additionally, ERY presence enhanced the functional properties of WPI, including foaming, freeze–thaw stability, rheology and antioxidant activity.

Preparation and characterization of phase change erythritol/expanded graphite@Ag composite materials for thermal energy storage

Abstract Fully renewable oxygen barrier thermoplastic starch (TPS)/sugar alcohol blown films were innovatively prepared by blending proper loadings of Erythritol (ET), Sorbitol (ST), and Lactitol (LT) and supercritical carbon dioxide (scCO 2 ) assistance. The oxygen transmission rate (OTR) values of the properly prepared scCO 2 TPS x ET y , scCO 2 TPS x ST y, and scCO 2 TPS x LT y films reduced to 4.3, 6.6, and 12.5 cm 3 /m 2 ∙day∙atm, which are about 5–28 times smaller than those of the conventional TPS films reported in the literature. The free‐volume‐cavity characteristics (FVCC) and OTR detected for TPS x ET y (or scCO 2 TPS x ET y ), TPS x ST y (or scCO 2 TPS x ST y ), and TPS x LT y (or scCO 2 TPS x LT y ) films diminished to a minimum, as their ET, ST and LT loadings came near an optimal value. Slightly smaller OTR and FVCC values were detected for scCO 2 TPS x ET y , scCO 2 TPS x ST y, and scCO 2 TPS x LT y films than those of corresponding TPS x ET y , TPS x ST y , and TPS x LT y films prepared without scCO 2 ‐assistance. The smallest OTR and FVCC detected for the properly prepared TPS x ET y (or scCO 2 TPS x ET y ), TPS x ST y (or scCO 2 TPS x ST y ), and TPS x LT y (or scCO 2 TPS x LT y ) films diminished with decreasing sugar alcohol's molecular weight. An essential result is that the OTR of the properly prepared scCO 2 TPS x ET y film was merely 4.3 cm 3 /m 2 ∙day∙atm, which is small enough to meet the demand of high oxygen barrier packaging application. Dynamic molecular relaxations detected for these films disclosed that ET, ST, and LT were compatible with TPS, as their loads were ≤ the optimum value. The distinctly reduced OTR and FVCC for these properly prepared films are partially attributed to the reinforced molecular interactions between sugar alcohol and TPS's hydroxyl groups when they were prepared with scCO 2 ‐assistance, optimal sugar alcohol loading, and/or smaller sugar alcohol's molecular weight. Highlights High oxygen barrier thermoplastic starch/sugar alcohol blown films were prepared. The lowest oxygen transmission rate of the renewable film was 4.3 cm 3 /m 2 ∙day∙atm. This oxygen transmission rate is qualified for high oxygen barrier application. Boosted oxygen barrier property was ascribed to the reduced free volume values.

Polyol grafted thin film nanocomposite membrane: Enhanced pervaporation performance for isopropanol dehydration

Thermal property optimization and shape stabilization of sugar alcohols phase change thermal energy storage materials reinforced by sintering synthesized alumina porous ceramics

Shape-stable erythritol composite phase change materials with controlled latent heat release for spatiotemporally thermal energy utilization

Preparation of alumina/silica/exfoliated graphite nanoplatelets composite aerogels and its application as supporting material for erythritol based form-stable phase change materials

In this study, an advanced phase change material (PCM) was fabricated to combine the properties of a biobased thermoplastic polymer and the heat storage of PCM to overcome the limitations of the existing PCM composites. The novel PCM of erythritol (ET)-grafted polylactic acid (PLA) (ETPLA) was prepared by the in situ polymerization of ET and PLA. The thermally conductive ETPLA composites were fabricated by injection molding using a hybrid filler system of oxidized carbon fiber (CF-OH) and aluminum nitride (AlN), which showed a high through-plane thermal conductivity of 4.25 W/mK, a tensile strength of 16.4 MPa (1953% enhancement comparing pure ET), an elongation at break of 4.4% (189% enhancement comparing pure ET), and latent heat of 170.7 J/g. Thus, the ETPLA/CF-OH/AlN composites facilitate efficient thermal management to combine heat saving and heat dissipation through the large latent heat and high thermal conductivity. Thus, the fabricated PCM composites have potential applications in thermal management systems of next-generation electronic devices.

Rhenium modified Pt/TiO2 catalyst has been tested during erythritol (ERY) hydrogenolysis reaction in a slurry reactor. N2 physisorption, temperature programmed reduction and CO chemisorption characterizations were performed. After reduction treatment, Pt species were fully reduced with a dispersion of 26% whereas Re species remained partially oxidized. ERY may convert through four pathways: isomerization, dehydration and C-O or C-C hydrogenolysis. Pt-Re/TiO2 was active and selective to butanetriols and butanediols formation. The influence of temperature (423–498 K) and reactant concentrations (15-35 barH2 and 0.2-0.6 MERY) on catalytic activity and products distribution were evaluated; the activation energy and the reaction orders for each route were estimated. Dehydration pathway displayed the highest activation energy whereas isomerization showed the lowest value. The order to ERY and H2 were 0.23 and 0.97 respectively, for C-O hydrogenolysis route and is consistent with two different mechanisms proposed for the removal of primary or secondary OH group.

Design of a graphene oxide@melamine foam/polyaniline@erythritol composite phase change material for thermal energy storage

Ni@rGO into nickel foam for composite polyethylene glycol and erythritol phase change materials