In this paper, we provide a unified framework for the asymptotic performance analysis of space-time codes (STCs) in correlated Ricean fading and non-Gaussian noise and interference. In particular, we derive simple and asymptotically tight expressions for the pairwise error probability (PEP) of coherent and differential STCs which are valid for any type of noise and interference with finite moments and detection with general Mahalonobis distance (MD) metrics including Euclidean distance (ED) and noise decorrelating (ND) metrics. These PEP expressions can be combined with truncated union bounds to obtain accurate asymptotic approximations for the bit, symbol, and frame error probabilities of STCs. We show that while the diversity gain of an STC is independent of the type of noise and the type of MD metric used, the coding gain is not and depends on certain moments of the noise and interference. We provide closed-form expressions for these moments for several practically relevant types of noise and interference. We show that for correlated noise significant performance gains can be achieved with the ND metric compared to the ED metric. While noise correlations are beneficial at high signal-to-noise ratios if they can be exploited by the metric, they are harmful if this is not the case and the simple ED metric is employed. All our analytical findings are confirmed by simulations for various popular STCs and several different types of noise and interference.